Bus Jacksonville, FL to Indianapolis: Compare prices and save money

Compare all timetables for the bus from Jacksonville, FL to Indianapolis

Here is a selection of the cheapest bus trips from the schedule from Jacksonville, FL to Indianapolis from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$106

Saturday

$112

Sunday

$112

Monday

$117

Tuesday

$93

Wednesday

$105

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 50m	9:05 AM	Jacksonville, FL	Downtown Bus Stop	4:55 AM	Indianapolis	Central Bus Station	Economy	$106	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/4/2026 9:05:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/5/2026 4:55:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 19h 50m
FlixBus	19h 20m	9:25 PM	Jacksonville, FL	Downtown Bus Stop	4:45 PM	Indianapolis	Central Bus Station	Economy	$106	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/4/2026 9:25:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/5/2026 4:45:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 19h 20m
Greyhound US	23h 30m	10:00 AM	Jacksonville, FL	Downtown Bus Stop	9:30 AM	Indianapolis	Central Bus Station	Economy	$106	A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/4/2026 10:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/5/2026 9:30:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 23h 30m
FlixBus	19h 40m	4:30 PM	Jacksonville, FL	Downtown Bus Stop	12:10 PM	Indianapolis	Central Bus Station	Economy	$108	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/4/2026 4:30:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/5/2026 12:10:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 19h 40m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 50m	9:05 AM	Jacksonville, FL	Downtown Bus Stop	4:55 AM	Indianapolis	Central Bus Station	Economy	$112	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/5/2026 9:05:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/6/2026 4:55:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 19h 50m
FlixBus	19h 40m	4:30 PM	Jacksonville, FL	Downtown Bus Stop	12:10 PM	Indianapolis	Central Bus Station	Economy	$112	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/5/2026 4:30:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/6/2026 12:10:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 19h 40m
FlixBus	19h 20m	9:25 PM	Jacksonville, FL	Downtown Bus Stop	4:45 PM	Indianapolis	Central Bus Station	Economy	$112	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/5/2026 9:25:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/6/2026 4:45:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 19h 20m
Greyhound US	23h 30m	10:00 AM	Jacksonville, FL	Downtown Bus Stop	9:30 AM	Indianapolis	Central Bus Station	Economy	$113	A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/5/2026 10:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/6/2026 9:30:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 23h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 50m	9:05 AM	Jacksonville, FL	Downtown Bus Stop	4:55 AM	Indianapolis	Central Bus Station	Economy	$112	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/6/2026 9:05:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/7/2026 4:55:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 19h 50m
FlixBus	19h 40m	4:30 PM	Jacksonville, FL	Downtown Bus Stop	12:10 PM	Indianapolis	Central Bus Station	Economy	$112	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/6/2026 4:30:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/7/2026 12:10:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 19h 40m
FlixBus	19h 20m	9:25 PM	Jacksonville, FL	Downtown Bus Stop	4:45 PM	Indianapolis	Central Bus Station	Economy	$112	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/6/2026 9:25:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/7/2026 4:45:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 19h 20m
Greyhound US	23h 30m	10:00 AM	Jacksonville, FL	Downtown Bus Stop	9:30 AM	Indianapolis	Central Bus Station	Economy	$113	A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/6/2026 10:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/7/2026 9:30:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 23h 30m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	23h 30m	10:00 AM	Jacksonville, FL	Downtown Bus Stop	9:30 AM	Indianapolis	Central Bus Station	Economy	$117	A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/7/2026 10:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/8/2026 9:30:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 23h 30m
FlixBus	19h 40m	4:30 PM	Jacksonville, FL	Downtown Bus Stop	12:10 PM	Indianapolis	Central Bus Station	Economy	$118	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/7/2026 4:30:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/8/2026 12:10:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 19h 40m
FlixBus	19h 20m	9:25 PM	Jacksonville, FL	Downtown Bus Stop	4:45 PM	Indianapolis	Central Bus Station	Economy	$118	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/7/2026 9:25:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/8/2026 4:45:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 19h 20m
FlixBus	29h 40m	11:15 PM	Jacksonville, FL	Downtown Bus Stop	4:55 AM	Indianapolis	Central Bus Station	Economy	$129	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/7/2026 11:15:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/9/2026 4:55:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 29h 40m

Did you know that if you travel from Jacksonville, FL to Indianapolis via Atlanta, GA, you can save more than $13? You can find the corresponding connections below.
- Greyhound US
  
  24h 0m
  
  0
  
  9:30 AM
  
  Jacksonville, FL
  Amtrak Train Station
  
  6:15 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $47
  
  A Bus from Greyhound US goes from Amtrak Train Station, Jacksonville, FL (USA) at 9/9/2026 9:30:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 9/9/2026 6:15:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 45m
- Greyhound US
  
