What is the best way to travel from San Antonio, TX to Chicago?
Looking for a trip? Compare all the available Flights and Buses for the journey to Chicago from San Antonio, TX. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 7 available companies to find your perfect trip!
What is the cheapest way to reach Chicago from San Antonio, TX?
You can get to Chicago with just $105 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus35h 5m07:30 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/20/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/21/2026 6:35:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 35h 5m
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Greyhound US27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/20/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/21/2026 5:20:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 27h 50m
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Valley Transit32h 5m09:15 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 6/20/2026 9:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/22/2026 5:20:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 32h 5m
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Greyhound Lines Mexico30h 30m01:30 AMSan Antonio, TXBus Station8:00 AMChicagoUnion Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/20/2026 1:30:00 AM to Union Station, Chicago (USA) arriving at 6/21/2026 8:00:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 30h 30m
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Tornado Bus Company24h 16m011:05 AMSan Antonio, TXTornado Bus Company11:21 AMChicagoCalifornia & 35th Street Bus Stop0EconomyA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 6/20/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 6/21/2026 11:21:00 AM. 50 Economy ticket for $255 per person are available. Travel duration is 24h 16m
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United Airlines3h 1m01:20 PMSan Antonio AirportSan Antonio Airport4:21 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/20/2026 1:20:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/20/2026 4:21:00 PM. 50 Economy ticket for $184 per person are available. Travel duration is 3h 1m
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Frontier Airlines24h 52m07:51 PMSan Antonio AirportSan Antonio Airport8:43 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/20/2026 7:51:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/21/2026 8:43:00 PM. 50 Economy ticket for $361 per person are available. Travel duration is 24h 52m
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Volaris22h 14m012:41 PMSan Antonio AirportSan Antonio Airport10:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 6/20/2026 12:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/21/2026 10:55:00 AM. 50 Economy ticket for $445 per person are available. Travel duration is 22h 14m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 6/20/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/21/2026 5:52:00 AM. 50 Economy ticket for $490 per person are available. Travel duration is 12h 7m
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Alaska Airlines13h 36m04:44 PMSan Antonio AirportSan Antonio Airport6:20 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/20/2026 4:44:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/21/2026 6:20:00 AM. 50 Economy ticket for $528 per person are available. Travel duration is 13h 36m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/21/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/22/2026 5:20:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 27h 50m
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/21/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/23/2026 5:20:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 31h 25m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/21/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/22/2026 11:35:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 35h 0m
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FlixBus35h 5m07:30 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/21/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/22/2026 6:35:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 35h 5m
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Frontier Airlines8h 11m08:56 PMSan Antonio AirportSan Antonio Airport5:07 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/21/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/22/2026 5:07:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 8h 11m
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United Airlines2h 58m06:40 AMSan Antonio AirportSan Antonio Airport9:38 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/21/2026 6:40:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/21/2026 9:38:00 AM. 50 Economy ticket for $224 per person are available. Travel duration is 2h 58m
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Volaris13h 59m08:56 PMSan Antonio AirportSan Antonio Airport10:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 6/21/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/22/2026 10:55:00 AM. 50 Economy ticket for $381 per person are available. Travel duration is 13h 59m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 6/21/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/22/2026 5:52:00 AM. 50 Economy ticket for $407 per person are available. Travel duration is 12h 7m
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Aeroméxico21h 8m01:47 PMSan Antonio AirportSan Antonio Airport10:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Aeroméxico goes from San Antonio Airport, San Antonio Airport (USA) at 6/21/2026 1:47:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/22/2026 10:55:00 AM. 50 Economy ticket for $472 per person are available. Travel duration is 21h 8m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/22/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/24/2026 5:20:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 31h 25m
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Greyhound US31h 35m012:35 PMSan Antonio, TXBus Station8:10 PMChicagoDowntown Bus Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/22/2026 12:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/23/2026 8:10:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 31h 35m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/22/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/23/2026 11:35:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 35h 0m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/22/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/23/2026 5:20:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 27h 50m
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Frontier Airlines8h 11m08:56 PMSan Antonio AirportSan Antonio Airport5:07 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/22/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/23/2026 5:07:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 8h 11m
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United Airlines2h 58m06:40 AMSan Antonio AirportSan Antonio Airport9:38 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/22/2026 6:40:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/22/2026 9:38:00 AM. 50 Economy ticket for $184 per person are available. Travel duration is 2h 58m
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Volaris13h 59m08:56 PMSan Antonio AirportSan Antonio Airport10:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 6/22/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/23/2026 10:55:00 AM. 50 Economy ticket for $347 per person are available. Travel duration is 13h 59m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 6/22/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/23/2026 5:52:00 AM. 50 Economy ticket for $411 per person are available. Travel duration is 12h 7m
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Alaska Airlines16h 57m07:02 AMSan Antonio AirportSan Antonio Airport11:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/22/2026 7:02:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/22/2026 11:59:00 PM. 50 Economy ticket for $511 per person are available. Travel duration is 16h 57m
Cheapest Buses Monday
Cheapest Flights Monday
