Bus from San Antonio, TX to Chicago from $106

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Compare all timetables for the bus from San Antonio, TX to Chicago

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to Chicago from various bus operators like Greyhound Lines Mexico, Greyhound US or FlixBus for the next days.
today
from $138
tomorrow
from $174
Wednesday
Thursday
from $106
Friday
Saturday
from $166
Sunday
from $209

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    33h 20m
    0
    12:40 PM
    San Antonio, TX
    Bus Station
    10:00 PM
    Chicago
    95th Red Line Station
    0
    Greyhound US
    Economy
    $138
  • Greyhound Lines Mexico
    33h 10m
    0
    6:05 AM
    San Antonio, TX
    Bus Station
    3:15 PM
    Chicago
    Downtown Bus Station
    0
    Greyhound Lines Mexico
    Economy
    $139
  • FlixBus
    51h 20m
    0
    7:45 AM
    San Antonio, TX
    Pearl District
    11:05 AM
    Chicago
    95th Red Line Station
    0
    FlixBus
    Economy
    $139
  • Greyhound Lines Mexico
    26h 10m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    3:40 AM
    Chicago
    Downtown Bus Station
    0
    Greyhound Lines Mexico
    Economy
    $140
  • Greyhound US
    31h 30m
    0
    12:40 PM
    San Antonio, TX
    Bus Station
    8:10 PM
    Chicago
    Downtown Bus Station
    0
    Greyhound US
    Economy
    $140

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound Lines Mexico
    37h 5m
    0
    7:15 PM
    San Antonio, TX
    Bus Station
    8:20 AM
    Chicago
    95th Red Line Station
    0
    Greyhound Lines Mexico
    Economy
    $174
  • Greyhound US
    33h 20m
    0
    12:40 PM
    San Antonio, TX
    Bus Station
    10:00 PM
    Chicago
    95th Red Line Station
    0
    Greyhound US
    Economy
    $179
  • Greyhound Lines Mexico
    30h 50m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    8:20 AM
    Chicago
    95th Red Line Station
    0
    Greyhound Lines Mexico
    Economy
    $210
  • Greyhound Lines Mexico
    36h 30m
    0
    6:05 AM
    San Antonio, TX
    Bus Station
    6:35 PM
    Chicago
    95th Red Line Station
    0
    Greyhound Lines Mexico
    Economy
    $226
  • Did you know that if you travel from San Antonio, TX to Chicago via Austin, you can save more than $54? You can find the corresponding connections below.
    • Busbud
      30h 40m
      0
      9:00 PM
      San Antonio, TX
      Bus Station
      10:40 PM
      Austin
      5119 Eastside Bus Plaza
      0
      Busbud
      Economy
      $13
      • Waiting Time 0h 10m
    • Busbud
      28h 50m
      0
      10:50 PM
      Austin
      5119 Eastside Bus Plaza
      3:40 AM
      Chicago
      Downtown Bus Station
      0
      Busbud
      Economy
      $107
    Travel Time is 0h 10m shorter, and you will save $54

Cheapest bus trips Thursday

Prices are for one way and one person
  • Greyhound US
    31h 50m
    0
    12:40 PM
    San Antonio, TX
    Bus Station
    8:30 PM
    Chicago
    95th Red Line Station
    0
    Greyhound US
    Economy
    $106
  • Greyhound Lines Mexico
    36h 30m
    0
    6:05 AM
    San Antonio, TX
    Bus Station
    6:35 PM
    Chicago
    95th Red Line Station
    0
    Greyhound Lines Mexico
    Economy
    $108
  • FlixBus
    51h 5m
    0
    7:45 AM
    San Antonio, TX
    Pearl District
    10:50 AM
    Chicago
    95th Red Line Station
    0
    FlixBus
    Economy
    $114
  • Greyhound Lines Mexico
    30h 50m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    8:20 AM
    Chicago
    95th Red Line Station
    0
    Greyhound Lines Mexico
    Economy
    $115
  • Greyhound US
    31h 30m
    0
    12:40 PM
    San Antonio, TX
    Bus Station
    8:10 PM
    Chicago
    Downtown Bus Station
    0
    Greyhound US
    Economy
    $119

