Bus Boston, MA to Louisville, KY - Compare all Companies

Compare all timetables for the bus from Boston, MA to Louisville, KY

Here is a selection of the cheapest bus trips from the schedule from Boston, MA to Louisville, KY from various bus operators like FlixBus or Greyhound US for the next days.

today

$189

tomorrow

Sunday

$199

Monday

Tuesday

$193

Wednesday

Thursday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	33h 50m	8:55 PM	Boston, MA	Allston	6:45 AM	Louisville, KY	Greyhound Bus Station	Economy	$189	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/19/2025 8:55:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/21/2025 6:45:00 AM. 50 Economy ticket for $189 per person are available. Travel duration is 33h 50m
FlixBus	38h 30m	9:50 PM	Boston, MA	South Station	12:20 PM	Louisville, KY	Greyhound Bus Station	Economy	$200	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 12/19/2025 9:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/21/2025 12:20:00 PM. 50 Economy ticket for $200 per person are available. Travel duration is 38h 30m
FlixBus	28h 45m	5:15 PM	Boston, MA	South Station	10:00 PM	Louisville, KY	Greyhound Bus Station	Economy	$267	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 12/19/2025 5:15:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/20/2025 10:00:00 PM. 50 Economy ticket for $267 per person are available. Travel duration is 28h 45m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	33h 50m	8:55 PM	Boston, MA	Allston	6:45 AM	Louisville, KY	Greyhound Bus Station	Economy	$199	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/21/2025 8:55:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/23/2025 6:45:00 AM. 50 Economy ticket for $199 per person are available. Travel duration is 33h 50m
FlixBus	29h 15m	1:30 AM	Boston, MA	Allston	6:45 AM	Louisville, KY	Greyhound Bus Station	Economy	$204	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/21/2025 1:30:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/22/2025 6:45:00 AM. 50 Economy ticket for $204 per person are available. Travel duration is 29h 15m
Greyhound US	28h 30m	2:15 AM	Boston, MA	South Station	6:45 AM	Louisville, KY	Greyhound Bus Station	Economy	$219	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/21/2025 2:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/22/2025 6:45:00 AM. 50 Economy ticket for $219 per person are available. Travel duration is 28h 30m
FlixBus	38h 30m	9:50 PM	Boston, MA	South Station	12:20 PM	Louisville, KY	Greyhound Bus Station	Economy	$231	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 12/21/2025 9:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/23/2025 12:20:00 PM. 50 Economy ticket for $231 per person are available. Travel duration is 38h 30m
Greyhound US	27h 5m	9:15 AM	Boston, MA	South Station	12:20 PM	Louisville, KY	Greyhound Bus Station	Economy	$235	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/21/2025 9:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/22/2025 12:20:00 PM. 50 Economy ticket for $235 per person are available. Travel duration is 27h 5m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	29h 15m	1:30 AM	Boston, MA	Allston	6:45 AM	Louisville, KY	Greyhound Bus Station	Economy	$193	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/23/2025 1:30:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/24/2025 6:45:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 29h 15m
FlixBus	38h 30m	9:50 PM	Boston, MA	South Station	12:20 PM	Louisville, KY	Greyhound Bus Station	Economy	$199	A Bus from FlixBus goes from South Station, Boston, MA (USA) at 12/23/2025 9:50:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/25/2025 12:20:00 PM. 50 Economy ticket for $199 per person are available. Travel duration is 38h 30m
Greyhound US	28h 30m	2:15 AM	Boston, MA	South Station	6:45 AM	Louisville, KY	Greyhound Bus Station	Economy	$218	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/23/2025 2:15:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/24/2025 6:45:00 AM. 50 Economy ticket for $218 per person are available. Travel duration is 28h 30m
FlixBus	33h 50m	8:55 PM	Boston, MA	Allston	6:45 AM	Louisville, KY	Greyhound Bus Station	Economy	$223	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/23/2025 8:55:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/25/2025 6:45:00 AM. 50 Economy ticket for $223 per person are available. Travel duration is 33h 50m
Greyhound US	27h 25m	8:55 AM	Boston, MA	South Station	12:20 PM	Louisville, KY	Greyhound Bus Station	Economy	$299	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/23/2025 8:55:00 AM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/24/2025 12:20:00 PM. 50 Economy ticket for $299 per person are available. Travel duration is 27h 25m

Did you know that if you travel from Boston, MA to Louisville, KY via New York, you can save more than $23? You can find the corresponding connections below.
- OurBus
  
  37h 0m
  
  0
  
  9:00 AM
  
  Boston, MA
  South Station Gate 12
  
  1:30 PM
  
  New York
  Port Authority Bus Terminal
  
  0
  
  Basic
  
  $19
  
  A Bus from OurBus goes from South Station Gate 12, Boston, MA (USA) at 12/24/2025 9:00:00 AM to Port Authority Bus Terminal, New York (USA) arriving at 12/24/2025 1:30:00 PM. 50 Basic ticket for $19 per person are available. Travel duration is 4h 30m
- Busbud
  
  23h 30m
  
  0
  
  10:30 PM
  
  New York
  Port Authority Bus Terminal
  
  10:00 PM
  
  Louisville, KY
  Greyhound Bus Station
  
  0
  
  Economy
  
  $151
  
  A Bus from Busbud goes from Port Authority Bus Terminal, New York (USA) at 12/24/2025 10:30:00 PM to Greyhound Bus Station, Louisville, KY (USA) arriving at 12/25/2025 10:00:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 23h 30m
Travel time is 9h 35m longer, but you will save $23

Best Price Offer: The price for the cheapest bus from Boston, MA to Louisville, KY is $119 on 12/15/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Boston, MA and Louisville, KY

See here how frequent the connections between Boston, MA and Louisville, KY are, during different times and days of the week.

