Bus from Tallahassee, FL to St. Louis, MO from $113

Compare all the bus companies and find the best price with CheckMyBus
Compare & Save Millions of buses in one click. Save up to 70%!
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Tallahassee, FL to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Tallahassee, FL to St. Louis, MO from various bus operators like Greyhound US or FlixBus for the next days.

today
tomorrow
Saturday
$124
Sunday
Monday
Tuesday
Wednesday
$125

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 23h 5m 5:40 PM Tallahassee, FL Greyhound Bus Station 3:45 PM St. Louis, MO Gateway Station  Economy $124
FlixBus 19h 0m 3:10 PM Tallahassee, FL Greyhound Bus Station 9:10 AM St. Louis, MO Gateway Station  Economy $125
Greyhound US 27h 35m 8:25 PM Tallahassee, FL Greyhound Bus Station 11:00 PM St. Louis, MO Gateway Station  Economy $125
  • Did you know that if you travel from Tallahassee, FL to St. Louis, MO via Atlanta, GA, you can save more than $25? You can find the corresponding connections below.
    • Busbud
      21h 20m
      0
      12:50 PM
      Tallahassee, FL
      Greyhound Bus Station
      7:40 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $39
      • Waiting Time 3h 50m
    • Busbud
      10h 40m
      0
      11:30 PM
      Atlanta, GA
      Garnett Transit Station
      9:10 AM
      St. Louis, MO
      Gateway Station
      0
      Busbud
      Economy
      $60
    Travel time is 3h 20m longer, but you will save $25

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 27h 35m 8:25 PM Tallahassee, FL Greyhound Bus Station 11:00 PM St. Louis, MO Gateway Station  Economy $125
Greyhound US 23h 15m 5:40 PM Tallahassee, FL Greyhound Bus Station 3:55 PM St. Louis, MO Gateway Station  Economy $126
FlixBus 19h 0m 3:10 PM Tallahassee, FL Greyhound Bus Station 9:10 AM St. Louis, MO Gateway Station  Economy $144
  • Did you know that if you travel from Tallahassee, FL to St. Louis, MO via Atlanta, GA, you can save more than $26? You can find the corresponding connections below.
    • Busbud
      21h 20m
      0
      12:50 PM
      Tallahassee, FL
      Greyhound Bus Station
      7:40 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $39
      • Waiting Time 3h 50m
    • Busbud
      10h 40m
      0
      11:30 PM
      Atlanta, GA
      Garnett Transit Station
      9:10 AM
      St. Louis, MO
      Gateway Station
      0
      Busbud
      Economy
      $60
    Travel time is 3h 20m longer, but you will save $26

Best Price Offer: The price for the cheapest bus from Tallahassee, FL to St. Louis, MO is $113 on 12/16/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Tallahassee, FL and St. Louis, MO

See here how frequent the connections between Tallahassee, FL and St. Louis, MO are, during different times and days of the week.
Wednesday is the busiest day, with more than 3 daily buses from Tallahassee, FL to St. Louis, MO. Wednesday has instead the fewest connections, with only 3 daily coaches between Tallahassee, FL and St. Louis, MO.
The busiest time of the day is the Afternoon, with 4 buses from Tallahassee, FL to St. Louis, MO, while Evening sees the fewest connections between Tallahassee, FL and St. Louis, MO, with 2 offers.

Facts about the bus from Tallahassee, FL to St. Louis, MO

Compare all providers like Greyhound US and FlixBus that travel 3 times every day by bus from Tallahassee, FL to St. Louis, MO in one click! Book your bus ticket from Tallahassee, FL to St. Louis, MO starting from $113!

Cheapest Bus $113
Fastest Bus 18h 0m
Earliest Bus 3:10 PM
Latest Bus 8:25 PM
Daily Bus Routes 3 Ø
Distance 657.9 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from Tallahassee, FL to St. Louis, MO

Every day, 3 buses from 2 bus companies leave Tallahassee, FL for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 11/30
Monday 12/01
Tuesday 12/02
Wednesday 12/03
Thursday 12/04
Friday 12/05
Saturday 12/06
$124
Sunday 12/07
Monday 12/08
Tuesday 12/09
Wednesday 12/10
$125
Thursday 12/11
Friday 12/12
Saturday 12/13
Sunday 12/14
Monday 12/15
Tuesday 12/16
$113
Wednesday 12/17
Thursday 12/18
Friday 12/19
Saturday 12/20
Sunday 12/21
Monday 12/22
Tuesday 12/23
Wednesday 12/24
Thursday 12/25
Friday 12/26
Saturday 12/27

The cheapest time to travel from Tallahassee, FL to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Tallahassee, FL to St. Louis, MO, for the next 30 days.
With a price starting from $124, Saturday is the cheapest day for a bus from Tallahassee, FL to St. Louis, MO. Wednesday instead is the most expensive day with prices starting from $125.
Evening is the cheapest day time for bus tickets from Tallahassee, FL to St. Louis, MO, with $124. Afternoon is the most expensive time of the day with prices starting from $124.

How to save money travelling from Tallahassee, FL to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tallahassee, FL to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tallahassee, FL to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tallahassee, FL to St. Louis, MO are also emptier.

All bus stations and stops in Tallahassee, FL and St. Louis, MO

In the map below, you can see where to find all bus stations in Tallahassee, FL and St. Louis, MO.

Service and Comfort on the bus from Tallahassee, FL to St. Louis, MO

Want to know which seat classes are available on the buses from Tallahassee, FL to St. Louis, MO? Or which bus companies serve the route Tallahassee, FL to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Tallahassee, FL to St. Louis, MO bus

How much does a Tallahassee, FL St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $113 and takes 22h 5m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Tallahassee, FL to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $113 and $144. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Tallahassee, FL to St. Louis, MO each day?

Every day, the Tallahassee, FL to St. Louis, MO bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tallahassee, FL to St. Louis, MO take?

The fastest bus from Tallahassee, FL to St. Louis, MO is offered by FlixBus and takes 18h 0m. Bus tickets for this connection cost $125. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tallahassee, FL to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Tallahassee, FL starts at 3:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tallahassee, FL to St. Louis, MO?

The latest bus trip departing from Tallahassee, FL for St. Louis, MO starts at 8:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tallahassee, FL St. Louis, MO route?

When traveling by bus from Tallahassee, FL to St. Louis, MO, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tallahassee, FL and St. Louis, MO?

You can check all the direct connections between Tallahassee, FL and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Tallahassee, FL to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tallahassee, FL St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tallahassee, FL St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tallahassee, FL to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Tallahassee, FL to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tallahassee, FL and to St. Louis, MO

Here’s an overview of the most popular bus routes to Tallahassee, FL and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from West Palm Beach, FL to Tallahassee, FL Bus from West Palm Beach, FL to Tallahassee, FL
Bus to Tallahassee, FL from Dothan, AL Bus to Tallahassee, FL from Dothan, AL
Buses Dallas - Tallahassee, FL Buses Dallas - Tallahassee, FL
Buses from New York to Tallahassee, FL Buses from New York to Tallahassee, FL
Bus New Orleans, LA to St. Louis, MO Bus New Orleans, LA to St. Louis, MO
Cleveland to St. Louis, MO bus Cleveland to St. Louis, MO bus
Buses from Kansas City to St. Louis, MO Buses from Kansas City to St. Louis, MO
Bus Atlanta, GA - St. Louis, MO Bus Atlanta, GA - St. Louis, MO
Popular Airport Shuttles to Tallahassee, FL and to St. Louis, MO
CheckMyBus › Buses in USA › Bus to Tallahassee, FL › Bus to St. Louis, MO

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.