Bus Greenville, SC to Detroit: Compare prices and save money

Compare all timetables for the bus from Greenville, SC to Detroit

Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to Detroit from various bus operators like FlixBus or Greyhound US for the next days.

today

$125

tomorrow

$153

Saturday

Sunday

$143

Monday

Tuesday

$136

Wednesday

$140

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	19h 45m	10:00 PM	Greenville, SC	Woodruff Rd	5:45 PM	Detroit	Central Bus Station		Economy	$125	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 12/18/2025 10:00:00 PM to Central Bus Station, Detroit (USA) arriving at 12/19/2025 5:45:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 19h 45m
	Greyhound US	19h 10m	2:45 PM	Greenville, SC	Woodruff Rd	9:55 AM	Detroit	Central Bus Station		Economy	$128	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 12/18/2025 2:45:00 PM to Central Bus Station, Detroit (USA) arriving at 12/19/2025 9:55:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 19h 10m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	19h 45m	10:00 PM	Greenville, SC	Woodruff Rd	5:45 PM	Detroit	Central Bus Station		Economy	$153	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 12/19/2025 10:00:00 PM to Central Bus Station, Detroit (USA) arriving at 12/20/2025 5:45:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 19h 45m
	Greyhound US	19h 10m	2:45 PM	Greenville, SC	Woodruff Rd	9:55 AM	Detroit	Central Bus Station		Economy	$166	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 12/19/2025 2:45:00 PM to Central Bus Station, Detroit (USA) arriving at 12/20/2025 9:55:00 AM. 50 Economy ticket for $166 per person are available. Travel duration is 19h 10m

Did you know that if you travel from Windsor, ON to Greenville, SC via Detroit, you can save more than $138? You will find the corresponding connections below.
- Save more than 90%
  
  0h 40m
  
  0 mi
  
  8:35 PM
  
  Windsor, ON
  International Transit Terminal
  
  9:15 PM
  
  Detroit
  Central Bus Station
  
  517 mi
  
  Greenville, SC
  
  Economy
  
  $15
  
  A Bus from goes from International Transit Terminal, Windsor, ON (Canada) at 12/19/2025 8:35:00 PM to Central Bus Station, Detroit (USA) arriving at 12/19/2025 9:15:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 0h 40m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	19h 10m	2:45 PM	Greenville, SC	Woodruff Rd	9:55 AM	Detroit	Central Bus Station		Economy	$143	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 12/21/2025 2:45:00 PM to Central Bus Station, Detroit (USA) arriving at 12/22/2025 9:55:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 19h 10m
	FlixBus	19h 45m	10:00 PM	Greenville, SC	Woodruff Rd	5:45 PM	Detroit	Central Bus Station		Economy	$143	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 12/21/2025 10:00:00 PM to Central Bus Station, Detroit (USA) arriving at 12/22/2025 5:45:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 19h 45m

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	19h 45m	10:00 PM	Greenville, SC	Woodruff Rd	5:45 PM	Detroit	Central Bus Station		Economy	$136	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 12/23/2025 10:00:00 PM to Central Bus Station, Detroit (USA) arriving at 12/24/2025 5:45:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 19h 45m
	Greyhound US	19h 10m	2:45 PM	Greenville, SC	Woodruff Rd	9:55 AM	Detroit	Central Bus Station		Economy	$160	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 12/23/2025 2:45:00 PM to Central Bus Station, Detroit (USA) arriving at 12/24/2025 9:55:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 19h 10m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	19h 45m	10:00 PM	Greenville, SC	Woodruff Rd	5:45 PM	Detroit	Central Bus Station		Economy	$140	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 12/24/2025 10:00:00 PM to Central Bus Station, Detroit (USA) arriving at 12/25/2025 5:45:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 19h 45m
	Greyhound US	19h 10m	2:45 PM	Greenville, SC	Woodruff Rd	9:55 AM	Detroit	Central Bus Station		Economy	$141	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 12/24/2025 2:45:00 PM to Central Bus Station, Detroit (USA) arriving at 12/25/2025 9:55:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 19h 10m

Did you know that if you travel from Windsor, ON to Greenville, SC via Detroit, you can save more than $127? You will find the corresponding connections below.
- FlixBus
  
  Save more than 91%
  
  0h 40m
  
  0 mi
  
  8:35 PM
  
  Windsor, ON
  International Transit Terminal
  
  9:15 PM
  
  Detroit
  Central Bus Station
  
  517 mi
  
  Greenville, SC
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from International Transit Terminal, Windsor, ON (Canada) at 12/24/2025 8:35:00 PM to Central Bus Station, Detroit (USA) arriving at 12/24/2025 9:15:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 0h 40m

Best Price Offer: The price for the cheapest bus from Greenville, SC to Detroit is $116 on 12/25/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Greenville, SC and Detroit

See here how frequent the connections between Greenville, SC and Detroit are, during different times and days of the week.

