Bus Tampa to St. Louis, MO: Compare prices and save money

Compare all timetables for the bus from Tampa to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Tampa to St. Louis, MO from various bus operators like FlixBus or Greyhound US for the next days.

today

$138

tomorrow

Sunday

Monday

$137

Tuesday

Wednesday

$136

Thursday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	29h 35m	11:10 AM	Tampa	Marion Street	3:45 PM	St. Louis, MO	Gateway Station	Economy	$138	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/19/2025 11:10:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/20/2025 3:45:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 29h 35m
FlixBus	35h 35m	10:35 PM	Tampa	Marion Street	9:10 AM	St. Louis, MO	Gateway Station	Economy	$138	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/19/2025 10:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/21/2025 9:10:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 35h 35m
FlixBus	36h 20m	9:50 PM	Tampa	USF	9:10 AM	St. Louis, MO	Gateway Station	Economy	$138	A Bus from FlixBus goes from USF, Tampa (USA) at 12/19/2025 9:50:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/21/2025 9:10:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 36h 20m
FlixBus	35h 25m	8:00 PM	Tampa	Marion Street	6:25 AM	St. Louis, MO	Gateway Station	Economy	$139	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/19/2025 8:00:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/21/2025 6:25:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 35h 25m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 40m	9:30 AM	Tampa	Marion Street	9:10 AM	St. Louis, MO	Gateway Station	Economy	$137	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/22/2025 9:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/23/2025 9:10:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 24h 40m
FlixBus	35h 35m	10:35 PM	Tampa	Marion Street	9:10 AM	St. Louis, MO	Gateway Station	Economy	$137	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/22/2025 10:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/24/2025 9:10:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 35h 35m
FlixBus	23h 0m	5:55 PM	Tampa	USF	3:55 PM	St. Louis, MO	Gateway Station	Economy	$137	A Bus from FlixBus goes from USF, Tampa (USA) at 12/22/2025 5:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/23/2025 3:55:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 23h 0m
Greyhound US	29h 35m	11:10 AM	Tampa	Marion Street	3:45 PM	St. Louis, MO	Gateway Station	Economy	$138	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/22/2025 11:10:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/23/2025 3:45:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 29h 35m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 40m	9:30 AM	Tampa	Marion Street	9:10 AM	St. Louis, MO	Gateway Station	Economy	$136	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/24/2025 9:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/25/2025 9:10:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 24h 40m
FlixBus	35h 35m	10:35 PM	Tampa	Marion Street	9:10 AM	St. Louis, MO	Gateway Station	Economy	$136	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/24/2025 10:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/26/2025 9:10:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 35h 35m
FlixBus	23h 0m	5:55 PM	Tampa	USF	3:55 PM	St. Louis, MO	Gateway Station	Economy	$136	A Bus from FlixBus goes from USF, Tampa (USA) at 12/24/2025 5:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/25/2025 3:55:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 23h 0m
Greyhound US	29h 35m	11:10 AM	Tampa	Marion Street	3:45 PM	St. Louis, MO	Gateway Station	Economy	$137	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/24/2025 11:10:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/25/2025 3:45:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 29h 35m

Best Price Offer: The price for the cheapest bus from Tampa to St. Louis, MO is $115 on 12/15/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Tampa and St. Louis, MO

See here how frequent the connections between Tampa and St. Louis, MO are, during different times and days of the week.

Monday is the busiest day, with more than 12 daily buses from Tampa to St. Louis, MO. Friday has instead the fewest connections, with only 11 daily coaches between Tampa and St. Louis, MO.

The busiest time of the day is the Evening, with 13 buses from Tampa to St. Louis, MO, while Morning sees the fewest connections between Tampa and St. Louis, MO, with 10 offers.

Facts about the bus from Tampa to St. Louis, MO

Compare all providers like FlixBus and Greyhound US that travel 11 times every day by bus from Tampa to St. Louis, MO in one click! Book your bus ticket from Tampa to St. Louis, MO starting from $115!

Cheapest Bus	$115
Fastest Bus	22h 0m
Earliest Bus	11:10 AM
Latest Bus	10:35 PM
Daily Bus Routes	11 Ø
Distance	861.7 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Tampa to St. Louis, MO

Every day, 11 buses from 2 bus companies leave Tampa for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/19/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

$140

Saturday 12/20

Sunday 12/21

Monday 12/22

$138

Tuesday 12/23

Wednesday 12/24

$136

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

$140

Wednesday 12/31

$131

Thursday 01/01

Friday 01/02

$158

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

$128

Friday 01/09

$124

Saturday 01/10

The cheapest time to travel from Tampa to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Tampa to St. Louis, MO, for the next 30 days.

With a price starting from $120, Monday is the cheapest day for a bus from Tampa to St. Louis, MO. Wednesday instead is the most expensive day with prices starting from $131.

Afternoon is the cheapest day time for bus tickets from Tampa to St. Louis, MO, with $136. Morning is the most expensive time of the day with prices starting from $136.

How to save money travelling from Tampa to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tampa to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tampa to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tampa to St. Louis, MO are also emptier.

All bus stations and stops in Tampa and St. Louis, MO

In the map below, you can see where to find all bus stations in Tampa and St. Louis, MO.

Marion Street

N Marion St 1211

USF

USF Holly Drive 3755

Greyhound Bus Station

East Polk Street 602

Western Union

Tampa Gateway Blvd, I 4 Exit 10 11706

Port of Tampa Cruise Terminals

Channelside Dr. 1101

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Service and Comfort on the bus from Tampa to St. Louis, MO

Want to know which seat classes are available on the buses from Tampa to St. Louis, MO? Or which bus companies serve the route Tampa to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Tampa to St. Louis, MO bus

How much does a Tampa St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $115 and takes 34h 35m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Tampa to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $115 and $178. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Tampa to St. Louis, MO each day?

Every day, the Tampa to St. Louis, MO bus route is served by approximately 11 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tampa to St. Louis, MO take?

The fastest bus from Tampa to St. Louis, MO is offered by FlixBus and takes 22h 0m. Bus tickets for this connection cost $154. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tampa to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Tampa starts at 11:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tampa to St. Louis, MO?

The latest bus trip departing from Tampa for St. Louis, MO starts at 10:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tampa St. Louis, MO route?

When traveling by bus from Tampa to St. Louis, MO, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tampa and St. Louis, MO?

You can check all the direct connections between Tampa and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Tampa to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tampa St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tampa St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tampa to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Tampa to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 11 daily trips between Tampa and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Tampa to St. Louis, MO?

Prices and availability for 11 trips between Tampa and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Tampa to St. Louis, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tampa and to St. Louis, MO

Here’s an overview of the most popular bus routes to Tampa and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!