Bus Orlando, FL to Louisville, KY: Compare prices and save money

Compare all timetables for the bus from Orlando, FL to Louisville, KY

Here is a selection of the cheapest bus trips from the schedule from Orlando, FL to Louisville, KY from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$117

Sunday

Monday

$139

Tuesday

Wednesday

$107

Thursday

$141

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 30m	6:00 AM	Orlando, FL	Bus Station	1:30 AM	Louisville, KY	Greyhound Bus Station	Economy	$117	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/6/2025 6:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 1:30:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 19h 30m
FlixBus	18h 40m	10:00 AM	Orlando, FL	Bus Station	4:40 AM	Louisville, KY	Greyhound Bus Station	Economy	$117	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/6/2025 10:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 4:40:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 18h 40m
FlixBus	18h 55m	12:30 PM	Orlando, FL	Bus Station	7:25 AM	Louisville, KY	Greyhound Bus Station	Economy	$117	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/6/2025 12:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 7:25:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 18h 55m
Greyhound US	17h 30m	8:40 PM	Orlando, FL	Bus Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$117	A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/6/2025 8:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/7/2025 2:10:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 17h 30m

Did you know that if you travel from Orlando, FL to Louisville, KY via Atlanta, GA, you can save more than $15? You can find the corresponding connections below.
- Busbud
  
  21h 5m
  
  0
  
  12:30 PM
  
  Orlando, FL
  Bus Station
  
  9:15 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $51
  
  A Bus from Busbud goes from Bus Station, Orlando, FL (USA) at 12/7/2025 12:30:00 PM to Garnett Transit Station, Atlanta, GA (USA) arriving at 12/7/2025 9:15:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 8h 45m
- FlixBus
  
  9h 20m
  
  0
  
  12:15 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  9:35 AM
  
  Louisville, KY
  Greyhound Bus Station
  
  0
  
  Economy
  
  $51
  
  A Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 12/8/2025 12:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/8/2025 9:35:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 9h 20m
Travel time is 3h 35m longer, but you will save $15

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	18h 40m	10:00 AM	Orlando, FL	Bus Station	4:40 AM	Louisville, KY	Greyhound Bus Station	Economy	$139	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/8/2025 10:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 4:40:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 18h 40m
FlixBus	18h 55m	12:30 PM	Orlando, FL	Bus Station	7:25 AM	Louisville, KY	Greyhound Bus Station	Economy	$139	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/8/2025 12:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 7:25:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 18h 55m
FlixBus	18h 50m	2:45 PM	Orlando, FL	Bus Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$139	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/8/2025 2:45:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 9:35:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 18h 50m
Greyhound US	17h 30m	8:40 PM	Orlando, FL	Bus Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$144	A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/8/2025 8:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/9/2025 2:10:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 17h 30m

Did you know that if you travel from Orlando, FL to Louisville, KY via Atlanta, GA, you can save more than $41? You can find the corresponding connections below.
- Busbud
  
  24h 35m
  
  0
  
  9:00 AM
  
  Orlando, FL
  Bus Station
  
  6:05 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $46
  
  A Bus from Busbud goes from Bus Station, Orlando, FL (USA) at 12/9/2025 9:00:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 12/9/2025 6:05:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 9h 5m
- FlixBus
  
  9h 20m
  
  0
  
  12:15 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  9:35 AM
  
  Louisville, KY
  Greyhound Bus Station
  
  0
  
  Economy
  
  $52
  
  A Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 12/10/2025 12:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/10/2025 9:35:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 9h 20m
Travel time is 7h 5m longer, but you will save $41

