Bus from Madison, WI to Florence, SC from $127

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Compare all timetables for the bus from Madison, WI to Florence, SC

Here is a selection of the cheapest bus trips from the schedule from Madison, WI to Florence, SC from various bus operators like FlixBus for the next days.

today
$132
tomorrow
$131
Wednesday
$216
Thursday
$129
Friday
$132
Saturday
$132
Sunday
$132

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 29h 30m 7:00 AM Madison, WI W Transfer Point 1:30 PM Florence, SC Bus Station  Economy $132
FlixBus 29h 45m 6:45 AM Madison, WI University Wisconsin-Madison 1:30 PM Florence, SC Bus Station  Economy $133
FlixBus 40h 50m 5:55 PM Madison, WI University Wisconsin-Madison 11:45 AM Florence, SC Bus Station  Economy $227
FlixBus 40h 35m 6:10 PM Madison, WI W Transfer Point 11:45 AM Florence, SC Bus Station  Economy $228

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 39h 0m 1:45 PM Madison, WI W Transfer Point 5:45 AM Florence, SC TA Travel Center  Economy $131
FlixBus 29h 30m 7:00 AM Madison, WI W Transfer Point 1:30 PM Florence, SC Bus Station  Economy $132
FlixBus 29h 45m 6:45 AM Madison, WI University Wisconsin-Madison 1:30 PM Florence, SC Bus Station  Economy $133
FlixBus 39h 20m 1:25 PM Madison, WI University Wisconsin-Madison 5:45 AM Florence, SC TA Travel Center  Economy $133
FlixBus 45h 20m 1:25 PM Madison, WI University Wisconsin-Madison 11:45 AM Florence, SC Bus Station  Economy $221

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 40h 50m 5:55 PM Madison, WI Chazen Museum 11:45 AM Florence, SC Bus Station  Economy $216
FlixBus 40h 35m 6:10 PM Madison, WI Dutch Mill Park & Ride 11:45 AM Florence, SC Bus Station  Economy $217
  • Did you know that if you travel from Madison, WI to Florence, SC via Indianapolis, you can save more than $90? You can find the corresponding connections below.
    • FlixBus
      29h 30m
      0
      7:00 AM
      Madison, WI
      W Transfer Point
      3:00 PM
      Indianapolis
      Washington / Delaware
      0
      FlixBus
      Economy
      $46
      • Waiting Time 1h 5m
    • Greyhound US
      21h 25m
      0
      4:05 PM
      Indianapolis
      Central Bus Station
      1:30 PM
      Florence, SC
      Bus Station
      0
      Greyhound US
      Economy
      $80
    Travel Time is 12h 5m shorter, and you will save $90

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 29h 45m 6:45 AM Madison, WI Chazen Museum 1:30 PM Florence, SC Bus Station  Economy $129
FlixBus 29h 30m 7:00 AM Madison, WI Dutch Mill Park & Ride 1:30 PM Florence, SC Bus Station  Economy $130
FlixBus 40h 50m 5:55 PM Madison, WI Chazen Museum 11:45 AM Florence, SC Bus Station  Economy $219
FlixBus 40h 35m 6:10 PM Madison, WI Dutch Mill Park & Ride 11:45 AM Florence, SC Bus Station  Economy $220

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 29h 30m 7:00 AM Madison, WI W Transfer Point 1:30 PM Florence, SC Bus Station  Economy $132
FlixBus 33h 40m 1:25 PM Madison, WI University Wisconsin-Madison 12:05 AM Florence, SC TA Travel Center  Economy $132
FlixBus 33h 20m 1:45 PM Madison, WI W Transfer Point 12:05 AM Florence, SC TA Travel Center  Economy $132
FlixBus 29h 45m 6:45 AM Madison, WI University Wisconsin-Madison 1:30 PM Florence, SC Bus Station  Economy $133
FlixBus 40h 50m 5:55 PM Madison, WI University Wisconsin-Madison 11:45 AM Florence, SC Bus Station  Economy $223

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 29h 30m 7:00 AM Madison, WI Dutch Mill Park & Ride 1:30 PM Florence, SC Bus Station  Economy $132
FlixBus 29h 45m 6:45 AM Madison, WI Chazen Museum 1:30 PM Florence, SC Bus Station  Economy $133
FlixBus 33h 40m 1:25 PM Madison, WI University Wisconsin-Madison 12:05 AM Florence, SC TA Travel Center  Economy $133
FlixBus 33h 20m 1:45 PM Madison, WI W Transfer Point 12:05 AM Florence, SC TA Travel Center  Economy $133
FlixBus 40h 50m 5:55 PM Madison, WI Chazen Museum 11:45 AM Florence, SC Bus Station  Economy $223

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 29h 30m 7:00 AM Madison, WI W Transfer Point 1:30 PM Florence, SC Bus Station  Economy $132
FlixBus 29h 45m 6:45 AM Madison, WI University Wisconsin-Madison 1:30 PM Florence, SC Bus Station  Economy $133
FlixBus 33h 40m 1:25 PM Madison, WI University Wisconsin-Madison 12:05 AM Florence, SC TA Travel Center  Economy $133
FlixBus 33h 20m 1:45 PM Madison, WI W Transfer Point 12:05 AM Florence, SC TA Travel Center  Economy $133
FlixBus 40h 50m 5:55 PM Madison, WI University Wisconsin-Madison 11:45 AM Florence, SC Bus Station  Economy $220

