Which bus from Indianapolis to St. Louis, MO is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $33
Compare & Save Millions of buses in one click. Save up to 70%!
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Indianapolis to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Indianapolis to St. Louis, MO from various bus operators like Greyhound US for the next days.

today
$33
tomorrow
Saturday
$35
Sunday
Monday
$35
Tuesday
Wednesday
$40

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 3h 55m 3:30 AM Indianapolis Central Bus Station 6:25 AM St. Louis, MO Gateway Station  Economy $33
Greyhound US 4h 55m 11:25 AM Indianapolis Central Bus Station 3:20 PM St. Louis, MO Gateway Station  Economy $33
Greyhound US 4h 20m 8:05 PM Indianapolis Central Bus Station 11:25 PM St. Louis, MO Gateway Station  Economy $33

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 3h 55m 3:30 AM Indianapolis Central Bus Station 6:25 AM St. Louis, MO Gateway Station  Economy $35
Greyhound US 4h 55m 11:25 AM Indianapolis Central Bus Station 3:20 PM St. Louis, MO Gateway Station  Economy $35
Greyhound US 4h 20m 8:05 PM Indianapolis Central Bus Station 11:25 PM St. Louis, MO Gateway Station  Economy $35

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 3h 55m 3:30 AM Indianapolis Central Bus Station 6:25 AM St. Louis, MO Gateway Station  Economy $35
Greyhound US 4h 55m 11:25 AM Indianapolis Central Bus Station 3:20 PM St. Louis, MO Gateway Station  Economy $35
Greyhound US 4h 20m 8:05 PM Indianapolis Central Bus Station 11:25 PM St. Louis, MO Gateway Station  Economy $35

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 3h 55m 3:30 AM Indianapolis Central Bus Station 6:25 AM St. Louis, MO Gateway Station  Economy $40
Greyhound US 4h 55m 11:25 AM Indianapolis Central Bus Station 3:20 PM St. Louis, MO Gateway Station  Economy $40
Greyhound US 4h 20m 8:05 PM Indianapolis Central Bus Station 11:25 PM St. Louis, MO Gateway Station  Economy $40

Best Price Offer: The price for the cheapest bus from Indianapolis to St. Louis, MO is $33 on 12/4/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Indianapolis and St. Louis, MO

See here how frequent the connections between Indianapolis and St. Louis, MO are, during different times and days of the week.
Monday is the busiest day, with more than 6 daily buses from Indianapolis to St. Louis, MO. Wednesday has instead the fewest connections, with only 3 daily coaches between Indianapolis and St. Louis, MO.
The busiest time of the day is the Morning, with 7 buses from Indianapolis to St. Louis, MO, while Morning sees the fewest connections between Indianapolis and St. Louis, MO, with 7 offers.

Facts about the bus from Indianapolis to St. Louis, MO

Compare all providers like Greyhound US that travel 5 times every day by bus from Indianapolis to St. Louis, MO in one click! Book your bus ticket from Indianapolis to St. Louis, MO starting from $33!

Cheapest Bus $33
Fastest Bus 2h 55m
Earliest Bus 3:30 AM
Latest Bus 8:05 PM
Daily Bus Routes 5 Ø
Distance 230.8 miles
Bus Companies Greyhound US

Cheapest bus connections from Indianapolis to St. Louis, MO

Every day, 5 buses from 1 bus companies leave Indianapolis for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 11/30
Monday 12/01
Tuesday 12/02
Wednesday 12/03
Thursday 12/04
$33
Friday 12/05
Saturday 12/06
$35
Sunday 12/07
Monday 12/08
$35
Tuesday 12/09
Wednesday 12/10
$40
Thursday 12/11
Friday 12/12
Saturday 12/13
Sunday 12/14
Monday 12/15
$35
Tuesday 12/16
Wednesday 12/17
Thursday 12/18
Friday 12/19
Saturday 12/20
Sunday 12/21
Monday 12/22
Tuesday 12/23
Wednesday 12/24
Thursday 12/25
Friday 12/26
Saturday 12/27

The cheapest time to travel from Indianapolis to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Indianapolis to St. Louis, MO, for the next 30 days.
With a price starting from $33, Thursday is the cheapest day for a bus from Indianapolis to St. Louis, MO. Wednesday instead is the most expensive day with prices starting from $40.
Morning is the cheapest day time for bus tickets from Indianapolis to St. Louis, MO, with $33. Morning is the most expensive time of the day with prices starting from $33.

How to save money travelling from Indianapolis to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Indianapolis to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Indianapolis to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Indianapolis to St. Louis, MO are also emptier.

Beloved bus companies from Indianapolis to St. Louis, MO

These are the most booked bus companies between Indianapolis to St. Louis, MO from our users.

Greyhound US from Indianapolis to St. Louis, MO

Greyhound US

Here you will find the key facts about the Greyhound US bus route Indianapolis to St. Louis, MO:

Cheapest Price $33
Fastest Bus 2h 55m
Earliest Bus 3:30 AM
Last Bus 8:05 PM
Daily Connections 5 Ø
Found on 12/1/2025

All bus stations and stops in Indianapolis and St. Louis, MO

In the map below, you can see where to find all bus stations in Indianapolis and St. Louis, MO.

Service and Comfort on the bus from Indianapolis to St. Louis, MO

Want to know which seat classes are available on the buses from Indianapolis to St. Louis, MO? Or which bus companies serve the route Indianapolis to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Indianapolis to St. Louis, MO bus

How much does a Indianapolis St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $33 and takes 2h 55m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Indianapolis to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $33 and $40. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Indianapolis to St. Louis, MO each day?

Every day, the Indianapolis to St. Louis, MO bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Indianapolis to St. Louis, MO take?

The fastest bus from Indianapolis to St. Louis, MO is offered by Greyhound US and takes 2h 55m. Bus tickets for this connection cost $36. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Indianapolis to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Indianapolis starts at 3:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Indianapolis to St. Louis, MO?

The latest bus trip departing from Indianapolis for St. Louis, MO starts at 8:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Indianapolis St. Louis, MO route?

When traveling by bus from Indianapolis to St. Louis, MO, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Indianapolis and St. Louis, MO?

You can check all the direct connections between Indianapolis and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Indianapolis to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Indianapolis St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Indianapolis St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Indianapolis to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Indianapolis to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Indianapolis and to St. Louis, MO

Here’s an overview of the most popular bus routes to Indianapolis and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Miami to Indianapolis Bus Miami to Indianapolis
Bus Pittsburgh - Indianapolis Bus Pittsburgh - Indianapolis
Chicago to Indianapolis bus Chicago to Indianapolis bus
Bus New York to Indianapolis Bus New York to Indianapolis
Buses Houston to St. Louis, MO Buses Houston to St. Louis, MO
Bus Columbia, MO to St. Louis, MO Bus Columbia, MO to St. Louis, MO
Bus to St. Louis, MO from Chicago Bus to St. Louis, MO from Chicago
Buses Phoenix, AZ to St. Louis, MO Buses Phoenix, AZ to St. Louis, MO
Popular Airport Shuttles to Indianapolis and to St. Louis, MO
CheckMyBus › Buses in USA › Bus to Indianapolis › Bus to St. Louis, MO

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.