Bus from Key West, FL to Orlando, FL from $45

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Compare all timetables for the bus from Key West, FL to Orlando, FL

Here is a selection of the cheapest bus trips from the schedule from Key West, FL to Orlando, FL from various bus operators like Greyhound US or FlixBus for the next days.
today
from $45
tomorrow
from $48
Thursday
from $47
Friday
from $51
Saturday
from $52
Sunday
from $51
Monday
from $46

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    11h 35m
    0
    10:00 AM
    Key West, FL
    Bus Stop
    9:35 PM
    Orlando, FL
    Florida Mall
    0
    Greyhound US
    Economy
    $45
  • Greyhound US
    10h 40m
    0
    5:00 PM
    Key West, FL
    Bus Stop
    3:40 AM
    Orlando, FL
    Florida Mall
    0
    Greyhound US
    Economy
    $45
  • Greyhound US
    10h 0m
    0
    10:00 AM
    Key West, FL
    Bus Stop
    8:00 PM
    Orlando, FL
    Bus Station
    0
    Greyhound US
    Economy
    $45
  • FlixBus
    14h 20m
    0
    1:20 PM
    Key West, FL
    Caroline St
    3:40 AM
    Orlando, FL
    Florida Mall
    0
    FlixBus
    Economy
    $45
  • FlixBus
    14h 55m
    0
    1:20 PM
    Key West, FL
    Caroline St
    4:15 AM
    Orlando, FL
    Bus Station
    0
    FlixBus
    Economy
    $46

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    11h 35m
    0
    10:00 AM
    Key West, FL
    Bus Stop
    9:35 PM
    Orlando, FL
    Florida Mall
    0
    Greyhound US
    Economy
    $48
  • Greyhound US
    10h 0m
    0
    10:00 AM
    Key West, FL
    Bus Stop
    8:00 PM
    Orlando, FL
    Bus Station
    0
    Greyhound US
    Economy
    $48
  • Greyhound US
    10h 40m
    0
    5:00 PM
    Key West, FL
    Bus Stop
    3:40 AM
    Orlando, FL
    Florida Mall
    0
    Greyhound US
    Economy
    $49
  • Greyhound US
    11h 15m
    0
    5:00 PM
    Key West, FL
    Bus Stop
    4:15 AM
    Orlando, FL
    Bus Station
    0
    Greyhound US
    Economy
    $49

Cheapest bus trips Thursday

Prices are for one way and one person
  • Greyhound US
    10h 40m
    0
    5:00 PM
    Key West, FL
    Bus Stop
    3:40 AM
    Orlando, FL
    Florida Mall
    0
    Greyhound US
    Economy
    $47
  • Greyhound US
    10h 0m
    0
    10:00 AM
    Key West, FL
    Bus Stop
    8:00 PM
    Orlando, FL
    Bus Station
    0
    Greyhound US
    Economy
    $47
  • FlixBus
    11h 4m
    0
    12:55 PM
    Key West, FL
    Bus Stop
    11:59 PM
    Orlando, FL
    Bus Station
    0
    FlixBus
    Economy
    $47
  • FlixBus
    14h 20m
    0
    1:20 PM
    Key West, FL
    Caroline St
    3:40 AM
    Orlando, FL
    Florida Mall
    0
    FlixBus
    Economy
    $47
  • FlixBus
    10h 39m
    0
    1:20 PM
    Key West, FL
    Caroline St
    11:59 PM
    Orlando, FL
    Bus Station
    0
    FlixBus
    Economy
    $47

Cheapest bus trips Friday

Prices are for one way and one person
  • Greyhound US
    10h 20m
    0
    10:00 AM
    Key West, FL
    Bus Stop
    8:20 PM
    Orlando, FL
    Florida Mall
    0
    Greyhound US
    Economy
    $51
  • Greyhound US
    10h 40m
    0
    5:00 PM
    Key West, FL
    Bus Stop
    3:40 AM
    Orlando, FL
    Florida Mall
    0
    Greyhound US
    Economy
    $51
  • Greyhound US
    11h 15m
    0
    5:00 PM
    Key West, FL
    Bus Stop
    4:15 AM
    Orlando, FL
    Bus Station
    0
    Greyhound US
    Economy
    $51
  • Greyhound US
    10h 0m
    0
    10:00 AM
    Key West, FL
    Bus Stop
    8:00 PM
    Orlando, FL
    Bus Station
    0
    Greyhound US
    Economy
    $52
  • Did you know that if you travel from Key West, FL to Orlando, FL via Miami Airport, you can save more than $7? You can find the corresponding connections below.
    • Busbud
      9h 55m
      0
      1:20 PM
      Key West, FL
      Caroline St
      5:15 PM
      Miami Airport
      Miami Airport - Terminal J
      0
      Busbud
      Economy
      $22
      • Waiting Time 0h 15m
    • Busbud
      5h 45m
      0
      5:30 PM
      Miami Airport
      Miami Airport - Regency Hotel
      11:15 PM
      Orlando, FL
      Jet Set Express Orlando Terminal
      0
      Busbud
      Economy
      $22
    Travel Time is 0h 5m shorter, and you will save $7

