Bus from Knoxville, TN to Jacksonville, FL from $132

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Knoxville, TN to Jacksonville, FL

Here is a selection of the cheapest bus trips from the schedule from Knoxville, TN to Jacksonville, FL from various bus operators like Greyhound US for the next days.

today
tomorrow
Sunday
$132
Monday
Tuesday
Wednesday
$144
Thursday

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 11h 20m 7:40 PM Knoxville, TN Greyhound Bus Station 7:00 AM Jacksonville, FL Amtrak Train Station  Economy $132
  • Did you know that if you travel from Knoxville, TN to Jacksonville, FL via Atlanta, GA, you can save more than $42? You can find the corresponding connections below.
    • FlixBus
      11h 20m
      0
      7:40 PM
      Knoxville, TN
      Greyhound Bus Station
      11:35 PM
      Atlanta, GA
      Garnett Transit Station
      0
      FlixBus
      Economy
      $36
      • Waiting Time 0h 50m
    • FlixBus
      6h 35m
      0
      12:25 AM
      Atlanta, GA
      Garnett Transit Station
      7:00 AM
      Jacksonville, FL
      Amtrak Train Station
      0
      FlixBus
      Economy
      $54
    Travel time is the same as the direct connection, but you will save $42

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 11h 20m 7:40 PM Knoxville, TN Greyhound Bus Station 7:00 AM Jacksonville, FL Amtrak Train Station  Economy $144
  • Did you know that if you travel from Knoxville, TN to Jacksonville, FL via Atlanta, GA, you can save more than $54? You can find the corresponding connections below.
    • FlixBus
      11h 20m
      0
      7:40 PM
      Knoxville, TN
      Greyhound Bus Station
      11:35 PM
      Atlanta, GA
      Garnett Transit Station
      0
      FlixBus
      Economy
      $36
      • Waiting Time 0h 50m
    • FlixBus
      6h 35m
      0
      12:25 AM
      Atlanta, GA
      Garnett Transit Station
      7:00 AM
      Jacksonville, FL
      Amtrak Train Station
      0
      FlixBus
      Economy
      $54
    Travel time is the same as the direct connection, but you will save $54

Best Price Offer: The price for the cheapest bus from Knoxville, TN to Jacksonville, FL is $132 on 2/8/2026. Flexible travelers save on ticket prices.


Facts about the bus from Knoxville, TN to Jacksonville, FL

Compare all providers like Greyhound US that travel 1 times every day by bus from Knoxville, TN to Jacksonville, FL in one click! Book your bus ticket from Knoxville, TN to Jacksonville, FL starting from $132!

Cheapest Bus $132
Fastest Bus 11h 20m
Earliest Bus 7:40 PM
Latest Bus 7:40 PM
Daily Bus Routes 1 Ø
Distance 410.5 miles
Bus Companies Greyhound US

Cheapest bus connections from Knoxville, TN to Jacksonville, FL

Every day, 1 buses from 1 bus companies leave Knoxville, TN for Jacksonville, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/06/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/01
Monday 02/02
Tuesday 02/03
Wednesday 02/04
Thursday 02/05
Friday 02/06
Saturday 02/07
Sunday 02/08
$132
Monday 02/09
Tuesday 02/10
Wednesday 02/11
$144
Thursday 02/12
Friday 02/13
Saturday 02/14
Sunday 02/15
Monday 02/16
Tuesday 02/17
Wednesday 02/18
Thursday 02/19
Friday 02/20
Saturday 02/21
Sunday 02/22
Monday 02/23
Tuesday 02/24
Wednesday 02/25
Thursday 02/26
Friday 02/27
Saturday 02/28

How to save money travelling from Knoxville, TN to Jacksonville, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Knoxville, TN to Jacksonville, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Knoxville, TN to Jacksonville, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Knoxville, TN to Jacksonville, FL are also emptier.