Sunday is the busiest day, with more than 4 daily buses from Greenville, SC to Detroit. Tuesday has instead the fewest connections, with only 2 daily coaches between Greenville, SC and Detroit.

The busiest time of the day is the Afternoon, with 6 buses from Greenville, SC to Detroit, while Afternoon sees the fewest connections between Greenville, SC and Detroit, with 6 offers.

Facts about the bus from Greenville, SC to Detroit

Compare all providers like FlixBus and Greyhound US that travel 2 times every day by bus from Greenville, SC to Detroit in one click! Book your bus ticket from Greenville, SC to Detroit starting from $116!

Cheapest Bus	$116
Fastest Bus	19h 10m
Earliest Bus	2:45 PM
Latest Bus	10:00 PM
Daily Bus Routes	2 Ø
Distance	518.2 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Greenville, SC to Detroit

Every day, 2 buses from 2 bus companies leave Greenville, SC for Detroit: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/18/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

$125

Friday 12/19

$153

Saturday 12/20

Sunday 12/21

$159

Monday 12/22

Tuesday 12/23

$136

Wednesday 12/24

$140

Thursday 12/25

$116

Friday 12/26

$128

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

$128

Friday 01/02

Saturday 01/03

Sunday 01/04

$130

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Greenville, SC to Detroit

See here on which day and which time of the day you can find the cheapest bus ticket from Greenville, SC to Detroit, for the next 30 days.

With a price starting from $114, Sunday is the cheapest day for a bus from Greenville, SC to Detroit. Wednesday instead is the most expensive day with prices starting from $140.

Evening is the cheapest day time for bus tickets from Greenville, SC to Detroit, with $125. Afternoon is the most expensive time of the day with prices starting from $128.

How to save money travelling from Greenville, SC to Detroit

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Greenville, SC to Detroit in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to Detroit, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to Detroit are also emptier.

All bus stations and stops in Greenville, SC and Detroit

In the map below, you can see where to find all bus stations in Greenville, SC and Detroit.

McDonald's

Woodruff Rd 1111

Woodruff Rd

Woodruff Rd 1116

Guadalajara Supermarket

White Horse Rd 2803

Greyhound Bus Station

Hendrix Dr 9

N Church St

Central Bus Station

Howard St 1001

Amtrak

W Baltimore Ave 78

VA Medical Center Blue Deck

East Canfield Street (between John R. and Brush St.) 225

Park Avenue

Rosa Parks TC

Cass Ave 1310

Service and Comfort on the bus from Greenville, SC to Detroit

Want to know which seat classes are available on the buses from Greenville, SC to Detroit? Or which bus companies serve the route Greenville, SC to Detroit? Below you will find answers to your questions.

FAQs about the Greenville, SC to Detroit bus

How much does a Greenville, SC Detroit bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $116 and takes 19h 45m to reach Detroit. Compare offers to save money!

How much could I save by comparing buses from Greenville, SC to Detroit?

This route is offered by 2 companies with a range of ticket prices between $116 and $166. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Detroit.

On average, how many connections are available from Greenville, SC to Detroit each day?

Every day, the Greenville, SC to Detroit bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Greenville, SC to Detroit take?

The fastest bus from Greenville, SC to Detroit is offered by Greyhound US and takes 19h 10m. Bus tickets for this connection cost $128. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Greenville, SC to Detroit?

The earliest bus arriving in Detroit from Greenville, SC starts at 2:45 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Greenville, SC to Detroit?

The latest bus trip departing from Greenville, SC for Detroit starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Greenville, SC Detroit route?

When traveling by bus from Greenville, SC to Detroit, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Greenville, SC and Detroit?

You can check all the direct connections between Greenville, SC and Detroit by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Greenville, SC to Detroit bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC Detroit bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Greenville, SC Detroit bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to Detroit on your planned travel date.

How does CheckMyBus find the best bus deals from Greenville, SC to Detroit?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Greenville, SC and Detroit. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Greenville, SC to Detroit?

Prices and availability for 2 trips between Greenville, SC and Detroit change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Greenville, SC to Detroit

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Greenville, SC and to Detroit

Here’s an overview of the most popular bus routes to Greenville, SC and to Detroit. Simply click on the connection of your choice, and you will find all the details about your bus route!