Compare all timetables for the bus from Chicago to Florence, SC
Here is a selection of the cheapest bus trips from the schedule from Chicago to Florence, SC from various bus operators like Greyhound US or FlixBus for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 26h 30m | 10:00 AM | Chicago | Union Station | 1:30 PM | Florence, SC | Bus Station | Economy | $118 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/8/2025 10:00:00 AM to Bus Station, Florence, SC (USA) arriving at 12/9/2025 1:30:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 26h 30m
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| Greyhound US | 23h 45m | 2:45 PM | Chicago | Downtown Bus Station | 3:30 PM | Florence, SC | Bus Station | Economy | $118 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/8/2025 2:45:00 PM to Bus Station, Florence, SC (USA) arriving at 12/9/2025 3:30:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 23h 45m
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| FlixBus | 23h 30m | 1:00 PM | Chicago | Downtown Bus Station | 1:30 PM | Florence, SC | Bus Station | Economy | $120 |
A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/8/2025 1:00:00 PM to Bus Station, Florence, SC (USA) arriving at 12/9/2025 1:30:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 23h 30m
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| Greyhound US | 36h 45m | 10:00 PM | Chicago | Union Station | 11:45 AM | Florence, SC | Bus Station | Economy | $131 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/8/2025 10:00:00 PM to Bus Station, Florence, SC (USA) arriving at 12/10/2025 11:45:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 36h 45m
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Best Price Offer: The price for the cheapest bus from Chicago to Florence, SC is $118 on 12/8/2025. Flexible travelers save on ticket prices.
Facts about the bus from Chicago to Florence, SC
Compare all providers like Greyhound US and FlixBus that travel 4 times every day by bus from Chicago to Florence, SC in one click! Book your bus ticket from Chicago to Florence, SC starting from $118!
| Cheapest Bus | $118 |
| Fastest Bus | 24h 30m |
| Earliest Bus | 10:00 AM |
| Latest Bus | 10:00 PM |
| Daily Bus Routes | 4 Ø |
| Distance | 681.8 miles |
| Bus Companies | Greyhound US and FlixBus |
Cheapest bus connections from Chicago to Florence, SC
Every day, 4 buses from 2 bus companies leave Chicago for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/06/2025 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
11/30
Monday
12/01
Tuesday
12/02
Wednesday
12/03
Thursday
12/04
Friday
12/05
Saturday
12/06
Sunday
12/07
Monday
12/08
$118
Tuesday
12/09
Wednesday
12/10
Thursday
12/11
Friday
12/12
Saturday
12/13
$151
Sunday
12/14
Monday
12/15
Tuesday
12/16
Wednesday
12/17
Thursday
12/18
Friday
12/19
Saturday
12/20
Sunday
12/21
Monday
12/22
Tuesday
12/23
Wednesday
12/24
Thursday
12/25
Friday
12/26
Saturday
12/27
How to save money travelling from Chicago to Florence, SC
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Chicago to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Florence, SC are also emptier.All bus stations and stops in Chicago and Florence, SC
In the map below, you can see where to find all bus stations in Chicago and Florence, SC.
Service and Comfort on the bus from Chicago to Florence, SC
Want to know which seat classes are available on the buses from Chicago to Florence, SC? Or which bus companies serve the route Chicago to Florence, SC? Below you will find answers to your questions.
FAQs about the Chicago to Florence, SC bus
How much does a Chicago Florence, SC bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $118 and takes 24h 45m to reach Florence, SC. Compare offers to save money!
How much could I save by comparing buses from Chicago to Florence, SC?
This route is offered by 2 companies with a range of ticket prices between $118 and $131. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.
On average, how many connections are available from Chicago to Florence, SC each day?
Every day, the Chicago to Florence, SC bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Chicago to Florence, SC take?
The fastest bus from Chicago to Florence, SC is offered by FlixBus and takes 24h 30m. Bus tickets for this connection cost $120. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Chicago to Florence, SC?
The earliest bus arriving in Florence, SC from Chicago starts at 10:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Chicago to Florence, SC?
The latest bus trip departing from Chicago for Florence, SC starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Chicago Florence, SC route?
When traveling by bus from Chicago to Florence, SC, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Chicago and Florence, SC?
You can check all the direct connections between Chicago and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.
What can I take with me on the Chicago to Florence, SC bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Chicago Florence, SC bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to Florence, SC on your planned travel date.
Available seat classes which are offered on the bus route Chicago to Florence, SC
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Chicago and to Florence, SC
Here’s an overview of the most popular bus routes to Chicago and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Chicago
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- Bus to Chicago from Des Moines, IA
- Bus Durango, DG - Chicago
- Buses from El Paso, TX to Chicago
- Buses Holland, MI to Chicago
- Bus from Indianapolis to Chicago
- Buses Iowa City, IA to Chicago
- Bus from Kalamazoo, MI to Chicago
- Bus Lansing, MI - Chicago
- Bus from Madison, WI to Chicago
- Bus Matamoros to Chicago
- Bus Milwaukee - Chicago
- Bus from New York to Chicago
- Bus Orlando, FL to Chicago
- From Reynosa to Chicago bus
- Buses Toledo, OH to Chicago
- Buses from Tucson, AZ to Chicago
- Washington, DC to Chicago bus
- Bus Routes to Florence, SC
- Buses from Atlanta, GA to Florence, SC
- Bus Baltimore, MD - Florence, SC
- Bus Bridgeport, CT to Florence, SC
- Buses from Charleston, SC to Florence, SC
- Buses College Park, MD - Florence, SC
- Buses Columbia, SC - Florence, SC
- Buses from Columbus, GA to Florence, SC
- Buses to Florence, SC from Dallas
- Buses Gary, IN - Florence, SC
- Bus Lewiston, ME to Florence, SC
- Buses from Madison, WI to Florence, SC
- Buses Newark - Florence, SC
- Bus from Orlando, FL to Florence, SC
- Bus Philadelphia to Florence, SC
- Buses from Providence, RI to Florence, SC
- Buses Raleigh, NC to Florence, SC
- Bus to Florence, SC from Richmond, VA
Popular Airport Shuttles to Chicago and to Florence, SC