Cheapest bus trips Saturday

Prices are for one way and one person
  • Greyhound US
    10h 20m
    0
    10:00 AM
    Key West, FL
    Bus Stop
    8:20 PM
    Orlando, FL
    Florida Mall
    0
    Greyhound US
    Economy
    $52
  • Greyhound US
    10h 0m
    0
    10:00 AM
    Key West, FL
    Bus Stop
    8:00 PM
    Orlando, FL
    Bus Station
    0
    Greyhound US
    Economy
    $52
  • Greyhound US
    10h 40m
    0
    5:00 PM
    Key West, FL
    Bus Stop
    3:40 AM
    Orlando, FL
    Florida Mall
    0
    Greyhound US
    Economy
    $53
  • Greyhound US
    11h 15m
    0
    5:00 PM
    Key West, FL
    Bus Stop
    4:15 AM
    Orlando, FL
    Bus Station
    0
    Greyhound US
    Economy
    $53
  • Did you know that if you travel from Key West, FL to Orlando, FL via Miami Airport, you can save more than $8? You can find the corresponding connections below.
    • Busbud
      9h 55m
      0
      1:20 PM
      Key West, FL
      Caroline St
      5:15 PM
      Miami Airport
      Miami Airport - Terminal J
      0
      Busbud
      Economy
      $22
      • Waiting Time 0h 15m
    • Busbud
      5h 45m
      0
      5:30 PM
      Miami Airport
      Miami Airport - Regency Hotel
      11:15 PM
      Orlando, FL
      Jet Set Express Orlando Terminal
      0
      Busbud
      Economy
      $22
    Travel Time is 0h 5m shorter, and you will save $8

Cheapest bus trips Sunday

Prices are for one way and one person
  • Greyhound US
    10h 20m
    0
    10:00 AM
    Key West, FL
    Bus Stop
    8:20 PM
    Orlando, FL
    Florida Mall
    0
    Greyhound US
    Economy
    $51
  • Greyhound US
    10h 40m
    0
    5:00 PM
    Key West, FL
    Bus Stop
    3:40 AM
    Orlando, FL
    Florida Mall
    0
    Greyhound US
    Economy
    $51
  • Greyhound US
    11h 15m
    0
    5:00 PM
    Key West, FL
    Bus Stop
    4:15 AM
    Orlando, FL
    Bus Station
    0
    Greyhound US
    Economy
    $51
  • Greyhound US
    10h 0m
    0
    10:00 AM
    Key West, FL
    Bus Stop
    8:00 PM
    Orlando, FL
    Bus Station
    0
    Greyhound US
    Economy
    $52
  • Did you know that if you travel from Key West, FL to Orlando, FL via Miami Airport, you can save more than $7? You can find the corresponding connections below.
    • Busbud
      9h 55m
      0
      1:20 PM
      Key West, FL
      Caroline St
      5:15 PM
      Miami Airport
      Miami Airport - Terminal J
      0
      Busbud
      Economy
      $22
      • Waiting Time 0h 15m
    • Busbud
      5h 45m
      0
      5:30 PM
      Miami Airport
      Miami Airport - Regency Hotel
      11:15 PM
      Orlando, FL
      Jet Set Express Orlando Terminal
      0
      Busbud
      Economy
      $22
    Travel Time is 0h 5m shorter, and you will save $7

Cheapest bus trips Monday

Prices are for one way and one person
  • Greyhound US
    11h 35m
    0
    10:00 AM
    Key West, FL
    Bus Stop
    9:35 PM
    Orlando, FL
    Florida Mall
    0
    Greyhound US
    Economy
    $46
  • Greyhound US
    10h 40m
    0
    5:00 PM
    Key West, FL
    Bus Stop
    3:40 AM
    Orlando, FL
    Florida Mall
    0
    Greyhound US
    Economy
    $46
  • Greyhound US
    10h 0m
    0
    10:00 AM
    Key West, FL
    Bus Stop
    8:00 PM
    Orlando, FL
    Bus Station
    0
    Greyhound US
    Economy
    $46
  • FlixBus
    9h 35m
    0
    12:55 PM
    Key West, FL
    Bus Stop
    10:30 PM
    Orlando, FL
    Florida Mall
    0
    FlixBus
    Economy
    $46
  • FlixBus
    9h 30m
    0
    12:55 PM
    Key West, FL
    Bus Stop
    10:25 PM
    Orlando, FL
    Bus Station
    0
    FlixBus
    Economy
    $46

Frequency of bus connections between Key West, FL and Orlando, FL

See here how frequent the connections between Key West, FL and Orlando, FL are, during different times and days of the week.
Monday is the busiest day, with more than 20 daily buses from Key West, FL to Orlando, FL. Sunday has instead the fewest connections, with only 4 daily coaches between Key West, FL and Orlando, FL.
The busiest time of the day is the Afternoon, with 42 buses from Key West, FL to Orlando, FL, while Morning sees the fewest connections between Key West, FL and Orlando, FL, with 20 offers.

