Bus Milwaukee to Columbia, MO: Compare prices and save money

Compare all timetables for the bus from Milwaukee to Columbia, MO

Here is a selection of the cheapest bus trips from the schedule from Milwaukee to Columbia, MO from various bus operators like Greyhound US or FlixBus for the next days.

today

$62

tomorrow

Saturday

$68

Sunday

$70

Monday

$68

Tuesday

$70

Wednesday

$74

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 25m	6:30 AM	Milwaukee	Central Bus Station	6:55 PM	Columbia, MO	Red Thread	Economy	$62	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/4/2026 6:30:00 AM to Red Thread, Columbia, MO (USA) arriving at 6/4/2026 6:55:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 12h 25m
Greyhound US	14h 45m	7:55 PM	Milwaukee	Central Bus Station	10:40 AM	Columbia, MO	Bus Stop	Economy	$62	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/4/2026 7:55:00 PM to Bus Stop, Columbia, MO (USA) arriving at 6/5/2026 10:40:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 14h 45m
FlixBus	23h 45m	9:00 AM	Milwaukee	Central Bus Station	8:45 AM	Columbia, MO	Red Thread	Economy	$62	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 6/4/2026 9:00:00 AM to Red Thread, Columbia, MO (USA) arriving at 6/5/2026 8:45:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 23h 45m
FlixBus	23h 20m	9:00 AM	Milwaukee	Central Bus Station	8:20 AM	Columbia, MO	Bus Stop	Economy	$62	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 6/4/2026 9:00:00 AM to Bus Stop, Columbia, MO (USA) arriving at 6/5/2026 8:20:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 23h 20m
Greyhound US	15h 10m	7:55 PM	Milwaukee	Central Bus Station	11:05 AM	Columbia, MO	Red Thread	Economy	$63	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/4/2026 7:55:00 PM to Red Thread, Columbia, MO (USA) arriving at 6/5/2026 11:05:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 15h 10m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 10m	7:55 PM	Milwaukee	Central Bus Station	11:05 AM	Columbia, MO	Red Thread	Economy	$68	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/6/2026 7:55:00 PM to Red Thread, Columbia, MO (USA) arriving at 6/7/2026 11:05:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 15h 10m
Greyhound US	14h 45m	7:55 PM	Milwaukee	Central Bus Station	10:40 AM	Columbia, MO	Bus Stop	Economy	$69	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/6/2026 7:55:00 PM to Bus Stop, Columbia, MO (USA) arriving at 6/7/2026 10:40:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 14h 45m
FlixBus	20h 55m	11:50 AM	Milwaukee	Central Bus Station	8:45 AM	Columbia, MO	Red Thread	Economy	$69	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 6/6/2026 11:50:00 AM to Red Thread, Columbia, MO (USA) arriving at 6/7/2026 8:45:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 20h 55m
FlixBus	20h 30m	11:50 AM	Milwaukee	Central Bus Station	8:20 AM	Columbia, MO	Bus Stop	Economy	$69	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 6/6/2026 11:50:00 AM to Bus Stop, Columbia, MO (USA) arriving at 6/7/2026 8:20:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 20h 30m
Greyhound US	12h 25m	6:30 AM	Milwaukee	Central Bus Station	6:55 PM	Columbia, MO	Red Thread	Economy	$77	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/6/2026 6:30:00 AM to Red Thread, Columbia, MO (USA) arriving at 6/6/2026 6:55:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 12h 25m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 10m	7:55 PM	Milwaukee	Central Bus Station	11:05 AM	Columbia, MO	Red Thread	Economy	$70	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/7/2026 7:55:00 PM to Red Thread, Columbia, MO (USA) arriving at 6/8/2026 11:05:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 15h 10m
Greyhound US	14h 45m	7:55 PM	Milwaukee	Central Bus Station	10:40 AM	Columbia, MO	Bus Stop	Economy	$70	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/7/2026 7:55:00 PM to Bus Stop, Columbia, MO (USA) arriving at 6/8/2026 10:40:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 14h 45m
FlixBus	20h 55m	11:50 AM	Milwaukee	Central Bus Station	8:45 AM	Columbia, MO	Red Thread	Economy	$70	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 6/7/2026 11:50:00 AM to Red Thread, Columbia, MO (USA) arriving at 6/8/2026 8:45:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 20h 55m
FlixBus	20h 30m	11:50 AM	Milwaukee	Central Bus Station	8:20 AM	Columbia, MO	Bus Stop	Economy	$71	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 6/7/2026 11:50:00 AM to Bus Stop, Columbia, MO (USA) arriving at 6/8/2026 8:20:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 20h 30m
