Which bus from Durham, NC to Greenville, SC is the cheapest?

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Compare all timetables for the bus from Durham, NC to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Durham, NC to Greenville, SC from various bus operators like Wanda Coach, FlixBus or Greyhound US for the next days.

today
$41
tomorrow
$50
Tuesday
$50
Wednesday
$50
Thursday
Friday
$41
Saturday
$50

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 4h 45m 8:30 AM Durham, NC Exxon 1:15 PM Greenville, SC Woodruff Rd  Economy $41
FlixBus 4h 45m 2:40 PM Durham, NC Exxon 7:25 PM Greenville, SC Woodruff Rd  Economy $43

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Wanda Coach 4h 40m 1:30 AM Durham, NC BP Guess Road 6:10 AM Greenville, SC McDonald's  Economy $50
Wanda Coach 4h 40m 4:20 AM Durham, NC BP Guess Road 9:00 AM Greenville, SC McDonald's  Economy $50

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Wanda Coach 4h 40m 1:30 AM Durham, NC BP Guess Road 6:10 AM Greenville, SC McDonald's  Economy $50
Wanda Coach 4h 40m 4:20 AM Durham, NC BP Guess Road 9:00 AM Greenville, SC McDonald's  Economy $50
  • Did you know that if you travel from Durham, NC to Greenville, SC via Winston-Salem, NC, you can save more than $14? You can find the corresponding connections below.
    • Greyhound US
      5h 55m
      0
      4:55 AM
      Durham, NC
      Exxon
      6:45 AM
      Winston-Salem, NC
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $14
      • Waiting Time 0h 10m
    • Greyhound US
      3h 55m
      0
      6:55 AM
      Winston-Salem, NC
      Greyhound Bus Station
      10:50 AM
      Greenville, SC
      Woodruff Rd
      0
      Greyhound US
      Economy
      $22
    Travel time is 1h 15m longer, but you will save $14

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Wanda Coach 4h 40m 1:30 AM Durham, NC BP Hillandale Rd 6:10 AM Greenville, SC McDonald's  Economy $50
Wanda Coach 4h 40m 4:20 AM Durham, NC BP Hillandale Rd 9:00 AM Greenville, SC McDonald's  Economy $50
  • Did you know that if you travel from Durham, NC to Greenville, SC via Winston-Salem, NC, you can save more than $14? You can find the corresponding connections below.
    • Greyhound US
      5h 55m
      0
      4:55 AM
      Durham, NC
      Exxon
      6:45 AM
      Winston-Salem, NC
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $14
      • Waiting Time 0h 10m
    • Greyhound US
      3h 55m
      0
      6:55 AM
      Winston-Salem, NC
      Greyhound Bus Station
      10:50 AM
      Greenville, SC
      Woodruff Rd
      0
      Greyhound US
      Economy
      $22
    Travel time is 1h 15m longer, but you will save $14

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 4h 40m 3:55 AM Durham, NC Exxon 8:35 AM Greenville, SC Woodruff Rd  Economy $41
FlixBus 4h 45m 8:30 AM Durham, NC Exxon 1:15 PM Greenville, SC Woodruff Rd  Economy $41
Greyhound US 5h 55m 4:55 AM Durham, NC Exxon 10:50 AM Greenville, SC Woodruff Rd  Economy $43
Wanda Coach 4h 40m 1:30 AM Durham, NC BP Hillandale Rd 6:10 AM Greenville, SC McDonald's  Economy $50
Wanda Coach 4h 40m 4:20 AM Durham, NC BP Hillandale Rd 9:00 AM Greenville, SC McDonald's  Economy $50
  • Did you know that if you travel from Durham, NC to Greenville, SC via Winston-Salem, NC, you can save more than $5? You can find the corresponding connections below.
    • Greyhound US
      5h 55m
      0
      4:55 AM
      Durham, NC
      Exxon
      6:45 AM
      Winston-Salem, NC
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $14
      • Waiting Time 0h 10m
    • Greyhound US
      3h 55m
      0
      6:55 AM
      Winston-Salem, NC
      Greyhound Bus Station
      10:50 AM
      Greenville, SC
      Woodruff Rd
      0
      Greyhound US
      Economy
      $22
    Travel time is 1h 15m longer, but you will save $5

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Wanda Coach 4h 40m 1:30 AM Durham, NC BP Guess Road 6:10 AM Greenville, SC McDonald's  Economy $50
Wanda Coach 4h 40m 4:20 AM Durham, NC BP Guess Road 9:00 AM Greenville, SC McDonald's  Economy $50
  • Did you know that if you travel from Durham, NC to Greenville, SC via Winston-Salem, NC, you can save more than $14? You can find the corresponding connections below.
    • Greyhound US
      5h 55m
      0
      4:55 AM
      Durham, NC
      Exxon
      6:45 AM
      Winston-Salem, NC
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $14
      • Waiting Time 0h 10m
    • Greyhound US
      3h 55m
      0
      6:55 AM
      Winston-Salem, NC
      Greyhound Bus Station
      10:50 AM
      Greenville, SC
      Woodruff Rd
      0
      Greyhound US
      Economy
      $22
    Travel time is 1h 15m longer, but you will save $14