Cheapest bus trips Saturday

Prices are for one way and one person
  • Greyhound Lines Mexico
    36h 30m
    0
    6:05 AM
    San Antonio, TX
    Bus Station
    6:35 PM
    Chicago
    95th Red Line Station
    0
    Greyhound Lines Mexico
    Economy
    $166
  • Greyhound Lines Mexico
    36h 30m
    0
    6:05 AM
    San Antonio, TX
    Bus Station
    6:35 PM
    Chicago
    95th Red Line Station
    0
    Greyhound Lines Mexico
    Economy
    $166
  • FlixBus
    35h 20m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    8:20 AM
    Chicago
    95th Red Line Station
    0
    FlixBus
    Economy
    $166
  • FlixBus
    30h 40m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    3:40 AM
    Chicago
    Downtown Bus Station
    0
    FlixBus
    Economy
    $184
  • Greyhound US
    33h 20m
    0
    12:40 PM
    San Antonio, TX
    Bus Station
    10:00 PM
    Chicago
    95th Red Line Station
    0
    Greyhound US
    Economy
    $188
  • Did you know that if you travel from San Antonio, TX to Chicago via Austin, you can save more than $46? You can find the corresponding connections below.
    • Busbud
      30h 40m
      0
      9:00 PM
      San Antonio, TX
      Bus Station
      10:40 PM
      Austin
      5119 Eastside Bus Plaza
      0
      Busbud
      Economy
      $13
      • Waiting Time 0h 10m
    • Busbud
      28h 50m
      0
      10:50 PM
      Austin
      5119 Eastside Bus Plaza
      3:40 AM
      Chicago
      Downtown Bus Station
      0
      Busbud
      Economy
      $107
    Travel time is the same as the direct connection, but you will save $46

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    35h 20m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    8:20 AM
    Chicago
    95th Red Line Station
    0
    FlixBus
    Economy
    $209
  • Greyhound Lines Mexico
    30h 50m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    8:20 AM
    Chicago
    95th Red Line Station
    0
    Greyhound Lines Mexico
    Economy
    $223
  • Greyhound Lines Mexico
    36h 30m
    0
    6:05 AM
    San Antonio, TX
    Bus Station
    6:35 PM
    Chicago
    95th Red Line Station
    0
    Greyhound Lines Mexico
    Economy
    $231
  • Greyhound US
    33h 20m
    0
    12:40 PM
    San Antonio, TX
    Bus Station
    10:00 PM
    Chicago
    95th Red Line Station
    0
    Greyhound US
    Economy
    $260
  • FlixBus
    51h 20m
    0
    7:45 AM
    San Antonio, TX
    Pearl District
    11:05 AM
    Chicago
    95th Red Line Station
    0
    FlixBus
    Economy
    $260
  • Did you know that if you travel from San Antonio, TX to Chicago via Austin, you can save more than $89? You can find the corresponding connections below.
    • Busbud
      30h 40m
      0
      9:00 PM
      San Antonio, TX
      Bus Station
      10:40 PM
      Austin
      5119 Eastside Bus Plaza
      0
      Busbud
      Economy
      $13
      • Waiting Time 0h 10m
    • Busbud
      28h 50m
      0
      10:50 PM
      Austin
      5119 Eastside Bus Plaza
      3:40 AM
      Chicago
      Downtown Bus Station
      0
      Busbud
      Economy
      $107
    Travel Time is 0h 10m shorter, and you will save $89

Frequency of bus connections between San Antonio, TX and Chicago

See here how frequent the connections between San Antonio, TX and Chicago are, during different times and days of the week.
Monday is the busiest day, with more than 26 daily buses from San Antonio, TX to Chicago. Tuesday has instead the fewest connections, with only 4 daily coaches between San Antonio, TX and Chicago.
The busiest time of the day is the Morning, with 25 buses from San Antonio, TX to Chicago, while Evening sees the fewest connections between San Antonio, TX and Chicago, with 13 offers.

Facts about the bus from San Antonio, TX to Chicago

Compare all providers like Greyhound Lines Mexico, Greyhound US and FlixBus that travel 14 times every day by bus from San Antonio, TX to Chicago in one click! Book your bus ticket from San Antonio, TX to Chicago starting from $106!