Greyhound US	12h 25m	6:30 AM	Milwaukee	Central Bus Station	6:55 PM	Columbia, MO	Red Thread	Economy	$74	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/7/2026 6:30:00 AM to Red Thread, Columbia, MO (USA) arriving at 6/7/2026 6:55:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 12h 25m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 10m	7:55 PM	Milwaukee	Central Bus Station	11:05 AM	Columbia, MO	Red Thread	Economy	$68	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/8/2026 7:55:00 PM to Red Thread, Columbia, MO (USA) arriving at 6/9/2026 11:05:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 15h 10m
Greyhound US	14h 45m	7:55 PM	Milwaukee	Central Bus Station	10:40 AM	Columbia, MO	Bus Stop	Economy	$69	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/8/2026 7:55:00 PM to Bus Stop, Columbia, MO (USA) arriving at 6/9/2026 10:40:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 14h 45m
FlixBus	20h 55m	11:50 AM	Milwaukee	Central Bus Station	8:45 AM	Columbia, MO	Red Thread	Economy	$69	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 6/8/2026 11:50:00 AM to Red Thread, Columbia, MO (USA) arriving at 6/9/2026 8:45:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 20h 55m
FlixBus	20h 30m	11:50 AM	Milwaukee	Central Bus Station	8:20 AM	Columbia, MO	Bus Stop	Economy	$69	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 6/8/2026 11:50:00 AM to Bus Stop, Columbia, MO (USA) arriving at 6/9/2026 8:20:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 20h 30m
Greyhound US	12h 25m	6:30 AM	Milwaukee	Central Bus Station	6:55 PM	Columbia, MO	Red Thread	Economy	$76	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/8/2026 6:30:00 AM to Red Thread, Columbia, MO (USA) arriving at 6/8/2026 6:55:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 12h 25m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 10m	7:55 PM	Milwaukee	Central Bus Station	11:05 AM	Columbia, MO	Red Thread	Economy	$70	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/9/2026 7:55:00 PM to Red Thread, Columbia, MO (USA) arriving at 6/10/2026 11:05:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 15h 10m
Greyhound US	14h 45m	7:55 PM	Milwaukee	Central Bus Station	10:40 AM	Columbia, MO	Bus Stop	Economy	$70	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/9/2026 7:55:00 PM to Bus Stop, Columbia, MO (USA) arriving at 6/10/2026 10:40:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 14h 45m
Greyhound US	12h 25m	6:30 AM	Milwaukee	Central Bus Station	6:55 PM	Columbia, MO	Red Thread	Economy	$71	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/9/2026 6:30:00 AM to Red Thread, Columbia, MO (USA) arriving at 6/9/2026 6:55:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 12h 25m
FlixBus	20h 55m	11:50 AM	Milwaukee	Central Bus Station	8:45 AM	Columbia, MO	Red Thread	Economy	$71	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 6/9/2026 11:50:00 AM to Red Thread, Columbia, MO (USA) arriving at 6/10/2026 8:45:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 20h 55m
FlixBus	20h 30m	11:50 AM	Milwaukee	Central Bus Station	8:20 AM	Columbia, MO	Bus Stop	Economy	$71	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 6/9/2026 11:50:00 AM to Bus Stop, Columbia, MO (USA) arriving at 6/10/2026 8:20:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 20h 30m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 10m	7:55 PM	Milwaukee	Central Bus Station	11:05 AM	Columbia, MO	Red Thread	Economy	$74	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/10/2026 7:55:00 PM to Red Thread, Columbia, MO (USA) arriving at 6/11/2026 11:05:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 15h 10m
Greyhound US	14h 45m	7:55 PM	Milwaukee	Central Bus Station	10:40 AM	Columbia, MO	Bus Stop	Economy	$74	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/10/2026 7:55:00 PM to Bus Stop, Columbia, MO (USA) arriving at 6/11/2026 10:40:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 14h 45m
FlixBus	23h 45m	9:00 AM	Milwaukee	Central Bus Station	8:45 AM	Columbia, MO	Red Thread	Economy	$74	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 6/10/2026 9:00:00 AM to Red Thread, Columbia, MO (USA) arriving at 6/11/2026 8:45:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 23h 45m
FlixBus	23h 20m	9:00 AM	Milwaukee	Central Bus Station	8:20 AM	Columbia, MO	Bus Stop	Economy	$74	A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 6/10/2026 9:00:00 AM to Bus Stop, Columbia, MO (USA) arriving at 6/11/2026 8:20:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 23h 20m
Greyhound US	12h 25m	6:30 AM	Milwaukee	Central Bus Station	6:55 PM	Columbia, MO	Red Thread	Economy	$79	A Bus from Greyhound US goes from Central Bus Station, Milwaukee (USA) at 6/10/2026 6:30:00 AM to Red Thread, Columbia, MO (USA) arriving at 6/10/2026 6:55:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 12h 25m

Best Price Offer: The price for the cheapest bus from Milwaukee to Columbia, MO is $62 on 6/4/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Milwaukee and Columbia, MO

See here how frequent the connections between Milwaukee and Columbia, MO are, during different times and days of the week.

