Bus San Antonio, TX to Chicago: Compare prices and save money

Compare all timetables for the bus from San Antonio, TX to Chicago

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to Chicago from various bus operators like FlixBus, Greyhound Lines Mexico or Greyhound US for the next days.

today

$184

tomorrow

$204

Saturday

Sunday

$204

Monday

Tuesday

$189

Wednesday

$194

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	30h 55m	9:15 PM	San Antonio, TX	Bus Station	4:10 AM	Chicago	Downtown Bus Station	Economy	$184	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/18/2025 9:15:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/20/2025 4:10:00 AM. 50 Economy ticket for $184 per person are available. Travel duration is 30h 55m
Greyhound US	31h 35m	12:35 PM	San Antonio, TX	Bus Station	8:10 PM	Chicago	Downtown Bus Station	Economy	$212	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/18/2025 12:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/19/2025 8:10:00 PM. 50 Economy ticket for $212 per person are available. Travel duration is 31h 35m
FlixBus	34h 45m	9:15 PM	San Antonio, TX	Bus Station	8:00 AM	Chicago	Union Station	Economy	$224	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/18/2025 9:15:00 PM to Union Station, Chicago (USA) arriving at 12/20/2025 8:00:00 AM. 50 Economy ticket for $224 per person are available. Travel duration is 34h 45m
FlixBus	32h 5m	9:15 PM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$232	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/18/2025 9:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/20/2025 5:20:00 AM. 50 Economy ticket for $232 per person are available. Travel duration is 32h 5m
Greyhound US	34h 25m	12:35 PM	San Antonio, TX	Bus Station	11:00 PM	Chicago	95th Red Line Station	Economy	$259	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/18/2025 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/19/2025 11:00:00 PM. 50 Economy ticket for $259 per person are available. Travel duration is 34h 25m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	30h 55m	9:15 PM	San Antonio, TX	Bus Station	4:10 AM	Chicago	Downtown Bus Station	Economy	$204	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/19/2025 9:15:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/21/2025 4:10:00 AM. 50 Economy ticket for $204 per person are available. Travel duration is 30h 55m
Greyhound Lines Mexico	33h 10m	6:05 AM	San Antonio, TX	Bus Station	3:15 PM	Chicago	Downtown Bus Station	Economy	$217	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 12/19/2025 6:05:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/20/2025 3:15:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 33h 10m
Greyhound Lines Mexico	26h 40m	1:30 AM	San Antonio, TX	Bus Station	4:10 AM	Chicago	Downtown Bus Station	Economy	$219	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 12/19/2025 1:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/20/2025 4:10:00 AM. 50 Economy ticket for $219 per person are available. Travel duration is 26h 40m
FlixBus	33h 0m	7:30 AM	San Antonio, TX	Bus Station	4:30 PM	Chicago	Downtown Bus Station	Economy	$219	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/19/2025 7:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/20/2025 4:30:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 33h 0m
Greyhound US	31h 35m	12:35 PM	San Antonio, TX	Bus Station	8:10 PM	Chicago	Downtown Bus Station	Economy	$231	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/19/2025 12:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/20/2025 8:10:00 PM. 50 Economy ticket for $231 per person are available. Travel duration is 31h 35m

Did you know that if you travel from San Antonio, TX to Chicago via Dallas, you can save more than $29? You can find the corresponding connections below.
- FlixBus
  
  31h 30m
  
  0
  
  7:45 AM
  
  San Antonio, TX
  Pearl District
  
  1:20 PM
  
  Dallas
  East Transfer Center
  
  0
  
  Economy
  
  $47
  
  A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 12/19/2025 7:45:00 AM to East Transfer Center, Dallas (USA) arriving at 12/19/2025 1:20:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 5h 35m
- Busbud
  
  25h 0m
  
  0
  
  2:15 PM
  
  Dallas
  Bus Station
  
  3:15 PM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $128
  
  A Bus from Busbud goes from Bus Station, Dallas (USA) at 12/19/2025 2:15:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/20/2025 3:15:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 25h 0m
Travel time is 4h 50m longer, but you will save $29

