Bus Madison, WI to Florence, SC: Compare prices and save money

Compare all timetables for the bus from Madison, WI to Florence, SC

Here is a selection of the cheapest bus trips from the schedule from Madison, WI to Florence, SC from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

Sunday

Monday

Tuesday

Wednesday

$121

Thursday

$121

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 40m	10:50 AM	Madison, WI	W Transfer Point	3:30 PM	Florence, SC	Bus Station	Economy	$121	A Bus from Greyhound US goes from W Transfer Point, Madison, WI (USA) at 12/10/2025 10:50:00 AM to Bus Station, Florence, SC (USA) arriving at 12/11/2025 3:30:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 27h 40m
FlixBus	29h 30m	7:00 AM	Madison, WI	W Transfer Point	1:30 PM	Florence, SC	Bus Station	Economy	$132	A Bus from FlixBus goes from W Transfer Point, Madison, WI (USA) at 12/10/2025 7:00:00 AM to Bus Station, Florence, SC (USA) arriving at 12/11/2025 1:30:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 29h 30m
FlixBus	33h 40m	1:25 PM	Madison, WI	University Wisconsin-Madison	12:05 AM	Florence, SC	TA Travel Center	Economy	$132	A Bus from FlixBus goes from University Wisconsin-Madison, Madison, WI (USA) at 12/10/2025 1:25:00 PM to TA Travel Center, Florence, SC (USA) arriving at 12/12/2025 12:05:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 33h 40m
FlixBus	33h 20m	1:45 PM	Madison, WI	W Transfer Point	12:05 AM	Florence, SC	TA Travel Center	Economy	$132	A Bus from FlixBus goes from W Transfer Point, Madison, WI (USA) at 12/10/2025 1:45:00 PM to TA Travel Center, Florence, SC (USA) arriving at 12/12/2025 12:05:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 33h 20m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 40m	10:50 AM	Madison, WI	W Transfer Point	3:30 PM	Florence, SC	Bus Station	Economy	$121	A Bus from Greyhound US goes from W Transfer Point, Madison, WI (USA) at 12/11/2025 10:50:00 AM to Bus Station, Florence, SC (USA) arriving at 12/12/2025 3:30:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 27h 40m
FlixBus	29h 45m	6:45 AM	Madison, WI	University Wisconsin-Madison	1:30 PM	Florence, SC	Bus Station	Economy	$133	A Bus from FlixBus goes from University Wisconsin-Madison, Madison, WI (USA) at 12/11/2025 6:45:00 AM to Bus Station, Florence, SC (USA) arriving at 12/12/2025 1:30:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 29h 45m
FlixBus	33h 40m	1:25 PM	Madison, WI	University Wisconsin-Madison	12:05 AM	Florence, SC	TA Travel Center	Economy	$133	A Bus from FlixBus goes from University Wisconsin-Madison, Madison, WI (USA) at 12/11/2025 1:25:00 PM to TA Travel Center, Florence, SC (USA) arriving at 12/13/2025 12:05:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 33h 40m
FlixBus	33h 20m	1:45 PM	Madison, WI	W Transfer Point	12:05 AM	Florence, SC	TA Travel Center	Economy	$133	A Bus from FlixBus goes from W Transfer Point, Madison, WI (USA) at 12/11/2025 1:45:00 PM to TA Travel Center, Florence, SC (USA) arriving at 12/13/2025 12:05:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 33h 20m

Best Price Offer: The price for the cheapest bus from Madison, WI to Florence, SC is $121 on 12/10/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Madison, WI and Florence, SC

See here how frequent the connections between Madison, WI and Florence, SC are, during different times and days of the week.

Wednesday is the busiest day, with more than 9 daily buses from Madison, WI to Florence, SC. Wednesday has instead the fewest connections, with only 9 daily coaches between Madison, WI and Florence, SC.

The busiest time of the day is the Afternoon, with 12 buses from Madison, WI to Florence, SC, while Morning sees the fewest connections between Madison, WI and Florence, SC, with 6 offers.