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Frontier Airlines8h 11m08:56 PMSan Antonio AirportSan Antonio Airport5:07 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/23/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/24/2026 5:07:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 8h 11m
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United Airlines2h 58m06:40 AMSan Antonio AirportSan Antonio Airport9:38 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/23/2026 6:40:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/23/2026 9:38:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 2h 58m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 6/23/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/24/2026 5:52:00 AM. 50 Economy ticket for $397 per person are available. Travel duration is 12h 7m
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Volaris26h 23m09:32 PMSan Antonio AirportSan Antonio Airport11:55 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 6/23/2026 9:32:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/24/2026 11:55:00 PM. 50 Economy ticket for $433 per person are available. Travel duration is 26h 23m
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Alaska Airlines16h 57m07:02 AMSan Antonio AirportSan Antonio Airport11:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/23/2026 7:02:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/23/2026 11:59:00 PM. 50 Economy ticket for $456 per person are available. Travel duration is 16h 57m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/23/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/24/2026 5:20:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 27h 50m
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/23/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/25/2026 5:20:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 31h 25m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/23/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/24/2026 11:35:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 35h 0m
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Greyhound Lines Mexico36h 45m05:50 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/23/2026 5:50:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/24/2026 6:35:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 36h 45m
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FlixBus34h 5m09:55 PMSan Antonio, TXBus Station8:00 AMChicagoUnion Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/23/2026 9:55:00 PM to Union Station, Chicago (USA) arriving at 6/25/2026 8:00:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 34h 5m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
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Greyhound US27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/24/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/25/2026 5:20:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 27h 50m
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Valley Transit32h 20m09:00 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 6/24/2026 9:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2026 5:20:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 32h 20m
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Greyhound Lines Mexico30h 30m01:30 AMSan Antonio, TXBus Station8:00 AMChicagoUnion Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/24/2026 1:30:00 AM to Union Station, Chicago (USA) arriving at 6/25/2026 8:00:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 30h 30m
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FlixBus31h 20m09:00 PMSan Antonio, TXBus Station4:20 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/24/2026 9:00:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/26/2026 4:20:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 31h 20m
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Tornado Bus Company24h 16m011:05 AMSan Antonio, TXTornado Bus Company11:21 AMChicagoCalifornia & 35th Street Bus Stop0EconomyA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 6/24/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 6/25/2026 11:21:00 AM. 50 Economy ticket for $255 per person are available. Travel duration is 24h 16m
Cheapest Buses Wednesday
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FlixBus35h 5m07:30 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/25/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2026 6:35:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 35h 5m
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Greyhound US27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/25/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2026 5:20:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 27h 50m
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Valley Transit32h 20m09:00 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 6/25/2026 9:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/27/2026 5:20:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 32h 20m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/25/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2026 5:20:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 27h 50m
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Tornado Bus Company24h 16m011:05 AMSan Antonio, TXTornado Bus Company11:21 AMChicagoCalifornia & 35th Street Bus Stop0EconomyA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 6/25/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 6/26/2026 11:21:00 AM. 50 Economy ticket for $255 per person are available. Travel duration is 24h 16m
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Frontier Airlines8h 11m08:56 PMSan Antonio AirportSan Antonio Airport5:07 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/25/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/26/2026 5:07:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 8h 11m
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United Airlines2h 58m06:40 AMSan Antonio AirportSan Antonio Airport9:38 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/25/2026 6:40:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/25/2026 9:38:00 AM. 50 Economy ticket for $184 per person are available. Travel duration is 2h 58m
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Sun Country Airlines22h 59m06:25 PMSan Antonio AirportSan Antonio Airport5:24 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Sun Country Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/25/2026 6:25:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/26/2026 5:24:00 PM. 50 Economy ticket for $266 per person are available. Travel duration is 22h 59m
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Volaris13h 59m08:56 PMSan Antonio AirportSan Antonio Airport10:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 6/25/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/26/2026 10:55:00 AM. 50 Economy ticket for $291 per person are available. Travel duration is 13h 59m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 6/25/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/26/2026 5:52:00 AM. 50 Economy ticket for $417 per person are available. Travel duration is 12h 7m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/26/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/27/2026 5:20:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 27h 50m
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/26/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/28/2026 5:20:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 31h 25m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/26/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/27/2026 11:35:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 35h 0m
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FlixBus35h 5m07:30 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/26/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/27/2026 6:35:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 35h 5m
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Greyhound Lines Mexico33h 25m05:50 AMSan Antonio, TXBus Station3:15 PMChicagoDowntown Bus Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/26/2026 5:50:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/27/2026 3:15:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 33h 25m
Cheapest Buses Friday
What are the fastest trips from San Antonio, TX to Chicago?
