Bus San Antonio, TX to Chicago: Compare prices and save money

Compare all timetables for the bus from San Antonio, TX to Chicago

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to Chicago from various bus operators like FlixBus, Greyhound Lines Mexico or Greyhound US for the next days.

today

tomorrow

$155

Saturday

$156

Sunday

Monday

$187

Tuesday

Wednesday

$153

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	26h 40m	1:30 AM	San Antonio, TX	Bus Station	4:10 AM	Chicago	Downtown Bus Station	Economy	$155	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 12/5/2025 1:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/6/2025 4:10:00 AM. 50 Economy ticket for $155 per person are available. Travel duration is 26h 40m
Greyhound Lines Mexico	33h 10m	6:05 AM	San Antonio, TX	Bus Station	3:15 PM	Chicago	Downtown Bus Station	Economy	$155	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 12/5/2025 6:05:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/6/2025 3:15:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 33h 10m
FlixBus	34h 45m	9:15 PM	San Antonio, TX	Bus Station	8:00 AM	Chicago	Union Station	Economy	$155	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/5/2025 9:15:00 PM to Union Station, Chicago (USA) arriving at 12/7/2025 8:00:00 AM. 50 Economy ticket for $155 per person are available. Travel duration is 34h 45m
FlixBus	30h 55m	9:15 PM	San Antonio, TX	Bus Station	4:10 AM	Chicago	Downtown Bus Station	Economy	$155	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/5/2025 9:15:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/7/2025 4:10:00 AM. 50 Economy ticket for $155 per person are available. Travel duration is 30h 55m
Greyhound US	31h 30m	12:40 PM	San Antonio, TX	Bus Station	8:10 PM	Chicago	Downtown Bus Station	Economy	$156	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/5/2025 12:40:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/6/2025 8:10:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 31h 30m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	27h 50m	1:30 AM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$156	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 12/6/2025 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/7/2025 5:20:00 AM. 50 Economy ticket for $156 per person are available. Travel duration is 27h 50m
Greyhound US	33h 10m	12:40 PM	San Antonio, TX	Bus Station	9:50 PM	Chicago	95th Red Line Station	Economy	$156	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/6/2025 12:40:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/7/2025 9:50:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 33h 10m
FlixBus	32h 25m	7:30 AM	San Antonio, TX	Bus Station	3:55 PM	Chicago	95th Red Line Station	Economy	$158	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 12/6/2025 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/7/2025 3:55:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 32h 25m
FlixBus	32h 10m	7:45 AM	San Antonio, TX	Pearl District	3:55 PM	Chicago	95th Red Line Station	Economy	$158	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 12/6/2025 7:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/7/2025 3:55:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 32h 10m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	27h 50m	1:30 AM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$187	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 12/8/2025 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/9/2025 5:20:00 AM. 50 Economy ticket for $187 per person are available. Travel duration is 27h 50m
Greyhound US	33h 10m	12:40 PM	San Antonio, TX	Bus Station	9:50 PM	Chicago	95th Red Line Station	Economy	$190	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/8/2025 12:40:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/9/2025 9:50:00 PM. 50 Economy ticket for $190 per person are available. Travel duration is 33h 10m
FlixBus	38h 5m	7:45 AM	San Antonio, TX	Pearl District	9:50 PM	Chicago	95th Red Line Station	Economy	$190	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 12/8/2025 7:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/9/2025 9:50:00 PM. 50 Economy ticket for $190 per person are available. Travel duration is 38h 5m

Did you know that if you travel from San Antonio, TX to Chicago via Dallas, you can save more than $42? You can find the corresponding connections below.
- Busbud
  
  34h 50m
  
  0
  
  5:20 PM
  
  San Antonio, TX
  Pearl District
  
  11:05 PM
  
  Dallas
  Downtown
  
  0
  
  Economy
  
  $33
  
  A Bus from Busbud goes from Pearl District, San Antonio, TX (USA) at 12/8/2025 5:20:00 PM to Downtown, Dallas (USA) arriving at 12/8/2025 11:05:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 5h 45m
- Busbud
  
  20h 55m
  
  0
  
  7:15 AM
  
  Dallas
  Bus Station
  
  4:10 AM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $112
  
  A Bus from Busbud goes from Bus Station, Dallas (USA) at 12/9/2025 7:15:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/10/2025 4:10:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 20h 55m
Travel time is 7h 0m longer, but you will save $42