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	31h 35m	12:35 PM	San Antonio, TX	Bus Station	8:10 PM	Chicago	Downtown Bus Station	Economy	$204	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/21/2025 12:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/22/2025 8:10:00 PM. 50 Economy ticket for $204 per person are available. Travel duration is 31h 35m
FlixBus	33h 0m	7:30 AM	San Antonio, TX	Bus Station	4:30 PM	Chicago	Downtown Bus Station	Economy	$211	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/21/2025 7:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/22/2025 4:30:00 PM. 50 Economy ticket for $211 per person are available. Travel duration is 33h 0m
FlixBus	32h 45m	7:45 AM	San Antonio, TX	Pearl District	4:30 PM	Chicago	Downtown Bus Station	Economy	$211	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 12/21/2025 7:45:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/22/2025 4:30:00 PM. 50 Economy ticket for $211 per person are available. Travel duration is 32h 45m
Greyhound Lines Mexico	33h 10m	6:05 AM	San Antonio, TX	Bus Station	3:15 PM	Chicago	Downtown Bus Station	Economy	$223	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 12/21/2025 6:05:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/22/2025 3:15:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 33h 10m
Greyhound US	34h 25m	12:35 PM	San Antonio, TX	Bus Station	11:00 PM	Chicago	95th Red Line Station	Economy	$234	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/21/2025 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/22/2025 11:00:00 PM. 50 Economy ticket for $234 per person are available. Travel duration is 34h 25m

Did you know that if you travel from San Antonio, TX to Chicago via Dallas, you can save more than $29? You can find the corresponding connections below.
- FlixBus
  
  31h 30m
  
  0
  
  7:45 AM
  
  San Antonio, TX
  Pearl District
  
  1:20 PM
  
  Dallas
  East Transfer Center
  
  0
  
  Economy
  
  $47
  
  A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 12/19/2025 7:45:00 AM to East Transfer Center, Dallas (USA) arriving at 12/19/2025 1:20:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 5h 35m
- Busbud
  
  25h 0m
  
  0
  
  2:15 PM
  
  Dallas
  Bus Station
  
  3:15 PM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $128
  
  A Bus from Busbud goes from Bus Station, Dallas (USA) at 12/19/2025 2:15:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/20/2025 3:15:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 25h 0m
Travel Time is 0h 5m shorter, and you will save $29

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	36h 45m	7:15 PM	San Antonio, TX	Bus Station	8:00 AM	Chicago	Union Station	Economy	$189	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 12/23/2025 7:15:00 PM to Union Station, Chicago (USA) arriving at 12/25/2025 8:00:00 AM. 50 Economy ticket for $189 per person are available. Travel duration is 36h 45m
Greyhound Lines Mexico	32h 55m	7:15 PM	San Antonio, TX	Bus Station	4:10 AM	Chicago	Downtown Bus Station	Economy	$189	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 12/23/2025 7:15:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/25/2025 4:10:00 AM. 50 Economy ticket for $189 per person are available. Travel duration is 32h 55m
Greyhound US	31h 35m	12:35 PM	San Antonio, TX	Bus Station	8:10 PM	Chicago	Downtown Bus Station	Economy	$190	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/23/2025 12:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/24/2025 8:10:00 PM. 50 Economy ticket for $190 per person are available. Travel duration is 31h 35m
Greyhound US	34h 25m	12:35 PM	San Antonio, TX	Bus Station	11:00 PM	Chicago	95th Red Line Station	Economy	$213	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/23/2025 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/24/2025 11:00:00 PM. 50 Economy ticket for $213 per person are available. Travel duration is 34h 25m
Greyhound Lines Mexico	34h 5m	7:15 PM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$218	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 12/23/2025 7:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/25/2025 5:20:00 AM. 50 Economy ticket for $218 per person are available. Travel duration is 34h 5m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	31h 35m	12:35 PM	San Antonio, TX	Bus Station	8:10 PM	Chicago	Downtown Bus Station	Economy	$194	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/24/2025 12:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/25/2025 8:10:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 31h 35m
FlixBus	30h 55m	9:15 PM	San Antonio, TX	Bus Station	4:10 AM	Chicago	Downtown Bus Station	Economy	$195	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/24/2025 9:15:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/26/2025 4:10:00 AM. 50 Economy ticket for $195 per person are available. Travel duration is 30h 55m
Greyhound Lines Mexico	30h 30m	1:30 AM	San Antonio, TX	Bus Station	8:00 AM	Chicago	Union Station	Economy	$198	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 12/24/2025 1:30:00 AM to Union Station, Chicago (USA) arriving at 12/25/2025 8:00:00 AM. 50 Economy ticket for $198 per person are available. Travel duration is 30h 30m
FlixBus	51h 45m	7:45 AM	San Antonio, TX	Pearl District	11:30 AM	Chicago	Downtown Bus Station	Economy	$198	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 12/24/2025 7:45:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/26/2025 11:30:00 AM. 50 Economy ticket for $198 per person are available. Travel duration is 51h 45m
Greyhound Lines Mexico	26h 40m	1:30 AM	San Antonio, TX	Bus Station	4:10 AM	Chicago	Downtown Bus Station	Economy	$201	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 12/24/2025 1:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/25/2025 4:10:00 AM. 50 Economy ticket for $201 per person are available. Travel duration is 26h 40m