Cheapest Bus $106
Fastest Bus 22h 45m
Earliest Bus 1:30 AM
Latest Bus 9:00 PM
Daily Bus Routes 14 Ø
Distance 1,052.2 miles
Bus Companies Greyhound Lines Mexico, Greyhound US, FlixBus and Tornado Bus Company

Cheapest bus connections from San Antonio, TX to Chicago

Every day, 14 buses from 4 bus companies leave San Antonio, TX for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/19/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/18
Monday 05/19
$138
Tuesday 05/20
$174
Wednesday 05/21
Thursday 05/22
$157
Friday 05/23
Saturday 05/24
$165
Sunday 05/25
$209
Monday 05/26
$126
Tuesday 05/27
$110
Wednesday 05/28
Thursday 05/29
Friday 05/30
$121
Saturday 05/31
Sunday 06/01
$117
Monday 06/02
Tuesday 06/03
Wednesday 06/04
Thursday 06/05
Friday 06/06
Saturday 06/07
$95
Sunday 06/08
Monday 06/09
Tuesday 06/10
Wednesday 06/11
Thursday 06/12
Friday 06/13
Saturday 06/14

The cheapest time to travel from San Antonio, TX to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to Chicago, for the next 30 days.
With a price starting from $106, Thursday is the cheapest day for a bus from San Antonio, TX to Chicago. Sunday instead is the most expensive day with prices starting from $209.
Afternoon is the cheapest day time for bus tickets from San Antonio, TX to Chicago, with $106. Evening is the most expensive time of the day with prices starting from $140.

How to save money travelling from San Antonio, TX to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to Chicago are also emptier.

Beloved bus companies from San Antonio, TX to Chicago

These are the most booked bus companies between San Antonio, TX to Chicago from our users.

Greyhound Lines Mexico from San Antonio, TX to Chicago

Greyhound Lines Mexico

Here you will find the key facts about the Greyhound Lines Mexico bus route San Antonio, TX to Chicago:

Cheapest Price $108
Fastest Bus 26h 10m
Earliest Bus 1:30 AM
Last Bus 6:05 AM
Daily Connections 8 Ø
Found on 5/17/2025

Greyhound US from San Antonio, TX to Chicago

Greyhound US

Here you will find the key facts about the Greyhound US bus route San Antonio, TX to Chicago:

Cheapest Price $106
Fastest Bus 31h 30m
Earliest Bus 12:40 PM
Last Bus 12:40 PM
Daily Connections 2 Ø
Found on 5/17/2025

All bus stations and stops in San Antonio, TX and Chicago

In the map below, you can see where to find all bus stations in San Antonio, TX and Chicago.

Service and Comfort on the bus from San Antonio, TX to Chicago

Want to know which seat classes are available on the buses from San Antonio, TX to Chicago? Or which bus companies serve the route San Antonio, TX to Chicago? Below you will find answers to your questions.

FAQs about the San Antonio, TX to Chicago bus

How much does a San Antonio, TX Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $106 and takes 31h 50m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to Chicago?

This route is offered by 4 companies with a range of ticket prices between $106 and $287. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from San Antonio, TX to Chicago each day?

Every day, the San Antonio, TX to Chicago bus route is served by approximately 14 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to Chicago take?

The fastest bus from San Antonio, TX to Chicago is offered by Tornado Bus Company and takes 22h 45m. Bus tickets for this connection cost $240. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to Chicago?

The earliest bus arriving in Chicago from San Antonio, TX starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to Chicago?

The latest bus trip departing from San Antonio, TX for Chicago starts at 9:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX Chicago route?

When traveling by bus from San Antonio, TX to Chicago, passengers can travel with Greyhound Lines Mexico, Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and Chicago?

You can check all the direct connections between San Antonio, TX and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound Lines Mexico, Greyhound US and FlixBus.

What can I take with me on the San Antonio, TX to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to Chicago on your planned travel date.

Available seat classes which are offered on the bus route San Antonio, TX to Chicago

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to Chicago

Here’s an overview of the most popular bus routes to San Antonio, TX and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Monterrey, NL - San Antonio, TX Bus Monterrey, NL - San Antonio, TX
Bus to San Antonio, TX from Waco, TX Bus to San Antonio, TX from Waco, TX
Buses Mexico City - San Antonio, TX Buses Mexico City - San Antonio, TX
From Odessa, TX to San Antonio, TX bus From Odessa, TX to San Antonio, TX bus
Buses South Bend, IN - Chicago Buses South Bend, IN - Chicago
From Columbus, OH to Chicago bus From Columbus, OH to Chicago bus
Buses Dallas - Chicago Buses Dallas - Chicago
Buses Iowa City, IA to Chicago Buses Iowa City, IA to Chicago
Popular Airport Shuttles to San Antonio, TX and to Chicago
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