Bus Houston to Louisville, KY - Compare all Companies

Compare all timetables for the bus from Houston to Louisville, KY

Here is a selection of the cheapest bus trips from the schedule from Houston to Louisville, KY from various bus operators like FlixBus, Greyhound US or Valley Transit for the next days.

today

tomorrow

$111

Saturday

$120

Sunday

$111

Monday

$105

Tuesday

$110

Wednesday

$128

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	29h 55m	7:15 AM	Houston	Uptown/Upper Kirby	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$111	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/8/2026 7:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/9/2026 2:10:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 29h 55m
Greyhound US	24h 20m	8:15 AM	Houston	Harrisburg Blvd Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$112	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/8/2026 8:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/9/2026 9:35:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 24h 20m
Greyhound US	26h 30m	10:00 PM	Houston	Harrisburg Blvd Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$112	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/8/2026 10:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/10/2026 1:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 26h 30m
Valley Transit	30h 35m	6:35 AM	Houston	SW Agencia Autobuses	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$112	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 5/8/2026 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/9/2026 2:10:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 30h 35m
FlixBus	32h 5m	8:55 AM	Houston	Uptown/Upper Kirby	6:00 PM	Louisville, KY	Greyhound Bus Station	Economy	$112	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/8/2026 8:55:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/9/2026 6:00:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 32h 5m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	22h 40m	1:50 AM	Houston	Harrisburg Blvd Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$120	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/9/2026 1:50:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/10/2026 1:30:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 22h 40m
Greyhound US	24h 20m	8:15 AM	Houston	Harrisburg Blvd Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$120	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/9/2026 8:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/10/2026 9:35:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 24h 20m
Valley Transit	30h 35m	6:35 AM	Houston	SW Agencia Autobuses	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$120	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 5/9/2026 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/10/2026 2:10:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 30h 35m
FlixBus	28h 40m	7:50 PM	Houston	Uptown/Upper Kirby	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$120	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/9/2026 7:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/11/2026 1:30:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 28h 40m
FlixBus	28h 55m	7:35 PM	Houston	Downtown Houston	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$120	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 5/9/2026 7:35:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/11/2026 1:30:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 28h 55m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	29h 55m	7:15 AM	Houston	Uptown/Upper Kirby	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$111	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/10/2026 7:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/11/2026 2:10:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 29h 55m
Greyhound US	22h 40m	1:50 AM	Houston	Harrisburg Blvd Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$112	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/10/2026 1:50:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/11/2026 1:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 22h 40m
Greyhound US	24h 20m	8:15 AM	Houston	Harrisburg Blvd Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$112	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/10/2026 8:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/11/2026 9:35:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 24h 20m
Valley Transit	30h 35m	6:35 AM	Houston	SW Agencia Autobuses	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$112	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 5/10/2026 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/11/2026 2:10:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 30h 35m
FlixBus	32h 5m	8:55 AM	Houston	Uptown/Upper Kirby	6:00 PM	Louisville, KY	Greyhound Bus Station	Economy	$112	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/10/2026 8:55:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/11/2026 6:00:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 32h 5m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 55m	1:15 PM	Houston	Downtown Houston	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$105	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 5/11/2026 1:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/12/2026 2:10:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 23h 55m
Greyhound US	22h 40m	1:50 AM	Houston	Harrisburg Blvd Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$106	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/11/2026 1:50:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/12/2026 1:30:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 22h 40m
Greyhound US	24h 20m	8:15 AM	Houston	Harrisburg Blvd Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$106	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/11/2026 8:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/12/2026 9:35:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 24h 20m
FlixBus	25h 45m	11:25 AM	Houston	Uptown/Upper Kirby	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$106	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/11/2026 11:25:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/12/2026 2:10:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 25h 45m
Valley Transit	30h 35m	6:35 AM	Houston	SW Agencia Autobuses	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$107	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 5/11/2026 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/12/2026 2:10:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 30h 35m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	22h 40m	1:50 AM	Houston	Harrisburg Blvd Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$110	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/12/2026 1:50:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/13/2026 1:30:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 22h 40m
Greyhound US	24h 20m	8:15 AM	Houston	Harrisburg Blvd Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$110	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/12/2026 8:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/13/2026 9:35:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 24h 20m
FlixBus	25h 45m	11:25 AM	Houston	Uptown/Upper Kirby	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$111	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/12/2026 11:25:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/13/2026 2:10:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 25h 45m
Valley Transit	30h 35m	6:35 AM	Houston	SW Agencia Autobuses	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$112	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 5/12/2026 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/13/2026 2:10:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 30h 35m
FlixBus	23h 55m	1:15 PM	Houston	Downtown Houston	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$112	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 5/12/2026 1:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/13/2026 2:10:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 23h 55m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	24h 20m	8:15 AM	Houston	Harrisburg Blvd Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$128	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/13/2026 8:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/14/2026 9:35:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 24h 20m
Greyhound US	26h 30m	10:00 PM	Houston	Harrisburg Blvd Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$128	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/13/2026 10:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/15/2026 1:30:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 26h 30m
FlixBus	26h 0m	11:10 AM	Houston	Downtown Houston	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$128	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 5/13/2026 11:10:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/14/2026 2:10:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 26h 0m
FlixBus	28h 50m	10:50 PM	Houston	Downtown Houston	4:40 AM	Louisville, KY	Greyhound Bus Station	Economy	$128	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 5/13/2026 10:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/15/2026 4:40:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 28h 50m
Valley Transit	30h 35m	6:35 AM	Houston	SW Agencia Autobuses	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$130	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 5/13/2026 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/14/2026 2:10:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 30h 35m

Did you know that if you travel from Houston to Louisville, KY via Baytown, TX, you can save more than $17? You can find the corresponding connections below.
- Greyhound US
  