Facts about the bus from Madison, WI to Florence, SC

Compare all providers like FlixBus and Greyhound US that travel 9 times every day by bus from Madison, WI to Florence, SC in one click! Book your bus ticket from Madison, WI to Florence, SC starting from $121!

Cheapest Bus	$121
Fastest Bus	28h 40m
Earliest Bus	6:45 AM
Latest Bus	5:40 PM
Daily Bus Routes	9 Ø
Distance	803.5 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Madison, WI to Florence, SC

Every day, 9 buses from 2 bus companies leave Madison, WI for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

Saturday 12/06

Sunday 12/07

Monday 12/08

Tuesday 12/09

Wednesday 12/10

$121

Thursday 12/11

$121

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Madison, WI to Florence, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Madison, WI to Florence, SC, for the next 30 days.

With a price starting from $121, Wednesday is the cheapest day for a bus from Madison, WI to Florence, SC. Wednesday instead is the most expensive day with prices starting from $121.

Morning is the cheapest day time for bus tickets from Madison, WI to Florence, SC, with $121. Afternoon is the most expensive time of the day with prices starting from $132.

How to save money travelling from Madison, WI to Florence, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Madison, WI to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madison, WI to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Madison, WI to Florence, SC are also emptier.

Beloved bus companies from Madison, WI to Florence, SC

These are the most booked bus companies between Madison, WI to Florence, SC from our users.

FlixBus from Madison, WI to Florence, SC

Here you will find the key facts about the FlixBus bus route Madison, WI to Florence, SC:

Cheapest Price	$132
Fastest Bus	30h 30m
Earliest Bus	6:45 AM
Last Bus	5:40 PM
Daily Connections	8 Ø
Found on	12/2/2025

All bus stations and stops in Madison, WI and Florence, SC

In the map below, you can see where to find all bus stations in Madison, WI and Florence, SC.

Dutch Mill Park & Ride

E Broadway

Bus Stop

Memorial Union Building

Langdon Street 800

Chazen Museum

University Avenue 750-800

E Washington at E Johnson

TA Travel Center

W Lucas St 2301

Exxon Gas Station

W Lucas Street 1901

McDonalds

W. Lucas St. 1908

Shell Gas Station

W Lucas Street 1832

Bus Station

S Irby St 611

Service and Comfort on the bus from Madison, WI to Florence, SC

Want to know which seat classes are available on the buses from Madison, WI to Florence, SC? Or which bus companies serve the route Madison, WI to Florence, SC? Below you will find answers to your questions.

FAQs about the Madison, WI to Florence, SC bus

How much does a Madison, WI Florence, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $121 and takes 28h 40m to reach Florence, SC. Compare offers to save money!

How much could I save by comparing buses from Madison, WI to Florence, SC?

This route is offered by 2 companies with a range of ticket prices between $121 and $239. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.

On average, how many connections are available from Madison, WI to Florence, SC each day?

Every day, the Madison, WI to Florence, SC bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Madison, WI to Florence, SC take?

The fastest bus from Madison, WI to Florence, SC is offered by Greyhound US and takes 28h 40m. Bus tickets for this connection cost $121. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Madison, WI to Florence, SC?

The earliest bus arriving in Florence, SC from Madison, WI starts at 6:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Madison, WI to Florence, SC?

The latest bus trip departing from Madison, WI for Florence, SC starts at 5:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Madison, WI Florence, SC route?

When traveling by bus from Madison, WI to Florence, SC, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Madison, WI and Florence, SC?

You can check all the direct connections between Madison, WI and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Madison, WI to Florence, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Madison, WI Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Madison, WI Florence, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Madison, WI to Florence, SC on your planned travel date.

Available seat classes which are offered on the bus route Madison, WI to Florence, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Madison, WI and to Florence, SC

Here’s an overview of the most popular bus routes to Madison, WI and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!