Sunday is the busiest day, with more than 10 daily buses from Milwaukee to Columbia, MO. Monday has instead the fewest connections, with only 5 daily coaches between Milwaukee and Columbia, MO.

The busiest time of the day is the Morning, with 27 buses from Milwaukee to Columbia, MO, while Evening sees the fewest connections between Milwaukee and Columbia, MO, with 18 offers.

Facts about the bus from Milwaukee to Columbia, MO

Compare all providers like Greyhound US and FlixBus that travel 7 times every day by bus from Milwaukee to Columbia, MO in one click! Book your bus ticket from Milwaukee to Columbia, MO starting from $62!

Cheapest Bus	$62
Fastest Bus	12h 25m
Earliest Bus	6:30 AM
Latest Bus	7:55 PM
Daily Bus Routes	7 Ø
Distance	363.8 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Milwaukee to Columbia, MO

Every day, 7 buses from 2 bus companies leave Milwaukee for Columbia, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/04/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/31

Monday 06/01

Tuesday 06/02

Wednesday 06/03

Thursday 06/04

$62

Friday 06/05

Saturday 06/06

$72

Sunday 06/07

$70

Monday 06/08

$68

Tuesday 06/09

$70

Wednesday 06/10

$74

Thursday 06/11

$75

Friday 06/12

$84

Saturday 06/13

$79

Sunday 06/14

$77

Monday 06/15

$67

Tuesday 06/16

Wednesday 06/17

$74

Thursday 06/18

$75

Friday 06/19

$72

Saturday 06/20

$70

Sunday 06/21

$67

Monday 06/22

$70

Tuesday 06/23

$73

Wednesday 06/24

$80

Thursday 06/25

$75

Friday 06/26

$84

Saturday 06/27

The cheapest time to travel from Milwaukee to Columbia, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Milwaukee to Columbia, MO, for the next 30 days.

With a price starting from $62, Thursday is the cheapest day for a bus from Milwaukee to Columbia, MO. Wednesday instead is the most expensive day with prices starting from $74.

Morning is the cheapest day time for bus tickets from Milwaukee to Columbia, MO, with $62. Evening is the most expensive time of the day with prices starting from $62.

How to save money travelling from Milwaukee to Columbia, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milwaukee to Columbia, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milwaukee to Columbia, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milwaukee to Columbia, MO are also emptier.

All bus stations and stops in Milwaukee and Columbia, MO

In the map below, you can see where to find all bus stations in Milwaukee and Columbia, MO.

Intermodal Station

W. St Paul's Ave 433

Central Bus Station

4960 S. 13th St. Park

Badger

N James Lovell St 635

Downtown Bus Station

Bus Stop

N 10th St 198

Red Thread

Highway 40 W 6401

University

Fellows Pl 1301-1349

Service and Comfort on the bus from Milwaukee to Columbia, MO

Want to know which seat classes are available on the buses from Milwaukee to Columbia, MO? Or which bus companies serve the route Milwaukee to Columbia, MO? Below you will find answers to your questions.

FAQs about the Milwaukee to Columbia, MO bus

How much does a Milwaukee Columbia, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $62 and takes 23h 45m to reach Columbia, MO. Compare offers to save money!

How much could I save by comparing buses from Milwaukee to Columbia, MO?

This route is offered by 2 companies with a range of ticket prices between $62 and $81. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Columbia, MO.

On average, how many connections are available from Milwaukee to Columbia, MO each day?

Every day, the Milwaukee to Columbia, MO bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milwaukee to Columbia, MO take?

The fastest bus from Milwaukee to Columbia, MO is offered by Greyhound US and takes 12h 25m. Bus tickets for this connection cost $62. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milwaukee to Columbia, MO?

The earliest bus arriving in Columbia, MO from Milwaukee starts at 6:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milwaukee to Columbia, MO?

The latest bus trip departing from Milwaukee for Columbia, MO starts at 7:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milwaukee Columbia, MO route?

When traveling by bus from Milwaukee to Columbia, MO, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milwaukee and Columbia, MO?

You can check all the direct connections between Milwaukee and Columbia, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Milwaukee to Columbia, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milwaukee Columbia, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milwaukee Columbia, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milwaukee to Columbia, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Milwaukee to Columbia, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Milwaukee and Columbia, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milwaukee to Columbia, MO?

Prices and availability for 7 trips between Milwaukee and Columbia, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milwaukee to Columbia, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milwaukee and to Columbia, MO

Here’s an overview of the most popular bus routes to Milwaukee and to Columbia, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!