Which bus from Cleveland to St. Louis, MO is the cheapest?

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Compare all timetables for the bus from Cleveland to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Cleveland to St. Louis, MO from various bus operators like Greyhound US or FlixBus for the next days.

today
$91
tomorrow
$89
Monday
$84
Tuesday
$97
Wednesday
$88
Thursday
$91
Friday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 16h 55m 4:00 PM Cleveland Greyhound Bus Station 7:55 AM St. Louis, MO Gateway Station  Economy $91
Greyhound US 19h 50m 11:35 AM Cleveland Greyhound Bus Station 6:25 AM St. Louis, MO Gateway Station  Economy $92
  • Did you know that if you travel from Cleveland to St. Louis, MO via Indianapolis, you can save more than $11? You can find the corresponding connections below.
    • FlixBus
      16h 50m
      0
      7:30 AM
      Cleveland
      Greyhound Bus Station
      6:50 PM
      Indianapolis
      Central Bus Station
      0
      FlixBus
      Economy
      $44
      • Waiting Time 1h 15m
    • Greyhound US
      4h 15m
      0
      8:05 PM
      Indianapolis
      Central Bus Station
      11:20 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $36
    Travel time is 0h 55m longer, but you will save $11

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 19h 50m 11:35 AM Cleveland Greyhound Bus Station 6:25 AM St. Louis, MO Gateway Station  Economy $89
Greyhound US 16h 55m 4:00 PM Cleveland Greyhound Bus Station 7:55 AM St. Louis, MO Gateway Station  Economy $89
FlixBus 16h 50m 7:30 AM Cleveland Greyhound Bus Station 11:20 PM St. Louis, MO Gateway Station  Economy $90
  • Did you know that if you travel from Cleveland to St. Louis, MO via Indianapolis, you can save more than $13? You can find the corresponding connections below.
    • Greyhound US
      16h 55m
      0
      4:00 PM
      Cleveland
      Greyhound Bus Station
      4:10 AM
      Indianapolis
      Central Bus Station
      0
      Greyhound US
      Economy
      $44
      • Waiting Time 0h 50m
    • Greyhound US
      3h 55m
      0
      5:00 AM
      Indianapolis
      Central Bus Station
      7:55 AM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $32
    Travel time is 1h 5m longer, but you will save $13

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 19h 50m 11:35 AM Cleveland Greyhound Bus Station 6:25 AM St. Louis, MO Gateway Station  Economy $84
FlixBus 16h 50m 7:30 AM Cleveland Greyhound Bus Station 11:20 PM St. Louis, MO Gateway Station  Economy $85
Greyhound US 16h 55m 4:00 PM Cleveland Greyhound Bus Station 7:55 AM St. Louis, MO Gateway Station  Economy $85
  • Did you know that if you travel from Cleveland to St. Louis, MO via Columbus, OH, you can save more than $11? You can find the corresponding connections below.
    • Greyhound US
      21h 35m
      0
      2:45 AM
      Cleveland
      Greyhound Bus Station
      5:25 AM
      Columbus, OH
      E Main St & S Lazelle St
      0
      Greyhound US
      Economy
      $23
      • Waiting Time 9h 5m
    • Greyhound US
      9h 50m
      0
      2:30 PM
      Columbus, OH
      E Main St & S Lazelle St
      11:20 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $50
    Travel time is 5h 45m longer, but you will save $11

