Bus from Houston to Greenville, SC from $122

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Compare all timetables for the bus from Houston to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Houston to Greenville, SC from various bus operators like FlixBus, Greyhound US or Valley Transit for the next days.

today
tomorrow
$161
Wednesday
$131
Thursday
Friday
$174
Saturday
Sunday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 55m 10:00 PM Houston Harrisburg Blvd Station 9:55 PM Greenville, SC Woodruff Rd  Economy $161
Greyhound US 25h 5m 5:00 AM Houston Harrisburg Blvd Station 7:05 AM Greenville, SC Woodruff Rd  Economy $173
FlixBus 38h 20m 6:35 AM Houston SW Agencia Autobuses 9:55 PM Greenville, SC Woodruff Rd  Economy $178
FlixBus 34h 15m 7:50 PM Houston Uptown/Upper Kirby 7:05 AM Greenville, SC Woodruff Rd  Economy $180
Greyhound US 20h 35m 1:05 PM Houston Harrisburg Blvd Station 10:40 AM Greenville, SC Woodruff Rd  Economy $187
  • Did you know that if you travel from Houston to Greenville, SC via Atlanta, GA, you can save more than $46? You can find the corresponding connections below.
    • Busbud
      25h 5m
      0
      5:00 AM
      Houston
      Harrisburg Blvd Station
      10:55 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $87
      • Waiting Time 5h 45m
    • Busbud
      2h 25m
      0
      4:40 AM
      Atlanta, GA
      Garnett Transit Station
      7:05 AM
      Greenville, SC
      Woodruff Rd
      0
      Busbud
      Economy
      $28
    Travel time is 3h 30m longer, but you will save $46

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 25h 5m 5:00 AM Houston Harrisburg Blvd Station 7:05 AM Greenville, SC Woodruff Rd  Economy $131
Greyhound US 20h 35m 1:05 PM Houston Harrisburg Blvd Station 10:40 AM Greenville, SC Woodruff Rd  Economy $131
FlixBus 31h 5m 1:50 PM Houston Uptown/Upper Kirby 9:55 PM Greenville, SC Woodruff Rd  Economy $131
FlixBus 25h 0m 8:40 AM Houston Uptown/Upper Kirby 10:40 AM Greenville, SC Woodruff Rd  Economy $132
Valley Transit 38h 20m 6:35 AM Houston SW Agencia Autobuses 9:55 PM Greenville, SC Woodruff Rd  Economy $142
  • Did you know that if you travel from Houston to Greenville, SC via Atlanta, GA, you can save more than $16? You can find the corresponding connections below.
    • Busbud
      25h 5m
      0
      5:00 AM
      Houston
      Harrisburg Blvd Station
      10:55 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $87
      • Waiting Time 5h 45m
    • Busbud
      2h 25m
      0
      4:40 AM
      Atlanta, GA
      Garnett Transit Station
      7:05 AM
      Greenville, SC
      Woodruff Rd
      0
      Busbud
      Economy
      $28
    Travel time is 3h 30m longer, but you will save $16

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 25h 5m 5:00 AM Houston Harrisburg Blvd Station 7:05 AM Greenville, SC Woodruff Rd  Economy $174
Greyhound US 22h 55m 10:00 PM Houston Harrisburg Blvd Station 9:55 PM Greenville, SC Woodruff Rd  Economy $174
FlixBus 38h 20m 6:35 AM Houston SW Agencia Autobuses 9:55 PM Greenville, SC Woodruff Rd  Economy $186
FlixBus 31h 15m 10:50 PM Houston Downtown Houston 7:05 AM Greenville, SC Woodruff Rd  Economy $186
Greyhound US 20h 35m 1:05 PM Houston Harrisburg Blvd Station 10:40 AM Greenville, SC Woodruff Rd  Economy $188
  • Did you know that if you travel from Houston to Greenville, SC via Atlanta, GA, you can save more than $59? You can find the corresponding connections below.
    • Busbud
      25h 5m
      0
      5:00 AM
      Houston
      Harrisburg Blvd Station
      10:55 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $87
      • Waiting Time 5h 45m
    • Busbud
      2h 25m
      0
      4:40 AM
      Atlanta, GA
      Garnett Transit Station
      7:05 AM
      Greenville, SC
      Woodruff Rd
      0
      Busbud
      Economy
      $28
    Travel time is 3h 30m longer, but you will save $59

