Bus from Chicago to St. Louis, MO from $30

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Compare all timetables for the bus from Chicago to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Chicago to St. Louis, MO from various bus operators like Greyhound US or FlixBus for the next days.

today
from $44
tomorrow
from $35
Sunday
Monday
from $41
Tuesday
from $42
Wednesday
from $44
Thursday
from $30

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    6h 0m
    0
    9:45 AM
    Chicago
    Downtown Bus Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $44
  • FlixBus
    6h 35m
    0
    4:30 PM
    Chicago
    Downtown Bus Station
    11:05 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $44
  • FlixBus
    5h 35m
    0
    10:10 AM
    Chicago
    95th Red Line Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $45
  • Greyhound US
    7h 55m
    0
    10:30 PM
    Chicago
    95th Red Line Station
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $92
  • Greyhound US
    9h 10m
    0
    6:10 AM
    Chicago
    Downtown Bus Station
    3:20 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $96

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    5h 35m
    0
    10:10 AM
    Chicago
    95th Red Line Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $35
  • FlixBus
    6h 10m
    0
    12:30 PM
    Chicago
    95th Red Line Station
    6:40 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $35
  • FlixBus
    6h 0m
    0
    9:45 AM
    Chicago
    Downtown Bus Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $42
  • Greyhound US
    9h 25m
    0
    2:10 PM
    Chicago
    95th Red Line Station
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $49
  • Greyhound US
    7h 55m
    0
    10:30 PM
    Chicago
    95th Red Line Station
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $58

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    6h 0m
    0
    9:45 AM
    Chicago
    Downtown Bus Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $41
  • FlixBus
    6h 35m
    0
    4:30 PM
    Chicago
    Downtown Bus Station
    11:05 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $42
  • FlixBus
    6h 0m
    0
    9:45 AM
    Chicago
    Downtown Bus Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $44
  • Greyhound US
    7h 55m
    0
    10:30 PM
    Chicago
    95th Red Line Station
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $72
  • Greyhound US
    7h 55m
    0
    10:30 PM
    Chicago
    95th Red Line Station
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $76

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    6h 0m
    0
    9:45 AM
    Chicago
    Downtown Bus Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $42
  • FlixBus
    6h 40m
    0
    12:00 PM
    Chicago
    Downtown Bus Station
    6:40 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $42
  • FlixBus
    5h 35m
    0
    10:10 AM
    Chicago
    95th Red Line Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $44
  • Greyhound US
    9h 25m
    0
    2:10 PM
    Chicago
    95th Red Line Station
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $51
  • Greyhound US
    8h 50m
    0
    2:45 PM
    Chicago
    Downtown Bus Station
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $58

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    6h 0m
    0
    9:45 AM
    Chicago
    Downtown Bus Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $44
  • FlixBus
    6h 40m
    0
    12:00 PM
    Chicago
    Downtown Bus Station
    6:40 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $44
  • FlixBus
    5h 35m
    0
    10:10 AM
    Chicago
    95th Red Line Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $46
  • Greyhound US
    9h 25m
    0
    2:10 PM
    Chicago
    95th Red Line Station
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $51
  • Greyhound US
    8h 50m
    0
    2:45 PM
    Chicago
    Downtown Bus Station
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $62

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    6h 35m
    0
    4:30 PM
    Chicago
    Downtown Bus Station
    11:05 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $30
  • FlixBus
    6h 10m
    0
    12:15 AM
    Chicago
    Downtown Bus Station
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $48
  • FlixBus
    6h 0m
    0
    9:45 AM
    Chicago
    Downtown Bus Station
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $48
  • Greyhound US
    8h 40m
    0
    9:45 PM
    Chicago
    Downtown Bus Station
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $84
  • Greyhound US
    8h 25m
    0
    10:00 PM
    Chicago
    Union Station
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $84

Frequency of bus connections between Chicago and St. Louis, MO

See here how frequent the connections between Chicago and St. Louis, MO are, during different times and days of the week.
Monday is the busiest day, with more than 16 daily buses from Chicago to St. Louis, MO. Thursday has instead the fewest connections, with only 6 daily coaches between Chicago and St. Louis, MO.
The busiest time of the day is the Morning, with 29 buses from Chicago to St. Louis, MO, while Night sees the fewest connections between Chicago and St. Louis, MO, with 1 offers.

Facts about the bus from Chicago to St. Louis, MO

Compare all providers like Greyhound US and FlixBus that travel 14 times every day by bus from Chicago to St. Louis, MO in one click! Book your bus ticket from Chicago to St. Louis, MO starting from $30!

Cheapest Bus $30
Fastest Bus 5h 35m
Earliest Bus 6:10 AM
Latest Bus 10:00 PM
Daily Bus Routes 14 Ø
Distance 262.3 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from Chicago to St. Louis, MO

Every day, 14 buses from 2 bus companies leave Chicago for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/27/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/22
Monday 06/23
Tuesday 06/24
Wednesday 06/25
Thursday 06/26
Friday 06/27
$44
Saturday 06/28
$35
Sunday 06/29
$133
Monday 06/30
$41
Tuesday 07/01
$42
Wednesday 07/02
$133
Thursday 07/03
$30
Friday 07/04
$40
Saturday 07/05
$132
Sunday 07/06
$44
Monday 07/07
$38
Tuesday 07/08
$34
Wednesday 07/09
$32
Thursday 07/10
$34
Friday 07/11
$34
Saturday 07/12
$36
Sunday 07/13
$40
Monday 07/14
$32
Tuesday 07/15
Wednesday 07/16
$36
Thursday 07/17
Friday 07/18
$37
Saturday 07/19

The cheapest time to travel from Chicago to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to St. Louis, MO, for the next 30 days.
With a price starting from $30, Thursday is the cheapest day for a bus from Chicago to St. Louis, MO. Wednesday instead is the most expensive day with prices starting from $44.
Afternoon is the cheapest day time for bus tickets from Chicago to St. Louis, MO, with $30. Evening is the most expensive time of the day with prices starting from $58.

How to save money travelling from Chicago to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to St. Louis, MO are also emptier.

Beloved bus companies from Chicago to St. Louis, MO

These are the most booked bus companies between Chicago to St. Louis, MO from our users.

FlixBus from Chicago to St. Louis, MO

FlixBus

Here you will find the key facts about the FlixBus bus route Chicago to St. Louis, MO:

Cheapest Price $30
Fastest Bus 5h 35m
Earliest Bus 9:45 AM
Last Bus 4:30 PM
Daily Connections 6 Ø
Found on 6/25/2025

All bus stations and stops in Chicago and St. Louis, MO

In the map below, you can see where to find all bus stations in Chicago and St. Louis, MO.

Service and Comfort on the bus from Chicago to St. Louis, MO

Want to know which seat classes are available on the buses from Chicago to St. Louis, MO? Or which bus companies serve the route Chicago to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Chicago to St. Louis, MO bus

How much does a Chicago St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $30 and takes 6h 35m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Chicago to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $30 and $115. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Chicago to St. Louis, MO each day?

Every day, the Chicago to St. Louis, MO bus route is served by approximately 14 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to St. Louis, MO take?

The fastest bus from Chicago to St. Louis, MO is offered by FlixBus and takes 5h 35m. Bus tickets for this connection cost $51. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Chicago starts at 6:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to St. Louis, MO?

The latest bus trip departing from Chicago for St. Louis, MO starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago St. Louis, MO route?

When traveling by bus from Chicago to St. Louis, MO, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and St. Louis, MO?

You can check all the direct connections between Chicago and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Chicago to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to St. Louis, MO

Here’s an overview of the most popular bus routes to Chicago and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
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