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 25m	10:55 PM	Orlando, FL	Bus Station	7:20 PM	Louisville, KY	Greyhound Bus Station	Economy	$107	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/10/2025 10:55:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 7:20:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 20h 25m
Greyhound US	17h 30m	8:40 PM	Orlando, FL	Bus Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$107	A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/10/2025 8:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 2:10:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 17h 30m
FlixBus	18h 40m	10:00 AM	Orlando, FL	Bus Station	4:40 AM	Louisville, KY	Greyhound Bus Station	Economy	$108	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/10/2025 10:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 4:40:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 18h 40m
FlixBus	18h 55m	12:30 PM	Orlando, FL	Bus Station	7:25 AM	Louisville, KY	Greyhound Bus Station	Economy	$108	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/10/2025 12:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/11/2025 7:25:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 18h 55m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	18h 40m	10:00 AM	Orlando, FL	Bus Station	4:40 AM	Louisville, KY	Greyhound Bus Station	Economy	$141	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/11/2025 10:00:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 4:40:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 18h 40m
FlixBus	18h 55m	12:30 PM	Orlando, FL	Bus Station	7:25 AM	Louisville, KY	Greyhound Bus Station	Economy	$141	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/11/2025 12:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 7:25:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 18h 55m
FlixBus	18h 50m	2:45 PM	Orlando, FL	Bus Station	9:35 AM	Louisville, KY	Greyhound Bus Station	Economy	$141	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/11/2025 2:45:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 9:35:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 18h 50m
Greyhound US	17h 30m	8:40 PM	Orlando, FL	Bus Station	2:10 PM	Louisville, KY	Greyhound Bus Station	Economy	$143	A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/11/2025 8:40:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/12/2025 2:10:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 17h 30m

Did you know that if you travel from Orlando, FL to Louisville, KY via Atlanta, GA, you can save more than $43? You can find the corresponding connections below.
- Busbud
  
  24h 35m
  
  0
  
  9:00 AM
  
  Orlando, FL
  Bus Station
  
  6:05 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $46
  
  A Bus from Busbud goes from Bus Station, Orlando, FL (USA) at 12/9/2025 9:00:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 12/9/2025 6:05:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 9h 5m
- FlixBus
  
  9h 20m
  
  0
  
  12:15 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  9:35 AM
  
  Louisville, KY
  Greyhound Bus Station
  
  0
  
  Economy
  
  $52
  
  A Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 12/10/2025 12:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/10/2025 9:35:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 9h 20m
Travel time is 7h 5m longer, but you will save $43

Best Price Offer: The price for the cheapest bus from Orlando, FL to Louisville, KY is $107 on 12/10/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Orlando, FL and Louisville, KY

See here how frequent the connections between Orlando, FL and Louisville, KY are, during different times and days of the week.

Monday is the busiest day, with more than 7 daily buses from Orlando, FL to Louisville, KY. Monday has instead the fewest connections, with only 7 daily coaches between Orlando, FL and Louisville, KY.

The busiest time of the day is the Afternoon, with 12 buses from Orlando, FL to Louisville, KY, while Morning sees the fewest connections between Orlando, FL and Louisville, KY, with 8 offers.

Facts about the bus from Orlando, FL to Louisville, KY

Compare all providers like FlixBus and Greyhound US that travel 7 times every day by bus from Orlando, FL to Louisville, KY in one click! Book your bus ticket from Orlando, FL to Louisville, KY starting from $107!

Cheapest Bus	$107
Fastest Bus	17h 30m
Earliest Bus	6:00 AM
Latest Bus	10:55 PM
Daily Bus Routes	7 Ø
Distance	717.2 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Orlando, FL to Louisville, KY

Every day, 7 buses from 2 bus companies leave Orlando, FL for Louisville, KY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

Saturday 12/06

$117

Sunday 12/07

Monday 12/08

$139

Tuesday 12/09

Wednesday 12/10

$107

Thursday 12/11

$141

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Orlando, FL to Louisville, KY

See here on which day and which time of the day you can find the cheapest bus ticket from Orlando, FL to Louisville, KY, for the next 30 days.

With a price starting from $107, Wednesday is the cheapest day for a bus from Orlando, FL to Louisville, KY. Thursday instead is the most expensive day with prices starting from $141.

