Bus from Lexington, KY to Greenville, SC from $67

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Lexington, KY to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Lexington, KY to Greenville, SC from various bus operators like Greyhound US for the next days.

today
$90
tomorrow
$93
Wednesday
$80
Thursday
$77
Friday
$75
Saturday
$73
Sunday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 15m 3:45 PM Lexington, KY Greyhound Bus Station 7:00 AM Greenville, SC Woodruff Rd  Economy $90
  • Did you know that if you travel from Lexington, KY to Greenville, SC via Atlanta, GA, you can save more than $25? You can find the corresponding connections below.
    • Greyhound US
      15h 15m
      0
      3:45 PM
      Lexington, KY
      Greyhound Bus Station
      11:35 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $42
      • Waiting Time 5h 5m
    • Greyhound US
      2h 20m
      0
      4:40 AM
      Atlanta, GA
      Garnett Transit Station
      7:00 AM
      Greenville, SC
      Woodruff Rd
      0
      Greyhound US
      Economy
      $23
    Travel time is the same as the direct connection, but you will save $25

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 15m 3:45 PM Lexington, KY Greyhound Bus Station 7:00 AM Greenville, SC Woodruff Rd  Economy $93
  • Did you know that if you travel from Lexington, KY to Greenville, SC via Atlanta, GA, you can save more than $28? You can find the corresponding connections below.
    • Greyhound US
      15h 15m
      0
      3:45 PM
      Lexington, KY
      Greyhound Bus Station
      11:35 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $42
      • Waiting Time 5h 5m
    • Greyhound US
      2h 20m
      0
      4:40 AM
      Atlanta, GA
      Garnett Transit Station
      7:00 AM
      Greenville, SC
      Woodruff Rd
      0
      Greyhound US
      Economy
      $23
    Travel time is the same as the direct connection, but you will save $28

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 15m 3:45 PM Lexington, KY Greyhound Bus Station 7:00 AM Greenville, SC Woodruff Rd  Economy $80
  • Did you know that if you travel from Lexington, KY to Greenville, SC via Atlanta, GA, you can save more than $15? You can find the corresponding connections below.
    • Greyhound US
      15h 15m
      0
      3:45 PM
      Lexington, KY
      Greyhound Bus Station
      11:35 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $42
      • Waiting Time 5h 5m
    • Greyhound US
      2h 20m
      0
      4:40 AM
      Atlanta, GA
      Garnett Transit Station
      7:00 AM
      Greenville, SC
      Woodruff Rd
      0
      Greyhound US
      Economy
      $23
    Travel time is the same as the direct connection, but you will save $15

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 15m 3:45 PM Lexington, KY Greyhound Bus Station 7:00 AM Greenville, SC Woodruff Rd  Economy $77
  • Did you know that if you travel from Lexington, KY to Greenville, SC via Atlanta, GA, you can save more than $12? You can find the corresponding connections below.
    • Greyhound US
      15h 15m
      0
      3:45 PM
      Lexington, KY
      Greyhound Bus Station
      11:35 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $42
      • Waiting Time 5h 5m
    • Greyhound US
      2h 20m
      0
      4:40 AM
      Atlanta, GA
      Garnett Transit Station
      7:00 AM
      Greenville, SC
      Woodruff Rd
      0
      Greyhound US
      Economy
      $23
    Travel time is the same as the direct connection, but you will save $12

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 15m 3:45 PM Lexington, KY Greyhound Bus Station 7:00 AM Greenville, SC Woodruff Rd  Economy $75
  • Did you know that if you travel from Lexington, KY to Greenville, SC via Atlanta, GA, you can save more than $10? You can find the corresponding connections below.
    • Greyhound US
      15h 15m
      0
      3:45 PM
      Lexington, KY
      Greyhound Bus Station
      11:35 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $42
      • Waiting Time 5h 5m
    • Greyhound US
      2h 20m
      0
      4:40 AM
      Atlanta, GA
      Garnett Transit Station
      7:00 AM
      Greenville, SC
      Woodruff Rd
      0
      Greyhound US
      Economy
      $23
    Travel time is the same as the direct connection, but you will save $10

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 15m 3:45 PM Lexington, KY Greyhound Bus Station 7:00 AM Greenville, SC Woodruff Rd  Economy $73
  • Did you know that if you travel from Lexington, KY to Greenville, SC via Atlanta, GA, you can save more than $8? You can find the corresponding connections below.
    • Greyhound US
      15h 15m
      0
      3:45 PM
      Lexington, KY
      Greyhound Bus Station
      11:35 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $42
      • Waiting Time 5h 5m
    • Greyhound US
      2h 20m
      0
      4:40 AM
      Atlanta, GA
      Garnett Transit Station
      7:00 AM
      Greenville, SC
      Woodruff Rd
      0
      Greyhound US
      Economy
      $23
    Travel time is the same as the direct connection, but you will save $8

Best Price Offer: The price for the cheapest bus from Lexington, KY to Greenville, SC is $67 on 4/30/2026. Flexible travelers save on ticket prices.


