What is the best way to travel from San Antonio, TX to Chicago?
Looking for a trip? Compare all the available Flights and Buses for the journey to Chicago from San Antonio, TX. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 7 available companies to find your perfect trip!
What is the cheapest way to reach Chicago from San Antonio, TX?
You can get to Chicago with just $106 by taking a Bus from Greyhound Lines Mexico, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 5/2/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/4/2026 5:20:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 31h 25m
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Tornado Bus Company24h 16m011:05 AMSan Antonio, TXTornado Bus Company11:21 AMChicagoCalifornia & 35th Street Bus Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 5/2/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 5/3/2026 11:21:00 AM. 50 Basic ticket for $255 per person are available. Travel duration is 24h 16m
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Tornado Bus Company24h 2m011:05 AMSan Antonio, TXTornado Bus Company11:07 AMChicagoCalifornia & 35th Street Bus Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 5/2/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 5/3/2026 11:07:30 AM. 50 Basic ticket for $255 per person are available. Travel duration is 24h 2m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/2/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/3/2026 11:35:00 PM. 50 Economy ticket for $301 per person are available. Travel duration is 35h 0m
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Frontier Airlines17h 41m04:04 PMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/2/2026 4:04:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/3/2026 9:45:00 AM. 50 Economy ticket for $271 per person are available. Travel duration is 17h 41m
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Spirit Airlines8h 55m02:12 PMSan Antonio AirportSan Antonio Airport11:07 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/2/2026 2:12:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/2/2026 11:07:00 PM. 50 Economy ticket for $308 per person are available. Travel duration is 8h 55m
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United Airlines2h 56m06:49 AMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/2/2026 6:49:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/2/2026 9:45:00 AM. 50 Economy ticket for $477 per person are available. Travel duration is 2h 56m
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Volaris14h 9m08:41 PMSan Antonio AirportSan Antonio Airport10:50 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/2/2026 8:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/3/2026 10:50:00 AM. 50 Economy ticket for $500 per person are available. Travel duration is 14h 9m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 5/2/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/3/2026 5:52:00 AM. 50 Economy ticket for $569 per person are available. Travel duration is 12h 7m
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Spirit Airlines17h 29m02:12 PMSan Antonio AirportSan Antonio Airport7:41 AMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/2/2026 2:12:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/3/2026 7:41:00 AM. 50 Economy ticket for $602 per person are available. Travel duration is 17h 29m
Cheapest Buses Saturday
Cheapest Flights Saturday
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 5/3/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/5/2026 5:20:00 AM. 50 Economy ticket for $196 per person are available. Travel duration is 31h 25m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/3/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/4/2026 5:20:00 AM. 50 Economy ticket for $205 per person are available. Travel duration is 27h 50m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/3/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/4/2026 11:35:00 PM. 50 Economy ticket for $228 per person are available. Travel duration is 35h 0m
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Spirit Airlines8h 55m02:12 PMSan Antonio AirportSan Antonio Airport11:07 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/3/2026 2:12:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/3/2026 11:07:00 PM. 50 Economy ticket for $353 per person are available. Travel duration is 8h 55m
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Frontier Airlines17h 39m012:35 PMSan Antonio AirportSan Antonio Airport6:14 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/3/2026 12:35:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/4/2026 6:14:00 AM. 50 Economy ticket for $520 per person are available. Travel duration is 17h 39m
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United Airlines2h 56m06:49 AMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/3/2026 6:49:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/3/2026 9:45:00 AM. 50 Economy ticket for $552 per person are available. Travel duration is 2h 56m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 5/3/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/4/2026 5:52:00 AM. 50 Economy ticket for $569 per person are available. Travel duration is 12h 7m
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Spirit Airlines17h 34m02:12 PMSan Antonio AirportSan Antonio Airport7:46 AMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/3/2026 2:12:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/4/2026 7:46:00 AM. 50 Economy ticket for $652 per person are available. Travel duration is 17h 34m