Evening is the cheapest day time for bus tickets from Orlando, FL to Louisville, KY, with $107. Morning is the most expensive time of the day with prices starting from $108.

How to save money travelling from Orlando, FL to Louisville, KY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Orlando, FL to Louisville, KY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Orlando, FL to Louisville, KY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Orlando, FL to Louisville, KY are also emptier.

Beloved bus companies from Orlando, FL to Louisville, KY

These are the most booked bus companies between Orlando, FL to Louisville, KY from our users.

FlixBus from Orlando, FL to Louisville, KY

Here you will find the key facts about the FlixBus bus route Orlando, FL to Louisville, KY:

Cheapest Price	$107
Fastest Bus	18h 40m
Earliest Bus	6:00 AM
Last Bus	10:55 PM
Daily Connections	6 Ø
Found on	12/3/2025

Greyhound US from Orlando, FL to Louisville, KY

Here you will find the key facts about the Greyhound US bus route Orlando, FL to Louisville, KY:

Cheapest Price	$107
Fastest Bus	17h 30m
Earliest Bus	8:40 PM
Last Bus	8:40 PM
Daily Connections	1 Ø
Found on	12/3/2025

All bus stations and stops in Orlando, FL and Louisville, KY

In the map below, you can see where to find all bus stations in Orlando, FL and Louisville, KY.

Bus Station

N John Young Pkwy 555

Florida Mall

Florida Mall Avenue 1602

RedCoach Station

Belle Isle

Universal Studio Orlando Resort

Universal Blvd 5800

Jet Set Express Orlando Terminal

L B McLeod Rd 3718

Greyhound Bus Station

W Muhammad Ali Blvd 720

Convention Center

S 3rd St 300

BP Gas Station

Newburg Rd 3301

W Muhammad Ali Blvd

East Broadway, under the I-65 overpass between S 1st Street and S Brook Street

International Airport

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Orlando, FL to Louisville, KY? Compare all modes of transports from Orlando, FL to Louisville, KY.

Service and Comfort on the bus from Orlando, FL to Louisville, KY

Want to know which seat classes are available on the buses from Orlando, FL to Louisville, KY? Or which bus companies serve the route Orlando, FL to Louisville, KY? Below you will find answers to your questions.

FAQs about the Orlando, FL to Louisville, KY bus

How much does a Orlando, FL Louisville, KY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $107 and takes 17h 30m to reach Louisville, KY. Compare offers to save money!

How much could I save by comparing buses from Orlando, FL to Louisville, KY?

This route is offered by 2 companies with a range of ticket prices between $107 and $148. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Louisville, KY.

On average, how many connections are available from Orlando, FL to Louisville, KY each day?

Every day, the Orlando, FL to Louisville, KY bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Orlando, FL to Louisville, KY take?

The fastest bus from Orlando, FL to Louisville, KY is offered by Greyhound US and takes 17h 30m. Bus tickets for this connection cost $117. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Orlando, FL to Louisville, KY?

The earliest bus arriving in Louisville, KY from Orlando, FL starts at 6:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Orlando, FL to Louisville, KY?

The latest bus trip departing from Orlando, FL for Louisville, KY starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Orlando, FL Louisville, KY route?

When traveling by bus from Orlando, FL to Louisville, KY, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Orlando, FL and Louisville, KY?

You can check all the direct connections between Orlando, FL and Louisville, KY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Orlando, FL to Louisville, KY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Orlando, FL Louisville, KY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Orlando, FL Louisville, KY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Orlando, FL to Louisville, KY on your planned travel date.

Available seat classes which are offered on the bus route Orlando, FL to Louisville, KY

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Orlando, FL and to Louisville, KY

Here’s an overview of the most popular bus routes to Orlando, FL and to Louisville, KY. Simply click on the connection of your choice, and you will find all the details about your bus route!