  29h 15m
  
  0
  
  1:05 PM
  
  Houston
  Harrisburg Blvd Station
  
  1:35 PM
  
  Baytown, TX
  Travel Express
  
  0
  
  Economy
  
  $4
  
  A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/14/2026 1:05:00 PM to Travel Express, Baytown, TX (USA) arriving at 5/14/2026 1:35:00 PM. 50 Economy ticket for $4 per person are available. Travel duration is 0h 30m
- Greyhound US
  
  28h 40m
  
  0
  
  1:40 PM
  
  Baytown, TX
  Travel Express
  
  7:20 PM
  
  Louisville, KY
  Greyhound Bus Station
  
  0
  
  Economy
  
  $107
  
  A Bus from Greyhound US goes from Travel Express, Baytown, TX (USA) at 5/14/2026 1:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 5/15/2026 7:20:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 28h 40m
Travel time is 3h 55m longer, but you will save $17

Best Price Offer: The price for the cheapest bus from Houston to Louisville, KY is $105 on 5/11/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Houston and Louisville, KY

See here how frequent the connections between Houston and Louisville, KY are, during different times and days of the week.

Saturday is the busiest day, with more than 24 daily buses from Houston to Louisville, KY. Sunday has instead the fewest connections, with only 13 daily coaches between Houston and Louisville, KY.

The busiest time of the day is the Evening, with 34 buses from Houston to Louisville, KY, while Night sees the fewest connections between Houston and Louisville, KY, with 10 offers.

Facts about the bus from Houston to Louisville, KY

Compare all providers like FlixBus, Greyhound US and Valley Transit that travel 17 times every day by bus from Houston to Louisville, KY in one click! Book your bus ticket from Houston to Louisville, KY starting from $105!

Cheapest Bus	$105
Fastest Bus	23h 40m
Earliest Bus	1:50 AM
Latest Bus	10:50 PM
Daily Bus Routes	17 Ø
Distance	804.3 miles
Bus Companies	FlixBus, Greyhound US and Valley Transit

Cheapest bus connections from Houston to Louisville, KY

Every day, 17 buses from 3 bus companies leave Houston for Louisville, KY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/07/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/03

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$111

Saturday 05/09

$120

Sunday 05/10

$111

Monday 05/11

$109

Tuesday 05/12

$110

Wednesday 05/13

$128

Thursday 05/14

$121

Friday 05/15

$118

Saturday 05/16

$130

Sunday 05/17

$118

Monday 05/18

$118

Tuesday 05/19

$125

Wednesday 05/20

$112

Thursday 05/21

$122

Friday 05/22

$120

Saturday 05/23

$117

Sunday 05/24

$112

Monday 05/25

$118

Tuesday 05/26

$111

Wednesday 05/27

$107

Thursday 05/28

$108

Friday 05/29

$106

Saturday 05/30

The cheapest time to travel from Houston to Louisville, KY

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to Louisville, KY, for the next 30 days.

With a price starting from $101, Sunday is the cheapest day for a bus from Houston to Louisville, KY. Saturday instead is the most expensive day with prices starting from $111.

Night is the cheapest day time for bus tickets from Houston to Louisville, KY, with $101. Evening is the most expensive time of the day with prices starting from $106.

How to save money travelling from Houston to Louisville, KY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to Louisville, KY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to Louisville, KY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to Louisville, KY are also emptier.

All bus stations and stops in Houston and Louisville, KY

In the map below, you can see where to find all bus stations in Houston and Louisville, KY.

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Chase Bank

Milam Street 212

Uptown/Upper Kirby

Southwest Fwy 2525

Greyhound Bus Station

W Muhammad Ali Blvd 720

Convention Center

S 3rd St 300

BP Gas Station

Newburg Rd 3301

W Muhammad Ali Blvd

East Broadway, under the I-65 overpass between S 1st Street and S Brook Street

International Airport

Service and Comfort on the bus from Houston to Louisville, KY

Want to know which seat classes are available on the buses from Houston to Louisville, KY? Or which bus companies serve the route Houston to Louisville, KY? Below you will find answers to your questions.

FAQs about the Houston to Louisville, KY bus

How much does a Houston Louisville, KY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $105 and takes 24h 55m to reach Louisville, KY. Compare offers to save money!

How much could I save by comparing buses from Houston to Louisville, KY?

This route is offered by 3 companies with a range of ticket prices between $105 and $150. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Louisville, KY.

On average, how many connections are available from Houston to Louisville, KY each day?

Every day, the Houston to Louisville, KY bus route is served by approximately 17 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to Louisville, KY take?

The fastest bus from Houston to Louisville, KY is offered by Greyhound US and takes 23h 40m. Bus tickets for this connection cost $121. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to Louisville, KY?

The earliest bus arriving in Louisville, KY from Houston starts at 1:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to Louisville, KY?

The latest bus trip departing from Houston for Louisville, KY starts at 10:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston Louisville, KY route?

When traveling by bus from Houston to Louisville, KY, passengers can travel with FlixBus, Greyhound US and Valley Transit. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and Louisville, KY?

You can check all the direct connections between Houston and Louisville, KY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Valley Transit.

What can I take with me on the Houston to Louisville, KY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston Louisville, KY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston Louisville, KY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to Louisville, KY on your planned travel date.

How does CheckMyBus find the best bus deals from Houston to Louisville, KY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 17 daily trips between Houston and Louisville, KY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Houston to Louisville, KY?

Prices and availability for 17 trips between Houston and Louisville, KY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Houston to Louisville, KY

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to Louisville, KY

Here’s an overview of the most popular bus routes to Houston and to Louisville, KY. Simply click on the connection of your choice, and you will find all the details about your bus route!