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 19h 50m 11:35 AM Cleveland Greyhound Bus Station 6:25 AM St. Louis, MO Gateway Station  Economy $97
FlixBus 17h 15m 7:30 AM Cleveland Greyhound Bus Station 11:45 PM St. Louis, MO Gateway Station  Economy $99
Greyhound US 16h 55m 4:00 PM Cleveland Greyhound Bus Station 7:55 AM St. Louis, MO Gateway Station  Economy $102
Greyhound US 19h 0m 12:25 PM Cleveland Greyhound Bus Station 6:25 AM St. Louis, MO Gateway Station  Economy $103
  • Did you know that if you travel from Cleveland to St. Louis, MO via Columbus, OH, you can save more than $24? You can find the corresponding connections below.
    • Greyhound US
      21h 35m
      0
      2:45 AM
      Cleveland
      Greyhound Bus Station
      5:25 AM
      Columbus, OH
      E Main St & S Lazelle St
      0
      Greyhound US
      Economy
      $23
      • Waiting Time 9h 5m
    • Greyhound US
      9h 50m
      0
      2:30 PM
      Columbus, OH
      E Main St & S Lazelle St
      11:20 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $50
    Travel time is 5h 40m longer, but you will save $24

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 19h 55m 4:25 AM Cleveland Greyhound Bus Station 11:20 PM St. Louis, MO Gateway Station  Economy $88
Greyhound US 19h 50m 11:35 AM Cleveland Greyhound Bus Station 6:25 AM St. Louis, MO Gateway Station  Economy $88
Greyhound US 16h 55m 4:00 PM Cleveland Greyhound Bus Station 7:55 AM St. Louis, MO Gateway Station  Economy $89
  • Did you know that if you travel from Cleveland to St. Louis, MO via Columbus, OH, you can save more than $15? You can find the corresponding connections below.
    • Greyhound US
      21h 35m
      0
      2:45 AM
      Cleveland
      Greyhound Bus Station
      5:25 AM
      Columbus, OH
      E Main St & S Lazelle St
      0
      Greyhound US
      Economy
      $23
      • Waiting Time 9h 5m
    • Greyhound US
      9h 50m
      0
      2:30 PM
      Columbus, OH
      E Main St & S Lazelle St
      11:20 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $50
    Travel time is 5h 40m longer, but you will save $15

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 20h 20m 4:25 AM Cleveland Greyhound Bus Station 11:45 PM St. Louis, MO Gateway Station  Economy $91
Greyhound US 19h 50m 11:35 AM Cleveland Greyhound Bus Station 6:25 AM St. Louis, MO Gateway Station  Economy $91
Greyhound US 16h 55m 4:00 PM Cleveland Greyhound Bus Station 7:55 AM St. Louis, MO Gateway Station  Economy $91
Greyhound US 16h 25m 4:30 PM Cleveland Greyhound Bus Station 7:55 AM St. Louis, MO Gateway Station  Economy $100
Greyhound US 19h 0m 12:25 PM Cleveland Greyhound Bus Station 6:25 AM St. Louis, MO Gateway Station  Economy $104
  • Did you know that if you travel from Cleveland to St. Louis, MO via Columbus, OH, you can save more than $18? You can find the corresponding connections below.
    • Greyhound US
      21h 35m
      0
      2:45 AM
      Cleveland
      Greyhound Bus Station
      5:25 AM
      Columbus, OH
      E Main St & S Lazelle St
      0
      Greyhound US
      Economy
      $23
      • Waiting Time 9h 5m
    • Greyhound US
      9h 50m
      0
      2:30 PM
      Columbus, OH
      E Main St & S Lazelle St
      11:20 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $50
    Travel time is 6h 10m longer, but you will save $18

Best Price Offer: The price for the cheapest bus from Cleveland to St. Louis, MO is $74 on 4/10/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Cleveland and St. Louis, MO

See here how frequent the connections between Cleveland and St. Louis, MO are, during different times and days of the week.
Tuesday is the busiest day, with more than 6 daily buses from Cleveland to St. Louis, MO. Saturday has instead the fewest connections, with only 2 daily coaches between Cleveland and St. Louis, MO.
The busiest time of the day is the Afternoon, with 10 buses from Cleveland to St. Louis, MO, while Night sees the fewest connections between Cleveland and St. Louis, MO, with 4 offers.

Facts about the bus from Cleveland to St. Louis, MO

Compare all providers like Greyhound US and FlixBus that travel 3 times every day by bus from Cleveland to St. Louis, MO in one click! Book your bus ticket from Cleveland to St. Louis, MO starting from $74!

