Bus Detroit to St. Louis, MO: Compare prices and save money

Compare all timetables for the bus from Detroit to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Detroit to St. Louis, MO from various bus operators like Greyhound US for the next days.

today

from $100

tomorrow

Sunday

from $100

Monday

from $102

Tuesday

from $74

Wednesday

from $74

Thursday

from $92

Cheapest bus trips today

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 30m	8:35 AM	Detroit	Central Bus Station	11:05 PM	St. Louis, MO	Gateway Station	Economy	$100	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/18/2025 8:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/18/2025 11:05:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 14h 30m
Greyhound US	15h 55m	11:25 PM	Detroit	Central Bus Station	3:20 PM	St. Louis, MO	Gateway Station	Economy	$102	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/18/2025 11:25:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/19/2025 3:20:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 15h 55m
Greyhound US	14h 5m	4:20 PM	Detroit	Central Bus Station	6:25 AM	St. Louis, MO	Gateway Station	Economy	$105	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/18/2025 4:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/19/2025 6:25:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 14h 5m

Did you know that if you travel from Detroit to St. Louis, MO via Chicago, you can save more than $33? You can find the corresponding connections below.
- FlixBus
  
  14h 30m
  
  0
  
  8:35 AM
  
  Detroit
  Central Bus Station
  
  2:20 PM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $41
  
  A Bus from FlixBus goes from Central Bus Station, Detroit (USA) at 7/20/2025 8:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 7/20/2025 2:20:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 5h 45m
- Busbud
  
  6h 35m
  
  0
  
  4:30 PM
  
  Chicago
  Downtown Bus Station
  
  11:05 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $26
  
  A Bus from Busbud goes from Downtown Bus Station, Chicago (USA) at 7/20/2025 4:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/20/2025 11:05:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 6h 35m
Travel time is 0h 25m longer, but you will save $33

Cheapest bus trips Sunday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 30m	8:35 AM	Detroit	Central Bus Station	11:05 PM	St. Louis, MO	Gateway Station	Economy	$100	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/20/2025 8:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/20/2025 11:05:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 14h 30m
Greyhound US	15h 55m	11:25 PM	Detroit	Central Bus Station	3:20 PM	St. Louis, MO	Gateway Station	Economy	$101	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/20/2025 11:25:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/21/2025 3:20:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 15h 55m
Greyhound US	14h 5m	4:20 PM	Detroit	Central Bus Station	6:25 AM	St. Louis, MO	Gateway Station	Economy	$105	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/20/2025 4:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/21/2025 6:25:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 14h 5m

Did you know that if you travel from Detroit to St. Louis, MO via Chicago, you can save more than $33? You can find the corresponding connections below.
- FlixBus
  
  14h 30m
  
  0
  
  8:35 AM
  
  Detroit
  Central Bus Station
  
  2:20 PM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $41
  
  A Bus from FlixBus goes from Central Bus Station, Detroit (USA) at 7/20/2025 8:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 7/20/2025 2:20:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 5h 45m
- Busbud
  
  6h 35m
  
  0
  
  4:30 PM
  
  Chicago
  Downtown Bus Station
  
  11:05 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $26
  
  A Bus from Busbud goes from Downtown Bus Station, Chicago (USA) at 7/20/2025 4:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/20/2025 11:05:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 6h 35m
Travel time is 0h 25m longer, but you will save $33

Cheapest bus trips Monday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 5m	4:20 PM	Detroit	Central Bus Station	6:25 AM	St. Louis, MO	Gateway Station	Economy	$102	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/21/2025 4:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/22/2025 6:25:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 14h 5m
Greyhound US	14h 30m	8:35 AM	Detroit	Central Bus Station	11:05 PM	St. Louis, MO	Gateway Station	Economy	$103	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/21/2025 8:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/21/2025 11:05:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 14h 30m
Greyhound US	14h 5m	4:20 PM	Detroit	Central Bus Station	6:25 AM	St. Louis, MO	Gateway Station	Economy	$104	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/21/2025 4:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/22/2025 6:25:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 14h 5m
Greyhound US	14h 30m	8:35 AM	Detroit	Central Bus Station	11:05 PM	St. Louis, MO	Gateway Station	Economy	$105	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/21/2025 8:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/21/2025 11:05:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 14h 30m
Greyhound US	15h 55m	11:25 PM	Detroit	Central Bus Station	3:20 PM	St. Louis, MO	Gateway Station	Economy	$114	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/21/2025 11:25:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/22/2025 3:20:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 15h 55m

Did you know that if you travel from Detroit to St. Louis, MO via Chicago, you can save more than $42? You can find the corresponding connections below.
- Busbud
  
  14h 30m
  
  0
  
  8:35 AM
  
  Detroit
  Central Bus Station
  
  2:20 PM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $34
  
  A Bus from Busbud goes from Central Bus Station, Detroit (USA) at 7/23/2025 8:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 7/23/2025 2:20:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 5h 45m
- Busbud
  
