What is the best way to travel from Orlando, FL to Louisville, KY?
Looking for a trip? Compare all the available Buses and Flights for the journey to Louisville, KY from Orlando, FL. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Louisville, KY from Orlando, FL?
You can get to Louisville, KY with just $107 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus19h 30m06:00 AMOrlando, FLBus Station1:30 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/6/2025 6:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 1:30:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 19h 30m
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FlixBus18h 40m010:00 AMOrlando, FLBus Station4:40 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/6/2025 10:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 4:40:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 18h 40m
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FlixBus18h 55m012:30 PMOrlando, FLBus Station7:25 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/6/2025 12:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 7:25:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 18h 55m
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Greyhound US17h 30m08:40 PMOrlando, FLBus Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/6/2025 8:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 2:10:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 17h 30m
Cheapest Buses Saturday
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FlixBus18h 40m010:00 AMOrlando, FLBus Station4:40 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/8/2025 10:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 4:40:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 18h 40m
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FlixBus18h 55m012:30 PMOrlando, FLBus Station7:25 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/8/2025 12:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 7:25:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 18h 55m
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FlixBus18h 50m02:45 PMOrlando, FLBus Station9:35 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/8/2025 2:45:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 9:35:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 18h 50m
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Greyhound US17h 30m08:40 PMOrlando, FLBus Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/8/2025 8:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 2:10:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 17h 30m
Cheapest Buses Monday
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FlixBus20h 25m010:55 PMOrlando, FLBus Station7:20 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/10/2025 10:55:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 7:20:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 20h 25m
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Greyhound US17h 30m08:40 PMOrlando, FLBus Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/10/2025 8:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 2:10:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 17h 30m
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FlixBus18h 40m010:00 AMOrlando, FLBus Station4:40 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/10/2025 10:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 4:40:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 18h 40m
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FlixBus18h 55m012:30 PMOrlando, FLBus Station7:25 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/10/2025 12:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 7:25:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 18h 55m
Cheapest Buses Wednesday
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FlixBus18h 40m010:00 AMOrlando, FLBus Station4:40 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/11/2025 10:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 4:40:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 18h 40m
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FlixBus18h 55m012:30 PMOrlando, FLBus Station7:25 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/11/2025 12:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 7:25:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 18h 55m
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FlixBus18h 50m02:45 PMOrlando, FLBus Station9:35 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/11/2025 2:45:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 9:35:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 18h 50m
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Greyhound US17h 30m08:40 PMOrlando, FLBus Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/11/2025 8:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 2:10:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 17h 30m
Cheapest Buses Thursday
What are the fastest trips from Orlando, FL to Louisville, KY?
You can get to Louisville, KY from Orlando, FL in just 17h 30m with a Bus from Greyhound US. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Greyhound US17h 30m08:40 PMOrlando, FLBus Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/6/2025 8:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 2:10:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 17h 30m
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FlixBus18h 40m010:00 AMOrlando, FLBus Station4:40 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/6/2025 10:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 4:40:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 18h 40m
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FlixBus18h 55m012:30 PMOrlando, FLBus Station7:25 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/6/2025 12:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 7:25:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 18h 55m
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FlixBus19h 30m06:00 AMOrlando, FLBus Station1:30 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/6/2025 6:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 1:30:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 19h 30m
Fastest Buses Saturday
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Greyhound US17h 30m08:40 PMOrlando, FLBus Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/8/2025 8:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 2:10:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 17h 30m
