Bus from Tampa to Greenville, SC from $85

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Compare all timetables for the bus from Tampa to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Tampa to Greenville, SC from various bus operators like FlixBus or Greyhound US for the next days.

today
$104
tomorrow
Tuesday
$95
Wednesday
$87
Thursday
Friday
$124
Saturday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 50m 10:35 PM Tampa Marion Street 7:25 PM Greenville, SC Woodruff Rd  Economy $104
FlixBus 21h 35m 9:50 PM Tampa USF 7:25 PM Greenville, SC Woodruff Rd  Economy $104
FlixBus 13h 35m 5:25 PM Tampa Marion Street 7:00 AM Greenville, SC Woodruff Rd  Economy $105
FlixBus 13h 5m 5:55 PM Tampa USF 7:00 AM Greenville, SC Woodruff Rd  Economy $106
FlixBus 15h 35m 6:20 AM Tampa Marion Street 9:55 PM Greenville, SC Woodruff Rd  Economy $108
  • Did you know that if you travel from Tampa to Greenville, SC via Orlando, FL, you can save more than $16? You can find the corresponding connections below.
    • FlixBus
      13h 5m
      0
      5:55 PM
      Tampa
      USF
      7:45 PM
      Orlando, FL
      Bus Station
      0
      FlixBus
      Economy
      $15
      • Waiting Time 1h 0m
    • FlixBus
      10h 15m
      0
      8:45 PM
      Orlando, FL
      Bus Station
      7:00 AM
      Greenville, SC
      Woodruff Rd
      0
      FlixBus
      Economy
      $73
    Travel time is the same as the direct connection, but you will save $16

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 19h 50m 11:10 AM Tampa Marion Street 7:00 AM Greenville, SC Woodruff Rd  Economy $95
FlixBus 17h 15m 5:25 PM Tampa Marion Street 10:40 AM Greenville, SC Woodruff Rd  Economy $96
FlixBus 15h 35m 6:20 AM Tampa Marion Street 9:55 PM Greenville, SC Woodruff Rd  Economy $97
FlixBus 23h 20m 10:35 PM Tampa Marion Street 9:55 PM Greenville, SC Woodruff Rd  Economy $97

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 35m 5:25 PM Tampa Marion Street 7:00 AM Greenville, SC Woodruff Rd  Economy $87
FlixBus 15h 35m 6:20 AM Tampa Marion Street 9:55 PM Greenville, SC Woodruff Rd  Economy $88
FlixBus 23h 20m 10:35 PM Tampa Marion Street 9:55 PM Greenville, SC Woodruff Rd  Economy $88
FlixBus 24h 5m 9:50 PM Tampa USF 9:55 PM Greenville, SC Woodruff Rd  Economy $88
FlixBus 13h 5m 5:55 PM Tampa USF 7:00 AM Greenville, SC Woodruff Rd  Economy $89

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 50m 10:35 PM Tampa Marion Street 7:25 PM Greenville, SC Woodruff Rd  Economy $124
FlixBus 21h 15m 10:10 PM Tampa USF 7:25 PM Greenville, SC Woodruff Rd  Economy $124
Greyhound US 19h 50m 11:10 AM Tampa Marion Street 7:00 AM Greenville, SC Woodruff Rd  Economy $126
FlixBus 15h 35m 6:20 AM Tampa Marion Street 9:55 PM Greenville, SC Woodruff Rd  Economy $127
  • Did you know that if you travel from Tampa to Greenville, SC via Orlando, FL, you can save more than $37? You can find the corresponding connections below.
    • FlixBus
      15h 35m
      0
      6:20 AM
      Tampa
      Marion Street
      8:20 AM
      Orlando, FL
      Bus Station
      0
      FlixBus
      Economy
      $10
      • Waiting Time 0h 40m
    • FlixBus
      12h 55m
      0
      9:00 AM
      Orlando, FL
      Bus Station
      9:55 PM
      Greenville, SC
      Woodruff Rd
      0
      FlixBus
      Economy
      $77
    Travel time is the same as the direct connection, but you will save $37

