Bus from Greenville, SC to Detroit from $101

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Compare all timetables for the bus from Greenville, SC to Detroit

Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to Detroit from various bus operators like FlixBus or Greyhound US for the next days.

today
tomorrow
$149
Sunday
$101
Monday
Tuesday
Wednesday
$128
Thursday
$118

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 19h 10m 2:45 PM Greenville, SC Woodruff Rd 9:55 AM Detroit Central Bus Station  Economy $149
FlixBus 19h 45m 10:00 PM Greenville, SC Woodruff Rd 5:45 PM Detroit Central Bus Station  Economy $149
  • Did you know that if you travel from Windsor, ON to Greenville, SC via Detroit, you can save more than $137? You will find the corresponding connections below.
    • FlixBus
      Save more than 92%
      0h 40m
      0 mi
      8:35 PM
      Windsor, ON
      International Transit Terminal
      9:15 PM
      Detroit
      Central Bus Station
      517 mi
      Greenville, SC
      FlixBus
      Economy
      $12
  • Did you know that if you travel from Greenville, SC to Detroit via Charlotte, you can save more than $50? You can find the corresponding connections below.
    • FlixBus
      19h 45m
      0
      10:00 PM
      Greenville, SC
      Woodruff Rd
      11:50 PM
      Charlotte
      W Trade St
      0
      FlixBus
      Economy
      $21
      • Waiting Time 3h 0m
    • Busbud
      14h 55m
      0
      2:50 AM
      Charlotte
      W Trade St
      5:45 PM
      Detroit
      Central Bus Station
      0
      Busbud
      Economy
      $78
    Travel time is 0h 35m longer, but you will save $50

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 19h 10m 2:45 PM Greenville, SC Woodruff Rd 9:55 AM Detroit Central Bus Station  Economy $101
FlixBus 19h 45m 10:00 PM Greenville, SC Woodruff Rd 5:45 PM Detroit Central Bus Station  Economy $101

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 19h 45m 10:00 PM Greenville, SC Woodruff Rd 5:45 PM Detroit Central Bus Station  Economy $128
Greyhound US 19h 10m 2:45 PM Greenville, SC Woodruff Rd 9:55 AM Detroit Central Bus Station  Economy $129
  • Did you know that if you travel from Greenville, SC to Detroit via Charlotte, you can save more than $29? You can find the corresponding connections below.
    • FlixBus
      19h 45m
      0
      10:00 PM
      Greenville, SC
      Woodruff Rd
      11:50 PM
      Charlotte
      W Trade St
      0
      FlixBus
      Economy
      $21
      • Waiting Time 3h 0m
    • Busbud
      14h 55m
      0
      2:50 AM
      Charlotte
      W Trade St
      5:45 PM
      Detroit
      Central Bus Station
      0
      Busbud
      Economy
      $78
    Travel time is 0h 35m longer, but you will save $29

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 19h 10m 2:45 PM Greenville, SC Woodruff Rd 9:55 AM Detroit Central Bus Station  Economy $118
FlixBus 19h 45m 10:00 PM Greenville, SC Woodruff Rd 5:45 PM Detroit Central Bus Station  Economy $121
  • Did you know that if you travel from Greenville, SC to Detroit via Charlotte, you can save more than $19? You can find the corresponding connections below.
    • FlixBus
      19h 45m
      0
      10:00 PM
      Greenville, SC
      Woodruff Rd
      11:50 PM
      Charlotte
      W Trade St
      0
      FlixBus
      Economy
      $21
      • Waiting Time 3h 0m
    • Busbud
      14h 55m
      0
      2:50 AM
      Charlotte
      W Trade St
      5:45 PM
      Detroit
      Central Bus Station
      0
      Busbud
      Economy
      $78
    Travel time is 0h 35m longer, but you will save $19

Best Price Offer: The price for the cheapest bus from Greenville, SC to Detroit is $101 on 12/7/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Greenville, SC and Detroit

See here how frequent the connections between Greenville, SC and Detroit are, during different times and days of the week.
Sunday is the busiest day, with more than 4 daily buses from Greenville, SC to Detroit. Sunday has instead the fewest connections, with only 4 daily coaches between Greenville, SC and Detroit.
The busiest time of the day is the Afternoon, with 8 buses from Greenville, SC to Detroit, while Afternoon sees the fewest connections between Greenville, SC and Detroit, with 8 offers.