  6h 35m
  
  0
  
  4:30 PM
  
  Chicago
  Downtown Bus Station
  
  11:05 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $26
  
  A Bus from Busbud goes from Downtown Bus Station, Chicago (USA) at 7/23/2025 4:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/23/2025 11:05:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 6h 35m
Travel time is 0h 25m longer, but you will save $42

Cheapest bus trips Tuesday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 5m	4:20 PM	Detroit	Central Bus Station	6:25 AM	St. Louis, MO	Gateway Station	Economy	$74	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/22/2025 4:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/23/2025 6:25:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 14h 5m
Greyhound US	14h 30m	8:35 AM	Detroit	Central Bus Station	11:05 PM	St. Louis, MO	Gateway Station	Economy	$75	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/22/2025 8:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/22/2025 11:05:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 14h 30m
Greyhound US	14h 5m	4:20 PM	Detroit	Central Bus Station	6:25 AM	St. Louis, MO	Gateway Station	Economy	$78	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/22/2025 4:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/23/2025 6:25:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 14h 5m
Greyhound US	14h 30m	8:35 AM	Detroit	Central Bus Station	11:05 PM	St. Louis, MO	Gateway Station	Economy	$79	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/22/2025 8:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/22/2025 11:05:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 14h 30m
Greyhound US	15h 55m	11:25 PM	Detroit	Central Bus Station	3:20 PM	St. Louis, MO	Gateway Station	Economy	$86	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/22/2025 11:25:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/23/2025 3:20:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 15h 55m

Did you know that if you travel from Detroit to St. Louis, MO via Chicago, you can save more than $14? You can find the corresponding connections below.
- Busbud
  
  14h 30m
  
  0
  
  8:35 AM
  
  Detroit
  Central Bus Station
  
  2:20 PM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $34
  
  A Bus from Busbud goes from Central Bus Station, Detroit (USA) at 7/23/2025 8:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 7/23/2025 2:20:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 5h 45m
- Busbud
  
  6h 35m
  
  0
  
  4:30 PM
  
  Chicago
  Downtown Bus Station
  
  11:05 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $26
  
  A Bus from Busbud goes from Downtown Bus Station, Chicago (USA) at 7/23/2025 4:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/23/2025 11:05:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 6h 35m
Travel time is 0h 25m longer, but you will save $14

Cheapest bus trips Wednesday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 55m	11:25 PM	Detroit	Central Bus Station	3:20 PM	St. Louis, MO	Gateway Station	Economy	$74	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/23/2025 11:25:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/24/2025 3:20:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 15h 55m
Greyhound US	14h 30m	8:35 AM	Detroit	Central Bus Station	11:05 PM	St. Louis, MO	Gateway Station	Economy	$75	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/23/2025 8:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/23/2025 11:05:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 14h 30m
Greyhound US	14h 5m	4:20 PM	Detroit	Central Bus Station	6:25 AM	St. Louis, MO	Gateway Station	Economy	$75	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/23/2025 4:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/24/2025 6:25:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 14h 5m
Greyhound US	15h 55m	11:25 PM	Detroit	Central Bus Station	3:20 PM	St. Louis, MO	Gateway Station	Economy	$78	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/23/2025 11:25:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/24/2025 3:20:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 15h 55m
Greyhound US	14h 30m	8:35 AM	Detroit	Central Bus Station	11:05 PM	St. Louis, MO	Gateway Station	Economy	$79	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/23/2025 8:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/23/2025 11:05:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 14h 30m

Did you know that if you travel from Detroit to St. Louis, MO via Chicago, you can save more than $14? You can find the corresponding connections below.
- Busbud
  
  14h 30m
  
  0
  
  8:35 AM
  
  Detroit
  Central Bus Station
  
  2:20 PM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $34
  
  A Bus from Busbud goes from Central Bus Station, Detroit (USA) at 7/23/2025 8:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 7/23/2025 2:20:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 5h 45m
- Busbud
  
  6h 35m
  
  0
  
  4:30 PM
  
  Chicago
  Downtown Bus Station
  
  11:05 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $26
  
  A Bus from Busbud goes from Downtown Bus Station, Chicago (USA) at 7/23/2025 4:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/23/2025 11:05:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 6h 35m
Travel time is 0h 25m longer, but you will save $14

Cheapest bus trips Thursday

Prices are for one way and one person
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 55m	11:25 PM	Detroit	Central Bus Station	3:20 PM	St. Louis, MO	Gateway Station	Economy	$92	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/24/2025 11:25:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/25/2025 3:20:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 15h 55m
Greyhound US	14h 30m	8:35 AM	Detroit	Central Bus Station	11:05 PM	St. Louis, MO	Gateway Station	Economy	$98	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/24/2025 8:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 7/24/2025 11:05:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 14h 30m
Greyhound US	14h 5m	4:20 PM	Detroit	Central Bus Station	6:25 AM	St. Louis, MO	Gateway Station	Economy	$99	A Bus from Greyhound US goes from Central Bus Station, Detroit (USA) at 7/24/2025 4:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/25/2025 6:25:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 14h 5m

Did you know that if you travel from Detroit to St. Louis, MO via Chicago, you can save more than $32? You can find the corresponding connections below.
- Busbud
  
