Bus Columbia, MO to Lexington, KY - Compare all Companies

Compare all timetables for the bus from Columbia, MO to Lexington, KY

Here is a selection of the cheapest bus trips from the schedule from Columbia, MO to Lexington, KY from various bus operators like Greyhound US for the next days.

today

tomorrow

$80

Monday

$83

Tuesday

$80

Wednesday

$88

Thursday

$75

Friday

$82

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	18h 30m	8:05 PM	Columbia, MO	Bus Stop	3:35 PM	Lexington, KY	Greyhound Bus Station		Economy	$80	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/21/2026 8:05:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/22/2026 3:35:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 18h 30m
	Greyhound US	18h 0m	8:35 PM	Columbia, MO	Red Thread	3:35 PM	Lexington, KY	Greyhound Bus Station		Economy	$82	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/21/2026 8:35:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/22/2026 3:35:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 18h 0m

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	18h 30m	8:05 PM	Columbia, MO	Bus Stop	3:35 PM	Lexington, KY	Greyhound Bus Station		Economy	$83	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/22/2026 8:05:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/23/2026 3:35:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 18h 30m
	Greyhound US	18h 0m	8:35 PM	Columbia, MO	Red Thread	3:35 PM	Lexington, KY	Greyhound Bus Station		Economy	$84	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/22/2026 8:35:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/23/2026 3:35:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 18h 0m

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	18h 30m	8:05 PM	Columbia, MO	Bus Stop	3:35 PM	Lexington, KY	Greyhound Bus Station		Economy	$80	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/23/2026 8:05:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/24/2026 3:35:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 18h 30m
	Greyhound US	18h 0m	8:35 PM	Columbia, MO	Red Thread	3:35 PM	Lexington, KY	Greyhound Bus Station		Economy	$82	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/23/2026 8:35:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/24/2026 3:35:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 18h 0m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	18h 30m	8:05 PM	Columbia, MO	Bus Stop	3:35 PM	Lexington, KY	Greyhound Bus Station		Economy	$88	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/24/2026 8:05:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/25/2026 3:35:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 18h 30m
	Greyhound US	18h 0m	8:35 PM	Columbia, MO	Red Thread	3:35 PM	Lexington, KY	Greyhound Bus Station		Economy	$88	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/24/2026 8:35:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/25/2026 3:35:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 18h 0m

Did you know that if you travel from Columbia, MO to Lexington, KY via St. Louis, MO, you can save more than $11? You can find the corresponding connections below.
- Greyhound US
  
  18h 0m
  
  0
  
  8:35 PM
  
  Columbia, MO
  Red Thread
  
  10:55 PM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $23
  
  A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/24/2026 8:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/24/2026 10:55:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 2h 20m
- Greyhound US
  
  12h 35m
  
  0
  
  2:00 AM
  
  St. Louis, MO
  Gateway Station
  
  3:35 PM
  
  Lexington, KY
  Greyhound Bus Station
  
  0
  
  Economy
  
  $53
  
  A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 6/25/2026 2:00:00 AM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/25/2026 3:35:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 12h 35m
Travel Time is 1h 0m shorter, and you will save $11

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	18h 30m	8:05 PM	Columbia, MO	Bus Stop	3:35 PM	Lexington, KY	Greyhound Bus Station		Economy	$75	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/25/2026 8:05:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/26/2026 3:35:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 18h 30m
	Greyhound US	18h 0m	8:35 PM	Columbia, MO	Red Thread	3:35 PM	Lexington, KY	Greyhound Bus Station		Economy	$75	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/25/2026 8:35:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/26/2026 3:35:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 18h 0m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	18h 30m	8:05 PM	Columbia, MO	Bus Stop	3:35 PM	Lexington, KY	Greyhound Bus Station		Economy	$82	A Bus from Greyhound US goes from Bus Stop, Columbia, MO (USA) at 6/26/2026 8:05:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/27/2026 3:35:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 18h 30m
	Greyhound US	18h 0m	8:35 PM	Columbia, MO	Red Thread	3:35 PM	Lexington, KY	Greyhound Bus Station		Economy	$82	A Bus from Greyhound US goes from Red Thread, Columbia, MO (USA) at 6/26/2026 8:35:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 6/27/2026 3:35:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 18h 0m

Best Price Offer: The price for the cheapest bus from Columbia, MO to Lexington, KY is $75 on 6/14/2026. Flexible travelers save on ticket prices.

