What is the best way to travel from Houston to Louisville, KY?
Looking for a trip? Compare all the available Buses and Flights for the journey to Louisville, KY from Houston. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Louisville, KY from Houston?
You can get to Louisville, KY with just $131 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Greyhound US23h 0m02:10 PMHoustonHarrisburg Blvd Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/6/2025 2:10:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 2:10:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 23h 0m
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Greyhound US22h 30m02:00 AMHoustonHarrisburg Blvd Station1:30 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/6/2025 2:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 1:30:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 22h 30m
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FlixBus30h 35m06:35 AMHoustonSW Agencia Autobuses2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 12/6/2025 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 2:10:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 30h 35m
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FlixBus25h 45m011:25 AMHoustonUptown/Upper Kirby2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/6/2025 11:25:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 2:10:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 25h 45m
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Greyhound Lines Mexico39h 0m09:30 AMHoustonSW Agencia Autobuses1:30 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/6/2025 9:30:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/8/2025 1:30:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 39h 0m
Cheapest Buses Saturday
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Greyhound US23h 0m02:10 PMHoustonHarrisburg Blvd Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/8/2025 2:10:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 2:10:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 23h 0m
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Greyhound US26h 30m010:00 PMHoustonHarrisburg Blvd Station1:30 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/8/2025 10:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/10/2025 1:30:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 26h 30m
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Greyhound US24h 15m08:20 AMHoustonHarrisburg Blvd Station9:35 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/8/2025 8:20:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 9:35:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 24h 15m
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FlixBus25h 45m011:25 AMHoustonUptown/Upper Kirby2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/8/2025 11:25:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 2:10:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 25h 45m
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FlixBus29h 5m01:15 PMHoustonUptown/Upper Kirby7:20 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/8/2025 1:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 7:20:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 29h 5m
Cheapest Buses Monday
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Greyhound US23h 0m02:10 PMHoustonHarrisburg Blvd Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/10/2025 2:10:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 2:10:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 23h 0m
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FlixBus25h 45m011:25 AMHoustonUptown/Upper Kirby2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/10/2025 11:25:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 2:10:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 25h 45m
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FlixBus30h 35m06:35 AMHoustonSW Agencia Autobuses2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 12/10/2025 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 2:10:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 30h 35m
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Greyhound US22h 40m01:50 AMHoustonHarrisburg Blvd Station1:30 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/10/2025 1:50:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 1:30:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 22h 40m
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Greyhound Lines Mexico39h 0m09:30 AMHoustonSW Agencia Autobuses1:30 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/10/2025 9:30:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 1:30:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 39h 0m
Cheapest Buses Wednesday
What are the fastest trips from Houston to Louisville, KY?
You can get to Louisville, KY from Houston in just 22h 30m with a Bus from Greyhound US. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Greyhound US22h 30m02:00 AMHoustonHarrisburg Blvd Station1:30 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/6/2025 2:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 1:30:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 22h 30m
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Greyhound US23h 0m02:10 PMHoustonHarrisburg Blvd Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/6/2025 2:10:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 2:10:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 23h 0m
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FlixBus25h 45m011:25 AMHoustonUptown/Upper Kirby2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/6/2025 11:25:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 2:10:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 25h 45m
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FlixBus30h 35m06:35 AMHoustonSW Agencia Autobuses2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 12/6/2025 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 2:10:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 30h 35m
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Greyhound Lines Mexico39h 0m09:30 AMHoustonSW Agencia Autobuses1:30 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/6/2025 9:30:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/8/2025 1:30:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 39h 0m
Fastest Buses Saturday
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Greyhound US23h 0m02:10 PMHoustonHarrisburg Blvd Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/8/2025 2:10:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 2:10:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 23h 0m
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Greyhound US24h 15m08:20 AMHoustonHarrisburg Blvd Station9:35 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/8/2025 8:20:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 9:35:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 24h 15m
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FlixBus25h 45m011:25 AMHoustonUptown/Upper Kirby2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/8/2025 11:25:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 2:10:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 25h 45m
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Greyhound US26h 30m010:00 PMHoustonHarrisburg Blvd Station1:30 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/8/2025 10:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/10/2025 1:30:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 26h 30m
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FlixBus29h 5m01:15 PMHoustonUptown/Upper Kirby7:20 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/8/2025 1:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 7:20:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 29h 5m
Fastest Buses Monday
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Greyhound US22h 40m01:50 AMHoustonHarrisburg Blvd Station1:30 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/10/2025 1:50:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 1:30:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 22h 40m
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Greyhound US23h 0m02:10 PMHoustonHarrisburg Blvd Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/10/2025 2:10:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 2:10:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 23h 0m
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FlixBus25h 45m011:25 AMHoustonUptown/Upper Kirby2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/10/2025 11:25:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 2:10:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 25h 45m
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FlixBus30h 35m06:35 AMHoustonSW Agencia Autobuses2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 12/10/2025 6:35:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 2:10:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 30h 35m
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Greyhound Lines Mexico39h 0m09:30 AMHoustonSW Agencia Autobuses1:30 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/10/2025 9:30:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 1:30:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 39h 0m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Houston to Louisville, KY
What are the most popular stations in Houston and Louisville, KY?
In Houston, you will usually depart from Hillcroft METRO Park and Ride Bus Station, Lockwood or Main St & Airline Dr, while in Louisville, KY you will be arriving at Greyhound Bus Station, International Airport or Convention Center, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Louisville, KY from Houston? With 5 connections between 3 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Houston and Louisville, KY, you can pay as low as $131 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from Greyhound US: you will get to Louisville, KY in just 22h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Houston and Louisville, KY are Greyhound US, FlixBus and Greyhound Lines Mexico, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Houston and Louisville, KY is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from West University Place, TX or to New Albany, IN, and look at flights from William P. Hobby Airport, and landing at . Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Houston to Louisville, KY?
The most popular companies between Houston and Louisville, KY, are Greyhound US, FlixBus and Greyhound Lines Mexico. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US, FlixBus and Greyhound Lines Mexico
All you need to know when you travel from Houston to Louisville, KY
Check all information on comfort and services on all modes of transports from Houston to Louisville, KY. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Houston to Louisville, KY
How can I reach Louisville, KY from Houston?
Every day, there are on average 5 connections between Bus and Flight, with which you can get to Louisville, KY from Houston.
How far is Louisville, KY from Houston?
The distance between Houston and Louisville, KY is 804.3 miles.
What is the most ecofriendly mode of transport between Houston and Louisville, KY?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 35 kgs of CO2, a train 45 kgs, a car 220 kgs, and a flight 318 kgs.
What is the cheapest mode of transport from Houston to Louisville, KY?
You can get to Louisville, KY with just $131 by taking a Bus from Greyhound US.
What is the fastest way to get from Houston to Louisville, KY?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Louisville, KY in just 22h 30m with a Bus from Greyhound US.
More routes to Houston and to Louisville, KY
Looking for more options? Here you can see the most popular routes to Houston and to Louisville, KY. Simply click on a connection, and you’ll find all the details about the route!
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