Bus Baltimore, MD to Florence, SC - Compare all Companies

Compare all timetables for the bus from Baltimore, MD to Florence, SC

Here is a selection of the cheapest bus trips from the schedule from Baltimore, MD to Florence, SC from various bus operators like Wanda Coach, Greyhound US or FlixBus for the next days.

today

$94

tomorrow

$100

Sunday

$89

Monday

$85

Tuesday

Wednesday

Thursday

$100

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	12h 0m	11:45 PM	Baltimore, MD	Downtown Bus Station	11:45 AM	Florence, SC	Bus Station		Economy	$94	A Bus from Greyhound US goes from Downtown Bus Station, Baltimore, MD (USA) at 12/12/2025 11:45:00 PM to Bus Station, Florence, SC (USA) arriving at 12/13/2025 11:45:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 12h 0m
	Wanda Coach	8h 50m	11:10 PM	Baltimore, MD	Focus Travel	8:00 AM	Florence, SC	Exxon Gas Station		Economy	$100	A Bus from Wanda Coach goes from Focus Travel, Baltimore, MD (USA) at 12/12/2025 11:10:00 PM to Exxon Gas Station, Florence, SC (USA) arriving at 12/13/2025 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 8h 50m

Did you know that if you travel from Baltimore, MD to Florence, SC via Raleigh, NC, you can save more than $15? You can find the corresponding connections below.
- FlixBus
  
  10h 10m
  
  0
  
  1:35 AM
  
  Baltimore, MD
  Downtown Bus Station
  
  7:45 AM
  
  Raleigh, NC
  New Bern Ave
  
  0
  
  Economy
  
  $49
  
  A Bus from FlixBus goes from Downtown Bus Station, Baltimore, MD (USA) at 12/13/2025 1:35:00 AM to New Bern Ave, Raleigh, NC (USA) arriving at 12/13/2025 7:45:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 6h 10m
- FlixBus
  
  2h 50m
  
  0
  
  8:55 AM
  
  Raleigh, NC
  Greyhound Bus Station
  
  11:45 AM
  
  Florence, SC
  Bus Station
  
  0
  
  Economy
  
  $30
  
  A Bus from FlixBus goes from Greyhound Bus Station, Raleigh, NC (USA) at 12/13/2025 8:55:00 AM to Bus Station, Florence, SC (USA) arriving at 12/13/2025 11:45:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 2h 50m
Travel time is 1h 20m longer, but you will save $15

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Wanda Coach	8h 50m	11:10 PM	Baltimore, MD	Ponca St	8:00 AM	Florence, SC	Shell Gas Station		Economy	$100	A Bus from Wanda Coach goes from Ponca St, Baltimore, MD (USA) at 12/13/2025 11:10:00 PM to Shell Gas Station, Florence, SC (USA) arriving at 12/14/2025 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 8h 50m

Did you know that if you travel from Baltimore, MD to Florence, SC via Raleigh, NC, you can save more than $22? You can find the corresponding connections below.
- FlixBus
  
  10h 10m
  
  0
  
  1:35 AM
  
  Baltimore, MD
  Downtown Bus Station
  
  7:45 AM
  
  Raleigh, NC
  New Bern Ave
  
  0
  
  Economy
  
  $48
  
  A Bus from FlixBus goes from Downtown Bus Station, Baltimore, MD (USA) at 12/15/2025 1:35:00 AM to New Bern Ave, Raleigh, NC (USA) arriving at 12/15/2025 7:45:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 6h 10m
- FlixBus
  
  2h 50m
  
  0
  
  8:55 AM
  
  Raleigh, NC
  Greyhound Bus Station
  
  11:45 AM
  
  Florence, SC
  Bus Station
  
  0
  
  Economy
  
  $30
  
  A Bus from FlixBus goes from Greyhound Bus Station, Raleigh, NC (USA) at 12/15/2025 8:55:00 AM to Bus Station, Florence, SC (USA) arriving at 12/15/2025 11:45:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 2h 50m
Travel time is 1h 20m longer, but you will save $22

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 0m	11:45 PM	Baltimore, MD	Downtown Bus Station	11:45 AM	Florence, SC	Bus Station	Economy	$89	A Bus from Greyhound US goes from Downtown Bus Station, Baltimore, MD (USA) at 12/14/2025 11:45:00 PM to Bus Station, Florence, SC (USA) arriving at 12/15/2025 11:45:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 12h 0m
FlixBus	10h 10m	1:35 AM	Baltimore, MD	Downtown Bus Station	11:45 AM	Florence, SC	Bus Station	Economy	$90	A Bus from FlixBus goes from Downtown Bus Station, Baltimore, MD (USA) at 12/14/2025 1:35:00 AM to Bus Station, Florence, SC (USA) arriving at 12/14/2025 11:45:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 10h 10m
Wanda Coach	8h 50m	11:10 PM	Baltimore, MD	Focus Travel	8:00 AM	Florence, SC	Exxon Gas Station	Economy	$100	A Bus from Wanda Coach goes from Focus Travel, Baltimore, MD (USA) at 12/14/2025 11:10:00 PM to Exxon Gas Station, Florence, SC (USA) arriving at 12/15/2025 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 8h 50m