  14h 30m
  
  0
  
  8:35 AM
  
  Detroit
  Central Bus Station
  
  2:20 PM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $34
  
  A Bus from Busbud goes from Central Bus Station, Detroit (USA) at 7/23/2025 8:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 7/23/2025 2:20:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 5h 45m
- Busbud
  
  6h 35m
  
  0
  
  4:30 PM
  
  Chicago
  Downtown Bus Station
  
  11:05 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $26
  
  A Bus from Busbud goes from Downtown Bus Station, Chicago (USA) at 7/23/2025 4:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 7/23/2025 11:05:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 6h 35m
Travel time is 0h 25m longer, but you will save $32

Frequency of bus connections between Detroit and St. Louis, MO

See here how frequent the connections between Detroit and St. Louis, MO are, during different times and days of the week.

Monday is the busiest day, with more than 6 daily buses from Detroit to St. Louis, MO. Sunday has instead the fewest connections, with only 3 daily coaches between Detroit and St. Louis, MO.

The busiest time of the day is the Morning, with 9 buses from Detroit to St. Louis, MO, while Morning sees the fewest connections between Detroit and St. Louis, MO, with 9 offers.

Facts about the bus from Detroit to St. Louis, MO

Compare all providers like Greyhound US that travel 4 times every day by bus from Detroit to St. Louis, MO in one click! Book your bus ticket from Detroit to St. Louis, MO starting from $74!

Cheapest Bus	$74
Fastest Bus	14h 5m
Earliest Bus	8:35 AM
Latest Bus	11:25 PM
Daily Bus Routes	4 Ø
Distance	454.7 miles
Bus Companies	Greyhound US

Cheapest bus connections from Detroit to St. Louis, MO

Every day, 4 buses from 1 bus companies leave Detroit for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/18/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/13

Monday 07/14

Tuesday 07/15

Wednesday 07/16

Thursday 07/17

Friday 07/18

$100

Saturday 07/19

Sunday 07/20

$100

Monday 07/21

$102

Tuesday 07/22

$74

Wednesday 07/23

$74

Thursday 07/24

$92

Friday 07/25

$85

Saturday 07/26

Sunday 07/27

Monday 07/28

Tuesday 07/29

Wednesday 07/30

Thursday 07/31

$78

Friday 08/01

$88

Saturday 08/02

Sunday 08/03

$71

Monday 08/04

Tuesday 08/05

$77

Wednesday 08/06

Thursday 08/07

$77

Friday 08/08

$74

Saturday 08/09

The cheapest time to travel from Detroit to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Detroit to St. Louis, MO, for the next 30 days.

With a price starting from $74, Tuesday is the cheapest day for a bus from Detroit to St. Louis, MO. Monday instead is the most expensive day with prices starting from $102.

Afternoon is the cheapest day time for bus tickets from Detroit to St. Louis, MO, with $74. Morning is the most expensive time of the day with prices starting from $75.

How to save money travelling from Detroit to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Detroit to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Detroit to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Detroit to St. Louis, MO are also emptier.

Beloved bus companies from Detroit to St. Louis, MO

These are the most booked bus companies between Detroit to St. Louis, MO from our users.

Greyhound US from Detroit to St. Louis, MO

Here you will find the key facts about the Greyhound US bus route Detroit to St. Louis, MO:

Cheapest Price	$74
Fastest Bus	14h 5m
Earliest Bus	8:35 AM
Last Bus	11:25 PM
Daily Connections	4 Ø
Found on	7/16/2025

All bus stations and stops in Detroit and St. Louis, MO

In the map below, you can see where to find all bus stations in Detroit and St. Louis, MO.

Central Bus Station

Howard St 1001

Amtrak

W Baltimore Ave 78

VA Medical Center Blue Deck

East Canfield Street (between John R. and Brush St.) 225

Park Avenue

Rosa Parks TC

Cass Ave 1310

Gateway Station

S 15th St 430

Lindbergh @ Hackberry NB Bus Stop

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Service and Comfort on the bus from Detroit to St. Louis, MO

Want to know which seat classes are available on the buses from Detroit to St. Louis, MO? Or which bus companies serve the route Detroit to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Detroit to St. Louis, MO bus

How much does a Detroit St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $74 and takes 14h 5m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Detroit to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $74 and $118. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Detroit to St. Louis, MO each day?

Every day, the Detroit to St. Louis, MO bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Detroit to St. Louis, MO take?

The fastest bus from Detroit to St. Louis, MO is offered by Greyhound US and takes 14h 5m. Bus tickets for this connection cost $105. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Detroit to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Detroit starts at 8:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Detroit to St. Louis, MO?

The latest bus trip departing from Detroit for St. Louis, MO starts at 11:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Detroit St. Louis, MO route?

When traveling by bus from Detroit to St. Louis, MO, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Detroit and St. Louis, MO?

You can check all the direct connections between Detroit and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Detroit to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Detroit St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Detroit St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Detroit to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Detroit to St. Louis, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Detroit and to St. Louis, MO

Here’s an overview of the most popular bus routes to Detroit and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!