Bus Houston to Louisville, KY - Compare all Companies

Compare all timetables for the bus from Houston to Louisville, KY

Here is a selection of the cheapest bus trips from the schedule from Houston to Louisville, KY from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.

today

tomorrow

$172

Saturday

Sunday

$186

Monday

Tuesday

$171

Wednesday

$169

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	28h 50m	10:50 PM	Houston	Downtown Houston	4:40 AM	Louisville, KY	Greyhound Bus Station	Economy	$172	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/19/2025 10:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/21/2025 4:40:00 AM. 50 Economy ticket for $172 per person are available. Travel duration is 28h 50m
Greyhound US	24h 20m	8:15 AM	Houston	Harrisburg Blvd Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$177	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/19/2025 8:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/20/2025 9:35:00 AM. 50 Economy ticket for $177 per person are available. Travel duration is 24h 20m
Greyhound US	26h 30m	10:00 PM	Houston	Harrisburg Blvd Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$189	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/19/2025 10:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/21/2025 1:30:00 AM. 50 Economy ticket for $189 per person are available. Travel duration is 26h 30m
FlixBus	28h 35m	1:45 PM	Houston	Downtown Houston	7:20 PM	Louisville, KY	Greyhound Bus Station	Economy	$193	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/19/2025 1:45:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/20/2025 7:20:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 28h 35m
Greyhound Lines Mexico	39h 0m	9:30 AM	Houston	SW Agencia Autobuses	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$311	A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/19/2025 9:30:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/21/2025 1:30:00 AM. 50 Economy ticket for $311 per person are available. Travel duration is 39h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	28h 50m	10:50 PM	Houston	Downtown Houston	4:40 AM	Louisville, KY	Greyhound Bus Station	Economy	$186	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/21/2025 10:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/23/2025 4:40:00 AM. 50 Economy ticket for $186 per person are available. Travel duration is 28h 50m
Greyhound US	26h 30m	10:00 PM	Houston	Harrisburg Blvd Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$187	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/21/2025 10:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/23/2025 1:30:00 AM. 50 Economy ticket for $187 per person are available. Travel duration is 26h 30m
FlixBus	31h 50m	8:55 AM	Houston	Uptown/Upper Kirby	5:45 PM	Louisville, KY	Greyhound Bus Station	Economy	$191	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/21/2025 8:55:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/22/2025 5:45:00 PM. 50 Economy ticket for $191 per person are available. Travel duration is 31h 50m
Greyhound US	23h 0m	2:10 PM	Houston	Harrisburg Blvd Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$192	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/21/2025 2:10:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/22/2025 2:10:00 PM. 50 Economy ticket for $192 per person are available. Travel duration is 23h 0m
Greyhound Lines Mexico	39h 0m	9:30 AM	Houston	SW Agencia Autobuses	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$260	A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/21/2025 9:30:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/23/2025 1:30:00 AM. 50 Economy ticket for $260 per person are available. Travel duration is 39h 0m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	26h 30m	10:00 PM	Houston	Harrisburg Blvd Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$171	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/23/2025 10:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/25/2025 1:30:00 AM. 50 Economy ticket for $171 per person are available. Travel duration is 26h 30m
Greyhound US	22h 40m	1:50 AM	Houston	Harrisburg Blvd Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$172	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/23/2025 1:50:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/24/2025 1:30:00 AM. 50 Economy ticket for $172 per person are available. Travel duration is 22h 40m
Greyhound US	23h 0m	2:10 PM	Houston	Harrisburg Blvd Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$173	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/23/2025 2:10:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/24/2025 2:10:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 23h 0m
FlixBus	30h 35m	6:35 AM	Houston	SW Agencia Autobuses	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$173	A Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 12/23/2025 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/24/2025 2:10:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 30h 35m
FlixBus	28h 40m	7:50 PM	Houston	Uptown/Upper Kirby	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$179	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/23/2025 7:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/25/2025 1:30:00 AM. 50 Economy ticket for $179 per person are available. Travel duration is 28h 40m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	23h 0m	2:10 PM	Houston	Harrisburg Blvd Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$169	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/24/2025 2:10:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/25/2025 2:10:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 23h 0m
FlixBus	30h 35m	6:35 AM	Houston	SW Agencia Autobuses	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$169	A Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 12/24/2025 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/25/2025 2:10:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 30h 35m
FlixBus	25h 45m	11:25 AM	Houston	Uptown/Upper Kirby	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$169	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/24/2025 11:25:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/25/2025 2:10:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 25h 45m
Greyhound US	22h 40m	1:50 AM	Houston	Harrisburg Blvd Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$170	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/24/2025 1:50:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/25/2025 1:30:00 AM. 50 Economy ticket for $170 per person are available. Travel duration is 22h 40m
Greyhound Lines Mexico	39h 0m	9:30 AM	Houston	SW Agencia Autobuses	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$176	A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/24/2025 9:30:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/26/2025 1:30:00 AM. 50 Economy ticket for $176 per person are available. Travel duration is 39h 0m

Best Price Offer: The price for the cheapest bus from Houston to Louisville, KY is $126 on 12/15/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Houston and Louisville, KY

See here how frequent the connections between Houston and Louisville, KY are, during different times and days of the week.