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Volaris14h 9m08:41 PMSan Antonio AirportSan Antonio Airport10:50 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/3/2026 8:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/4/2026 10:50:00 AM. 50 Economy ticket for $657 per person are available. Travel duration is 14h 9m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 5/4/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/6/2026 5:20:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 31h 25m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/4/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/5/2026 11:35:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 35h 0m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/4/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/5/2026 5:20:00 AM. 50 Economy ticket for $184 per person are available. Travel duration is 27h 50m
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Spirit Airlines29h 49m05:26 PMSan Antonio AirportSan Antonio Airport11:15 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/4/2026 5:26:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/5/2026 11:15:00 PM. 50 Economy ticket for $414 per person are available. Travel duration is 29h 49m
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Viva Aerobus22h 41m05:45 PMSan Antonio AirportSan Antonio Airport4:26 PMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 5/4/2026 5:45:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/5/2026 4:26:00 PM. 50 Economy ticket for $429 per person are available. Travel duration is 22h 41m
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Volaris13h 9m09:41 PMSan Antonio AirportSan Antonio Airport10:50 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/4/2026 9:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/5/2026 10:50:00 AM. 50 Economy ticket for $468 per person are available. Travel duration is 13h 9m
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Volaris18h 45m09:41 PMSan Antonio AirportSan Antonio Airport4:26 PMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/4/2026 9:41:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/5/2026 4:26:00 PM. 50 Economy ticket for $469 per person are available. Travel duration is 18h 45m
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Viva Aerobus20h 15m05:45 PMSan Antonio AirportSan Antonio Airport2:00 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 5/4/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/5/2026 2:00:00 PM. 50 Economy ticket for $474 per person are available. Travel duration is 20h 15m
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United Airlines2h 56m06:49 AMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/4/2026 6:49:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/4/2026 9:45:00 AM. 50 Economy ticket for $477 per person are available. Travel duration is 2h 56m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 5/5/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/7/2026 5:20:00 AM. 50 Economy ticket for $159 per person are available. Travel duration is 31h 25m
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Greyhound Lines Mexico36h 45m05:50 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/5/2026 5:50:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/6/2026 6:35:00 PM. 50 Economy ticket for $180 per person are available. Travel duration is 36h 45m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/5/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/6/2026 5:20:00 AM. 50 Economy ticket for $183 per person are available. Travel duration is 27h 50m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/5/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/6/2026 11:35:00 PM. 50 Economy ticket for $191 per person are available. Travel duration is 35h 0m
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Frontier Airlines24h 38m07:54 PMSan Antonio AirportSan Antonio Airport8:32 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/5/2026 7:54:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/6/2026 8:32:00 PM. 50 Economy ticket for $206 per person are available. Travel duration is 24h 38m
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Volaris14h 9m08:41 PMSan Antonio AirportSan Antonio Airport10:50 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/5/2026 8:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/6/2026 10:50:00 AM. 50 Economy ticket for $415 per person are available. Travel duration is 14h 9m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 5/5/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/6/2026 5:52:00 AM. 50 Economy ticket for $415 per person are available. Travel duration is 12h 7m
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Viva Aerobus22h 41m05:45 PMSan Antonio AirportSan Antonio Airport4:26 PMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 5/5/2026 5:45:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/6/2026 4:26:00 PM. 50 Economy ticket for $419 per person are available. Travel duration is 22h 41m
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Volaris19h 45m08:41 PMSan Antonio AirportSan Antonio Airport4:26 PMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/5/2026 8:41:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/6/2026 4:26:00 PM. 50 Economy ticket for $430 per person are available. Travel duration is 19h 45m
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United Airlines2h 56m06:49 AMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/5/2026 6:49:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/5/2026 9:45:00 AM. 50 Economy ticket for $477 per person are available. Travel duration is 2h 56m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/6/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/7/2026 5:20:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 27h 50m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/6/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/7/2026 11:35:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 35h 0m
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Valley Transit32h 20m09:00 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/6/2026 9:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/8/2026 5:20:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 32h 20m