Best Price Offer: The price for the cheapest bus from Tampa to Greenville, SC is $85 on 4/4/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Tampa and Greenville, SC

See here how frequent the connections between Tampa and Greenville, SC are, during different times and days of the week.
Friday is the busiest day, with more than 12 daily buses from Tampa to Greenville, SC. Sunday has instead the fewest connections, with only 5 daily coaches between Tampa and Greenville, SC.
The busiest time of the day is the Afternoon, with 12 buses from Tampa to Greenville, SC, while Morning sees the fewest connections between Tampa and Greenville, SC, with 10 offers.

Facts about the bus from Tampa to Greenville, SC

Compare all providers like FlixBus and Greyhound US that travel 8 times every day by bus from Tampa to Greenville, SC in one click! Book your bus ticket from Tampa to Greenville, SC starting from $85!

Cheapest Bus $85
Fastest Bus 13h 5m
Earliest Bus 6:20 AM
Latest Bus 10:35 PM
Daily Bus Routes 8 Ø
Distance 476.7 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Tampa to Greenville, SC

Every day, 8 buses from 2 bus companies leave Tampa for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/22/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/22
$104
Monday 03/23
Tuesday 03/24
$95
Wednesday 03/25
$87
Thursday 03/26
Friday 03/27
$120
Saturday 03/28
Sunday 03/29
$116
Monday 03/30
$96
Tuesday 03/31
Wednesday 04/01
Thursday 04/02
Friday 04/03
Saturday 04/04
$85
Sunday 04/05
$92
Monday 04/06
$86
Tuesday 04/07
$92
Wednesday 04/08
$86
Thursday 04/09
Friday 04/10
$91
Saturday 04/11
$96
Sunday 04/12
$99
Monday 04/13
$87
Tuesday 04/14
$116
Wednesday 04/15
$94
Thursday 04/16
$116
Friday 04/17
$91
Saturday 04/18

The cheapest time to travel from Tampa to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Tampa to Greenville, SC, for the next 30 days.
With a price starting from $86, Wednesday is the cheapest day for a bus from Tampa to Greenville, SC. Sunday instead is the most expensive day with prices starting from $92.
Afternoon is the cheapest day time for bus tickets from Tampa to Greenville, SC, with $87. Morning is the most expensive time of the day with prices starting from $88.

How to save money travelling from Tampa to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tampa to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tampa to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tampa to Greenville, SC are also emptier.

All bus stations and stops in Tampa and Greenville, SC

In the map below, you can see where to find all bus stations in Tampa and Greenville, SC.

Service and Comfort on the bus from Tampa to Greenville, SC

Want to know which seat classes are available on the buses from Tampa to Greenville, SC? Or which bus companies serve the route Tampa to Greenville, SC? Below you will find answers to your questions.

FAQs about the Tampa to Greenville, SC bus

How much does a Tampa Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $85 and takes 13h 35m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Tampa to Greenville, SC?

This route is offered by 2 companies with a range of ticket prices between $85 and $129. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Tampa to Greenville, SC each day?

Every day, the Tampa to Greenville, SC bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tampa to Greenville, SC take?

The fastest bus from Tampa to Greenville, SC is offered by FlixBus and takes 13h 5m. Bus tickets for this connection cost $106. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tampa to Greenville, SC?

The earliest bus arriving in Greenville, SC from Tampa starts at 6:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tampa to Greenville, SC?

The latest bus trip departing from Tampa for Greenville, SC starts at 10:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tampa Greenville, SC route?

When traveling by bus from Tampa to Greenville, SC, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tampa and Greenville, SC?

You can check all the direct connections between Tampa and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Tampa to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tampa Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tampa Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tampa to Greenville, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Tampa to Greenville, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 8 daily trips between Tampa and Greenville, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Tampa to Greenville, SC?

Prices and availability for 8 trips between Tampa and Greenville, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Tampa to Greenville, SC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tampa and to Greenville, SC

Here’s an overview of the most popular bus routes to Tampa and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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