Bus Seattle, WA to Greenville, SC: Compare prices and save money

Compare all timetables for the bus from Seattle, WA to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Seattle, WA to Greenville, SC from various bus operators like Greyhound US for the next days.

today

$225

tomorrow

$224

Monday

Tuesday

Wednesday

Thursday

$224

Friday

$225

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	63h 55m	8:20 AM	Seattle, WA	Amtrak King Street Station	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$225	A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/20/2026 8:20:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 6/23/2026 3:15:00 AM. 50 Economy ticket for $225 per person are available. Travel duration is 63h 55m
Greyhound US	82h 5m	2:10 PM	Seattle, WA	Amtrak King Street Station	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$225	A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/20/2026 2:10:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 6/24/2026 3:15:00 AM. 50 Economy ticket for $225 per person are available. Travel duration is 82h 5m
Greyhound US	78h 45m	9:15 PM	Seattle, WA	Amtrak King Street Station	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$225	A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/20/2026 9:15:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 6/24/2026 7:00:00 AM. 50 Economy ticket for $225 per person are available. Travel duration is 78h 45m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	63h 55m	8:20 AM	Seattle, WA	Amtrak King Street Station	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$224	A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/21/2026 8:20:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 6/24/2026 3:15:00 AM. 50 Economy ticket for $224 per person are available. Travel duration is 63h 55m
Greyhound US	82h 5m	2:10 PM	Seattle, WA	Amtrak King Street Station	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$225	A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/21/2026 2:10:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 6/25/2026 3:15:00 AM. 50 Economy ticket for $225 per person are available. Travel duration is 82h 5m
Greyhound US	78h 45m	9:15 PM	Seattle, WA	Amtrak King Street Station	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$225	A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/21/2026 9:15:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 6/25/2026 7:00:00 AM. 50 Economy ticket for $225 per person are available. Travel duration is 78h 45m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	63h 55m	8:20 AM	Seattle, WA	Amtrak King Street Station	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$224	A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/25/2026 8:20:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 6/28/2026 3:15:00 AM. 50 Economy ticket for $224 per person are available. Travel duration is 63h 55m
Greyhound US	82h 5m	2:10 PM	Seattle, WA	Amtrak King Street Station	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$227	A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/25/2026 2:10:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 6/29/2026 3:15:00 AM. 50 Economy ticket for $227 per person are available. Travel duration is 82h 5m
Greyhound US	78h 45m	9:15 PM	Seattle, WA	Amtrak King Street Station	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$228	A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/25/2026 9:15:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 6/29/2026 7:00:00 AM. 50 Economy ticket for $228 per person are available. Travel duration is 78h 45m

Did you know that if you travel from Seattle, WA to Greenville, SC via Nashville, you can save more than $42? You can find the corresponding connections below.
- Greyhound US
  
  63h 55m
  
  0
  
  8:20 AM
  
  Seattle, WA
  Amtrak King Street Station
  
  3:40 PM
  
  Nashville
  5th Ave South Station
  
  0
  
  Economy
  
  $110
  
  A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/27/2026 8:20:00 AM to 5th Ave South Station, Nashville (USA) arriving at 6/29/2026 3:40:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 53h 20m
- Greyhound US
  
  8h 30m
  
  0
  
  5:45 PM
  
  Nashville
  5th Ave South Station
  
  3:15 AM
  
  Greenville, SC
  Woodruff Rd
  
  0
  
  Economy
  
  $71
  
  A Bus from Greyhound US goes from 5th Ave South Station, Nashville (USA) at 6/29/2026 5:45:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 6/30/2026 3:15:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 8h 30m
Travel Time is 3h 0m shorter, and you will save $42

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	82h 5m	2:10 PM	Seattle, WA	Amtrak King Street Station	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$225	A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/26/2026 2:10:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 6/30/2026 3:15:00 AM. 50 Economy ticket for $225 per person are available. Travel duration is 82h 5m
Greyhound US	63h 55m	8:20 AM	Seattle, WA	Amtrak King Street Station	3:15 AM	Greenville, SC	Woodruff Rd	Economy	$228	A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/26/2026 8:20:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 6/29/2026 3:15:00 AM. 50 Economy ticket for $228 per person are available. Travel duration is 63h 55m
Greyhound US	78h 45m	9:15 PM	Seattle, WA	Amtrak King Street Station	7:00 AM	Greenville, SC	Woodruff Rd	Economy	$233	A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/26/2026 9:15:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 6/30/2026 7:00:00 AM. 50 Economy ticket for $233 per person are available. Travel duration is 78h 45m

Did you know that if you travel from Seattle, WA to Greenville, SC via Nashville, you can save more than $46? You can find the corresponding connections below.
- Greyhound US
  
  67h 40m
  
  0
  
  8:20 AM
  
  Seattle, WA
  Amtrak King Street Station
  
  3:40 PM
  
  Nashville
  5th Ave South Station
  
  0
  
  Economy
  
  $110
  
  A Bus from Greyhound US goes from Amtrak King Street Station, Seattle, WA (USA) at 6/27/2026 8:20:00 AM to 5th Ave South Station, Nashville (USA) arriving at 6/29/2026 3:40:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 53h 20m
- Greyhound US
  
