Compare all timetables for the bus from Syracuse, NY to Greenville, SC
Here is a selection of the cheapest bus trips from the schedule from Syracuse, NY to Greenville, SC from various bus operators like FlixBus or Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 22h 40m | 9:00 PM | Syracuse, NY | Regional Transit Center | 7:40 PM | Greenville, SC | Woodruff Rd | Economy | $119 |
A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 12/6/2025 9:00:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 12/7/2025 7:40:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 22h 40m
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| FlixBus | 21h 50m | 10:45 AM | Syracuse, NY | Regional Transit Center | 8:35 AM | Greenville, SC | Woodruff Rd | Economy | $122 |
A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 12/6/2025 10:45:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 12/7/2025 8:35:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 21h 50m
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| FlixBus | 22h 15m | 3:00 PM | Syracuse, NY | Regional Transit Center | 1:15 PM | Greenville, SC | Woodruff Rd | Economy | $160 |
A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 12/6/2025 3:00:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 12/7/2025 1:15:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 22h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 27h 20m | 7:30 AM | Syracuse, NY | Regional Transit Center | 10:50 AM | Greenville, SC | Woodruff Rd | Economy | $106 |
A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 12/8/2025 7:30:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 12/9/2025 10:50:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 27h 20m
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| FlixBus | 22h 15m | 3:00 PM | Syracuse, NY | Regional Transit Center | 1:15 PM | Greenville, SC | Woodruff Rd | Economy | $107 |
A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 12/8/2025 3:00:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 12/9/2025 1:15:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 22h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 23h 10m | 9:25 AM | Syracuse, NY | Regional Transit Center | 8:35 AM | Greenville, SC | Woodruff Rd | Economy | $111 |
A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 12/10/2025 9:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 12/11/2025 8:35:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 23h 10m
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| FlixBus | 25h 10m | 12:05 PM | Syracuse, NY | Regional Transit Center | 1:15 PM | Greenville, SC | Woodruff Rd | Economy | $114 |
A Bus from FlixBus goes from Regional Transit Center, Syracuse, NY (USA) at 12/10/2025 12:05:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 12/11/2025 1:15:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 25h 10m
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| Greyhound US | 35h 35m | 9:00 PM | Syracuse, NY | Regional Transit Center | 8:35 AM | Greenville, SC | Woodruff Rd | Economy | $122 |
A Bus from Greyhound US goes from Regional Transit Center, Syracuse, NY (USA) at 12/10/2025 9:00:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 12/12/2025 8:35:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 35h 35m
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Best Price Offer: The price for the cheapest bus from Syracuse, NY to Greenville, SC is $106 on 12/8/2025. Flexible travelers save on ticket prices.
Frequency of bus connections between Syracuse, NY and Greenville, SC
Wednesday
is the busiest day, with more than 3 daily buses from Syracuse, NY to Greenville, SC. Monday has instead the fewest connections, with only 2 daily coaches between Syracuse, NY and Greenville, SC.
The busiest time of the day is the Morning, with 3 buses from Syracuse, NY to Greenville, SC, while Evening sees the fewest connections between Syracuse, NY and Greenville, SC, with 2 offers.
Facts about the bus from Syracuse, NY to Greenville, SC
Compare all providers like FlixBus and Greyhound US that travel 2 times every day by bus from Syracuse, NY to Greenville, SC in one click! Book your bus ticket from Syracuse, NY to Greenville, SC starting from $106!
| Cheapest Bus | $106 |
| Fastest Bus | 21h 50m |
| Earliest Bus | 10:45 AM |
| Latest Bus | 9:00 PM |
| Daily Bus Routes | 2 Ø |
| Distance | 658.2 miles |
| Bus Companies | FlixBus and Greyhound US |
Cheapest bus connections from Syracuse, NY to Greenville, SC
Every day, 2 buses from 2 bus companies leave Syracuse, NY for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
11/30
Monday
12/01
Tuesday
12/02
Wednesday
12/03
Thursday
12/04
Friday
12/05
Saturday
12/06
$119
Sunday
12/07
Monday
12/08
$106
Tuesday
12/09
Wednesday
12/10
$111
Thursday
12/11
$108
Friday
12/12
Saturday
12/13
Sunday
12/14
Monday
12/15
Tuesday
12/16
Wednesday
12/17
Thursday
12/18
Friday
12/19
Saturday
12/20
Sunday
12/21
Monday
12/22
Tuesday
12/23
Wednesday
12/24
Thursday
12/25
Friday
12/26
Saturday
12/27
The cheapest time to travel from Syracuse, NY to Greenville, SC
With a price starting from $106, Monday is the cheapest day for a bus from Syracuse, NY to Greenville, SC. Saturday instead is the most expensive day with prices starting from $119.