Sunday is the busiest day, with more than 6 daily buses from Boston, MA to Louisville, KY. Friday has instead the fewest connections, with only 3 daily coaches between Boston, MA and Louisville, KY.

The busiest time of the day is the Evening, with 8 buses from Boston, MA to Louisville, KY, while Afternoon sees the fewest connections between Boston, MA and Louisville, KY, with 1 offers.

Facts about the bus from Boston, MA to Louisville, KY

Compare all providers like FlixBus and Greyhound US that travel 5 times every day by bus from Boston, MA to Louisville, KY in one click! Book your bus ticket from Boston, MA to Louisville, KY starting from $119!

Cheapest Bus	$119
Fastest Bus	27h 5m
Earliest Bus	5:15 PM
Latest Bus	9:50 PM
Daily Bus Routes	5 Ø
Distance	824.1 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Boston, MA to Louisville, KY

Every day, 5 buses from 2 bus companies leave Boston, MA for Louisville, KY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/19/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

$181

Saturday 12/20

Sunday 12/21

$199

Monday 12/22

Tuesday 12/23

$193

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Boston, MA to Louisville, KY

See here on which day and which time of the day you can find the cheapest bus ticket from Boston, MA to Louisville, KY, for the next 30 days.

With a price starting from $181, Friday is the cheapest day for a bus from Boston, MA to Louisville, KY. Sunday instead is the most expensive day with prices starting from $199.

Night is the cheapest day time for bus tickets from Boston, MA to Louisville, KY, with $181. Afternoon is the most expensive time of the day with prices starting from $265.

How to save money travelling from Boston, MA to Louisville, KY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Boston, MA to Louisville, KY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Boston, MA to Louisville, KY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Boston, MA to Louisville, KY are also emptier.

All bus stations and stops in Boston, MA and Louisville, KY

In the map below, you can see where to find all bus stations in Boston, MA and Louisville, KY.

South Station

Atlantic Ave 700

Prudential Center T Transit Station

Huntington Ave 220

Sheraton Hotel

Dalton St 39

South Station Gate 12

Atlantic Ave 700

Copley Square

Boylston Street

Convention Center

S 3rd St 300

BP Gas Station

Newburg Rd 3301

W Muhammad Ali Blvd

East Broadway, under the I-65 overpass between S 1st Street and S Brook Street

Greyhound Bus Station

W Muhammad Ali Blvd 720

International Airport

Service and Comfort on the bus from Boston, MA to Louisville, KY

Want to know which seat classes are available on the buses from Boston, MA to Louisville, KY? Or which bus companies serve the route Boston, MA to Louisville, KY? Below you will find answers to your questions.

FAQs about the Boston, MA to Louisville, KY bus

How much does a Boston, MA Louisville, KY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $119 and takes 33h 50m to reach Louisville, KY. Compare offers to save money!

How much could I save by comparing buses from Boston, MA to Louisville, KY?

This route is offered by 2 companies with a range of ticket prices between $119 and $314. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Louisville, KY.

On average, how many connections are available from Boston, MA to Louisville, KY each day?

Every day, the Boston, MA to Louisville, KY bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Boston, MA to Louisville, KY take?

The fastest bus from Boston, MA to Louisville, KY is offered by Greyhound US and takes 27h 5m. Bus tickets for this connection cost $235. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Boston, MA to Louisville, KY?

The earliest bus arriving in Louisville, KY from Boston, MA starts at 5:15 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Boston, MA to Louisville, KY?

The latest bus trip departing from Boston, MA for Louisville, KY starts at 9:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Boston, MA Louisville, KY route?

When traveling by bus from Boston, MA to Louisville, KY, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Boston, MA and Louisville, KY?

You can check all the direct connections between Boston, MA and Louisville, KY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Boston, MA to Louisville, KY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Boston, MA Louisville, KY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Boston, MA Louisville, KY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Boston, MA to Louisville, KY on your planned travel date.

How does CheckMyBus find the best bus deals from Boston, MA to Louisville, KY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Boston, MA and Louisville, KY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Boston, MA to Louisville, KY?

Prices and availability for 5 trips between Boston, MA and Louisville, KY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Boston, MA to Louisville, KY

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Boston, MA and to Louisville, KY

Here’s an overview of the most popular bus routes to Boston, MA and to Louisville, KY. Simply click on the connection of your choice, and you will find all the details about your bus route!