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FlixBus51h 20m07:45 AMSan Antonio, TXPearl District11:05 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 5/6/2026 7:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/8/2026 11:05:00 AM. 50 Economy ticket for $174 per person are available. Travel duration is 51h 20m
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Tornado Bus Company23h 48m011:05 AMSan Antonio, TXTornado Bus Company10:52 AMChicagoCalifornia & 35th Street Bus Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 5/6/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 5/7/2026 10:52:30 AM. 50 Basic ticket for $255 per person are available. Travel duration is 23h 48m
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Frontier Airlines24h 38m07:54 PMSan Antonio AirportSan Antonio Airport8:32 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/6/2026 7:54:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/7/2026 8:32:00 PM. 50 Economy ticket for $207 per person are available. Travel duration is 24h 38m
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Volaris13h 9m09:41 PMSan Antonio AirportSan Antonio Airport10:50 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/6/2026 9:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/7/2026 10:50:00 AM. 50 Economy ticket for $361 per person are available. Travel duration is 13h 9m
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Volaris18h 31m09:41 PMSan Antonio AirportSan Antonio Airport4:12 PMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/6/2026 9:41:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/7/2026 4:12:00 PM. 50 Economy ticket for $379 per person are available. Travel duration is 18h 31m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 5/6/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/7/2026 5:52:00 AM. 50 Economy ticket for $400 per person are available. Travel duration is 12h 7m
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Viva Aerobus22h 27m05:45 PMSan Antonio AirportSan Antonio Airport4:12 PMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 5/6/2026 5:45:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/7/2026 4:12:00 PM. 50 Economy ticket for $405 per person are available. Travel duration is 22h 27m
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United Airlines2h 56m06:49 AMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/6/2026 6:49:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/6/2026 9:45:00 AM. 50 Economy ticket for $477 per person are available. Travel duration is 2h 56m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/8/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/9/2026 5:20:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 27h 50m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/8/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/9/2026 11:35:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 35h 0m
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Valley Transit32h 5m09:15 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/8/2026 9:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/10/2026 5:20:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 32h 5m
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FlixBus35h 5m07:30 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 5/8/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/9/2026 6:35:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 35h 5m
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Tornado Bus Company24h 16m011:05 AMSan Antonio, TXTornado Bus Company11:21 AMChicagoCalifornia & 35th Street Bus Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 5/8/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 5/9/2026 11:21:00 AM. 50 Basic ticket for $255 per person are available. Travel duration is 24h 16m
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Frontier Airlines24h 38m07:54 PMSan Antonio AirportSan Antonio Airport8:32 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/8/2026 7:54:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/9/2026 8:32:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 24h 38m
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Spirit Airlines14h 56m05:26 PMSan Antonio AirportSan Antonio Airport8:22 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/8/2026 5:26:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/9/2026 8:22:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 14h 56m
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Spirit Airlines17h 38m05:26 PMSan Antonio AirportSan Antonio Airport11:04 AMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/8/2026 5:26:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/9/2026 11:04:00 AM. 50 Economy ticket for $177 per person are available. Travel duration is 17h 38m
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Frontier Airlines15h 10m07:54 PMSan Antonio AirportSan Antonio Airport11:04 AMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/8/2026 7:54:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/9/2026 11:04:00 AM. 50 Economy ticket for $186 per person are available. Travel duration is 15h 10m
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United Airlines2h 56m06:49 AMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/8/2026 6:49:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/8/2026 9:45:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 2h 56m
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Volaris13h 9m09:41 PMSan Antonio AirportSan Antonio Airport10:50 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/8/2026 9:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/9/2026 10:50:00 AM. 50 Economy ticket for $267 per person are available. Travel duration is 13h 9m
Cheapest Buses Friday
Cheapest Flights Friday
What are the fastest trips from San Antonio, TX to Chicago?