Facts about the bus from Greenville, SC to Detroit

Compare all providers like FlixBus and Greyhound US that travel 4 times every day by bus from Greenville, SC to Detroit in one click! Book your bus ticket from Greenville, SC to Detroit starting from $101!

Cheapest Bus $101
Fastest Bus 19h 10m
Earliest Bus 2:45 PM
Latest Bus 10:00 PM
Daily Bus Routes 4 Ø
Distance 518.2 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Greenville, SC to Detroit

Every day, 4 buses from 2 bus companies leave Greenville, SC for Detroit: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 11/30
Monday 12/01
Tuesday 12/02
Wednesday 12/03
Thursday 12/04
Friday 12/05
Saturday 12/06
$149
Sunday 12/07
$101
Monday 12/08
Tuesday 12/09
Wednesday 12/10
$129
Thursday 12/11
$118
Friday 12/12
$117
Saturday 12/13
$140
Sunday 12/14
Monday 12/15
Tuesday 12/16
Wednesday 12/17
Thursday 12/18
Friday 12/19
Saturday 12/20
Sunday 12/21
$140
Monday 12/22
Tuesday 12/23
Wednesday 12/24
Thursday 12/25
$115
Friday 12/26
Saturday 12/27

The cheapest time to travel from Greenville, SC to Detroit

See here on which day and which time of the day you can find the cheapest bus ticket from Greenville, SC to Detroit, for the next 30 days.
With a price starting from $101, Sunday is the cheapest day for a bus from Greenville, SC to Detroit. Saturday instead is the most expensive day with prices starting from $140.
Evening is the cheapest day time for bus tickets from Greenville, SC to Detroit, with $101. Afternoon is the most expensive time of the day with prices starting from $101.

How to save money travelling from Greenville, SC to Detroit

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Greenville, SC to Detroit in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to Detroit, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to Detroit are also emptier.

All bus stations and stops in Greenville, SC and Detroit

In the map below, you can see where to find all bus stations in Greenville, SC and Detroit.

Service and Comfort on the bus from Greenville, SC to Detroit

Want to know which seat classes are available on the buses from Greenville, SC to Detroit? Or which bus companies serve the route Greenville, SC to Detroit? Below you will find answers to your questions.

FAQs about the Greenville, SC to Detroit bus

How much does a Greenville, SC Detroit bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $101 and takes 19h 45m to reach Detroit. Compare offers to save money!

How much could I save by comparing buses from Greenville, SC to Detroit?

This route is offered by 2 companies with a range of ticket prices between $101 and $150. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Detroit.

On average, how many connections are available from Greenville, SC to Detroit each day?

Every day, the Greenville, SC to Detroit bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Greenville, SC to Detroit take?

The fastest bus from Greenville, SC to Detroit is offered by Greyhound US and takes 19h 10m. Bus tickets for this connection cost $150. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Greenville, SC to Detroit?

The earliest bus arriving in Detroit from Greenville, SC starts at 2:45 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Greenville, SC to Detroit?

The latest bus trip departing from Greenville, SC for Detroit starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Greenville, SC Detroit route?

When traveling by bus from Greenville, SC to Detroit, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Greenville, SC and Detroit?

You can check all the direct connections between Greenville, SC and Detroit by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Greenville, SC to Detroit bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC Detroit bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Greenville, SC Detroit bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to Detroit on your planned travel date.

Available seat classes which are offered on the bus route Greenville, SC to Detroit

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Greenville, SC and to Detroit

Here’s an overview of the most popular bus routes to Greenville, SC and to Detroit. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Greenville, SC and to Detroit
CheckMyBus › Buses in USA › Bus to Greenville, SC › Bus to Detroit

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