Bus from Gainesville, FL to Greenville, SC from $54

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Compare all timetables for the bus from Gainesville, FL to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Gainesville, FL to Greenville, SC from various bus operators like FlixBus or Greyhound US for the next days.
today
from $68
tomorrow
Thursday
Friday
from $62
Saturday
Sunday
Monday
from $54

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    9h 30m
    0
    1:10 AM
    Gainesville, FL
    Rosa Parks Transfer station
    10:40 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $68
  • FlixBus
    10h 25m
    0
    11:30 AM
    Gainesville, FL
    Rosa Parks Transfer station
    9:55 PM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $68
  • FlixBus
    14h 40m
    0
    8:00 PM
    Gainesville, FL
    Rosa Parks Transfer station
    10:40 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $68
  • Greyhound US
    12h 25m
    0
    8:00 AM
    Gainesville, FL
    North Walmart Supercenter Bus Stop
    8:25 PM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $68
  • Greyhound US
    9h 25m
    0
    12:30 PM
    Gainesville, FL
    North Walmart Supercenter Bus Stop
    9:55 PM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $68

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    10h 25m
    0
    11:30 AM
    Gainesville, FL
    Rosa Parks Transfer station
    9:55 PM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $62
  • Greyhound US
    9h 25m
    0
    12:30 PM
    Gainesville, FL
    North Walmart Supercenter Bus Stop
    9:55 PM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $63
  • FlixBus
    9h 30m
    0
    1:10 AM
    Gainesville, FL
    Rosa Parks Transfer station
    10:40 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $64
  • FlixBus
    13h 55m
    0
    5:40 PM
    Gainesville, FL
    Rosa Parks Transfer station
    7:35 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $64
  • Greyhound US
    17h 0m
    0
    2:35 PM
    Gainesville, FL
    North Walmart Supercenter Bus Stop
    7:35 AM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $64

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    10h 25m
    0
    11:30 AM
    Gainesville, FL
    Rosa Parks Transfer station
    9:55 PM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $54
  • FlixBus
    9h 30m
    0
    1:10 AM
    Gainesville, FL
    Rosa Parks Transfer station
    10:40 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $55
  • FlixBus
    14h 40m
    0
    8:00 PM
    Gainesville, FL
    Rosa Parks Transfer station
    10:40 AM
    Greenville, SC
    Woodruff Rd
    0
    FlixBus
    Economy
    $55
  • Greyhound US
    12h 25m
    0
    8:00 AM
    Gainesville, FL
    North Walmart Supercenter Bus Stop
    8:25 PM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $55
  • Greyhound US
    9h 25m
    0
    12:30 PM
    Gainesville, FL
    North Walmart Supercenter Bus Stop
    9:55 PM
    Greenville, SC
    Woodruff Rd
    0
    Greyhound US
    Economy
    $55

Frequency of bus connections between Gainesville, FL and Greenville, SC

See here how frequent the connections between Gainesville, FL and Greenville, SC are, during different times and days of the week.
Monday is the busiest day, with more than 14 daily buses from Gainesville, FL to Greenville, SC. Tuesday has instead the fewest connections, with only 7 daily coaches between Gainesville, FL and Greenville, SC.
The busiest time of the day is the Afternoon, with 12 buses from Gainesville, FL to Greenville, SC, while Evening sees the fewest connections between Gainesville, FL and Greenville, SC, with 4 offers.

Facts about the bus from Gainesville, FL to Greenville, SC

Compare all providers like FlixBus and Greyhound US that travel 9 times every day by bus from Gainesville, FL to Greenville, SC in one click! Book your bus ticket from Gainesville, FL to Greenville, SC starting from $54!

Cheapest Bus $54
Fastest Bus 9h 25m
Earliest Bus 1:10 AM
Latest Bus 8:00 PM
Daily Bus Routes 9 Ø
Distance 359.9 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Gainesville, FL to Greenville, SC

Every day, 9 buses from 2 bus companies leave Gainesville, FL for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/13/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/11
Monday 05/12
Tuesday 05/13
$68
Wednesday 05/14
Thursday 05/15
Friday 05/16
$62
Saturday 05/17
Sunday 05/18
Monday 05/19
$54
Tuesday 05/20
$84
Wednesday 05/21
Thursday 05/22
Friday 05/23
Saturday 05/24
Sunday 05/25
$68
Monday 05/26
Tuesday 05/27
Wednesday 05/28
Thursday 05/29
Friday 05/30
Saturday 05/31
Sunday 06/01
Monday 06/02
Tuesday 06/03
Wednesday 06/04
Thursday 06/05
Friday 06/06
Saturday 06/07

The cheapest time to travel from Gainesville, FL to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Gainesville, FL to Greenville, SC, for the next 30 days.
With a price starting from $54, Monday is the cheapest day for a bus from Gainesville, FL to Greenville, SC. Tuesday instead is the most expensive day with prices starting from $68.
Morning is the cheapest day time for bus tickets from Gainesville, FL to Greenville, SC, with $54. Afternoon is the most expensive time of the day with prices starting from $55.

How to save money travelling from Gainesville, FL to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Gainesville, FL to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Gainesville, FL to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Gainesville, FL to Greenville, SC are also emptier.

All bus stations and stops in Gainesville, FL and Greenville, SC

In the map below, you can see where to find all bus stations in Gainesville, FL and Greenville, SC.

Service and Comfort on the bus from Gainesville, FL to Greenville, SC

Want to know which seat classes are available on the buses from Gainesville, FL to Greenville, SC? Or which bus companies serve the route Gainesville, FL to Greenville, SC? Below you will find answers to your questions.

FAQs about the Gainesville, FL to Greenville, SC bus

How much does a Gainesville, FL Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $54 and takes 10h 25m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Gainesville, FL to Greenville, SC?

This route is offered by 2 companies with a range of ticket prices between $54 and $84. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Gainesville, FL to Greenville, SC each day?

Every day, the Gainesville, FL to Greenville, SC bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Gainesville, FL to Greenville, SC take?

The fastest bus from Gainesville, FL to Greenville, SC is offered by Greyhound US and takes 9h 25m. Bus tickets for this connection cost $68. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Gainesville, FL to Greenville, SC?

The earliest bus arriving in Greenville, SC from Gainesville, FL starts at 1:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Gainesville, FL to Greenville, SC?

The latest bus trip departing from Gainesville, FL for Greenville, SC starts at 8:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Gainesville, FL Greenville, SC route?

When traveling by bus from Gainesville, FL to Greenville, SC, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Gainesville, FL and Greenville, SC?

You can check all the direct connections between Gainesville, FL and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Gainesville, FL to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Gainesville, FL Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Gainesville, FL Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Gainesville, FL to Greenville, SC on your planned travel date.

Available seat classes which are offered on the bus route Gainesville, FL to Greenville, SC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Gainesville, FL and to Greenville, SC

Here’s an overview of the most popular bus routes to Gainesville, FL and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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