You can get to Chicago from San Antonio, TX in just 2h 56m with a Flight from United Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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United Airlines2h 56m06:49 AMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/2/2026 6:49:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/2/2026 9:45:00 AM. 50 Economy ticket for $477 per person are available. Travel duration is 2h 56m
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Spirit Airlines8h 55m02:12 PMSan Antonio AirportSan Antonio Airport11:07 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/2/2026 2:12:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/2/2026 11:07:00 PM. 50 Economy ticket for $308 per person are available. Travel duration is 8h 55m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 5/2/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/3/2026 5:52:00 AM. 50 Economy ticket for $569 per person are available. Travel duration is 12h 7m
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Volaris14h 9m08:41 PMSan Antonio AirportSan Antonio Airport10:50 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/2/2026 8:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/3/2026 10:50:00 AM. 50 Economy ticket for $500 per person are available. Travel duration is 14h 9m
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Spirit Airlines17h 29m02:12 PMSan Antonio AirportSan Antonio Airport7:41 AMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/2/2026 2:12:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/3/2026 7:41:00 AM. 50 Economy ticket for $602 per person are available. Travel duration is 17h 29m
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Frontier Airlines17h 41m04:04 PMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/2/2026 4:04:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/3/2026 9:45:00 AM. 50 Economy ticket for $271 per person are available. Travel duration is 17h 41m
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Tornado Bus Company24h 2m011:05 AMSan Antonio, TXTornado Bus Company11:07 AMChicagoCalifornia & 35th Street Bus Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 5/2/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 5/3/2026 11:07:30 AM. 50 Basic ticket for $255 per person are available. Travel duration is 24h 2m
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Tornado Bus Company24h 16m011:05 AMSan Antonio, TXTornado Bus Company11:21 AMChicagoCalifornia & 35th Street Bus Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 5/2/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 5/3/2026 11:21:00 AM. 50 Basic ticket for $255 per person are available. Travel duration is 24h 16m
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 5/2/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/4/2026 5:20:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 31h 25m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/2/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/3/2026 11:35:00 PM. 50 Economy ticket for $301 per person are available. Travel duration is 35h 0m
Fastest Flights Saturday
Fastest Buses Saturday
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United Airlines2h 56m06:49 AMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/3/2026 6:49:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/3/2026 9:45:00 AM. 50 Economy ticket for $552 per person are available. Travel duration is 2h 56m
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Spirit Airlines8h 55m02:12 PMSan Antonio AirportSan Antonio Airport11:07 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/3/2026 2:12:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/3/2026 11:07:00 PM. 50 Economy ticket for $353 per person are available. Travel duration is 8h 55m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 5/3/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/4/2026 5:52:00 AM. 50 Economy ticket for $569 per person are available. Travel duration is 12h 7m
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Volaris14h 9m08:41 PMSan Antonio AirportSan Antonio Airport10:50 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/3/2026 8:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/4/2026 10:50:00 AM. 50 Economy ticket for $657 per person are available. Travel duration is 14h 9m
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Spirit Airlines17h 34m02:12 PMSan Antonio AirportSan Antonio Airport7:46 AMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/3/2026 2:12:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/4/2026 7:46:00 AM. 50 Economy ticket for $652 per person are available. Travel duration is 17h 34m
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Frontier Airlines17h 39m012:35 PMSan Antonio AirportSan Antonio Airport6:14 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/3/2026 12:35:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/4/2026 6:14:00 AM. 50 Economy ticket for $520 per person are available. Travel duration is 17h 39m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/3/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/4/2026 5:20:00 AM. 50 Economy ticket for $205 per person are available. Travel duration is 27h 50m
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 5/3/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/5/2026 5:20:00 AM. 50 Economy ticket for $196 per person are available. Travel duration is 31h 25m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/3/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/4/2026 11:35:00 PM. 50 Economy ticket for $228 per person are available. Travel duration is 35h 0m
Fastest Flights Sunday
Fastest Buses Sunday
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United Airlines2h 56m06:49 AMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/4/2026 6:49:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/4/2026 9:45:00 AM. 50 Economy ticket for $477 per person are available. Travel duration is 2h 56m
