Bus from Philadelphia to Greenville, SC from $68

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Compare all timetables for the bus from Philadelphia to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Philadelphia to Greenville, SC from various bus operators like FlixBus or Greyhound US for the next days.
today
tomorrow
from $79
Friday
Saturday
from $68
Sunday
from $77
Monday
from $89
Tuesday

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    17h 20m
    0
    3:20 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    8:40 AM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $79
  • FlixBus
    22h 20m
    0
    10:20 AM
    Philadelphia
    JFK & Broad
    8:40 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $80
  • Greyhound US
    14h 20m
    0
    8:30 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    10:50 AM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $81
  • FlixBus
    14h 15m
    0
    6:25 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    8:40 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $86
  • Greyhound US
    17h 55m
    0
    2:45 PM
    Philadelphia
    IRS Building
    8:40 AM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $87

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    22h 0m
    0
    9:30 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    7:30 PM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $68
  • Greyhound US
    19h 20m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    3:20 PM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $68
  • FlixBus
    16h 20m
    0
    3:10 AM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    7:30 PM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $69
  • FlixBus
    18h 30m
    0
    6:45 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    1:15 PM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $69
  • Greyhound US
    17h 55m
    0
    2:45 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    8:40 AM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $70

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    16h 20m
    0
    3:10 AM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    7:30 PM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $77
  • FlixBus
    14h 15m
    0
    6:25 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    8:40 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $78
  • FlixBus
    22h 0m
    0
    9:30 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    7:30 PM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $78
  • Greyhound US
    17h 55m
    0
    2:45 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    8:40 AM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $78
  • Greyhound US
    19h 20m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    3:20 PM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $78

Cheapest bus trips Monday

Prices are for one way and one person
  • Greyhound US
    17h 0m
    0
    5:55 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    10:55 AM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $89
  • FlixBus
    22h 10m
    0
    9:30 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    7:40 PM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $93
  • Greyhound US
    19h 20m
    0
    8:00 PM
    Philadelphia
    IRS Building
    3:20 PM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $93
  • Greyhound US
    14h 20m
    0
    8:30 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    10:50 AM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $94
  • FlixBus
    18h 30m
    0
    6:45 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    1:15 PM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $97

Frequency of bus connections between Philadelphia and Greenville, SC

See here how frequent the connections between Philadelphia and Greenville, SC are, during different times and days of the week.
Sunday is the busiest day, with more than 22 daily buses from Philadelphia to Greenville, SC. Thursday has instead the fewest connections, with only 9 daily coaches between Philadelphia and Greenville, SC.
The busiest time of the day is the Evening, with 34 buses from Philadelphia to Greenville, SC, while Morning sees the fewest connections between Philadelphia and Greenville, SC, with 2 offers.

Facts about the bus from Philadelphia to Greenville, SC

Compare all providers like FlixBus and Greyhound US that travel 15 times every day by bus from Philadelphia to Greenville, SC in one click! Book your bus ticket from Philadelphia to Greenville, SC starting from $68!

Cheapest Bus $68
Fastest Bus 14h 15m
Earliest Bus 10:20 AM
Latest Bus 9:30 PM
Daily Bus Routes 15 Ø
Distance 530.0 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Philadelphia to Greenville, SC

Every day, 15 buses from 2 bus companies leave Philadelphia for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/14/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/11
Monday 05/12
Tuesday 05/13
Wednesday 05/14
Thursday 05/15
$79
Friday 05/16
Saturday 05/17
$81
Sunday 05/18
$77
Monday 05/19
$89
Tuesday 05/20
Wednesday 05/21
Thursday 05/22
$101
Friday 05/23
Saturday 05/24
$89
Sunday 05/25
$80
Monday 05/26
Tuesday 05/27
Wednesday 05/28
Thursday 05/29
Friday 05/30
Saturday 05/31
$79
Sunday 06/01
Monday 06/02
Tuesday 06/03
Wednesday 06/04
$63
Thursday 06/05
Friday 06/06
Saturday 06/07

The cheapest time to travel from Philadelphia to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Philadelphia to Greenville, SC, for the next 30 days.
With a price starting from $68, Saturday is the cheapest day for a bus from Philadelphia to Greenville, SC. Monday instead is the most expensive day with prices starting from $89.
Evening is the cheapest day time for bus tickets from Philadelphia to Greenville, SC, with $68. Morning is the most expensive time of the day with prices starting from $80.

How to save money travelling from Philadelphia to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Philadelphia to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Philadelphia to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Philadelphia to Greenville, SC are also emptier.

Beloved bus companies from Philadelphia to Greenville, SC

These are the most booked bus companies between Philadelphia to Greenville, SC from our users.

Greyhound US from Philadelphia to Greenville, SC

Greyhound US

Here you will find the key facts about the Greyhound US bus route Philadelphia to Greenville, SC:

Cheapest Price $68
Fastest Bus 14h 20m
Earliest Bus 2:45 PM
Last Bus 8:30 PM
Daily Connections 7 Ø
Found on 5/10/2025

All bus stations and stops in Philadelphia and Greenville, SC

In the map below, you can see where to find all bus stations in Philadelphia and Greenville, SC.

Service and Comfort on the bus from Philadelphia to Greenville, SC

Want to know which seat classes are available on the buses from Philadelphia to Greenville, SC? Or which bus companies serve the route Philadelphia to Greenville, SC? Below you will find answers to your questions.

FAQs about the Philadelphia to Greenville, SC bus

How much does a Philadelphia Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $68 and takes 22h 0m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Philadelphia to Greenville, SC?

This route is offered by 2 companies with a range of ticket prices between $68 and $111. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Philadelphia to Greenville, SC each day?

Every day, the Philadelphia to Greenville, SC bus route is served by approximately 15 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Philadelphia to Greenville, SC take?

The fastest bus from Philadelphia to Greenville, SC is offered by FlixBus and takes 14h 15m. Bus tickets for this connection cost $86. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Philadelphia to Greenville, SC?

The earliest bus arriving in Greenville, SC from Philadelphia starts at 10:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Philadelphia to Greenville, SC?

The latest bus trip departing from Philadelphia for Greenville, SC starts at 9:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Philadelphia Greenville, SC route?

When traveling by bus from Philadelphia to Greenville, SC, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Philadelphia and Greenville, SC?

You can check all the direct connections between Philadelphia and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Philadelphia to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Philadelphia Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Philadelphia Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Philadelphia to Greenville, SC on your planned travel date.

Available seat classes which are offered on the bus route Philadelphia to Greenville, SC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Philadelphia and to Greenville, SC

Here’s an overview of the most popular bus routes to Philadelphia and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from New York to Philadelphia Bus from New York to Philadelphia
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Bus Boston, MA to Philadelphia Bus Boston, MA to Philadelphia
Bus to Greenville, SC from Atlanta, GA Bus to Greenville, SC from Atlanta, GA
Bus from Jacksonville, FL to Greenville, SC Bus from Jacksonville, FL to Greenville, SC
Bus to Greenville, SC from Charlotte Bus to Greenville, SC from Charlotte
Buses to Greenville, SC from Orlando, FL Buses to Greenville, SC from Orlando, FL
Popular Airport Shuttles to Philadelphia and to Greenville, SC
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