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	32h 5m	9:15 PM	San Antonio, TX	Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$153	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 12/10/2025 9:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/12/2025 5:20:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 32h 5m
FlixBus	51h 20m	7:45 AM	San Antonio, TX	Pearl District	11:05 AM	Chicago	95th Red Line Station	Economy	$155	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 12/10/2025 7:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/12/2025 11:05:00 AM. 50 Economy ticket for $155 per person are available. Travel duration is 51h 20m
Greyhound US	34h 25m	12:35 PM	San Antonio, TX	Bus Station	11:00 PM	Chicago	95th Red Line Station	Economy	$155	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 12/10/2025 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/11/2025 11:00:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 34h 25m
Greyhound Lines Mexico	26h 40m	1:30 AM	San Antonio, TX	Bus Station	4:10 AM	Chicago	Downtown Bus Station	Economy	$171	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 12/10/2025 1:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/11/2025 4:10:00 AM. 50 Economy ticket for $171 per person are available. Travel duration is 26h 40m
Tornado Bus Company	23h 56m	10:45 AM	San Antonio, TX	Tornado Bus Company	10:40 AM	Chicago	California & 35th Street Bus Stop	Basic	$272	A Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 12/10/2025 10:45:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 12/11/2025 10:40:30 AM. 50 Basic ticket for $272 per person are available. Travel duration is 23h 56m

Best Price Offer: The price for the cheapest bus from San Antonio, TX to Chicago is $153 on 12/10/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between San Antonio, TX and Chicago

See here how frequent the connections between San Antonio, TX and Chicago are, during different times and days of the week.

Wednesday is the busiest day, with more than 21 daily buses from San Antonio, TX to Chicago. Monday has instead the fewest connections, with only 3 daily coaches between San Antonio, TX and Chicago.

The busiest time of the day is the Morning, with 15 buses from San Antonio, TX to Chicago, while Afternoon sees the fewest connections between San Antonio, TX and Chicago, with 7 offers.

Facts about the bus from San Antonio, TX to Chicago

Compare all providers like FlixBus, Greyhound Lines Mexico and Greyhound US that travel 9 times every day by bus from San Antonio, TX to Chicago in one click! Book your bus ticket from San Antonio, TX to Chicago starting from $153!

Cheapest Bus	$153
Fastest Bus	23h 35m
Earliest Bus	1:30 AM
Latest Bus	9:15 PM
Daily Bus Routes	9 Ø
Distance	1,052.2 miles
Bus Companies	FlixBus, Greyhound Lines Mexico, Greyhound US, Valley Transit and Tornado Bus Company

Cheapest bus connections from San Antonio, TX to Chicago

Every day, 9 buses from 5 bus companies leave San Antonio, TX for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$155

Saturday 12/06

$156

Sunday 12/07

Monday 12/08

$187

Tuesday 12/09

Wednesday 12/10

$153

Thursday 12/11

$202

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from San Antonio, TX to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to Chicago, for the next 30 days.

With a price starting from $153, Wednesday is the cheapest day for a bus from San Antonio, TX to Chicago. Monday instead is the most expensive day with prices starting from $187.

Evening is the cheapest day time for bus tickets from San Antonio, TX to Chicago, with $153. Afternoon is the most expensive time of the day with prices starting from $155.

How to save money travelling from San Antonio, TX to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to Chicago are also emptier.

Beloved bus companies from San Antonio, TX to Chicago

These are the most booked bus companies between San Antonio, TX to Chicago from our users.

Tornado Bus Company from San Antonio, TX to Chicago

Here you will find the key facts about the Tornado Bus Company bus route San Antonio, TX to Chicago:

Cheapest Price	$272
Fastest Bus	23h 35m
Earliest Bus	10:45 AM
Last Bus	11:05 AM
Daily Connections	2 Ø
Found on	12/2/2025

All bus stations and stops in San Antonio, TX and Chicago

In the map below, you can see where to find all bus stations in San Antonio, TX and Chicago.

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

W. Southcross & Buffalo Bus Stop

Commerce & Bowie Bus Stop

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from San Antonio, TX to Chicago? Compare all modes of transports from San Antonio, TX to Chicago.

Service and Comfort on the bus from San Antonio, TX to Chicago

Want to know which seat classes are available on the buses from San Antonio, TX to Chicago? Or which bus companies serve the route San Antonio, TX to Chicago? Below you will find answers to your questions.

FAQs about the San Antonio, TX to Chicago bus

How much does a San Antonio, TX Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $153 and takes 32h 5m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to Chicago?

This route is offered by 5 companies with a range of ticket prices between $153 and $272. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from San Antonio, TX to Chicago each day?

Every day, the San Antonio, TX to Chicago bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to Chicago take?

The fastest bus from San Antonio, TX to Chicago is offered by Tornado Bus Company and takes 23h 35m. Bus tickets for this connection cost $272. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to Chicago?

The earliest bus arriving in Chicago from San Antonio, TX starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to Chicago?

The latest bus trip departing from San Antonio, TX for Chicago starts at 9:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX Chicago route?

When traveling by bus from San Antonio, TX to Chicago, passengers can travel with FlixBus, Greyhound Lines Mexico and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and Chicago?

You can check all the direct connections between San Antonio, TX and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound Lines Mexico and Greyhound US.

What can I take with me on the San Antonio, TX to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to Chicago on your planned travel date.

Available seat classes which are offered on the bus route San Antonio, TX to Chicago

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to Chicago

Here’s an overview of the most popular bus routes to San Antonio, TX and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!