Facts about the bus from Columbia, MO to Lexington, KY

Compare all providers like Greyhound US that travel 2 times every day by bus from Columbia, MO to Lexington, KY in one click! Book your bus ticket from Columbia, MO to Lexington, KY starting from $75!

Cheapest Bus	$75
Fastest Bus	19h 0m
Earliest Bus	8:05 PM
Latest Bus	8:35 PM
Daily Bus Routes	2 Ø
Distance	427.9 miles
Bus Companies	Greyhound US

Cheapest bus connections from Columbia, MO to Lexington, KY

Every day, 2 buses from 1 bus companies leave Columbia, MO for Lexington, KY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/14

Monday 06/15

Tuesday 06/16

Wednesday 06/17

Thursday 06/18

Friday 06/19

Saturday 06/20

Sunday 06/21

$84

Monday 06/22

$83

Tuesday 06/23

$80

Wednesday 06/24

$88

Thursday 06/25

$75

Friday 06/26

$82

Saturday 06/27

Sunday 06/28

$86

Monday 06/29

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

Friday 07/03

Saturday 07/04

Sunday 07/05

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

Friday 07/10

Saturday 07/11

How to save money travelling from Columbia, MO to Lexington, KY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Columbia, MO to Lexington, KY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Columbia, MO to Lexington, KY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Columbia, MO to Lexington, KY are also emptier.

All bus stations and stops in Columbia, MO and Lexington, KY

In the map below, you can see where to find all bus stations in Columbia, MO and Lexington, KY.

Bus Stop

N 10th St 198

Red Thread

Highway 40 W 6401

University

Fellows Pl 1301-1349

University of Kentucky

Rose St 505

Buena Vista Road

Greyhound Bus Station

W New Circle Rd Nw 477

N Broadway

N Broadway 1949

Alexandria Dr

Alexandria Dr 1801

Service and Comfort on the bus from Columbia, MO to Lexington, KY

Want to know which seat classes are available on the buses from Columbia, MO to Lexington, KY? Or which bus companies serve the route Columbia, MO to Lexington, KY? Below you will find answers to your questions.

FAQs about the Columbia, MO to Lexington, KY bus

How much does a Columbia, MO Lexington, KY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $75 and takes 19h 0m to reach Lexington, KY. Compare offers to save money!

How much could I save by comparing buses from Columbia, MO to Lexington, KY?

This route is offered by 1 companies with a range of ticket prices between $75 and $88. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lexington, KY.

On average, how many connections are available from Columbia, MO to Lexington, KY each day?

Every day, the Columbia, MO to Lexington, KY bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Columbia, MO to Lexington, KY take?

The fastest bus from Columbia, MO to Lexington, KY is offered by Greyhound US and takes 19h 0m. Bus tickets for this connection cost $82. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Columbia, MO to Lexington, KY?

The earliest bus arriving in Lexington, KY from Columbia, MO starts at 8:05 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Columbia, MO to Lexington, KY?

The latest bus trip departing from Columbia, MO for Lexington, KY starts at 8:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Columbia, MO Lexington, KY route?

When traveling by bus from Columbia, MO to Lexington, KY, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Columbia, MO and Lexington, KY?

You can check all the direct connections between Columbia, MO and Lexington, KY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Columbia, MO to Lexington, KY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Columbia, MO Lexington, KY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Columbia, MO Lexington, KY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Columbia, MO to Lexington, KY on your planned travel date.

How does CheckMyBus find the best bus deals from Columbia, MO to Lexington, KY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Columbia, MO and Lexington, KY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Columbia, MO to Lexington, KY?

Prices and availability for 2 trips between Columbia, MO and Lexington, KY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Columbia, MO to Lexington, KY

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Columbia, MO and to Lexington, KY

Here’s an overview of the most popular bus routes to Columbia, MO and to Lexington, KY. Simply click on the connection of your choice, and you will find all the details about your bus route!