Best Price Offer: The price for the cheapest bus from Houston to Greenville, SC is $122 on 1/12/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Houston and Greenville, SC

See here how frequent the connections between Houston and Greenville, SC are, during different times and days of the week.
Wednesday is the busiest day, with more than 18 daily buses from Houston to Greenville, SC. Tuesday has instead the fewest connections, with only 8 daily coaches between Houston and Greenville, SC.
The busiest time of the day is the Afternoon, with 12 buses from Houston to Greenville, SC, while Night sees the fewest connections between Houston and Greenville, SC, with 4 offers.

Facts about the bus from Houston to Greenville, SC

Compare all providers like FlixBus, Greyhound US and Valley Transit that travel 12 times every day by bus from Houston to Greenville, SC in one click! Book your bus ticket from Houston to Greenville, SC starting from $122!

Cheapest Bus $122
Fastest Bus 20h 55m
Earliest Bus 5:00 AM
Latest Bus 10:50 PM
Daily Bus Routes 12 Ø
Distance 835.2 miles
Bus Companies FlixBus, Greyhound US and Valley Transit

Cheapest bus connections from Houston to Greenville, SC

Every day, 12 buses from 3 bus companies leave Houston for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/22/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/21
Monday 12/22
Tuesday 12/23
$161
Wednesday 12/24
$168
Thursday 12/25
Friday 12/26
$174
Saturday 12/27
Sunday 12/28
Monday 12/29
Tuesday 12/30
Wednesday 12/31
Thursday 01/01
Friday 01/02
Saturday 01/03
Sunday 01/04
Monday 01/05
Tuesday 01/06
Wednesday 01/07
Thursday 01/08
Friday 01/09
Saturday 01/10
Sunday 01/11
Monday 01/12
$122
Tuesday 01/13
Wednesday 01/14
Thursday 01/15
Friday 01/16
Saturday 01/17

The cheapest time to travel from Houston to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to Greenville, SC, for the next 30 days.
With a price starting from $131, Wednesday is the cheapest day for a bus from Houston to Greenville, SC. Friday instead is the most expensive day with prices starting from $174.
Night is the cheapest day time for bus tickets from Houston to Greenville, SC, with $122. Morning is the most expensive time of the day with prices starting from $132.

How to save money travelling from Houston to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to Greenville, SC are also emptier.

All bus stations and stops in Houston and Greenville, SC

In the map below, you can see where to find all bus stations in Houston and Greenville, SC.

Service and Comfort on the bus from Houston to Greenville, SC

Want to know which seat classes are available on the buses from Houston to Greenville, SC? Or which bus companies serve the route Houston to Greenville, SC? Below you will find answers to your questions.

FAQs about the Houston to Greenville, SC bus

How much does a Houston Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $122 and takes 32h 5m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Houston to Greenville, SC?

This route is offered by 3 companies with a range of ticket prices between $122 and $215. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Houston to Greenville, SC each day?

Every day, the Houston to Greenville, SC bus route is served by approximately 12 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to Greenville, SC take?

The fastest bus from Houston to Greenville, SC is offered by FlixBus and takes 20h 55m. Bus tickets for this connection cost $190. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to Greenville, SC?

The earliest bus arriving in Greenville, SC from Houston starts at 5:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to Greenville, SC?

The latest bus trip departing from Houston for Greenville, SC starts at 10:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston Greenville, SC route?

When traveling by bus from Houston to Greenville, SC, passengers can travel with FlixBus, Greyhound US and Valley Transit. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and Greenville, SC?

You can check all the direct connections between Houston and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Valley Transit.

What can I take with me on the Houston to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to Greenville, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Houston to Greenville, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 12 daily trips between Houston and Greenville, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Houston to Greenville, SC?

Prices and availability for 12 trips between Houston and Greenville, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Houston to Greenville, SC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to Greenville, SC

Here’s an overview of the most popular bus routes to Houston and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Houston and to Greenville, SC
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