Bus from Mobile, AL to St. Louis, MO from $135

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Compare all timetables for the bus from Mobile, AL to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Mobile, AL to St. Louis, MO from various bus operators like Greyhound US for the next days.
today
tomorrow
from $199
Saturday
Sunday
Monday
from $151
Tuesday
from $135
Wednesday

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    18h 35m
    0
    12:15 PM
    Mobile, AL
    Greyhound Bus Station
    6:50 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $199
  • Greyhound US
    21h 55m
    0
    12:05 AM
    Mobile, AL
    Greyhound Bus Station
    10:00 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $200
  • Greyhound US
    32h 10m
    0
    10:55 PM
    Mobile, AL
    Greyhound Bus Station
    7:05 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $200
  • Greyhound US
    23h 50m
    0
    3:55 PM
    Mobile, AL
    Greyhound Bus Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $204
  • Did you know that if you travel from Mobile, AL to St. Louis, MO via Nashville, you can save more than $52? You can find the corresponding connections below.
    • FlixBus
      21h 55m
      0
      12:05 AM
      Mobile, AL
      Greyhound Bus Station
      2:35 PM
      Nashville
      5th Ave South Station
      0
      FlixBus
      Economy
      $101
      • Waiting Time 1h 40m
    • Busbud
      5h 45m
      0
      4:15 PM
      Nashville
      5th Ave South Station
      10:00 PM
      St. Louis, MO
      Gateway Station
      0
      Busbud
      Economy
      $46
    Travel time is 3h 20m longer, but you will save $52

Cheapest bus trips Monday

Prices are for one way and one person
  • Greyhound US
    18h 35m
    0
    12:15 PM
    Mobile, AL
    Greyhound Bus Station
    6:50 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $151
  • Greyhound US
    23h 50m
    0
    3:55 PM
    Mobile, AL
    Greyhound Bus Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $160
  • Greyhound US
    21h 55m
    0
    12:05 AM
    Mobile, AL
    Greyhound Bus Station
    10:00 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $163

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    21h 55m
    0
    12:05 AM
    Mobile, AL
    Greyhound Bus Station
    10:00 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $135
  • Greyhound US
    23h 50m
    0
    3:55 PM
    Mobile, AL
    Greyhound Bus Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $135
  • Greyhound US
    18h 35m
    0
    12:15 PM
    Mobile, AL
    Greyhound Bus Station
    6:50 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $154

Frequency of bus connections between Mobile, AL and St. Louis, MO

See here how frequent the connections between Mobile, AL and St. Louis, MO are, during different times and days of the week.
Friday is the busiest day, with more than 4 daily buses from Mobile, AL to St. Louis, MO. Monday has instead the fewest connections, with only 3 daily coaches between Mobile, AL and St. Louis, MO.
The busiest time of the day is the Afternoon, with 6 buses from Mobile, AL to St. Louis, MO, while Evening sees the fewest connections between Mobile, AL and St. Louis, MO, with 1 offers.

Facts about the bus from Mobile, AL to St. Louis, MO

Compare all providers like Greyhound US that travel 3 times every day by bus from Mobile, AL to St. Louis, MO in one click! Book your bus ticket from Mobile, AL to St. Louis, MO starting from $135!

Cheapest Bus $135
Fastest Bus 18h 35m
Earliest Bus 12:05 AM
Latest Bus 3:55 PM
Daily Bus Routes 3 Ø
Distance 561.1 miles
Bus Companies Greyhound US

Cheapest bus connections from Mobile, AL to St. Louis, MO

Every day, 3 buses from 1 bus companies leave Mobile, AL for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/19/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/15
Monday 06/16
Tuesday 06/17
Wednesday 06/18
Thursday 06/19
Friday 06/20
$199
Saturday 06/21
Sunday 06/22
Monday 06/23
$151
Tuesday 06/24
$135
Wednesday 06/25
Thursday 06/26
Friday 06/27
Saturday 06/28
Sunday 06/29
Monday 06/30
Tuesday 07/01
Wednesday 07/02
Thursday 07/03
Friday 07/04
Saturday 07/05
Sunday 07/06
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
Saturday 07/12

The cheapest time to travel from Mobile, AL to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Mobile, AL to St. Louis, MO, for the next 30 days.
With a price starting from $135, Tuesday is the cheapest day for a bus from Mobile, AL to St. Louis, MO. Friday instead is the most expensive day with prices starting from $199.
Afternoon is the cheapest day time for bus tickets from Mobile, AL to St. Louis, MO, with $135. Evening is the most expensive time of the day with prices starting from $198.

How to save money travelling from Mobile, AL to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mobile, AL to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mobile, AL to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mobile, AL to St. Louis, MO are also emptier.

Beloved bus companies from Mobile, AL to St. Louis, MO

These are the most booked bus companies between Mobile, AL to St. Louis, MO from our users.

Greyhound US from Mobile, AL to St. Louis, MO

Greyhound US

Here you will find the key facts about the Greyhound US bus route Mobile, AL to St. Louis, MO:

Cheapest Price $135
Fastest Bus 18h 35m
Earliest Bus 12:05 AM
Last Bus 3:55 PM
Daily Connections 3 Ø
Found on 6/15/2025

All bus stations and stops in Mobile, AL and St. Louis, MO

In the map below, you can see where to find all bus stations in Mobile, AL and St. Louis, MO.

Service and Comfort on the bus from Mobile, AL to St. Louis, MO

Want to know which seat classes are available on the buses from Mobile, AL to St. Louis, MO? Or which bus companies serve the route Mobile, AL to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Mobile, AL to St. Louis, MO bus

How much does a Mobile, AL St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $135 and takes 23h 50m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Mobile, AL to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $135 and $204. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Mobile, AL to St. Louis, MO each day?

Every day, the Mobile, AL to St. Louis, MO bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mobile, AL to St. Louis, MO take?

The fastest bus from Mobile, AL to St. Louis, MO is offered by Greyhound US and takes 18h 35m. Bus tickets for this connection cost $199. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mobile, AL to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Mobile, AL starts at 12:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mobile, AL to St. Louis, MO?

The latest bus trip departing from Mobile, AL for St. Louis, MO starts at 3:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mobile, AL St. Louis, MO route?

When traveling by bus from Mobile, AL to St. Louis, MO, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mobile, AL and St. Louis, MO?

You can check all the direct connections between Mobile, AL and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Mobile, AL to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mobile, AL St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mobile, AL St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mobile, AL to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Mobile, AL to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mobile, AL and to St. Louis, MO

Here’s an overview of the most popular bus routes to Mobile, AL and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Mobile, AL and to St. Louis, MO
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