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Alaska Airlines12h 39m06:01 PMSan Antonio AirportSan Antonio Airport6:40 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/4/2026 6:01:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/5/2026 6:40:00 AM. 50 Economy ticket for $771 per person are available. Travel duration is 12h 39m
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Volaris13h 9m09:41 PMSan Antonio AirportSan Antonio Airport10:50 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/4/2026 9:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/5/2026 10:50:00 AM. 50 Economy ticket for $468 per person are available. Travel duration is 13h 9m
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Frontier Airlines16h 38m06:31 PMSan Antonio AirportSan Antonio Airport11:09 AMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/4/2026 6:31:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/5/2026 11:09:00 AM. 50 Economy ticket for $1,137 per person are available. Travel duration is 16h 38m
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Delta Air Lines17h 15m04:30 PMSan Antonio AirportSan Antonio Airport9:45 AMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Delta Air Lines goes from San Antonio Airport, San Antonio Airport (USA) at 5/4/2026 4:30:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/5/2026 9:45:00 AM. 50 Economy ticket for $1,016 per person are available. Travel duration is 17h 15m
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Volaris18h 45m09:41 PMSan Antonio AirportSan Antonio Airport4:26 PMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/4/2026 9:41:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/5/2026 4:26:00 PM. 50 Economy ticket for $469 per person are available. Travel duration is 18h 45m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/4/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/5/2026 5:20:00 AM. 50 Economy ticket for $184 per person are available. Travel duration is 27h 50m
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 5/4/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/6/2026 5:20:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 31h 25m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/4/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/5/2026 11:35:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 35h 0m
Fastest Flights Monday
Fastest Buses Monday
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United Airlines2h 56m06:49 AMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/5/2026 6:49:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/5/2026 9:45:00 AM. 50 Economy ticket for $477 per person are available. Travel duration is 2h 56m
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Skyscanner3h 2m05:34 PMSan Antonio AirportSan Antonio Airport8:36 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from San Antonio Airport, San Antonio Airport (USA) at 5/5/2026 5:34:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/5/2026 8:36:00 PM. 50 Economy ticket for $478 per person are available. Travel duration is 3h 2m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 5/5/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/6/2026 5:52:00 AM. 50 Economy ticket for $415 per person are available. Travel duration is 12h 7m
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Volaris14h 9m08:41 PMSan Antonio AirportSan Antonio Airport10:50 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/5/2026 8:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/6/2026 10:50:00 AM. 50 Economy ticket for $415 per person are available. Travel duration is 14h 9m
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Frontier Airlines17h 13m08:59 PMSan Antonio AirportSan Antonio Airport2:12 PMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/5/2026 8:59:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/6/2026 2:12:00 PM. 50 Economy ticket for $670 per person are available. Travel duration is 17h 13m
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Volaris19h 45m08:41 PMSan Antonio AirportSan Antonio Airport4:26 PMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/5/2026 8:41:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/6/2026 4:26:00 PM. 50 Economy ticket for $430 per person are available. Travel duration is 19h 45m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/5/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/6/2026 5:20:00 AM. 50 Economy ticket for $183 per person are available. Travel duration is 27h 50m
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 5/5/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/7/2026 5:20:00 AM. 50 Economy ticket for $159 per person are available. Travel duration is 31h 25m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/5/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/6/2026 11:35:00 PM. 50 Economy ticket for $191 per person are available. Travel duration is 35h 0m
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Greyhound Lines Mexico36h 45m05:50 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/5/2026 5:50:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/6/2026 6:35:00 PM. 50 Economy ticket for $180 per person are available. Travel duration is 36h 45m
Fastest Flights Tuesday
Fastest Buses Tuesday
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United Airlines2h 56m06:49 AMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/6/2026 6:49:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/6/2026 9:45:00 AM. 50 Economy ticket for $477 per person are available. Travel duration is 2h 56m
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Skyscanner3h 1m05:34 PMSan Antonio AirportSan Antonio Airport8:35 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from San Antonio Airport, San Antonio Airport (USA) at 5/6/2026 5:34:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/6/2026 8:35:00 PM. 50 Economy ticket for $478 per person are available. Travel duration is 3h 1m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 5/6/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/7/2026 5:52:00 AM. 50 Economy ticket for $400 per person are available. Travel duration is 12h 7m