Did you know that if you travel from Baltimore, MD to Florence, SC via Raleigh, NC, you can save more than $11? You can find the corresponding connections below.
- FlixBus
  
  10h 10m
  
  0
  
  1:35 AM
  
  Baltimore, MD
  Downtown Bus Station
  
  7:45 AM
  
  Raleigh, NC
  New Bern Ave
  
  0
  
  Economy
  
  $48
  
  A Bus from FlixBus goes from Downtown Bus Station, Baltimore, MD (USA) at 12/15/2025 1:35:00 AM to New Bern Ave, Raleigh, NC (USA) arriving at 12/15/2025 7:45:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 6h 10m
- FlixBus
  
  2h 50m
  
  0
  
  8:55 AM
  
  Raleigh, NC
  Greyhound Bus Station
  
  11:45 AM
  
  Florence, SC
  Bus Station
  
  0
  
  Economy
  
  $30
  
  A Bus from FlixBus goes from Greyhound Bus Station, Raleigh, NC (USA) at 12/15/2025 8:55:00 AM to Bus Station, Florence, SC (USA) arriving at 12/15/2025 11:45:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 2h 50m
Travel time is 1h 20m longer, but you will save $11

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	10h 10m	1:35 AM	Baltimore, MD	Downtown Bus Station	11:45 AM	Florence, SC	Bus Station	Economy	$85	A Bus from FlixBus goes from Downtown Bus Station, Baltimore, MD (USA) at 12/15/2025 1:35:00 AM to Bus Station, Florence, SC (USA) arriving at 12/15/2025 11:45:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 10h 10m
Greyhound US	12h 0m	11:45 PM	Baltimore, MD	Downtown Bus Station	11:45 AM	Florence, SC	Bus Station	Economy	$85	A Bus from Greyhound US goes from Downtown Bus Station, Baltimore, MD (USA) at 12/15/2025 11:45:00 PM to Bus Station, Florence, SC (USA) arriving at 12/16/2025 11:45:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 12h 0m
Wanda Coach	8h 50m	11:10 PM	Baltimore, MD	Ponca St	8:00 AM	Florence, SC	Shell Gas Station	Economy	$100	A Bus from Wanda Coach goes from Ponca St, Baltimore, MD (USA) at 12/15/2025 11:10:00 PM to Shell Gas Station, Florence, SC (USA) arriving at 12/16/2025 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 8h 50m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Wanda Coach	8h 50m	11:10 PM	Baltimore, MD	Ponca St	8:00 AM	Florence, SC	Shell Gas Station	Economy	$100	A Bus from Wanda Coach goes from Ponca St, Baltimore, MD (USA) at 12/18/2025 11:10:00 PM to Shell Gas Station, Florence, SC (USA) arriving at 12/19/2025 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 8h 50m
FlixBus	10h 10m	1:35 AM	Baltimore, MD	Downtown Bus Station	11:45 AM	Florence, SC	Bus Station	Economy	$123	A Bus from FlixBus goes from Downtown Bus Station, Baltimore, MD (USA) at 12/18/2025 1:35:00 AM to Bus Station, Florence, SC (USA) arriving at 12/18/2025 11:45:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 10h 10m
Greyhound US	12h 0m	11:45 PM	Baltimore, MD	Downtown Bus Station	11:45 AM	Florence, SC	Bus Station	Economy	$135	A Bus from Greyhound US goes from Downtown Bus Station, Baltimore, MD (USA) at 12/18/2025 11:45:00 PM to Bus Station, Florence, SC (USA) arriving at 12/19/2025 11:45:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 12h 0m

Did you know that if you travel from Baltimore, MD to Florence, SC via Raleigh, NC, you can save more than $23? You can find the corresponding connections below.
- Busbud
  
  10h 10m
  
  0
  
  1:35 AM
  
  Baltimore, MD
  Downtown Bus Station
  
  7:45 AM
  
  Raleigh, NC
  New Bern Ave
  
  0
  
  Economy
  
  $43
  
  A Bus from Busbud goes from Downtown Bus Station, Baltimore, MD (USA) at 12/18/2025 1:35:00 AM to New Bern Ave, Raleigh, NC (USA) arriving at 12/18/2025 7:45:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 10m
- FlixBus
  
  2h 50m
  
  0
  
  8:55 AM
  
  Raleigh, NC
  Greyhound Bus Station
  
  11:45 AM
  
  Florence, SC
  Bus Station
  
  0
  
  Economy
  
  $34
  
  A Bus from FlixBus goes from Greyhound Bus Station, Raleigh, NC (USA) at 12/18/2025 8:55:00 AM to Bus Station, Florence, SC (USA) arriving at 12/18/2025 11:45:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 2h 50m
Travel time is 1h 20m longer, but you will save $23

Best Price Offer: The price for the cheapest bus from Baltimore, MD to Florence, SC is $66 on 12/14/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Baltimore, MD and Florence, SC

See here how frequent the connections between Baltimore, MD and Florence, SC are, during different times and days of the week.

