Bus Greenville, SC to Detroit: Compare prices and save money

Compare all timetables for the bus from Greenville, SC to Detroit

Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to Detroit from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$87

Thursday

$90

Friday

$96

Saturday

$92

Sunday

$93

Monday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	19h 45m	10:00 PM	Greenville, SC	Woodruff Rd	5:45 PM	Detroit	Central Bus Station		Economy	$87	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/25/2026 10:00:00 PM to Central Bus Station, Detroit (USA) arriving at 3/26/2026 5:45:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 19h 45m
	Greyhound US	19h 10m	2:45 PM	Greenville, SC	Woodruff Rd	9:55 AM	Detroit	Central Bus Station		Economy	$88	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 3/25/2026 2:45:00 PM to Central Bus Station, Detroit (USA) arriving at 3/26/2026 9:55:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 19h 10m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	19h 45m	10:00 PM	Greenville, SC	Woodruff Rd	5:45 PM	Detroit	Central Bus Station		Economy	$90	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/26/2026 10:00:00 PM to Central Bus Station, Detroit (USA) arriving at 3/27/2026 5:45:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 19h 45m
	Greyhound US	19h 10m	2:45 PM	Greenville, SC	Woodruff Rd	9:55 AM	Detroit	Central Bus Station		Economy	$91	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 3/26/2026 2:45:00 PM to Central Bus Station, Detroit (USA) arriving at 3/27/2026 9:55:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 19h 10m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	19h 45m	10:00 PM	Greenville, SC	Woodruff Rd	5:45 PM	Detroit	Central Bus Station		Economy	$96	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/27/2026 10:00:00 PM to Central Bus Station, Detroit (USA) arriving at 3/28/2026 5:45:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 19h 45m
	Greyhound US	19h 10m	2:45 PM	Greenville, SC	Woodruff Rd	9:55 AM	Detroit	Central Bus Station		Economy	$97	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 3/27/2026 2:45:00 PM to Central Bus Station, Detroit (USA) arriving at 3/28/2026 9:55:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 19h 10m

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	19h 45m	10:00 PM	Greenville, SC	Woodruff Rd	5:45 PM	Detroit	Central Bus Station		Economy	$92	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/28/2026 10:00:00 PM to Central Bus Station, Detroit (USA) arriving at 3/29/2026 5:45:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 19h 45m
	Greyhound US	19h 10m	2:45 PM	Greenville, SC	Woodruff Rd	9:55 AM	Detroit	Central Bus Station		Economy	$93	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 3/28/2026 2:45:00 PM to Central Bus Station, Detroit (USA) arriving at 3/29/2026 9:55:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 19h 10m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	19h 10m	2:45 PM	Greenville, SC	Woodruff Rd	9:55 AM	Detroit	Central Bus Station		Economy	$93	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 3/29/2026 2:45:00 PM to Central Bus Station, Detroit (USA) arriving at 3/30/2026 9:55:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 19h 10m
	FlixBus	19h 45m	10:00 PM	Greenville, SC	Woodruff Rd	5:45 PM	Detroit	Central Bus Station		Economy	$93	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 3/29/2026 10:00:00 PM to Central Bus Station, Detroit (USA) arriving at 3/30/2026 5:45:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 19h 45m

Best Price Offer: The price for the cheapest bus from Greenville, SC to Detroit is $79 on 4/9/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Greenville, SC and Detroit

See here how frequent the connections between Greenville, SC and Detroit are, during different times and days of the week.

Sunday is the busiest day, with more than 4 daily buses from Greenville, SC to Detroit. Friday has instead the fewest connections, with only 2 daily coaches between Greenville, SC and Detroit.

The busiest time of the day is the Afternoon, with 8 buses from Greenville, SC to Detroit, while Afternoon sees the fewest connections between Greenville, SC and Detroit, with 8 offers.

Facts about the bus from Greenville, SC to Detroit

Compare all providers like FlixBus and Greyhound US that travel 3 times every day by bus from Greenville, SC to Detroit in one click! Book your bus ticket from Greenville, SC to Detroit starting from $79!