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FlixBus18h 40m010:00 AMOrlando, FLBus Station4:40 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/8/2025 10:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 4:40:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 18h 40m
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FlixBus18h 50m02:45 PMOrlando, FLBus Station9:35 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/8/2025 2:45:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 9:35:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 18h 50m
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FlixBus18h 55m012:30 PMOrlando, FLBus Station7:25 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/8/2025 12:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 7:25:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 18h 55m
Fastest Buses Monday
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Greyhound US17h 30m08:40 PMOrlando, FLBus Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/10/2025 8:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 2:10:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 17h 30m
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FlixBus18h 40m010:00 AMOrlando, FLBus Station4:40 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/10/2025 10:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 4:40:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 18h 40m
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FlixBus18h 55m012:30 PMOrlando, FLBus Station7:25 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/10/2025 12:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 7:25:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 18h 55m
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FlixBus20h 25m010:55 PMOrlando, FLBus Station7:20 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/10/2025 10:55:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 7:20:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 20h 25m
Fastest Buses Wednesday
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Greyhound US17h 30m08:40 PMOrlando, FLBus Station2:10 PMLouisville, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/11/2025 8:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 2:10:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 17h 30m
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FlixBus18h 40m010:00 AMOrlando, FLBus Station4:40 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/11/2025 10:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 4:40:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 18h 40m
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FlixBus18h 50m02:45 PMOrlando, FLBus Station9:35 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/11/2025 2:45:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 9:35:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 18h 50m
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FlixBus18h 55m012:30 PMOrlando, FLBus Station7:25 AMLouisville, KYGreyhound Bus Station0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/11/2025 12:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 7:25:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 18h 55m
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Orlando, FL to Louisville, KY
What are the most popular stations in Orlando, FL and Louisville, KY?
In Orlando, FL, you will usually depart from Bus Station, Dahlia Dr and S Semoran Blvd Bus Stop or Central Station, while in Louisville, KY you will be arriving at Greyhound Bus Station, International Airport or Convention Center, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Louisville, KY from Orlando, FL? With 4 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Orlando, FL and Louisville, KY, you can pay as low as $107 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from Greyhound US: you will get to Louisville, KY in just 17h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Orlando, FL and Louisville, KY are FlixBus and Greyhound US, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Orlando, FL and Louisville, KY is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Fairview Shores, FL or to New Albany, IN, and look at flights from Orlando Airport, and landing at . Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Orlando, FL to Louisville, KY?
The most popular companies between Orlando, FL and Louisville, KY, are FlixBus and Greyhound US. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and Greyhound US
All you need to know when you travel from Orlando, FL to Louisville, KY
Check all information on comfort and services on all modes of transports from Orlando, FL to Louisville, KY. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Orlando, FL to Louisville, KY
How can I reach Louisville, KY from Orlando, FL?
Every day, there are on average 4 connections between Bus and Flight, with which you can get to Louisville, KY from Orlando, FL.
How far is Louisville, KY from Orlando, FL?
The distance between Orlando, FL and Louisville, KY is 717.2 miles.
What is the most ecofriendly mode of transport between Orlando, FL and Louisville, KY?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 31 kgs of CO2, a train 40 kgs, a car 196 kgs, and a flight 284 kgs.
What is the cheapest mode of transport from Orlando, FL to Louisville, KY?
You can get to Louisville, KY with just $107 by taking a Bus from FlixBus.
What is the fastest way to get from Orlando, FL to Louisville, KY?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Louisville, KY in just 17h 30m with a Bus from Greyhound US.
More routes to Orlando, FL and to Louisville, KY
Looking for more options? Here you can see the most popular routes to Orlando, FL and to Louisville, KY. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Orlando, FL
- Atlanta, GA to Orlando, FL
- Baltimore, MD to Orlando, FL
- Boston, MA to Orlando, FL
- Charlotte to Orlando, FL
- Chicago to Orlando, FL
- Cincinnati to Orlando, FL
- Columbus, OH to Orlando, FL
- Dallas to Orlando, FL
- Fort Lauderdale Airport to Orlando, FL
- Houston to Orlando, FL
- Miami Airport to Orlando, FL
- Miami Beach, FL to Orlando, FL
- Miami to Orlando, FL
- Monterrey, NL to Orlando, FL
- New York to Orlando, FL
- Newark to Orlando, FL
- Philadelphia to Orlando, FL
- Providence, RI to Orlando, FL
- Syracuse, NY to Orlando, FL
- West Palm Beach, FL to Orlando, FL

