Bus from Pittsburgh to St. Louis, MO from $75

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Compare all timetables for the bus from Pittsburgh to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Pittsburgh to St. Louis, MO from various bus operators like Greyhound US for the next days.
today
tomorrow
Tuesday
from $75
Wednesday
Thursday
from $79
Friday
from $75
Saturday
from $77

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    13h 45m
    0
    1:35 AM
    Pittsburgh
    Grant Street Transportation Center
    3:20 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $75
  • Greyhound US
    12h 45m
    0
    10:50 AM
    Pittsburgh
    Grant Street Transportation Center
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $75
  • Greyhound US
    11h 55m
    0
    6:30 PM
    Pittsburgh
    Grant Street Transportation Center
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $75

Cheapest bus trips Thursday

Prices are for one way and one person
  • Greyhound US
    13h 45m
    0
    1:35 AM
    Pittsburgh
    Grant Street Transportation Center
    3:20 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $79
  • Greyhound US
    11h 55m
    0
    6:30 PM
    Pittsburgh
    Grant Street Transportation Center
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $79
  • Greyhound US
    12h 45m
    0
    10:50 AM
    Pittsburgh
    Grant Street Transportation Center
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $84

Cheapest bus trips Friday

Prices are for one way and one person
  • Greyhound US
    13h 45m
    0
    1:35 AM
    Pittsburgh
    Grant Street Transportation Center
    3:20 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $75
  • Greyhound US
    11h 55m
    0
    6:30 PM
    Pittsburgh
    Grant Street Transportation Center
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $75
  • Greyhound US
    12h 45m
    0
    10:50 AM
    Pittsburgh
    Grant Street Transportation Center
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $91

Cheapest bus trips Saturday

Prices are for one way and one person
  • Greyhound US
    13h 45m
    0
    1:35 AM
    Pittsburgh
    Grant Street Transportation Center
    3:20 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $77
  • Greyhound US
    12h 45m
    0
    10:50 AM
    Pittsburgh
    Grant Street Transportation Center
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $77
  • Greyhound US
    13h 45m
    0
    1:35 AM
    Pittsburgh
    Grant Street Transportation Center
    3:20 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $79
  • Greyhound US
    12h 45m
    0
    10:50 AM
    Pittsburgh
    Grant Street Transportation Center
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $79
  • Greyhound US
    11h 55m
    0
    6:30 PM
    Pittsburgh
    Grant Street Transportation Center
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $84

Frequency of bus connections between Pittsburgh and St. Louis, MO

See here how frequent the connections between Pittsburgh and St. Louis, MO are, during different times and days of the week.
Saturday is the busiest day, with more than 6 daily buses from Pittsburgh to St. Louis, MO. Tuesday has instead the fewest connections, with only 3 daily coaches between Pittsburgh and St. Louis, MO.
The busiest time of the day is the Morning, with 5 buses from Pittsburgh to St. Louis, MO, while Morning sees the fewest connections between Pittsburgh and St. Louis, MO, with 5 offers.

Facts about the bus from Pittsburgh to St. Louis, MO

Compare all providers like Greyhound US that travel 3 times every day by bus from Pittsburgh to St. Louis, MO in one click! Book your bus ticket from Pittsburgh to St. Louis, MO starting from $75!

Cheapest Bus $75
Fastest Bus 11h 55m
Earliest Bus 1:35 AM
Latest Bus 6:30 PM
Daily Bus Routes 3 Ø
Distance 558.2 miles
Bus Companies Greyhound US

Cheapest bus connections from Pittsburgh to St. Louis, MO

Every day, 3 buses from 1 bus companies leave Pittsburgh for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/22/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/22
Monday 06/23
Tuesday 06/24
$75
Wednesday 06/25
Thursday 06/26
$79
Friday 06/27
$75
Saturday 06/28
$77
Sunday 06/29
$79
Monday 06/30
Tuesday 07/01
Wednesday 07/02
Thursday 07/03
$82
Friday 07/04
$78
Saturday 07/05
Sunday 07/06
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
$74
Saturday 07/12
Sunday 07/13
$74
Monday 07/14
Tuesday 07/15
Wednesday 07/16
Thursday 07/17
$77
Friday 07/18
Saturday 07/19

The cheapest time to travel from Pittsburgh to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Pittsburgh to St. Louis, MO, for the next 30 days.
With a price starting from $74, Tuesday is the cheapest day for a bus from Pittsburgh to St. Louis, MO. Thursday instead is the most expensive day with prices starting from $79.
Morning is the cheapest day time for bus tickets from Pittsburgh to St. Louis, MO, with $75. Morning is the most expensive time of the day with prices starting from $75.

How to save money travelling from Pittsburgh to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Pittsburgh to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Pittsburgh to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Pittsburgh to St. Louis, MO are also emptier.

All bus stations and stops in Pittsburgh and St. Louis, MO

In the map below, you can see where to find all bus stations in Pittsburgh and St. Louis, MO.

Service and Comfort on the bus from Pittsburgh to St. Louis, MO

Want to know which seat classes are available on the buses from Pittsburgh to St. Louis, MO? Or which bus companies serve the route Pittsburgh to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Pittsburgh to St. Louis, MO bus

How much does a Pittsburgh St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $75 and takes 13h 45m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Pittsburgh to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $75 and $91. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Pittsburgh to St. Louis, MO each day?

Every day, the Pittsburgh to St. Louis, MO bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Pittsburgh to St. Louis, MO take?

The fastest bus from Pittsburgh to St. Louis, MO is offered by Greyhound US and takes 11h 55m. Bus tickets for this connection cost $75. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Pittsburgh to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Pittsburgh starts at 1:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Pittsburgh to St. Louis, MO?

The latest bus trip departing from Pittsburgh for St. Louis, MO starts at 6:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Pittsburgh St. Louis, MO route?

When traveling by bus from Pittsburgh to St. Louis, MO, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Pittsburgh and St. Louis, MO?

You can check all the direct connections between Pittsburgh and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Pittsburgh to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Pittsburgh St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Pittsburgh St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Pittsburgh to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Pittsburgh to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Pittsburgh and to St. Louis, MO

Here’s an overview of the most popular bus routes to Pittsburgh and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Pittsburgh and to St. Louis, MO
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