Morning
is the cheapest day time for bus tickets from Syracuse, NY to Greenville, SC, with $106. Evening is the most expensive time of the day with prices starting from $119.
How to save money travelling from Syracuse, NY to Greenville, SC
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Syracuse, NY to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Syracuse, NY to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Syracuse, NY to Greenville, SC are also emptier.All bus stations and stops in Syracuse, NY and Greenville, SC
In the map below, you can see where to find all bus stations in Syracuse, NY and Greenville, SC.
Service and Comfort on the bus from Syracuse, NY to Greenville, SC
Want to know which seat classes are available on the buses from Syracuse, NY to Greenville, SC? Or which bus companies serve the route Syracuse, NY to Greenville, SC? Below you will find answers to your questions.
FAQs about the Syracuse, NY to Greenville, SC bus
How much does a Syracuse, NY Greenville, SC bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $106 and takes 27h 20m to reach Greenville, SC. Compare offers to save money!
How much could I save by comparing buses from Syracuse, NY to Greenville, SC?
This route is offered by 2 companies with a range of ticket prices between $106 and $160. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.
On average, how many connections are available from Syracuse, NY to Greenville, SC each day?
Every day, the Syracuse, NY to Greenville, SC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Syracuse, NY to Greenville, SC take?
The fastest bus from Syracuse, NY to Greenville, SC is offered by FlixBus and takes 21h 50m. Bus tickets for this connection cost $122. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Syracuse, NY to Greenville, SC?
The earliest bus arriving in Greenville, SC from Syracuse, NY starts at 10:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Syracuse, NY to Greenville, SC?
The latest bus trip departing from Syracuse, NY for Greenville, SC starts at 9:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Syracuse, NY Greenville, SC route?
When traveling by bus from Syracuse, NY to Greenville, SC, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Syracuse, NY and Greenville, SC?
You can check all the direct connections between Syracuse, NY and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.
What can I take with me on the Syracuse, NY to Greenville, SC bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Syracuse, NY Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Syracuse, NY Greenville, SC bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Syracuse, NY to Greenville, SC on your planned travel date.
Available seat classes which are offered on the bus route Syracuse, NY to Greenville, SC
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Syracuse, NY and to Greenville, SC
Here’s an overview of the most popular bus routes to Syracuse, NY and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Syracuse, NY
- Buses Atlanta, GA to Syracuse, NY
- From Baltimore, MD to Syracuse, NY bus
- Bus from Buffalo, NY to Syracuse, NY
- Bus to Syracuse, NY from Cambridge, MA
- From Cleveland to Syracuse, NY bus
- Columbus, OH to Syracuse, NY bus
- Buses Dallas to Syracuse, NY
- Easton, PA to Syracuse, NY bus
- Bus Elkton, MD to Syracuse, NY
- Buses Greenville, NC - Syracuse, NY
- Bus from Ithaca, NY to Syracuse, NY
- Bus to Syracuse, NY from Jacksonville, FL
- Bus to Syracuse, NY from Jacksonville, NC
- Buses from Newburgh, NY to Syracuse, NY
- Buses Pittsburgh - Syracuse, NY
- Bus from Queens Village, NY to Syracuse, NY
- Buses from Rochester, NY to Syracuse, NY
- Bus to Syracuse, NY from Toronto, ON
- Bus Utica, NY - Syracuse, NY
- Youngstown, OH to Syracuse, NY bus
- Bus Routes to Greenville, SC
- Buses to Greenville, SC from Baltimore, MD
- Binghamton, NY to Greenville, SC bus
- Birmingham, AL to Greenville, SC bus
- Bus Chicago - Greenville, SC
- Buses Detroit - Greenville, SC
- From Durham, NC to Greenville, SC bus
- Buses to Greenville, SC from Evansville, IN
- From Fort Myers, FL to Greenville, SC bus
- Gainesville, FL to Greenville, SC bus
- Buses to Greenville, SC from Greenville, NC
- Bus Miami to Greenville, SC
- Buses Myrtle Beach, SC - Greenville, SC
- Bus to Greenville, SC from New York
- Bus Newark - Greenville, SC
- Buses from Orlando, FL to Greenville, SC
- Bus San Antonio, TX - Greenville, SC
- Silver Spring, MD to Greenville, SC bus
- South Bend, IN to Greenville, SC bus
- Buses Tampa to Greenville, SC
- Buses Washington, DC - Greenville, SC
Popular Airport Shuttles to Syracuse, NY and to Greenville, SC