Best Price Offer: The price for the cheapest bus from Madison, WI to Florence, SC is $127 on 4/28/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Madison, WI and Florence, SC

See here how frequent the connections between Madison, WI and Florence, SC are, during different times and days of the week.
Saturday is the busiest day, with more than 12 daily buses from Madison, WI to Florence, SC. Wednesday has instead the fewest connections, with only 2 daily coaches between Madison, WI and Florence, SC.
The busiest time of the day is the Afternoon, with 19 buses from Madison, WI to Florence, SC, while Evening sees the fewest connections between Madison, WI and Florence, SC, with 9 offers.

Facts about the bus from Madison, WI to Florence, SC

Compare all providers like FlixBus that travel 6 times every day by bus from Madison, WI to Florence, SC in one click! Book your bus ticket from Madison, WI to Florence, SC starting from $127!

Cheapest Bus $127
Fastest Bus 30h 30m
Earliest Bus 6:45 AM
Latest Bus 6:10 PM
Daily Bus Routes 6 Ø
Distance 803.5 miles
Bus Companies FlixBus

Cheapest bus connections from Madison, WI to Florence, SC

Every day, 6 buses from 1 bus companies leave Madison, WI for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/19
Monday 04/20
$132
Tuesday 04/21
$131
Wednesday 04/22
$128
Thursday 04/23
$129
Friday 04/24
$132
Saturday 04/25
$133
Sunday 04/26
$132
Monday 04/27
$128
Tuesday 04/28
$127
Wednesday 04/29
Thursday 04/30
$132
Friday 05/01
$132
Saturday 05/02
$133
Sunday 05/03
$133
Monday 05/04
Tuesday 05/05
$131
Wednesday 05/06
Thursday 05/07
Friday 05/08
Saturday 05/09
Sunday 05/10
Monday 05/11
$131
Tuesday 05/12
$131
Wednesday 05/13
$130
Thursday 05/14
$133
Friday 05/15
Saturday 05/16

The cheapest time to travel from Madison, WI to Florence, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Madison, WI to Florence, SC, for the next 30 days.
With a price starting from $127, Tuesday is the cheapest day for a bus from Madison, WI to Florence, SC. Sunday instead is the most expensive day with prices starting from $132.
Morning is the cheapest day time for bus tickets from Madison, WI to Florence, SC, with $129. Evening is the most expensive time of the day with prices starting from $217.

How to save money travelling from Madison, WI to Florence, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Madison, WI to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madison, WI to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Madison, WI to Florence, SC are also emptier.

Beloved bus companies from Madison, WI to Florence, SC

These are the most booked bus companies between Madison, WI to Florence, SC from our users.

FlixBus from Madison, WI to Florence, SC

FlixBus

Here you will find the key facts about the FlixBus bus route Madison, WI to Florence, SC:

Cheapest Price $129
Fastest Bus 30h 30m
Earliest Bus 6:45 AM
Last Bus 6:10 PM
Daily Connections 6 Ø
Found on 3/26/2026

All bus stations and stops in Madison, WI and Florence, SC

In the map below, you can see where to find all bus stations in Madison, WI and Florence, SC.

Service and Comfort on the bus from Madison, WI to Florence, SC

Want to know which seat classes are available on the buses from Madison, WI to Florence, SC? Or which bus companies serve the route Madison, WI to Florence, SC? Below you will find answers to your questions.

FAQs about the Madison, WI to Florence, SC bus

How much does a Madison, WI Florence, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $127 and takes 30h 45m to reach Florence, SC. Compare offers to save money!

How much could I save by comparing buses from Madison, WI to Florence, SC?

This route is offered by 1 companies with a range of ticket prices between $127 and $228. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.

On average, how many connections are available from Madison, WI to Florence, SC each day?

Every day, the Madison, WI to Florence, SC bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Madison, WI to Florence, SC take?

The fastest bus from Madison, WI to Florence, SC is offered by FlixBus and takes 30h 30m. Bus tickets for this connection cost $132. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Madison, WI to Florence, SC?

The earliest bus arriving in Florence, SC from Madison, WI starts at 6:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Madison, WI to Florence, SC?

The latest bus trip departing from Madison, WI for Florence, SC starts at 6:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Madison, WI Florence, SC route?

When traveling by bus from Madison, WI to Florence, SC, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Madison, WI and Florence, SC?

You can check all the direct connections between Madison, WI and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Madison, WI to Florence, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Madison, WI Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Madison, WI Florence, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Madison, WI to Florence, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Madison, WI to Florence, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Madison, WI and Florence, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Madison, WI to Florence, SC?

Prices and availability for 6 trips between Madison, WI and Florence, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Madison, WI to Florence, SC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Madison, WI and to Florence, SC

Here’s an overview of the most popular bus routes to Madison, WI and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Madison, WI and to Florence, SC
CheckMyBus › Buses in USA › Bus to Madison, WI › Bus to Florence, SC

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