Monday is the busiest day, with more than 4 daily buses from Baltimore, MD to Florence, SC. Saturday has instead the fewest connections, with only 1 daily coaches between Baltimore, MD and Florence, SC.

The busiest time of the day is the Evening, with 11 buses from Baltimore, MD to Florence, SC, while Night sees the fewest connections between Baltimore, MD and Florence, SC, with 3 offers.

Facts about the bus from Baltimore, MD to Florence, SC

Compare all providers like Wanda Coach, Greyhound US and FlixBus that travel 2 times every day by bus from Baltimore, MD to Florence, SC in one click! Book your bus ticket from Baltimore, MD to Florence, SC starting from $66!

Cheapest Bus	$66
Fastest Bus	8h 50m
Earliest Bus	11:10 PM
Latest Bus	11:45 PM
Daily Bus Routes	2 Ø
Distance	392.9 miles
Bus Companies	Wanda Coach, Greyhound US and FlixBus

Cheapest bus connections from Baltimore, MD to Florence, SC

Every day, 2 buses from 3 bus companies leave Baltimore, MD for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/12/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/07

Monday 12/08

Tuesday 12/09

Wednesday 12/10

Thursday 12/11

Friday 12/12

$68

Saturday 12/13

$100

Sunday 12/14

$66

Monday 12/15

$85

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

$121

Friday 12/19

$100

Saturday 12/20

$103

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

The cheapest time to travel from Baltimore, MD to Florence, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Baltimore, MD to Florence, SC, for the next 30 days.

With a price starting from $66, Sunday is the cheapest day for a bus from Baltimore, MD to Florence, SC. Thursday instead is the most expensive day with prices starting from $100.

Night is the cheapest day time for bus tickets from Baltimore, MD to Florence, SC, with $66. Evening is the most expensive time of the day with prices starting from $85.

How to save money travelling from Baltimore, MD to Florence, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Baltimore, MD to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Baltimore, MD to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Baltimore, MD to Florence, SC are also emptier.

All bus stations and stops in Baltimore, MD and Florence, SC

In the map below, you can see where to find all bus stations in Baltimore, MD and Florence, SC.

Maryland Ave

Maryland Ave & I-83

White Marsh Mall

Perry Hall Blvd 8200

O'Donnell St Cut Off

O'Donnell Street Cut Off 5501

Downtown Bus Station

Haines Street 2110

Bus Stop

Bus Station

S Irby St 611

TA Travel Center

W Lucas St 2301

Exxon Gas Station

W Lucas Street 1901

McDonalds

W. Lucas St. 1908

Shell Gas Station

W Lucas Street 1832

Service and Comfort on the bus from Baltimore, MD to Florence, SC

Want to know which seat classes are available on the buses from Baltimore, MD to Florence, SC? Or which bus companies serve the route Baltimore, MD to Florence, SC? Below you will find answers to your questions.

FAQs about the Baltimore, MD to Florence, SC bus

How much does a Baltimore, MD Florence, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $66 and takes 10h 10m to reach Florence, SC. Compare offers to save money!

How much could I save by comparing buses from Baltimore, MD to Florence, SC?

This route is offered by 3 companies with a range of ticket prices between $66 and $135. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.

On average, how many connections are available from Baltimore, MD to Florence, SC each day?

Every day, the Baltimore, MD to Florence, SC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Baltimore, MD to Florence, SC take?

The fastest bus from Baltimore, MD to Florence, SC is offered by Wanda Coach and takes 8h 50m. Bus tickets for this connection cost $100. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Baltimore, MD to Florence, SC?

The earliest bus arriving in Florence, SC from Baltimore, MD starts at 11:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Baltimore, MD to Florence, SC?

The latest bus trip departing from Baltimore, MD for Florence, SC starts at 11:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Baltimore, MD Florence, SC route?

When traveling by bus from Baltimore, MD to Florence, SC, passengers can travel with Wanda Coach, Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Baltimore, MD and Florence, SC?

You can check all the direct connections between Baltimore, MD and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Wanda Coach, Greyhound US and FlixBus.

What can I take with me on the Baltimore, MD to Florence, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Baltimore, MD Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Baltimore, MD Florence, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Baltimore, MD to Florence, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Baltimore, MD to Florence, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Baltimore, MD and Florence, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Baltimore, MD to Florence, SC?

Prices and availability for 2 trips between Baltimore, MD and Florence, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Baltimore, MD to Florence, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Baltimore, MD and to Florence, SC

Here’s an overview of the most popular bus routes to Baltimore, MD and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!