You can get to Chicago from San Antonio, TX in just 2h 58m with a Flight from United Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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United Airlines3h 1m01:20 PMSan Antonio AirportSan Antonio Airport4:21 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/20/2026 1:20:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/20/2026 4:21:00 PM. 50 Economy ticket for $184 per person are available. Travel duration is 3h 1m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 6/20/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/21/2026 5:52:00 AM. 50 Economy ticket for $490 per person are available. Travel duration is 12h 7m
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Alaska Airlines13h 36m04:44 PMSan Antonio AirportSan Antonio Airport6:20 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/20/2026 4:44:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/21/2026 6:20:00 AM. 50 Economy ticket for $528 per person are available. Travel duration is 13h 36m
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Volaris22h 14m012:41 PMSan Antonio AirportSan Antonio Airport10:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 6/20/2026 12:41:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/21/2026 10:55:00 AM. 50 Economy ticket for $445 per person are available. Travel duration is 22h 14m
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Frontier Airlines24h 52m07:51 PMSan Antonio AirportSan Antonio Airport8:43 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/20/2026 7:51:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/21/2026 8:43:00 PM. 50 Economy ticket for $361 per person are available. Travel duration is 24h 52m
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Tornado Bus Company24h 16m011:05 AMSan Antonio, TXTornado Bus Company11:21 AMChicagoCalifornia & 35th Street Bus Stop0EconomyA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 6/20/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 6/21/2026 11:21:00 AM. 50 Economy ticket for $255 per person are available. Travel duration is 24h 16m
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Greyhound US27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/20/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/21/2026 5:20:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 27h 50m
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Greyhound Lines Mexico30h 30m01:30 AMSan Antonio, TXBus Station8:00 AMChicagoUnion Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/20/2026 1:30:00 AM to Union Station, Chicago (USA) arriving at 6/21/2026 8:00:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 30h 30m
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Valley Transit32h 5m09:15 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 6/20/2026 9:15:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/22/2026 5:20:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 32h 5m
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FlixBus35h 5m07:30 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/20/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/21/2026 6:35:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 35h 5m
Fastest Flights Saturday
Fastest Buses Saturday
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United Airlines2h 58m06:40 AMSan Antonio AirportSan Antonio Airport9:38 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/21/2026 6:40:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/21/2026 9:38:00 AM. 50 Economy ticket for $224 per person are available. Travel duration is 2h 58m
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Frontier Airlines8h 11m08:56 PMSan Antonio AirportSan Antonio Airport5:07 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/21/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/22/2026 5:07:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 8h 11m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 6/21/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/22/2026 5:52:00 AM. 50 Economy ticket for $407 per person are available. Travel duration is 12h 7m
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Volaris13h 59m08:56 PMSan Antonio AirportSan Antonio Airport10:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 6/21/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/22/2026 10:55:00 AM. 50 Economy ticket for $381 per person are available. Travel duration is 13h 59m
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Aeroméxico21h 8m01:47 PMSan Antonio AirportSan Antonio Airport10:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Aeroméxico goes from San Antonio Airport, San Antonio Airport (USA) at 6/21/2026 1:47:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/22/2026 10:55:00 AM. 50 Economy ticket for $472 per person are available. Travel duration is 21h 8m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/21/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/22/2026 5:20:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 27h 50m
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/21/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/23/2026 5:20:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 31h 25m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/21/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/22/2026 11:35:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 35h 0m
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FlixBus35h 5m07:30 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/21/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/22/2026 6:35:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 35h 5m
Fastest Flights Sunday
Fastest Buses Sunday
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United Airlines2h 58m06:40 AMSan Antonio AirportSan Antonio Airport9:38 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/22/2026 6:40:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/22/2026 9:38:00 AM. 50 Economy ticket for $184 per person are available. Travel duration is 2h 58m
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Frontier Airlines8h 11m08:56 PMSan Antonio AirportSan Antonio Airport5:07 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/22/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/23/2026 5:07:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 8h 11m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 6/22/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/23/2026 5:52:00 AM. 50 Economy ticket for $411 per person are available. Travel duration is 12h 7m