Facts about the bus from Lexington, KY to Greenville, SC

Compare all providers like Greyhound US that travel 1 times every day by bus from Lexington, KY to Greenville, SC in one click! Book your bus ticket from Lexington, KY to Greenville, SC starting from $67!

Cheapest Bus $67
Fastest Bus 15h 15m
Earliest Bus 3:45 PM
Latest Bus 3:45 PM
Daily Bus Routes 1 Ø
Distance 249.6 miles
Bus Companies Greyhound US

Cheapest bus connections from Lexington, KY to Greenville, SC

Every day, 1 buses from 1 bus companies leave Lexington, KY for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/19
Monday 04/20
$90
Tuesday 04/21
$93
Wednesday 04/22
$84
Thursday 04/23
$77
Friday 04/24
$75
Saturday 04/25
$73
Sunday 04/26
Monday 04/27
$84
Tuesday 04/28
$216
Wednesday 04/29
$83
Thursday 04/30
$67
Friday 05/01
$216
Saturday 05/02
$71
Sunday 05/03
$70
Monday 05/04
$216
Tuesday 05/05
Wednesday 05/06
Thursday 05/07
Friday 05/08
Saturday 05/09
$72
Sunday 05/10
$75
Monday 05/11
$222
Tuesday 05/12
$83
Wednesday 05/13
$83
Thursday 05/14
$77
Friday 05/15
$77
Saturday 05/16

How to save money travelling from Lexington, KY to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lexington, KY to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lexington, KY to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lexington, KY to Greenville, SC are also emptier.

Beloved bus companies from Lexington, KY to Greenville, SC

These are the most booked bus companies between Lexington, KY to Greenville, SC from our users.

Greyhound US from Lexington, KY to Greenville, SC

Greyhound US

Here you will find the key facts about the Greyhound US bus route Lexington, KY to Greenville, SC:

Cheapest Price $73
Fastest Bus 15h 15m
Earliest Bus 3:45 PM
Last Bus 3:45 PM
Daily Connections 1 Ø
Found on 3/25/2026

All bus stations and stops in Lexington, KY and Greenville, SC

In the map below, you can see where to find all bus stations in Lexington, KY and Greenville, SC.

Service and Comfort on the bus from Lexington, KY to Greenville, SC

Want to know which seat classes are available on the buses from Lexington, KY to Greenville, SC? Or which bus companies serve the route Lexington, KY to Greenville, SC? Below you will find answers to your questions.

FAQs about the Lexington, KY to Greenville, SC bus

How much does a Lexington, KY Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $67 and takes 15h 15m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Lexington, KY to Greenville, SC?

This route is offered by 1 companies with a range of ticket prices between $67 and $97. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Lexington, KY to Greenville, SC each day?

Every day, the Lexington, KY to Greenville, SC bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lexington, KY to Greenville, SC take?

The fastest bus from Lexington, KY to Greenville, SC is offered by Greyhound US and takes 15h 15m. Bus tickets for this connection cost $92. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lexington, KY to Greenville, SC?

The earliest bus arriving in Greenville, SC from Lexington, KY starts at 3:45 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lexington, KY to Greenville, SC?

The latest bus trip departing from Lexington, KY for Greenville, SC starts at 3:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lexington, KY Greenville, SC route?

When traveling by bus from Lexington, KY to Greenville, SC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lexington, KY and Greenville, SC?

You can check all the direct connections between Lexington, KY and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Lexington, KY to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lexington, KY Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lexington, KY Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lexington, KY to Greenville, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Lexington, KY to Greenville, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Lexington, KY and Greenville, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Lexington, KY to Greenville, SC?

Prices and availability for 1 trips between Lexington, KY and Greenville, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Lexington, KY to Greenville, SC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lexington, KY and to Greenville, SC

Here’s an overview of the most popular bus routes to Lexington, KY and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Ontario, CA - Lexington, KY Bus Ontario, CA - Lexington, KY
Bus Brownsville, TX - Lexington, KY Bus Brownsville, TX - Lexington, KY
Buses from Laredo, TX to Lexington, KY Buses from Laredo, TX to Lexington, KY
Bus from Mobile, AL to Lexington, KY Bus from Mobile, AL to Lexington, KY
Buses Sacramento to Greenville, SC Buses Sacramento to Greenville, SC
Buses Tucson, AZ to Greenville, SC Buses Tucson, AZ to Greenville, SC
From Guadalajara, JC to Greenville, SC bus From Guadalajara, JC to Greenville, SC bus
Bus from Santiago de Queretaro to Greenville, SC Bus from Santiago de Queretaro to Greenville, SC
Popular Airport Shuttles to Lexington, KY and to Greenville, SC
CheckMyBus › Buses in USA › Bus to Lexington, KY › Bus to Greenville, SC

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.