Facts about the bus from Key West, FL to Orlando, FL

Compare all providers like Greyhound US and FlixBus that travel 8 times every day by bus from Key West, FL to Orlando, FL in one click! Book your bus ticket from Key West, FL to Orlando, FL starting from $45!

Cheapest Bus $45
Fastest Bus 9h 5m
Earliest Bus 10:00 AM
Latest Bus 5:00 PM
Daily Bus Routes 8 Ø
Distance 276.6 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from Key West, FL to Orlando, FL

Every day, 8 buses from 2 bus companies leave Key West, FL for Orlando, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/13/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/11
Monday 05/12
Tuesday 05/13
$45
Wednesday 05/14
$48
Thursday 05/15
$47
Friday 05/16
$51
Saturday 05/17
$52
Sunday 05/18
$51
Monday 05/19
$46
Tuesday 05/20
Wednesday 05/21
$43
Thursday 05/22
Friday 05/23
$51
Saturday 05/24
Sunday 05/25
$69
Monday 05/26
Tuesday 05/27
$57
Wednesday 05/28
Thursday 05/29
$51
Friday 05/30
Saturday 05/31
Sunday 06/01
$73
Monday 06/02
Tuesday 06/03
Wednesday 06/04
Thursday 06/05
$40
Friday 06/06
Saturday 06/07

The cheapest time to travel from Key West, FL to Orlando, FL

See here on which day and which time of the day you can find the cheapest bus ticket from Key West, FL to Orlando, FL, for the next 30 days.
With a price starting from $45, Tuesday is the cheapest day for a bus from Key West, FL to Orlando, FL. Saturday instead is the most expensive day with prices starting from $52.
Afternoon is the cheapest day time for bus tickets from Key West, FL to Orlando, FL, with $45. Morning is the most expensive time of the day with prices starting from $45.

How to save money travelling from Key West, FL to Orlando, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Key West, FL to Orlando, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Key West, FL to Orlando, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Key West, FL to Orlando, FL are also emptier.

Beloved bus companies from Key West, FL to Orlando, FL

These are the most booked bus companies between Key West, FL to Orlando, FL from our users.

Greyhound US from Key West, FL to Orlando, FL

Greyhound US

Here you will find the key facts about the Greyhound US bus route Key West, FL to Orlando, FL:

Cheapest Price $45
Fastest Bus 10h 0m
Earliest Bus 10:00 AM
Last Bus 5:00 PM
Daily Connections 5 Ø
Found on 5/11/2025

All bus stations and stops in Key West, FL and Orlando, FL

In the map below, you can see where to find all bus stations in Key West, FL and Orlando, FL.

Service and Comfort on the bus from Key West, FL to Orlando, FL

Want to know which seat classes are available on the buses from Key West, FL to Orlando, FL? Or which bus companies serve the route Key West, FL to Orlando, FL? Below you will find answers to your questions.

FAQs about the Key West, FL to Orlando, FL bus

How much does a Key West, FL Orlando, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $45 and takes 10h 40m to reach Orlando, FL. Compare offers to save money!

How much could I save by comparing buses from Key West, FL to Orlando, FL?

This route is offered by 2 companies with a range of ticket prices between $45 and $53. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Orlando, FL.

On average, how many connections are available from Key West, FL to Orlando, FL each day?

Every day, the Key West, FL to Orlando, FL bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Key West, FL to Orlando, FL take?

The fastest bus from Key West, FL to Orlando, FL is offered by FlixBus and takes 9h 5m. Bus tickets for this connection cost $50. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Key West, FL to Orlando, FL?

The earliest bus arriving in Orlando, FL from Key West, FL starts at 10:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Key West, FL to Orlando, FL?

The latest bus trip departing from Key West, FL for Orlando, FL starts at 5:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Key West, FL Orlando, FL route?

When traveling by bus from Key West, FL to Orlando, FL, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Key West, FL and Orlando, FL?

You can check all the direct connections between Key West, FL and Orlando, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Key West, FL to Orlando, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Key West, FL Orlando, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Key West, FL Orlando, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Key West, FL to Orlando, FL on your planned travel date.

Available seat classes which are offered on the bus route Key West, FL to Orlando, FL

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Key West, FL and to Orlando, FL

Here’s an overview of the most popular bus routes to Key West, FL and to Orlando, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Miami - Key West, FL Buses Miami - Key West, FL
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West Palm Beach, FL to Key West, FL bus West Palm Beach, FL to Key West, FL bus
Buses Miami Beach, FL to Key West, FL Buses Miami Beach, FL to Key West, FL
Bus from Melbourne, FL to Orlando, FL Bus from Melbourne, FL to Orlando, FL
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Bus Fort Pierce, FL - Orlando, FL Bus Fort Pierce, FL - Orlando, FL
Bus Lakeland, FL - Orlando, FL Bus Lakeland, FL - Orlando, FL
Popular Airport Shuttles to Key West, FL and to Orlando, FL
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