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Volaris13h 59m08:56 PMSan Antonio AirportSan Antonio Airport10:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 6/22/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/23/2026 10:55:00 AM. 50 Economy ticket for $347 per person are available. Travel duration is 13h 59m
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Alaska Airlines16h 57m07:02 AMSan Antonio AirportSan Antonio Airport11:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/22/2026 7:02:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/22/2026 11:59:00 PM. 50 Economy ticket for $511 per person are available. Travel duration is 16h 57m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/22/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/23/2026 5:20:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 27h 50m
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/22/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/24/2026 5:20:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 31h 25m
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Greyhound US31h 35m012:35 PMSan Antonio, TXBus Station8:10 PMChicagoDowntown Bus Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/22/2026 12:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/23/2026 8:10:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 31h 35m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/22/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/23/2026 11:35:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 35h 0m
Fastest Flights Monday
Fastest Buses Monday
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United Airlines2h 58m06:40 AMSan Antonio AirportSan Antonio Airport9:38 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/23/2026 6:40:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/23/2026 9:38:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 2h 58m
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Frontier Airlines8h 11m08:56 PMSan Antonio AirportSan Antonio Airport5:07 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/23/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/24/2026 5:07:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 8h 11m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 6/23/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/24/2026 5:52:00 AM. 50 Economy ticket for $397 per person are available. Travel duration is 12h 7m
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Alaska Airlines16h 57m07:02 AMSan Antonio AirportSan Antonio Airport11:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/23/2026 7:02:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/23/2026 11:59:00 PM. 50 Economy ticket for $456 per person are available. Travel duration is 16h 57m
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Volaris26h 23m09:32 PMSan Antonio AirportSan Antonio Airport11:55 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 6/23/2026 9:32:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/24/2026 11:55:00 PM. 50 Economy ticket for $433 per person are available. Travel duration is 26h 23m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/23/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/24/2026 5:20:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 27h 50m
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/23/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/25/2026 5:20:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 31h 25m
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FlixBus34h 5m09:55 PMSan Antonio, TXBus Station8:00 AMChicagoUnion Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/23/2026 9:55:00 PM to Union Station, Chicago (USA) arriving at 6/25/2026 8:00:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 34h 5m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/23/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/24/2026 11:35:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 35h 0m
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Greyhound Lines Mexico36h 45m05:50 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/23/2026 5:50:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/24/2026 6:35:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 36h 45m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Tornado Bus Company24h 16m011:05 AMSan Antonio, TXTornado Bus Company11:21 AMChicagoCalifornia & 35th Street Bus Stop0EconomyA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 6/24/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 6/25/2026 11:21:00 AM. 50 Economy ticket for $255 per person are available. Travel duration is 24h 16m
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Greyhound US27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/24/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/25/2026 5:20:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 27h 50m
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Greyhound Lines Mexico30h 30m01:30 AMSan Antonio, TXBus Station8:00 AMChicagoUnion Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/24/2026 1:30:00 AM to Union Station, Chicago (USA) arriving at 6/25/2026 8:00:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 30h 30m
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FlixBus31h 20m09:00 PMSan Antonio, TXBus Station4:20 AMChicagoDowntown Bus Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/24/2026 9:00:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/26/2026 4:20:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 31h 20m
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Valley Transit32h 20m09:00 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 6/24/2026 9:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2026 5:20:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 32h 20m
Fastest Buses Wednesday
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United Airlines2h 58m06:40 AMSan Antonio AirportSan Antonio Airport9:38 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/25/2026 6:40:00 AM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/25/2026 9:38:00 AM. 50 Economy ticket for $184 per person are available. Travel duration is 2h 58m
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Frontier Airlines8h 11m08:56 PMSan Antonio AirportSan Antonio Airport5:07 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/25/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/26/2026 5:07:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 8h 11m
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Viva Aerobus12h 7m05:45 PMSan Antonio AirportSan Antonio Airport5:52 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 6/25/2026 5:45:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/26/2026 5:52:00 AM. 50 Economy ticket for $417 per person are available. Travel duration is 12h 7m