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Volaris13h 9m09:41 PMSan Antonio AirportSan Antonio Airport10:50 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/6/2026 9:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/7/2026 10:50:00 AM. 50 Economy ticket for $361 per person are available. Travel duration is 13h 9m
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Frontier Airlines17h 13m08:59 PMSan Antonio AirportSan Antonio Airport2:12 PMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/6/2026 8:59:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/7/2026 2:12:00 PM. 50 Economy ticket for $697 per person are available. Travel duration is 17h 13m
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Volaris18h 31m09:41 PMSan Antonio AirportSan Antonio Airport4:12 PMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/6/2026 9:41:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/7/2026 4:12:00 PM. 50 Economy ticket for $379 per person are available. Travel duration is 18h 31m
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Tornado Bus Company23h 48m011:05 AMSan Antonio, TXTornado Bus Company10:52 AMChicagoCalifornia & 35th Street Bus Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 5/6/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 5/7/2026 10:52:30 AM. 50 Basic ticket for $255 per person are available. Travel duration is 23h 48m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/6/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/7/2026 5:20:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 27h 50m
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Valley Transit32h 20m09:00 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/6/2026 9:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/8/2026 5:20:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 32h 20m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/6/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/7/2026 11:35:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 35h 0m
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FlixBus51h 20m07:45 AMSan Antonio, TXPearl District11:05 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 5/6/2026 7:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/8/2026 11:05:00 AM. 50 Economy ticket for $174 per person are available. Travel duration is 51h 20m
Fastest Flights Wednesday
Fastest Buses Wednesday
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United Airlines2h 56m06:49 AMSan Antonio AirportSan Antonio Airport9:45 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/8/2026 6:49:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/8/2026 9:45:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 2h 56m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 5/8/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/9/2026 5:52:00 AM. 50 Economy ticket for $335 per person are available. Travel duration is 12h 7m
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Volaris13h 9m09:41 PMSan Antonio AirportSan Antonio Airport10:50 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 5/8/2026 9:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/9/2026 10:50:00 AM. 50 Economy ticket for $267 per person are available. Travel duration is 13h 9m
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Frontier Airlines14h 5m08:59 PMSan Antonio AirportSan Antonio Airport11:04 AMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/8/2026 8:59:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/9/2026 11:04:00 AM. 50 Economy ticket for $283 per person are available. Travel duration is 14h 5m
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Spirit Airlines14h 56m05:26 PMSan Antonio AirportSan Antonio Airport8:22 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/8/2026 5:26:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 5/9/2026 8:22:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 14h 56m
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Frontier Airlines15h 10m07:54 PMSan Antonio AirportSan Antonio Airport11:04 AMChicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 5/8/2026 7:54:00 PM to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 5/9/2026 11:04:00 AM. 50 Economy ticket for $186 per person are available. Travel duration is 15h 10m
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Tornado Bus Company24h 16m011:05 AMSan Antonio, TXTornado Bus Company11:21 AMChicagoCalifornia & 35th Street Bus Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 5/8/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 5/9/2026 11:21:00 AM. 50 Basic ticket for $255 per person are available. Travel duration is 24h 16m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/8/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/9/2026 5:20:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 27h 50m
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Valley Transit32h 5m09:15 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/8/2026 9:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/10/2026 5:20:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 32h 5m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/8/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 5/9/2026 11:35:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 35h 0m
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FlixBus35h 5m07:30 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 5/8/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 5/9/2026 6:35:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 35h 5m
Fastest Flights Friday
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from San Antonio, TX to Chicago
What are the most popular stations in San Antonio, TX and Chicago?