Beloved bus companies from Knoxville, TN to Jacksonville, FL

These are the most booked bus companies between Knoxville, TN to Jacksonville, FL from our users.

Greyhound US from Knoxville, TN to Jacksonville, FL

Greyhound US

Here you will find the key facts about the Greyhound US bus route Knoxville, TN to Jacksonville, FL:

Cheapest Price $132
Fastest Bus 11h 20m
Earliest Bus 7:40 PM
Last Bus 7:40 PM
Daily Connections 1 Ø
Found on 2/3/2026

All bus stations and stops in Knoxville, TN and Jacksonville, FL

In the map below, you can see where to find all bus stations in Knoxville, TN and Jacksonville, FL.

Service and Comfort on the bus from Knoxville, TN to Jacksonville, FL

Want to know which seat classes are available on the buses from Knoxville, TN to Jacksonville, FL? Or which bus companies serve the route Knoxville, TN to Jacksonville, FL? Below you will find answers to your questions.

FAQs about the Knoxville, TN to Jacksonville, FL bus

How much does a Knoxville, TN Jacksonville, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $132 and takes 11h 20m to reach Jacksonville, FL. Compare offers to save money!

How much could I save by comparing buses from Knoxville, TN to Jacksonville, FL?

This route is offered by 1 companies with a range of ticket prices between $132 and $144. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Jacksonville, FL.

On average, how many connections are available from Knoxville, TN to Jacksonville, FL each day?

Every day, the Knoxville, TN to Jacksonville, FL bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Knoxville, TN to Jacksonville, FL take?

The fastest bus from Knoxville, TN to Jacksonville, FL is offered by Greyhound US and takes 11h 20m. Bus tickets for this connection cost $132. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Knoxville, TN to Jacksonville, FL?

The earliest bus arriving in Jacksonville, FL from Knoxville, TN starts at 7:40 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Knoxville, TN to Jacksonville, FL?

The latest bus trip departing from Knoxville, TN for Jacksonville, FL starts at 7:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Knoxville, TN Jacksonville, FL route?

When traveling by bus from Knoxville, TN to Jacksonville, FL, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Knoxville, TN and Jacksonville, FL?

You can check all the direct connections between Knoxville, TN and Jacksonville, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Knoxville, TN to Jacksonville, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Knoxville, TN Jacksonville, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Knoxville, TN Jacksonville, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Knoxville, TN to Jacksonville, FL on your planned travel date.

How does CheckMyBus find the best bus deals from Knoxville, TN to Jacksonville, FL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Knoxville, TN and Jacksonville, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Knoxville, TN to Jacksonville, FL?

Prices and availability for 1 trips between Knoxville, TN and Jacksonville, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Knoxville, TN to Jacksonville, FL

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Knoxville, TN and to Jacksonville, FL

Here’s an overview of the most popular bus routes to Knoxville, TN and to Jacksonville, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses to Knoxville, TN from Rockledge, FL Buses to Knoxville, TN from Rockledge, FL
Bus Fort Pierce, FL - Knoxville, TN Bus Fort Pierce, FL - Knoxville, TN
Buses from Olympia, WA to Knoxville, TN Buses from Olympia, WA to Knoxville, TN
Buses Beaumont, TX to Knoxville, TN Buses Beaumont, TX to Knoxville, TN
Bus Panama City Beach, FL to Jacksonville, FL Bus Panama City Beach, FL to Jacksonville, FL
Buses Athens, TN - Jacksonville, FL Buses Athens, TN - Jacksonville, FL
Bus from Naples, FL to Jacksonville, FL Bus from Naples, FL to Jacksonville, FL
Fayetteville, NC to Jacksonville, FL bus Fayetteville, NC to Jacksonville, FL bus
Popular Airport Shuttles to Knoxville, TN and to Jacksonville, FL
CheckMyBus › Buses in USA › Bus to Knoxville, TN › Bus to Jacksonville, FL

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.