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Volaris13h 59m08:56 PMSan Antonio AirportSan Antonio Airport10:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 6/25/2026 8:56:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/26/2026 10:55:00 AM. 50 Economy ticket for $291 per person are available. Travel duration is 13h 59m
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Sun Country Airlines22h 59m06:25 PMSan Antonio AirportSan Antonio Airport5:24 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Sun Country Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 6/25/2026 6:25:00 PM to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 6/26/2026 5:24:00 PM. 50 Economy ticket for $266 per person are available. Travel duration is 22h 59m
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Tornado Bus Company24h 16m011:05 AMSan Antonio, TXTornado Bus Company11:21 AMChicagoCalifornia & 35th Street Bus Stop0EconomyA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 6/25/2026 11:05:00 AM to California & 35th Street Bus Stop, Chicago (USA) arriving at 6/26/2026 11:21:00 AM. 50 Economy ticket for $255 per person are available. Travel duration is 24h 16m
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Greyhound US27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/25/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2026 5:20:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 27h 50m
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/25/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2026 5:20:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 27h 50m
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Valley Transit32h 20m09:00 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 6/25/2026 9:00:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/27/2026 5:20:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 32h 20m
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FlixBus35h 5m07:30 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/25/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2026 6:35:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 35h 5m
Fastest Flights Thursday
Fastest Buses Thursday
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Greyhound Lines Mexico27h 50m01:30 AMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/26/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/27/2026 5:20:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 27h 50m
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FlixBus31h 25m09:55 PMSan Antonio, TXBus Station5:20 AMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/26/2026 9:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/28/2026 5:20:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 31h 25m
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Greyhound Lines Mexico33h 25m05:50 AMSan Antonio, TXBus Station3:15 PMChicagoDowntown Bus Station0EconomyA Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 6/26/2026 5:50:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/27/2026 3:15:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 33h 25m
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Greyhound US35h 0m012:35 PMSan Antonio, TXBus Station11:35 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 6/26/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/27/2026 11:35:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 35h 0m
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FlixBus35h 5m07:30 AMSan Antonio, TXBus Station6:35 PMChicago95th Red Line Station0EconomyA Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 6/26/2026 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/27/2026 6:35:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 35h 5m
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from San Antonio, TX to Chicago
What are the most popular stations in San Antonio, TX and Chicago?
In San Antonio, TX, you will usually depart from Tornado Bus Company, Bus Station or W. Southcross & Buffalo Bus Stop, while in Chicago you will be arriving at California & 35th Street Bus Stop, Downtown Bus Station or 95th Red Line Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Chicago from San Antonio, TX? With 8 connections between 7 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between San Antonio, TX and Chicago, you can pay as low as $105 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Chicago in just 2h 58m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting San Antonio, TX and Chicago are FlixBus, Greyhound Lines Mexico and Greyhound US, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in San Antonio, TX and Chicago is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Olmos Park, TX or to Cicero, IL, and look at flights from San Antonio Airport, and landing at Chicago Midway Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from San Antonio, TX to Chicago?
The most popular companies between San Antonio, TX and Chicago, are FlixBus, Greyhound Lines Mexico and Greyhound US. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, Greyhound Lines Mexico, Greyhound US and 2 more.
Airlines: United Airlines, Frontier Airlines, Volaris and 4 more.
All you need to know when you travel from San Antonio, TX to Chicago
Check all information on comfort and services on all modes of transports from San Antonio, TX to Chicago. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from San Antonio, TX to Chicago
How can I reach Chicago from San Antonio, TX?
Every day, there are on average 8 connections between Flight and Bus, with which you can get to Chicago from San Antonio, TX.
How far is Chicago from San Antonio, TX?
The distance between San Antonio, TX and Chicago is 1,052.2 miles.
What is the most ecofriendly mode of transport between San Antonio, TX and Chicago?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 46 kgs of CO2, a train 59 kgs, a car 288 kgs, and a flight 417 kgs.
What is the cheapest mode of transport from San Antonio, TX to Chicago?
You can get to Chicago with just $105 by taking a Bus from FlixBus.
What is the fastest way to get from San Antonio, TX to Chicago?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Chicago in just 2h 58m with a Flight from United Airlines.
More routes to San Antonio, TX and to Chicago
Looking for more options? Here you can see the most popular routes to San Antonio, TX and to Chicago. Simply click on a connection, and you’ll find all the details about the route!