  11h 50m
  
  0
  
  9:40 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  9:30 AM
  
  Indianapolis
  Central Bus Station
  
  0
  
  Economy
  
  $57
  
  A Bus from Greyhound US goes from Garnett Transit Station, Atlanta, GA (USA) at 9/9/2026 9:40:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/10/2026 9:30:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 11h 50m
Travel time is 4h 40m longer, but you will save $13

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 20m	9:25 PM	Jacksonville, FL	Downtown Bus Stop	4:45 PM	Indianapolis	Central Bus Station	Economy	$93	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/8/2026 9:25:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/9/2026 4:45:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 19h 20m
Greyhound US	23h 30m	10:00 AM	Jacksonville, FL	Downtown Bus Stop	9:30 AM	Indianapolis	Central Bus Station	Economy	$93	A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/8/2026 10:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/9/2026 9:30:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 23h 30m
FlixBus	19h 50m	9:05 AM	Jacksonville, FL	Downtown Bus Stop	4:55 AM	Indianapolis	Central Bus Station	Economy	$100	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/8/2026 9:05:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/9/2026 4:55:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 19h 50m
FlixBus	29h 40m	11:15 PM	Jacksonville, FL	Downtown Bus Stop	4:55 AM	Indianapolis	Central Bus Station	Economy	$113	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/8/2026 11:15:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/10/2026 4:55:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 29h 40m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	23h 30m	10:00 AM	Jacksonville, FL	Downtown Bus Stop	9:30 AM	Indianapolis	Central Bus Station	Economy	$105	A Bus from Greyhound US goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/9/2026 10:00:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/10/2026 9:30:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 23h 30m
FlixBus	19h 40m	4:30 PM	Jacksonville, FL	Downtown Bus Stop	12:10 PM	Indianapolis	Central Bus Station	Economy	$106	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/9/2026 4:30:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/10/2026 12:10:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 19h 40m
FlixBus	19h 20m	9:25 PM	Jacksonville, FL	Downtown Bus Stop	4:45 PM	Indianapolis	Central Bus Station	Economy	$106	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/9/2026 9:25:00 PM to Central Bus Station, Indianapolis (USA) arriving at 9/10/2026 4:45:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 19h 20m
FlixBus	19h 50m	9:05 AM	Jacksonville, FL	Downtown Bus Stop	4:55 AM	Indianapolis	Central Bus Station	Economy	$110	A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/9/2026 9:05:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/10/2026 4:55:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 19h 50m

Did you know that if you travel from Jacksonville, FL to Indianapolis via Atlanta, GA, you can save more than $14? You can find the corresponding connections below.
- FlixBus
  
  19h 20m
  
  0
  
  9:25 PM
  
  Jacksonville, FL
  Downtown Bus Stop
  
  4:10 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $39
  
  A Bus from FlixBus goes from Downtown Bus Stop, Jacksonville, FL (USA) at 9/10/2026 9:25:00 PM to Garnett Transit Station, Atlanta, GA (USA) arriving at 9/11/2026 4:10:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 6h 45m
- Greyhound US
  
  11h 55m
  
  0
  
  4:50 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  4:45 PM
  
  Indianapolis
  Central Bus Station
  
  0
  
  Economy
  
  $52
  
  A Bus from Greyhound US goes from Garnett Transit Station, Atlanta, GA (USA) at 9/11/2026 4:50:00 AM to Central Bus Station, Indianapolis (USA) arriving at 9/11/2026 4:45:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 11h 55m
Travel time is the same as the direct connection, but you will save $14

Best Price Offer: The price for the cheapest bus from Jacksonville, FL to Indianapolis is $85 on 9/23/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Jacksonville, FL and Indianapolis

See here how frequent the connections between Jacksonville, FL and Indianapolis are, during different times and days of the week.

Sunday is the busiest day, with more than 5 daily buses from Jacksonville, FL to Indianapolis. Tuesday has instead the fewest connections, with only 4 daily coaches between Jacksonville, FL and Indianapolis.

The busiest time of the day is the Morning, with 12 buses from Jacksonville, FL to Indianapolis, while Afternoon sees the fewest connections between Jacksonville, FL and Indianapolis, with 5 offers.

Facts about the bus from Jacksonville, FL to Indianapolis

Compare all providers like FlixBus and Greyhound US that travel 4 times every day by bus from Jacksonville, FL to Indianapolis in one click! Book your bus ticket from Jacksonville, FL to Indianapolis starting from $85!