In San Antonio, TX, you will usually depart from Tornado Bus Company, Bus Station or W. Southcross & Buffalo Bus Stop, while in Chicago you will be arriving at California & 35th Street Bus Stop, Downtown Bus Station or 95th Red Line Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Chicago from San Antonio, TX? With 14 connections between 7 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between San Antonio, TX and Chicago, you can pay as low as $106 with a Bus from Greyhound Lines Mexico.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Chicago in just 2h 56m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting San Antonio, TX and Chicago are Viva Aerobus, Volaris and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in San Antonio, TX and Chicago is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Olmos Park, TX or to Cicero, IL, and look at flights from San Antonio Airport, and landing at Chicago Midway Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from San Antonio, TX to Chicago?
The most popular companies between San Antonio, TX and Chicago, are Viva Aerobus, Volaris and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, Greyhound US, Greyhound Lines Mexico and 2 more.
Airlines: Viva Aerobus, Volaris, Spirit Airlines and 5 more.
All you need to know when you travel from San Antonio, TX to Chicago
Check all information on comfort and services on all modes of transports from San Antonio, TX to Chicago. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from San Antonio, TX to Chicago
How can I reach Chicago from San Antonio, TX?
Every day, there are on average 14 connections between Flight and Bus, with which you can get to Chicago from San Antonio, TX.
How far is Chicago from San Antonio, TX?
The distance between San Antonio, TX and Chicago is 1,052.2 miles.
What is the most ecofriendly mode of transport between San Antonio, TX and Chicago?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 46 kgs of CO2, a train 59 kgs, a car 288 kgs, and a flight 417 kgs.
What is the cheapest mode of transport from San Antonio, TX to Chicago?
You can get to Chicago with just $106 by taking a Bus from Greyhound Lines Mexico.
What is the fastest way to get from San Antonio, TX to Chicago?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Chicago in just 2h 56m with a Flight from United Airlines.
More routes to San Antonio, TX and to Chicago
Looking for more options? Here you can see the most popular routes to San Antonio, TX and to Chicago. Simply click on a connection, and you’ll find all the details about the route!
- Trips to San Antonio, TX
- Aguascalientes to San Antonio, TX
- Albuquerque, NM to San Antonio, TX
- Atlanta, GA to San Antonio, TX
- Brownsville, TX to San Antonio, TX
- Durango, DG to San Antonio, TX
- El Paso, TX to San Antonio, TX
- Fort Worth to San Antonio, TX
- Guadalajara, JC to San Antonio, TX
- Houston to San Antonio, TX
- McAllen, TX to San Antonio, TX
- Mexico City to San Antonio, TX
- Monterrey, NL to San Antonio, TX
- Phoenix, AZ to San Antonio, TX
- Saltillo to San Antonio, TX
- San Diego to San Antonio, TX
- San Luis Potosí to San Antonio, TX
- Santiago de Queretaro to San Antonio, TX
- Torreón, CO to San Antonio, TX
- Zacatecas, ZS to San Antonio, TX
- Trips to Chicago
- Aguascalientes to Chicago
- Atlanta, GA to Chicago
- Bloomington, IN to Chicago
- Buffalo, NY to Chicago
- Cincinnati to Chicago
- Dallas to Chicago
- Durango, DG to Chicago
- El Paso, TX to Chicago
- Houston to Chicago
- Los Angeles to Chicago
- Louisville, KY to Chicago
- Memphis to Chicago
- Mexico City to Chicago
- Montreal to Chicago
- Nashville to Chicago
- New York to Chicago
- Nuevo Laredo to Chicago
- Pearson Toronto Airport to Chicago
- Pittsburgh to Chicago
- Santiago de Queretaro to Chicago
- Toronto, ON to Chicago
- Zacatecas, ZS to Chicago
