Bus Chicago to Louisville, KY - Compare all Companies

Compare all timetables for the bus from Chicago to Louisville, KY

Here is a selection of the cheapest bus trips from the schedule from Chicago to Louisville, KY from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

Thursday

Friday

Saturday

$37

Sunday

$49

Monday

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	7h 5m	9:40 AM	Chicago	Downtown Bus Station	5:45 PM	Louisville, KY	Greyhound Bus Station	Economy	$37	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 3/28/2026 9:40:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 3/28/2026 5:45:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 5m
Greyhound US	6h 15m	2:45 PM	Chicago	Downtown Bus Station	10:00 PM	Louisville, KY	Greyhound Bus Station	Economy	$37	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 3/28/2026 2:45:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 3/28/2026 10:00:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 6h 15m
Greyhound US	7h 5m	10:50 PM	Chicago	Downtown Bus Station	6:55 AM	Louisville, KY	Greyhound Bus Station	Economy	$37	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 3/28/2026 10:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 3/29/2026 6:55:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 5m
FlixBus	6h 50m	5:25 AM	Chicago	95th Red Line Station	1:15 PM	Louisville, KY	Greyhound Bus Station	Economy	$39	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 3/28/2026 5:25:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 3/28/2026 1:15:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 6h 50m
FlixBus	11h 0m	5:45 AM	Chicago	95th Red Line Station	5:45 PM	Louisville, KY	Greyhound Bus Station	Economy	$39	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 3/28/2026 5:45:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 3/28/2026 5:45:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 11h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	6h 5m	6:10 AM	Chicago	Downtown Bus Station	1:15 PM	Louisville, KY	Greyhound Bus Station	Economy	$49	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 3/29/2026 6:10:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 3/29/2026 1:15:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 6h 5m
Greyhound US	7h 5m	9:40 AM	Chicago	Downtown Bus Station	5:45 PM	Louisville, KY	Greyhound Bus Station	Economy	$49	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 3/29/2026 9:40:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 3/29/2026 5:45:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 7h 5m
Greyhound US	6h 15m	2:45 PM	Chicago	Downtown Bus Station	10:00 PM	Louisville, KY	Greyhound Bus Station	Economy	$49	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 3/29/2026 2:45:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 3/29/2026 10:00:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 6h 15m
FlixBus	6h 25m	6:00 PM	Chicago	Downtown Bus Station	1:25 AM	Louisville, KY	Greyhound Bus Station	Economy	$53	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 3/29/2026 6:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 3/30/2026 1:25:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 6h 25m
FlixBus	7h 50m	1:00 PM	Chicago	Downtown Bus Station	9:50 PM	Louisville, KY	Greyhound Bus Station	Economy	$56	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 3/29/2026 1:00:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 3/29/2026 9:50:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 7h 50m

Best Price Offer: The price for the cheapest bus from Chicago to Louisville, KY is $34 on 4/15/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Chicago and Louisville, KY

See here how frequent the connections between Chicago and Louisville, KY are, during different times and days of the week.

Saturday is the busiest day, with more than 13 daily buses from Chicago to Louisville, KY. Sunday has instead the fewest connections, with only 8 daily coaches between Chicago and Louisville, KY.

The busiest time of the day is the Evening, with 8 buses from Chicago to Louisville, KY, while Night sees the fewest connections between Chicago and Louisville, KY, with 2 offers.

Facts about the bus from Chicago to Louisville, KY

Compare all providers like Greyhound US and FlixBus that travel 10 times every day by bus from Chicago to Louisville, KY in one click! Book your bus ticket from Chicago to Louisville, KY starting from $34!