Cheapest Bus	$85
Fastest Bus	19h 20m
Earliest Bus	9:05 AM
Latest Bus	9:25 PM
Daily Bus Routes	4 Ø
Distance	699.6 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Jacksonville, FL to Indianapolis

Every day, 4 buses from 2 bus companies leave Jacksonville, FL for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/03/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/30

Monday 08/31

Tuesday 09/01

Wednesday 09/02

Thursday 09/03

Friday 09/04

$106

Saturday 09/05

$112

Sunday 09/06

$112

Monday 09/07

$117

Tuesday 09/08

$93

Wednesday 09/09

$105

Thursday 09/10

$100

Friday 09/11

$100

Saturday 09/12

$109

Sunday 09/13

Monday 09/14

Tuesday 09/15

$86

Wednesday 09/16

$96

Thursday 09/17

$109

Friday 09/18

$107

Saturday 09/19

Sunday 09/20

$112

Monday 09/21

Tuesday 09/22

$99

Wednesday 09/23

$85

Thursday 09/24

Friday 09/25

$92

Saturday 09/26

The cheapest time to travel from Jacksonville, FL to Indianapolis

See here on which day and which time of the day you can find the cheapest bus ticket from Jacksonville, FL to Indianapolis, for the next 30 days.

With a price starting from $85, Wednesday is the cheapest day for a bus from Jacksonville, FL to Indianapolis. Sunday instead is the most expensive day with prices starting from $100.

Morning is the cheapest day time for bus tickets from Jacksonville, FL to Indianapolis, with $93. Afternoon is the most expensive time of the day with prices starting from $106.

How to save money travelling from Jacksonville, FL to Indianapolis

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Jacksonville, FL to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Jacksonville, FL to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Jacksonville, FL to Indianapolis are also emptier.

Beloved bus companies from Jacksonville, FL to Indianapolis

These are the most booked bus companies between Jacksonville, FL to Indianapolis from our users.

FlixBus from Jacksonville, FL to Indianapolis

Here you will find the key facts about the FlixBus bus route Jacksonville, FL to Indianapolis:

Cheapest Price	$93
Fastest Bus	19h 20m
Earliest Bus	9:05 AM
Last Bus	9:25 PM
Daily Connections	3 Ø
Found on	8/10/2026

Greyhound US from Jacksonville, FL to Indianapolis

Here you will find the key facts about the Greyhound US bus route Jacksonville, FL to Indianapolis:

Cheapest Price	$93
Fastest Bus	23h 30m
Earliest Bus	10:00 AM
Last Bus	10:00 AM
Daily Connections	1 Ø
Found on	8/10/2026

All bus stations and stops in Jacksonville, FL and Indianapolis

In the map below, you can see where to find all bus stations in Jacksonville, FL and Indianapolis.

Downtown Bus Stop

West Forsyth Street 1111

Beaver St. & Ocean St. Bus Stop

Central Bus Station

Old St. Augustine Rd

Old St. Augustine Rd 10584-13

Southpoint Bus Stop

Mile Square

Monument Circle 2250

Washington / Delaware

E Washington St between N Delaware St and N Alabama St

Central Bus Station

Greyhound Bus Station

S Illinois St 350

S Keystone Avenue

S Keystone Avenue 3649

Service and Comfort on the bus from Jacksonville, FL to Indianapolis

Want to know which seat classes are available on the buses from Jacksonville, FL to Indianapolis? Or which bus companies serve the route Jacksonville, FL to Indianapolis? Below you will find answers to your questions.

FAQs about the Jacksonville, FL to Indianapolis bus

How much does a Jacksonville, FL Indianapolis bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $85 and takes 23h 30m to reach Indianapolis. Compare offers to save money!

How much could I save by comparing buses from Jacksonville, FL to Indianapolis?

This route is offered by 2 companies with a range of ticket prices between $85 and $160. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.

On average, how many connections are available from Jacksonville, FL to Indianapolis each day?

Every day, the Jacksonville, FL to Indianapolis bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Jacksonville, FL to Indianapolis take?

The fastest bus from Jacksonville, FL to Indianapolis is offered by FlixBus and takes 19h 20m. Bus tickets for this connection cost $106. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Jacksonville, FL to Indianapolis?

The earliest bus arriving in Indianapolis from Jacksonville, FL starts at 9:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Jacksonville, FL to Indianapolis?

The latest bus trip departing from Jacksonville, FL for Indianapolis starts at 9:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Jacksonville, FL Indianapolis route?

When traveling by bus from Jacksonville, FL to Indianapolis, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Jacksonville, FL and Indianapolis?

You can check all the direct connections between Jacksonville, FL and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Jacksonville, FL to Indianapolis bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Jacksonville, FL Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Jacksonville, FL Indianapolis bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Jacksonville, FL to Indianapolis on your planned travel date.

How does CheckMyBus find the best bus deals from Jacksonville, FL to Indianapolis?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Jacksonville, FL and Indianapolis. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Jacksonville, FL to Indianapolis?

Prices and availability for 4 trips between Jacksonville, FL and Indianapolis change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Jacksonville, FL to Indianapolis

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Jacksonville, FL and to Indianapolis

Here’s an overview of the most popular bus routes to Jacksonville, FL and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!