Compare all timetables for the bus from Jacksonville, FL to Florence, SC
Here is a selection of the cheapest bus trips from the schedule from Jacksonville, FL to Florence, SC from various bus operators like FlixBus for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 5h 10m | 8:15 AM | Jacksonville, FL | Amtrak Train Station | 1:25 PM | Florence, SC | Bus Station | Economy | $55 |
A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 2/7/2026 8:15:00 AM to Bus Station, Florence, SC (USA) arriving at 2/7/2026 1:25:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 5h 10m
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| FlixBus | 5h 35m | 6:30 PM | Jacksonville, FL | Amtrak Train Station | 12:05 AM | Florence, SC | TA Travel Center | Economy | $55 |
A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 2/7/2026 6:30:00 PM to TA Travel Center, Florence, SC (USA) arriving at 2/8/2026 12:05:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 5h 35m
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Best Price Offer: The price for the cheapest bus from Jacksonville, FL to Florence, SC is $54 on 2/1/2026. Flexible travelers save on ticket prices.
Facts about the bus from Jacksonville, FL to Florence, SC
Compare all providers like FlixBus that travel 2 times every day by bus from Jacksonville, FL to Florence, SC in one click! Book your bus ticket from Jacksonville, FL to Florence, SC starting from $54!
| Cheapest Bus | $54 |
| Fastest Bus | 5h 10m |
| Earliest Bus | 8:15 AM |
| Latest Bus | 6:30 PM |
| Daily Bus Routes | 2 Ø |
| Distance | 289.6 miles |
| Bus Companies | FlixBus |
Cheapest bus connections from Jacksonville, FL to Florence, SC
Every day, 2 buses from 1 bus companies leave Jacksonville, FL for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/06/2026 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
02/01
Monday
02/02
Tuesday
02/03
Wednesday
02/04
Thursday
02/05
Friday
02/06
Saturday
02/07
$55
Sunday
02/08
Monday
02/09
Tuesday
02/10
Wednesday
02/11
Thursday
02/12
Friday
02/13
Saturday
02/14
Sunday
02/15
Monday
02/16
Tuesday
02/17
Wednesday
02/18
Thursday
02/19
Friday
02/20
Saturday
02/21
Sunday
02/22
Monday
02/23
Tuesday
02/24
Wednesday
02/25
Thursday
02/26
Friday
02/27
Saturday
02/28
How to save money travelling from Jacksonville, FL to Florence, SC
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Jacksonville, FL to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Jacksonville, FL to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Jacksonville, FL to Florence, SC are also emptier.All bus stations and stops in Jacksonville, FL and Florence, SC
In the map below, you can see where to find all bus stations in Jacksonville, FL and Florence, SC.
Service and Comfort on the bus from Jacksonville, FL to Florence, SC
Want to know which seat classes are available on the buses from Jacksonville, FL to Florence, SC? Or which bus companies serve the route Jacksonville, FL to Florence, SC? Below you will find answers to your questions.
FAQs about the Jacksonville, FL to Florence, SC bus
How much does a Jacksonville, FL Florence, SC bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $54 and takes 5h 10m to reach Florence, SC. Compare offers to save money!
How much could I save by comparing buses from Jacksonville, FL to Florence, SC?
This route is offered by 1 companies with a range of ticket prices between $54 and $55. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.
On average, how many connections are available from Jacksonville, FL to Florence, SC each day?
Every day, the Jacksonville, FL to Florence, SC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Jacksonville, FL to Florence, SC take?
The fastest bus from Jacksonville, FL to Florence, SC is offered by FlixBus and takes 5h 10m. Bus tickets for this connection cost $55. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Jacksonville, FL to Florence, SC?
The earliest bus arriving in Florence, SC from Jacksonville, FL starts at 8:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Jacksonville, FL to Florence, SC?
The latest bus trip departing from Jacksonville, FL for Florence, SC starts at 6:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Jacksonville, FL Florence, SC route?
When traveling by bus from Jacksonville, FL to Florence, SC, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Jacksonville, FL and Florence, SC?
You can check all the direct connections between Jacksonville, FL and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.
What can I take with me on the Jacksonville, FL to Florence, SC bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Jacksonville, FL Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Jacksonville, FL Florence, SC bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Jacksonville, FL to Florence, SC on your planned travel date.
How does CheckMyBus find the best bus deals from Jacksonville, FL to Florence, SC?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Jacksonville, FL and Florence, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Jacksonville, FL to Florence, SC?
Prices and availability for 2 trips between Jacksonville, FL and Florence, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Jacksonville, FL to Florence, SC
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Jacksonville, FL and to Florence, SC
Here’s an overview of the most popular bus routes to Jacksonville, FL and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Jacksonville, FL
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- Charlotte to Jacksonville, FL bus
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- Buses from Georgetown, TX to Jacksonville, FL
- Bus to Jacksonville, FL from Jackson, MS
- From Knoxville, TN to Jacksonville, FL bus
- Buses to Jacksonville, FL from Memphis
- Bus Miami Beach, FL - Jacksonville, FL
- Buses Nashville - Jacksonville, FL
- Bus New Orleans, LA - Jacksonville, FL
- Buses Norfolk, VA - Jacksonville, FL
- Bus to Jacksonville, FL from North Charleston, SC
- Bus to Jacksonville, FL from Orlando, FL
- Bus to Jacksonville, FL from Portland, OR
- Buses Spring Hill, FL - Jacksonville, FL
- Buses to Jacksonville, FL from Tallahassee, FL
- Bus Routes to Florence, SC
- Bus to Florence, SC from Allentown, PA
- Bus from Atlanta, GA to Florence, SC
- From Charleston, SC to Florence, SC bus
- Bus to Florence, SC from Charlotte
- Buses to Florence, SC from Chicago
- Buses Dallas to Florence, SC
- Bus to Florence, SC from Lakeland, FL
- From Lewiston, ME to Florence, SC bus
- Madison, WI to Florence, SC bus
- From Manchester, TN to Florence, SC bus
- Buses Myrtle Beach, SC to Florence, SC
- Bus to Florence, SC from New York
- From Newark to Florence, SC bus
- Buses Providence, RI - Florence, SC
- Bus from Raleigh, NC to Florence, SC
- Buses to Florence, SC from Shreveport, LA
- Buses Washington, DC - Florence, SC
Popular Airport Shuttles to Jacksonville, FL and to Florence, SC