Did you know that if you travel from San Antonio, TX to Chicago via Dallas, you can save more than $19? You can find the corresponding connections below.
- FlixBus
  
  31h 30m
  
  0
  
  7:45 AM
  
  San Antonio, TX
  Pearl District
  
  1:20 PM
  
  Dallas
  East Transfer Center
  
  0
  
  Economy
  
  $47
  
  A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 12/19/2025 7:45:00 AM to East Transfer Center, Dallas (USA) arriving at 12/19/2025 1:20:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 5h 35m
- Busbud
  
  25h 0m
  
  0
  
  2:15 PM
  
  Dallas
  Bus Station
  
  3:15 PM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $128
  
  A Bus from Busbud goes from Bus Station, Dallas (USA) at 12/19/2025 2:15:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/20/2025 3:15:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 25h 0m
Travel time is 4h 50m longer, but you will save $19

Best Price Offer: The price for the cheapest bus from San Antonio, TX to Chicago is $138 on 1/4/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Antonio, TX and Chicago

See here how frequent the connections between San Antonio, TX and Chicago are, during different times and days of the week.

Sunday is the busiest day, with more than 14 daily buses from San Antonio, TX to Chicago. Thursday has instead the fewest connections, with only 5 daily coaches between San Antonio, TX and Chicago.

The busiest time of the day is the Morning, with 15 buses from San Antonio, TX to Chicago, while Afternoon sees the fewest connections between San Antonio, TX and Chicago, with 9 offers.

Facts about the bus from San Antonio, TX to Chicago

Compare all providers like FlixBus, Greyhound Lines Mexico and Greyhound US that travel 9 times every day by bus from San Antonio, TX to Chicago in one click! Book your bus ticket from San Antonio, TX to Chicago starting from $138!

Cheapest Bus	$138
Fastest Bus	26h 40m
Earliest Bus	12:35 PM
Latest Bus	9:15 PM
Daily Bus Routes	9 Ø
Distance	1,052.2 miles
Bus Companies	FlixBus, Greyhound Lines Mexico and Greyhound US

Cheapest bus connections from San Antonio, TX to Chicago

Every day, 9 buses from 3 bus companies leave San Antonio, TX for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/18/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

$232

Friday 12/19

$204

Saturday 12/20

Sunday 12/21

$234

Monday 12/22

Tuesday 12/23

$189

Wednesday 12/24

$194

Thursday 12/25

Friday 12/26

$220

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

$138

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from San Antonio, TX to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to Chicago, for the next 30 days.

With a price starting from $138, Sunday is the cheapest day for a bus from San Antonio, TX to Chicago. Friday instead is the most expensive day with prices starting from $204.

Night is the cheapest day time for bus tickets from San Antonio, TX to Chicago, with $138. Morning is the most expensive time of the day with prices starting from $198.

How to save money travelling from San Antonio, TX to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to Chicago are also emptier.

All bus stations and stops in San Antonio, TX and Chicago

In the map below, you can see where to find all bus stations in San Antonio, TX and Chicago.

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

W. Southcross & Buffalo Bus Stop

Commerce & Bowie Bus Stop

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from San Antonio, TX to Chicago? Compare all modes of transports from San Antonio, TX to Chicago.

Service and Comfort on the bus from San Antonio, TX to Chicago

Want to know which seat classes are available on the buses from San Antonio, TX to Chicago? Or which bus companies serve the route San Antonio, TX to Chicago? Below you will find answers to your questions.

FAQs about the San Antonio, TX to Chicago bus

How much does a San Antonio, TX Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $138 and takes 30h 55m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to Chicago?

This route is offered by 3 companies with a range of ticket prices between $138 and $315. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from San Antonio, TX to Chicago each day?

Every day, the San Antonio, TX to Chicago bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to Chicago take?

The fastest bus from San Antonio, TX to Chicago is offered by Greyhound Lines Mexico and takes 26h 40m. Bus tickets for this connection cost $219. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to Chicago?

The earliest bus arriving in Chicago from San Antonio, TX starts at 12:35 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to Chicago?

The latest bus trip departing from San Antonio, TX for Chicago starts at 9:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX Chicago route?

When traveling by bus from San Antonio, TX to Chicago, passengers can travel with FlixBus, Greyhound Lines Mexico and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and Chicago?

You can check all the direct connections between San Antonio, TX and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound Lines Mexico and Greyhound US.

What can I take with me on the San Antonio, TX to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from San Antonio, TX to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between San Antonio, TX and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Antonio, TX to Chicago?

Prices and availability for 9 trips between San Antonio, TX and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Antonio, TX to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to Chicago

Here’s an overview of the most popular bus routes to San Antonio, TX and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!