Compare all timetables for the bus from Knoxville, TN to Greenville, SC
Here is a selection of the cheapest bus trips from the schedule from Knoxville, TN to Greenville, SC from various bus operators like Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 12h 0m | 7:05 PM | Knoxville, TN | Greyhound Bus Station | 7:05 AM | Greenville, SC | Woodruff Rd | Economy | $112 |
A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/5/2025 7:05:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 12/6/2025 7:05:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 0m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 12h 0m | 7:05 PM | Knoxville, TN | Greyhound Bus Station | 7:05 AM | Greenville, SC | Woodruff Rd | Economy | $112 |
A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/6/2025 7:05:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 12/7/2025 7:05:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 0m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 12h 0m | 7:05 PM | Knoxville, TN | Greyhound Bus Station | 7:05 AM | Greenville, SC | Woodruff Rd | Economy | $122 |
A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/8/2025 7:05:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 12/9/2025 7:05:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 12h 0m
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Best Price Offer: The price for the cheapest bus from Knoxville, TN to Greenville, SC is $112 on 12/5/2025. Flexible travelers save on ticket prices.
Facts about the bus from Knoxville, TN to Greenville, SC
Compare all providers like Greyhound US that travel 1 times every day by bus from Knoxville, TN to Greenville, SC in one click! Book your bus ticket from Knoxville, TN to Greenville, SC starting from $112!
| Cheapest Bus | $112 |
| Fastest Bus | 12h 0m |
| Earliest Bus | 7:05 PM |
| Latest Bus | 7:05 PM |
| Daily Bus Routes | 1 Ø |
| Distance | 115.0 miles |
| Bus Companies | Greyhound US |
Cheapest bus connections from Knoxville, TN to Greenville, SC
Every day, 1 buses from 1 bus companies leave Knoxville, TN for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
11/30
Monday
12/01
Tuesday
12/02
Wednesday
12/03
Thursday
12/04
Friday
12/05
$112
Saturday
12/06
$112
Sunday
12/07
Monday
12/08
$122
Tuesday
12/09
Wednesday
12/10
Thursday
12/11
Friday
12/12
Saturday
12/13
Sunday
12/14
Monday
12/15
Tuesday
12/16
Wednesday
12/17
Thursday
12/18
Friday
12/19
Saturday
12/20
Sunday
12/21
Monday
12/22
Tuesday
12/23
Wednesday
12/24
Thursday
12/25
Friday
12/26
Saturday
12/27
How to save money travelling from Knoxville, TN to Greenville, SC
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Knoxville, TN to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Knoxville, TN to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Knoxville, TN to Greenville, SC are also emptier.All bus stations and stops in Knoxville, TN and Greenville, SC
In the map below, you can see where to find all bus stations in Knoxville, TN and Greenville, SC.
Service and Comfort on the bus from Knoxville, TN to Greenville, SC
Want to know which seat classes are available on the buses from Knoxville, TN to Greenville, SC? Or which bus companies serve the route Knoxville, TN to Greenville, SC? Below you will find answers to your questions.
FAQs about the Knoxville, TN to Greenville, SC bus
How much does a Knoxville, TN Greenville, SC bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $112 and takes 12h 0m to reach Greenville, SC. Compare offers to save money!
How much could I save by comparing buses from Knoxville, TN to Greenville, SC?
This route is offered by 1 companies with a range of ticket prices between $112 and $122. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.
On average, how many connections are available from Knoxville, TN to Greenville, SC each day?
Every day, the Knoxville, TN to Greenville, SC bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Knoxville, TN to Greenville, SC take?
The fastest bus from Knoxville, TN to Greenville, SC is offered by Greyhound US and takes 12h 0m. Bus tickets for this connection cost $112. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Knoxville, TN to Greenville, SC?
The earliest bus arriving in Greenville, SC from Knoxville, TN starts at 7:05 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Knoxville, TN to Greenville, SC?
The latest bus trip departing from Knoxville, TN for Greenville, SC starts at 7:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Knoxville, TN Greenville, SC route?
When traveling by bus from Knoxville, TN to Greenville, SC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Knoxville, TN and Greenville, SC?
You can check all the direct connections between Knoxville, TN and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.
What can I take with me on the Knoxville, TN to Greenville, SC bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Knoxville, TN Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Knoxville, TN Greenville, SC bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Knoxville, TN to Greenville, SC on your planned travel date.
Available seat classes which are offered on the bus route Knoxville, TN to Greenville, SC
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Knoxville, TN and to Greenville, SC
Here’s an overview of the most popular bus routes to Knoxville, TN and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Knoxville, TN
- Buses Baton Rouge to Knoxville, TN
- Bus to Knoxville, TN from Carbondale, IL
- Bus Chicago - Knoxville, TN
- Bus Cincinnati to Knoxville, TN
- Bus to Knoxville, TN from Detroit
- Buses to Knoxville, TN from Fort Lauderdale, FL
- Bus Fort Pierce, FL - Knoxville, TN
- Buses Greensboro, NC to Knoxville, TN
- From Indianapolis to Knoxville, TN bus
- Bus to Knoxville, TN from Lexington, KY
- Buses Louisville, KY to Knoxville, TN
- Buses from Macon, GA to Knoxville, TN
- Buses Mobile, AL to Knoxville, TN
- Bus Newark to Knoxville, TN
- Buses from Orlando, FL to Knoxville, TN
- Bus Paducah, KY - Knoxville, TN
- Bus Tampa to Knoxville, TN
- From Tifton, GA to Knoxville, TN bus
- Buses to Knoxville, TN from Toronto, ON
- Buses from Washington, DC to Knoxville, TN
- Bus Routes to Greenville, SC
- Bus Atlanta, GA - Greenville, SC
- Augusta, GA to Greenville, SC bus
- Baltimore, MD to Greenville, SC bus
- Bus to Greenville, SC from Binghamton, NY
- Buses to Greenville, SC from Charlotte
- Bus Chicago to Greenville, SC
- Bus to Greenville, SC from Cincinnati
- Bus from College Park, MD to Greenville, SC
- Detroit to Greenville, SC bus
- Buses from Durham, NC to Greenville, SC
- From Evansville, IN to Greenville, SC bus
- From Fort Myers, FL to Greenville, SC bus
- Buses to Greenville, SC from Jacksonville, FL
- Bus from Lexington, KY to Greenville, SC
- From Macon, GA to Greenville, SC bus
- Buses Newark to Greenville, SC
- Buses from Philadelphia to Greenville, SC
- Bus from Syracuse, NY to Greenville, SC
- Bus from Warner Robins, GA to Greenville, SC
- Bus Winston-Salem, NC - Greenville, SC
Popular Airport Shuttles to Knoxville, TN and to Greenville, SC