Sunday is the busiest day, with more than 14 daily buses from Houston to Louisville, KY. Tuesday has instead the fewest connections, with only 9 daily coaches between Houston and Louisville, KY.

The busiest time of the day is the Morning, with 21 buses from Houston to Louisville, KY, while Night sees the fewest connections between Houston and Louisville, KY, with 4 offers.

Facts about the bus from Houston to Louisville, KY

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 11 times every day by bus from Houston to Louisville, KY in one click! Book your bus ticket from Houston to Louisville, KY starting from $126!

Cheapest Bus	$126
Fastest Bus	23h 40m
Earliest Bus	1:50 AM
Latest Bus	10:50 PM
Daily Bus Routes	11 Ø
Distance	804.3 miles
Bus Companies	FlixBus, Greyhound US and Greyhound Lines Mexico

Cheapest bus connections from Houston to Louisville, KY

Every day, 11 buses from 3 bus companies leave Houston for Louisville, KY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/18/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

$172

Saturday 12/20

Sunday 12/21

$186

Monday 12/22

Tuesday 12/23

$171

Wednesday 12/24

$169

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Houston to Louisville, KY

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to Louisville, KY, for the next 30 days.

With a price starting from $169, Wednesday is the cheapest day for a bus from Houston to Louisville, KY. Sunday instead is the most expensive day with prices starting from $186.

Morning is the cheapest day time for bus tickets from Houston to Louisville, KY, with $169. Evening is the most expensive time of the day with prices starting from $171.

How to save money travelling from Houston to Louisville, KY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to Louisville, KY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to Louisville, KY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to Louisville, KY are also emptier.

All bus stations and stops in Houston and Louisville, KY

In the map below, you can see where to find all bus stations in Houston and Louisville, KY.

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Uptown/Upper Kirby

Southwest Fwy 2525

Chase Bank

Milam Street 212

Greyhound Bus Station

W Muhammad Ali Blvd 720

Convention Center

S 3rd St 300

BP Gas Station

Newburg Rd 3301

W Muhammad Ali Blvd

East Broadway, under the I-65 overpass between S 1st Street and S Brook Street

International Airport

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Houston to Louisville, KY? Compare all modes of transports from Houston to Louisville, KY.

Service and Comfort on the bus from Houston to Louisville, KY

Want to know which seat classes are available on the buses from Houston to Louisville, KY? Or which bus companies serve the route Houston to Louisville, KY? Below you will find answers to your questions.

FAQs about the Houston to Louisville, KY bus

How much does a Houston Louisville, KY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $126 and takes 31h 35m to reach Louisville, KY. Compare offers to save money!

How much could I save by comparing buses from Houston to Louisville, KY?

This route is offered by 3 companies with a range of ticket prices between $126 and $311. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Louisville, KY.

On average, how many connections are available from Houston to Louisville, KY each day?

Every day, the Houston to Louisville, KY bus route is served by approximately 11 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to Louisville, KY take?

The fastest bus from Houston to Louisville, KY is offered by Greyhound US and takes 23h 40m. Bus tickets for this connection cost $201. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to Louisville, KY?

The earliest bus arriving in Louisville, KY from Houston starts at 1:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to Louisville, KY?

The latest bus trip departing from Houston for Louisville, KY starts at 10:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston Louisville, KY route?

When traveling by bus from Houston to Louisville, KY, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and Louisville, KY?

You can check all the direct connections between Houston and Louisville, KY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the Houston to Louisville, KY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston Louisville, KY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston Louisville, KY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to Louisville, KY on your planned travel date.

How does CheckMyBus find the best bus deals from Houston to Louisville, KY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 11 daily trips between Houston and Louisville, KY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Houston to Louisville, KY?

Prices and availability for 11 trips between Houston and Louisville, KY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Houston to Louisville, KY

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to Louisville, KY

Here’s an overview of the most popular bus routes to Houston and to Louisville, KY. Simply click on the connection of your choice, and you will find all the details about your bus route!