Compare all timetables for the bus from Louisville, KY to Knoxville, TN
Here is a selection of the cheapest bus trips from the schedule from Louisville, KY to Knoxville, TN from various bus operators like Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 16h 5m | 2:50 AM | Louisville, KY | Greyhound Bus Station | 6:55 PM | Knoxville, TN | Greyhound Bus Station | Economy | $66 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 12/16/2025 2:50:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/16/2025 6:55:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 16h 5m
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| Greyhound US | 14h 35m | 7:15 AM | Louisville, KY | Greyhound Bus Station | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $67 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 12/16/2025 7:15:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/16/2025 9:50:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 14h 35m
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| Greyhound US | 8h 20m | 2:20 PM | Louisville, KY | Greyhound Bus Station | 10:40 PM | Knoxville, TN | Greyhound Bus Station | Economy | $67 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 12/16/2025 2:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/16/2025 10:40:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 8h 20m
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Best Price Offer: The price for the cheapest bus from Louisville, KY to Knoxville, TN is $66 on 12/16/2025. Flexible travelers save on ticket prices.
Facts about the bus from Louisville, KY to Knoxville, TN
Compare all providers like Greyhound US that travel 3 times every day by bus from Louisville, KY to Knoxville, TN in one click! Book your bus ticket from Louisville, KY to Knoxville, TN starting from $66!
| Cheapest Bus | $66 |
| Fastest Bus | 8h 20m |
| Earliest Bus | 2:50 AM |
| Latest Bus | 2:20 PM |
| Daily Bus Routes | 3 Ø |
| Distance | 188.3 miles |
| Bus Companies | Greyhound US |
Cheapest bus connections from Louisville, KY to Knoxville, TN
Every day, 3 buses from 1 bus companies leave Louisville, KY for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/14/2025 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
12/14
Monday
12/15
Tuesday
12/16
$66
Wednesday
12/17
Thursday
12/18
Friday
12/19
Saturday
12/20
Sunday
12/21
$103
Monday
12/22
Tuesday
12/23
Wednesday
12/24
Thursday
12/25
Friday
12/26
Saturday
12/27
Sunday
12/28
Monday
12/29
Tuesday
12/30
Wednesday
12/31
Thursday
01/01
Friday
01/02
Saturday
01/03
Sunday
01/04
Monday
01/05
Tuesday
01/06
Wednesday
01/07
Thursday
01/08
Friday
01/09
Saturday
01/10
How to save money travelling from Louisville, KY to Knoxville, TN
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Louisville, KY to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Louisville, KY to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Louisville, KY to Knoxville, TN are also emptier.All bus stations and stops in Louisville, KY and Knoxville, TN
In the map below, you can see where to find all bus stations in Louisville, KY and Knoxville, TN.
Service and Comfort on the bus from Louisville, KY to Knoxville, TN
Want to know which seat classes are available on the buses from Louisville, KY to Knoxville, TN? Or which bus companies serve the route Louisville, KY to Knoxville, TN? Below you will find answers to your questions.
FAQs about the Louisville, KY to Knoxville, TN bus
How much does a Louisville, KY Knoxville, TN bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $66 and takes 16h 5m to reach Knoxville, TN. Compare offers to save money!
How much could I save by comparing buses from Louisville, KY to Knoxville, TN?
This route is offered by 1 companies with a range of ticket prices between $66 and $67. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.
On average, how many connections are available from Louisville, KY to Knoxville, TN each day?
Every day, the Louisville, KY to Knoxville, TN bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Louisville, KY to Knoxville, TN take?
The fastest bus from Louisville, KY to Knoxville, TN is offered by Greyhound US and takes 8h 20m. Bus tickets for this connection cost $67. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Louisville, KY to Knoxville, TN?
The earliest bus arriving in Knoxville, TN from Louisville, KY starts at 2:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Louisville, KY to Knoxville, TN?
The latest bus trip departing from Louisville, KY for Knoxville, TN starts at 2:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Louisville, KY Knoxville, TN route?
When traveling by bus from Louisville, KY to Knoxville, TN, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Louisville, KY and Knoxville, TN?
You can check all the direct connections between Louisville, KY and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.
What can I take with me on the Louisville, KY to Knoxville, TN bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Louisville, KY Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Louisville, KY Knoxville, TN bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Louisville, KY to Knoxville, TN on your planned travel date.
Available seat classes which are offered on the bus route Louisville, KY to Knoxville, TN
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Louisville, KY and to Knoxville, TN
Here’s an overview of the most popular bus routes to Louisville, KY and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
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- Bus Routes to Knoxville, TN
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Popular Airport Shuttles to Louisville, KY and to Knoxville, TN