Cheapest Bus	$34
Fastest Bus	6h 45m
Earliest Bus	5:25 AM
Latest Bus	11:10 PM
Daily Bus Routes	10 Ø
Distance	269.3 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Chicago to Louisville, KY

Every day, 10 buses from 2 bus companies leave Chicago for Louisville, KY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/24/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/22

Monday 03/23

Tuesday 03/24

Wednesday 03/25

Thursday 03/26

$39

Friday 03/27

Saturday 03/28

$37

Sunday 03/29

$49

Monday 03/30

Tuesday 03/31

$39

Wednesday 04/01

$44

Thursday 04/02

$38

Friday 04/03

Saturday 04/04

$42

Sunday 04/05

$44

Monday 04/06

$44

Tuesday 04/07

$37

Wednesday 04/08

$44

Thursday 04/09

$37

Friday 04/10

$41

Saturday 04/11

$37

Sunday 04/12

$41

Monday 04/13

$38

Tuesday 04/14

$41

Wednesday 04/15

$34

Thursday 04/16

$39

Friday 04/17

$37

Saturday 04/18

The cheapest time to travel from Chicago to Louisville, KY

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to Louisville, KY, for the next 30 days.

With a price starting from $36, Sunday is the cheapest day for a bus from Chicago to Louisville, KY. Saturday instead is the most expensive day with prices starting from $37.

Night is the cheapest day time for bus tickets from Chicago to Louisville, KY, with $34. Morning is the most expensive time of the day with prices starting from $37.

How to save money travelling from Chicago to Louisville, KY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to Louisville, KY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Louisville, KY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Louisville, KY are also emptier.

Beloved bus companies from Chicago to Louisville, KY

These are the most booked bus companies between Chicago to Louisville, KY from our users.

FlixBus from Chicago to Louisville, KY

Here you will find the key facts about the FlixBus bus route Chicago to Louisville, KY:

Cheapest Price	$39
Fastest Bus	6h 45m
Earliest Bus	5:25 AM
Last Bus	6:00 PM
Daily Connections	4 Ø
Found on	2/27/2026

Greyhound US from Chicago to Louisville, KY

Here you will find the key facts about the Greyhound US bus route Chicago to Louisville, KY:

Cheapest Price	$37
Fastest Bus	7h 5m
Earliest Bus	6:10 AM
Last Bus	11:10 PM
Daily Connections	6 Ø
Found on	2/27/2026

All bus stations and stops in Chicago and Louisville, KY

In the map below, you can see where to find all bus stations in Chicago and Louisville, KY.

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Greyhound Bus Station

W Muhammad Ali Blvd 720

Convention Center

S 3rd St 300

BP Gas Station

Newburg Rd 3301

W Muhammad Ali Blvd

East Broadway, under the I-65 overpass between S 1st Street and S Brook Street

International Airport

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Chicago to Louisville, KY? Compare all modes of transports from Chicago to Louisville, KY.

Service and Comfort on the bus from Chicago to Louisville, KY

Want to know which seat classes are available on the buses from Chicago to Louisville, KY? Or which bus companies serve the route Chicago to Louisville, KY? Below you will find answers to your questions.

FAQs about the Chicago to Louisville, KY bus

How much does a Chicago Louisville, KY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $34 and takes 8h 5m to reach Louisville, KY. Compare offers to save money!

How much could I save by comparing buses from Chicago to Louisville, KY?

This route is offered by 2 companies with a range of ticket prices between $34 and $56. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Louisville, KY.

On average, how many connections are available from Chicago to Louisville, KY each day?

Every day, the Chicago to Louisville, KY bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to Louisville, KY take?

The fastest bus from Chicago to Louisville, KY is offered by FlixBus and takes 6h 45m. Bus tickets for this connection cost $42. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to Louisville, KY?

The earliest bus arriving in Louisville, KY from Chicago starts at 5:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to Louisville, KY?

The latest bus trip departing from Chicago for Louisville, KY starts at 11:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago Louisville, KY route?

When traveling by bus from Chicago to Louisville, KY, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and Louisville, KY?

You can check all the direct connections between Chicago and Louisville, KY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to Louisville, KY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago Louisville, KY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago Louisville, KY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to Louisville, KY on your planned travel date.

How does CheckMyBus find the best bus deals from Chicago to Louisville, KY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between Chicago and Louisville, KY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Chicago to Louisville, KY?

Prices and availability for 10 trips between Chicago and Louisville, KY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Chicago to Louisville, KY

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to Louisville, KY

Here’s an overview of the most popular bus routes to Chicago and to Louisville, KY. Simply click on the connection of your choice, and you will find all the details about your bus route!