Compare all timetables for the bus from Louisville, KY to Knoxville, TN
Cheapest bus trips tomorrow
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Greyhound US15h 50m06:00 AMLouisville, KYGreyhound Bus Station9:50 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/9/2025 6:00:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 7/9/2025 9:50:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 15h 50m
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Greyhound US8h 20m02:20 PMLouisville, KYGreyhound Bus Station10:40 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/9/2025 2:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 7/9/2025 10:40:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 8h 20m
Cheapest bus trips Friday
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Greyhound US8h 20m02:20 PMLouisville, KYGreyhound Bus Station10:40 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/11/2025 2:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 7/11/2025 10:40:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 8h 20m
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Greyhound US15h 50m06:00 AMLouisville, KYGreyhound Bus Station9:50 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/11/2025 6:00:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 7/11/2025 9:50:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 15h 50m
Cheapest bus trips Saturday
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FlixBus13h 40m08:10 AMLouisville, KYGreyhound Bus Station9:50 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 7/12/2025 8:10:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 7/12/2025 9:50:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 13h 40m
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Greyhound US8h 20m02:20 PMLouisville, KYGreyhound Bus Station10:40 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/12/2025 2:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 7/12/2025 10:40:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 8h 20m
Cheapest bus trips Sunday
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Greyhound US8h 20m02:20 PMLouisville, KYGreyhound Bus Station10:40 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 7/13/2025 2:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 7/13/2025 10:40:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 8h 20m
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FlixBus13h 40m08:10 AMLouisville, KYGreyhound Bus Station9:50 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 7/13/2025 8:10:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 7/13/2025 9:50:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 13h 40m
Frequency of bus connections between Louisville, KY and Knoxville, TN
Facts about the bus from Louisville, KY to Knoxville, TN
Compare all providers like Greyhound US and FlixBus that travel 2 times every day by bus from Louisville, KY to Knoxville, TN in one click! Book your bus ticket from Louisville, KY to Knoxville, TN starting from $52!
Cheapest Bus | $52 |
Fastest Bus | 8h 20m |
Earliest Bus | 6:00 AM |
Latest Bus | 2:20 PM |
Daily Bus Routes | 2 Ø |
Distance | 188.3 miles |
Bus Companies | Greyhound US and FlixBus |
Cheapest bus connections from Louisville, KY to Knoxville, TN
Every day, 2 buses from 2 bus companies leave Louisville, KY for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/08/2025 and for the following days.
The cheapest time to travel from Louisville, KY to Knoxville, TN
How to save money travelling from Louisville, KY to Knoxville, TN
Book the ticket from Louisville, KY to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Louisville, KY to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Louisville, KY to Knoxville, TN are also emptier.All bus stations and stops in Louisville, KY and Knoxville, TN
In the map below, you can see where to find all bus stations in Louisville, KY and Knoxville, TN.
Service and Comfort on the bus from Louisville, KY to Knoxville, TN
FAQs about the Louisville, KY to Knoxville, TN bus
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Available seat classes which are offered on the bus route Louisville, KY to Knoxville, TN
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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