Best Price Offer: The price for the cheapest bus from Durham, NC to Greenville, SC is $37 on 4/9/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Durham, NC and Greenville, SC

See here how frequent the connections between Durham, NC and Greenville, SC are, during different times and days of the week.
Friday is the busiest day, with more than 6 daily buses from Durham, NC to Greenville, SC. Sunday has instead the fewest connections, with only 2 daily coaches between Durham, NC and Greenville, SC.
The busiest time of the day is the Night, with 12 buses from Durham, NC to Greenville, SC, while Morning sees the fewest connections between Durham, NC and Greenville, SC, with 2 offers.

Facts about the bus from Durham, NC to Greenville, SC

Compare all providers like Wanda Coach, FlixBus and Greyhound US that travel 2 times every day by bus from Durham, NC to Greenville, SC in one click! Book your bus ticket from Durham, NC to Greenville, SC starting from $37!

Cheapest Bus $37
Fastest Bus 4h 40m
Earliest Bus 8:30 AM
Latest Bus 4:20 AM
Daily Bus Routes 2 Ø
Distance 211.7 miles
Bus Companies Wanda Coach, FlixBus and Greyhound US

Cheapest bus connections from Durham, NC to Greenville, SC

Every day, 2 buses from 3 bus companies leave Durham, NC for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/22/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/22
$41
Monday 03/23
$50
Tuesday 03/24
$50
Wednesday 03/25
$50
Thursday 03/26
Friday 03/27
$50
Saturday 03/28
$50
Sunday 03/29
$44
Monday 03/30
$50
Tuesday 03/31
$50
Wednesday 04/01
Thursday 04/02
$50
Friday 04/03
$50
Saturday 04/04
Sunday 04/05
$50
Monday 04/06
$50
Tuesday 04/07
$41
Wednesday 04/08
$38
Thursday 04/09
$37
Friday 04/10
$38
Saturday 04/11
$50
Sunday 04/12
$50
Monday 04/13
$50
Tuesday 04/14
$50
Wednesday 04/15
$50
Thursday 04/16
$50
Friday 04/17
$41
Saturday 04/18

The cheapest time to travel from Durham, NC to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Durham, NC to Greenville, SC, for the next 30 days.
With a price starting from $38, Wednesday is the cheapest day for a bus from Durham, NC to Greenville, SC. Monday instead is the most expensive day with prices starting from $50.
Night is the cheapest day time for bus tickets from Durham, NC to Greenville, SC, with $37. Afternoon is the most expensive time of the day with prices starting from $41.

How to save money travelling from Durham, NC to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Durham, NC to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Durham, NC to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Durham, NC to Greenville, SC are also emptier.

All bus stations and stops in Durham, NC and Greenville, SC

In the map below, you can see where to find all bus stations in Durham, NC and Greenville, SC.

Service and Comfort on the bus from Durham, NC to Greenville, SC

Want to know which seat classes are available on the buses from Durham, NC to Greenville, SC? Or which bus companies serve the route Durham, NC to Greenville, SC? Below you will find answers to your questions.

FAQs about the Durham, NC to Greenville, SC bus

How much does a Durham, NC Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $37 and takes 4h 45m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Durham, NC to Greenville, SC?

This route is offered by 3 companies with a range of ticket prices between $37 and $50. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Durham, NC to Greenville, SC each day?

Every day, the Durham, NC to Greenville, SC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Durham, NC to Greenville, SC take?

The fastest bus from Durham, NC to Greenville, SC is offered by Wanda Coach and takes 4h 40m. Bus tickets for this connection cost $50. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Durham, NC to Greenville, SC?

The earliest bus arriving in Greenville, SC from Durham, NC starts at 8:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Durham, NC to Greenville, SC?

The latest bus trip departing from Durham, NC for Greenville, SC starts at 4:20 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Durham, NC Greenville, SC route?

When traveling by bus from Durham, NC to Greenville, SC, passengers can travel with Wanda Coach, FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Durham, NC and Greenville, SC?

You can check all the direct connections between Durham, NC and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Wanda Coach, FlixBus and Greyhound US.

What can I take with me on the Durham, NC to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Durham, NC Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Durham, NC Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Durham, NC to Greenville, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Durham, NC to Greenville, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Durham, NC and Greenville, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Durham, NC to Greenville, SC?

Prices and availability for 2 trips between Durham, NC and Greenville, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Durham, NC to Greenville, SC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Durham, NC and to Greenville, SC

Here’s an overview of the most popular bus routes to Durham, NC and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Durham, NC and to Greenville, SC
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