  8h 0m
  
  0
  
  10:00 PM
  
  Nashville
  5th Ave South Station
  
  7:00 AM
  
  Greenville, SC
  Woodruff Rd
  
  0
  
  Economy
  
  $68
  
  A Bus from Greyhound US goes from 5th Ave South Station, Nashville (USA) at 6/29/2026 10:00:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 6/30/2026 7:00:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 0m
Travel time is 0h 45m longer, but you will save $46

Best Price Offer: The price for the cheapest bus from Seattle, WA to Greenville, SC is $224 on 7/10/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Seattle, WA and Greenville, SC

See here how frequent the connections between Seattle, WA and Greenville, SC are, during different times and days of the week.

Sunday is the busiest day, with more than 3 daily buses from Seattle, WA to Greenville, SC. Sunday has instead the fewest connections, with only 3 daily coaches between Seattle, WA and Greenville, SC.

The busiest time of the day is the Morning, with 4 buses from Seattle, WA to Greenville, SC, while Morning sees the fewest connections between Seattle, WA and Greenville, SC, with 4 offers.

Facts about the bus from Seattle, WA to Greenville, SC

Compare all providers like Greyhound US that travel 3 times every day by bus from Seattle, WA to Greenville, SC in one click! Book your bus ticket from Seattle, WA to Greenville, SC starting from $224!

Cheapest Bus	$224
Fastest Bus	66h 55m
Earliest Bus	8:20 AM
Latest Bus	9:15 PM
Daily Bus Routes	3 Ø
Distance	2,223.0 miles
Bus Companies	Greyhound US

Cheapest bus connections from Seattle, WA to Greenville, SC

Every day, 3 buses from 1 bus companies leave Seattle, WA for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/14

Monday 06/15

Tuesday 06/16

Wednesday 06/17

Thursday 06/18

Friday 06/19

Saturday 06/20

$225

Sunday 06/21

$224

Monday 06/22

Tuesday 06/23

Wednesday 06/24

Thursday 06/25

$224

Friday 06/26

$225

Saturday 06/27

Sunday 06/28

$225

Monday 06/29

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

Friday 07/03

Saturday 07/04

Sunday 07/05

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

Friday 07/10

$224

Saturday 07/11

The cheapest time to travel from Seattle, WA to Greenville, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Seattle, WA to Greenville, SC, for the next 30 days.

With a price starting from $224, Friday is the cheapest day for a bus from Seattle, WA to Greenville, SC. Saturday instead is the most expensive day with prices starting from $225.

Morning is the cheapest day time for bus tickets from Seattle, WA to Greenville, SC, with $224. Evening is the most expensive time of the day with prices starting from $225.

How to save money travelling from Seattle, WA to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Seattle, WA to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Seattle, WA to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Seattle, WA to Greenville, SC are also emptier.

All bus stations and stops in Seattle, WA and Greenville, SC

In the map below, you can see where to find all bus stations in Seattle, WA and Greenville, SC.

Amtrak King Street Station

S Jackson St 303

Veterans Administration Hospital

S Columbian Way 1660

Convention Center

8th Ave 1500

Stadium

Harborview Medical Center

8th Ave 325

Woodruff Rd

Woodruff Rd 1116

N Church St

Greyhound Bus Station

Hendrix Dr 9

Guadalajara Supermarket

White Horse Rd 2803

McDonald's

Woodruff Rd 1111

Service and Comfort on the bus from Seattle, WA to Greenville, SC

Want to know which seat classes are available on the buses from Seattle, WA to Greenville, SC? Or which bus companies serve the route Seattle, WA to Greenville, SC? Below you will find answers to your questions.

FAQs about the Seattle, WA to Greenville, SC bus

How much does a Seattle, WA Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $224 and takes 66h 55m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Seattle, WA to Greenville, SC?

This route is offered by 1 companies with a range of ticket prices between $224 and $233. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Seattle, WA to Greenville, SC each day?

Every day, the Seattle, WA to Greenville, SC bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Seattle, WA to Greenville, SC take?

The fastest bus from Seattle, WA to Greenville, SC is offered by Greyhound US and takes 66h 55m. Bus tickets for this connection cost $225. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Seattle, WA to Greenville, SC?

The earliest bus arriving in Greenville, SC from Seattle, WA starts at 8:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Seattle, WA to Greenville, SC?

The latest bus trip departing from Seattle, WA for Greenville, SC starts at 9:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Seattle, WA Greenville, SC route?

When traveling by bus from Seattle, WA to Greenville, SC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Seattle, WA and Greenville, SC?

You can check all the direct connections between Seattle, WA and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Seattle, WA to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Seattle, WA Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Seattle, WA Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Seattle, WA to Greenville, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Seattle, WA to Greenville, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Seattle, WA and Greenville, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Seattle, WA to Greenville, SC?

Prices and availability for 3 trips between Seattle, WA and Greenville, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Seattle, WA to Greenville, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Seattle, WA and to Greenville, SC

Here’s an overview of the most popular bus routes to Seattle, WA and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!