Cheapest Bus $74
Fastest Bus 15h 25m
Earliest Bus 11:35 AM
Latest Bus 4:30 PM
Daily Bus Routes 3 Ø
Distance 492.7 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from Cleveland to St. Louis, MO

Every day, 3 buses from 2 bus companies leave Cleveland for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/11/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/05
Monday 04/06
Tuesday 04/07
Wednesday 04/08
Thursday 04/09
Friday 04/10
Saturday 04/11
$91
Sunday 04/12
$89
Monday 04/13
$84
Tuesday 04/14
$97
Wednesday 04/15
$88
Thursday 04/16
$91
Friday 04/17
Saturday 04/18
$86
Sunday 04/19
$89
Monday 04/20
$79
Tuesday 04/21
$81
Wednesday 04/22
$79
Thursday 04/23
$81
Friday 04/24
$85
Saturday 04/25
Sunday 04/26
$90
Monday 04/27
$80
Tuesday 04/28
$77
Wednesday 04/29
$82
Thursday 04/30
Friday 05/01
$75
Saturday 05/02

The cheapest time to travel from Cleveland to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Cleveland to St. Louis, MO, for the next 30 days.
With a price starting from $76, Monday is the cheapest day for a bus from Cleveland to St. Louis, MO. Saturday instead is the most expensive day with prices starting from $86.
Night is the cheapest day time for bus tickets from Cleveland to St. Louis, MO, with $75. Afternoon is the most expensive time of the day with prices starting from $85.

How to save money travelling from Cleveland to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Cleveland to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Cleveland to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Cleveland to St. Louis, MO are also emptier.

Beloved bus companies from Cleveland to St. Louis, MO

These are the most booked bus companies between Cleveland to St. Louis, MO from our users.

Greyhound US from Cleveland to St. Louis, MO

Greyhound US

Here you will find the key facts about the Greyhound US bus route Cleveland to St. Louis, MO:

Cheapest Price $84
Fastest Bus 15h 25m
Earliest Bus 11:35 AM
Last Bus 4:30 PM
Daily Connections 3 Ø
Found on 4/9/2026

FlixBus from Cleveland to St. Louis, MO

FlixBus

Here you will find the key facts about the FlixBus bus route Cleveland to St. Louis, MO:

Cheapest Price $85
Fastest Bus 15h 50m
Earliest Bus 7:30 AM
Last Bus 7:30 AM
Daily Connections 1 Ø
Found on 4/9/2026

All bus stations and stops in Cleveland and St. Louis, MO

In the map below, you can see where to find all bus stations in Cleveland and St. Louis, MO.

Service and Comfort on the bus from Cleveland to St. Louis, MO

Want to know which seat classes are available on the buses from Cleveland to St. Louis, MO? Or which bus companies serve the route Cleveland to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Cleveland to St. Louis, MO bus

How much does a Cleveland St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $74 and takes 18h 50m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Cleveland to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $74 and $119. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Cleveland to St. Louis, MO each day?

Every day, the Cleveland to St. Louis, MO bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Cleveland to St. Louis, MO take?

The fastest bus from Cleveland to St. Louis, MO is offered by Greyhound US and takes 15h 25m. Bus tickets for this connection cost $105. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Cleveland to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Cleveland starts at 11:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Cleveland to St. Louis, MO?

The latest bus trip departing from Cleveland for St. Louis, MO starts at 4:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Cleveland St. Louis, MO route?

When traveling by bus from Cleveland to St. Louis, MO, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Cleveland and St. Louis, MO?

You can check all the direct connections between Cleveland and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Cleveland to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Cleveland St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Cleveland St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Cleveland to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Cleveland to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Cleveland and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Cleveland to St. Louis, MO?

Prices and availability for 3 trips between Cleveland and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Cleveland to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Cleveland and to St. Louis, MO

Here’s an overview of the most popular bus routes to Cleveland and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Cleveland and to St. Louis, MO
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