Cheapest Bus	$79
Fastest Bus	19h 10m
Earliest Bus	2:45 PM
Latest Bus	10:00 PM
Daily Bus Routes	3 Ø
Distance	518.2 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Greenville, SC to Detroit

Every day, 3 buses from 2 bus companies leave Greenville, SC for Detroit: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/24/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/22

Monday 03/23

Tuesday 03/24

Wednesday 03/25

$87

Thursday 03/26

$90

Friday 03/27

$96

Saturday 03/28

$92

Sunday 03/29

$93

Monday 03/30

Tuesday 03/31

$98

Wednesday 04/01

Thursday 04/02

$80

Friday 04/03

Saturday 04/04

Sunday 04/05

$87

Monday 04/06

$82

Tuesday 04/07

$84

Wednesday 04/08

$88

Thursday 04/09

$79

Friday 04/10

$98

Saturday 04/11

$105

Sunday 04/12

Monday 04/13

$84

Tuesday 04/14

Wednesday 04/15

$94

Thursday 04/16

$84

Friday 04/17

$93

Saturday 04/18

The cheapest time to travel from Greenville, SC to Detroit

See here on which day and which time of the day you can find the cheapest bus ticket from Greenville, SC to Detroit, for the next 30 days.

With a price starting from $79, Thursday is the cheapest day for a bus from Greenville, SC to Detroit. Friday instead is the most expensive day with prices starting from $93.

Evening is the cheapest day time for bus tickets from Greenville, SC to Detroit, with $87. Afternoon is the most expensive time of the day with prices starting from $88.

How to save money travelling from Greenville, SC to Detroit

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Greenville, SC to Detroit in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to Detroit, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to Detroit are also emptier.

All bus stations and stops in Greenville, SC and Detroit

In the map below, you can see where to find all bus stations in Greenville, SC and Detroit.

McDonald's

Woodruff Rd 1111

Woodruff Rd

Woodruff Rd 1116

Greyhound Bus Station

Hendrix Dr 9

N Church St

Guadalajara Supermarket

White Horse Rd 2803

Central Bus Station

Howard St 1001

Amtrak

W Baltimore Ave 78

VA Medical Center Blue Deck

East Canfield Street (between John R. and Brush St.) 225

Park Avenue

Rosa Parks TC

Cass Ave 1310

Service and Comfort on the bus from Greenville, SC to Detroit

Want to know which seat classes are available on the buses from Greenville, SC to Detroit? Or which bus companies serve the route Greenville, SC to Detroit? Below you will find answers to your questions.

FAQs about the Greenville, SC to Detroit bus

How much does a Greenville, SC Detroit bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $79 and takes 19h 45m to reach Detroit. Compare offers to save money!

How much could I save by comparing buses from Greenville, SC to Detroit?

This route is offered by 2 companies with a range of ticket prices between $79 and $108. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Detroit.

On average, how many connections are available from Greenville, SC to Detroit each day?

Every day, the Greenville, SC to Detroit bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Greenville, SC to Detroit take?

The fastest bus from Greenville, SC to Detroit is offered by Greyhound US and takes 19h 10m. Bus tickets for this connection cost $91. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Greenville, SC to Detroit?

The earliest bus arriving in Detroit from Greenville, SC starts at 2:45 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Greenville, SC to Detroit?

The latest bus trip departing from Greenville, SC for Detroit starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Greenville, SC Detroit route?

When traveling by bus from Greenville, SC to Detroit, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Greenville, SC and Detroit?

You can check all the direct connections between Greenville, SC and Detroit by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Greenville, SC to Detroit bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC Detroit bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Greenville, SC Detroit bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to Detroit on your planned travel date.

How does CheckMyBus find the best bus deals from Greenville, SC to Detroit?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Greenville, SC and Detroit. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Greenville, SC to Detroit?

Prices and availability for 3 trips between Greenville, SC and Detroit change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Greenville, SC to Detroit

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Greenville, SC and to Detroit

Here’s an overview of the most popular bus routes to Greenville, SC and to Detroit. Simply click on the connection of your choice, and you will find all the details about your bus route!