Compare all timetables for the bus from Wilmington, DE to Greenville, SC
Here is a selection of the cheapest bus trips from the schedule from Wilmington, DE to Greenville, SC from various bus operators like Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 18h 45m | 1:50 PM | Wilmington, DE | Greyhound | 8:35 AM | Greenville, SC | Woodruff Rd | Economy | $80 |
A Bus from Greyhound US goes from Greyhound, Wilmington, DE (USA) at 5/19/2026 1:50:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/20/2026 8:35:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 18h 45m
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| Greyhound US | 15h 50m | 9:25 PM | Wilmington, DE | Greyhound | 1:15 PM | Greenville, SC | Woodruff Rd | Economy | $80 |
A Bus from Greyhound US goes from Greyhound, Wilmington, DE (USA) at 5/19/2026 9:25:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/20/2026 1:15:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 15h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 18h 45m | 1:50 PM | Wilmington, DE | Greyhound | 8:35 AM | Greenville, SC | Woodruff Rd | Economy | $88 |
A Bus from Greyhound US goes from Greyhound, Wilmington, DE (USA) at 5/21/2026 1:50:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/22/2026 8:35:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 18h 45m
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| Greyhound US | 15h 50m | 9:25 PM | Wilmington, DE | Greyhound | 1:15 PM | Greenville, SC | Woodruff Rd | Economy | $88 |
A Bus from Greyhound US goes from Greyhound, Wilmington, DE (USA) at 5/21/2026 9:25:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/22/2026 1:15:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 15h 50m
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Did you know that if you travel from Wilmington, DE to Greenville, SC via Washington, DC, you can save more than $9? You can find the corresponding connections below.
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Greyhound US18h 55m01:40 PMWilmington, DEGreyhound4:30 PMWashington, DCUnion Station0EconomyA Bus from Greyhound US goes from Greyhound, Wilmington, DE (USA) at 5/20/2026 1:40:00 PM to Union Station, Washington, DC (USA) arriving at 5/20/2026 4:30:00 PM. 50 Economy ticket for $18 per person are available. Travel duration is 2h 50m
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FlixBus9h 50m010:45 PMWashington, DCUnion Station8:35 AMGreenville, SCWoodruff Rd0EconomyA Bus from FlixBus goes from Union Station, Washington, DC (USA) at 5/20/2026 10:45:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/21/2026 8:35:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 9h 50m
Waiting Time 6h 15mTravel time is 3h 5m longer, but you will save $9 -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 18h 45m | 1:50 PM | Wilmington, DE | Greyhound | 8:35 AM | Greenville, SC | Woodruff Rd | Economy | $78 |
A Bus from Greyhound US goes from Greyhound, Wilmington, DE (USA) at 5/24/2026 1:50:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/25/2026 8:35:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 18h 45m
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| Greyhound US | 15h 50m | 9:25 PM | Wilmington, DE | Greyhound | 1:15 PM | Greenville, SC | Woodruff Rd | Economy | $78 |
A Bus from Greyhound US goes from Greyhound, Wilmington, DE (USA) at 5/24/2026 9:25:00 PM to Woodruff Rd, Greenville, SC (USA) arriving at 5/25/2026 1:15:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 15h 50m
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Best Price Offer: The price for the cheapest bus from Wilmington, DE to Greenville, SC is $70 on 6/1/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Wilmington, DE and Greenville, SC
Sunday
is the busiest day, with more than 2 daily buses from Wilmington, DE to Greenville, SC. Sunday has instead the fewest connections, with only 2 daily coaches between Wilmington, DE and Greenville, SC.
The busiest time of the day is the Afternoon, with 3 buses from Wilmington, DE to Greenville, SC, while Afternoon sees the fewest connections between Wilmington, DE and Greenville, SC, with 3 offers.
Facts about the bus from Wilmington, DE to Greenville, SC
Compare all providers like Greyhound US that travel 2 times every day by bus from Wilmington, DE to Greenville, SC in one click! Book your bus ticket from Wilmington, DE to Greenville, SC starting from $70!
| Cheapest Bus | $70 |
| Fastest Bus | 15h 50m |
| Earliest Bus | 1:50 PM |
| Latest Bus | 9:25 PM |
| Daily Bus Routes | 2 Ø |
| Distance | 505.8 miles |
| Bus Companies | Greyhound US |
Cheapest bus connections from Wilmington, DE to Greenville, SC
Every day, 2 buses from 1 bus companies leave Wilmington, DE for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/19/2026 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
05/17
Monday
05/18
Tuesday
05/19
$80
Wednesday
05/20
Thursday
05/21
$130
Friday
05/22
Saturday
05/23
Sunday
05/24
$77
Monday
05/25
Tuesday
05/26
$76
Wednesday
05/27
$78
Thursday
05/28
$76
Friday
05/29
$129
Saturday
05/30
$130
Sunday
05/31
$75
Monday
06/01
$70
Tuesday
06/02
$70
Wednesday
06/03
$130
Thursday
06/04
Friday
06/05
Saturday
06/06
$130
Sunday
06/07
$132
Monday
06/08
$130
Tuesday
06/09
$75
Wednesday
06/10
$130
Thursday
06/11
$130
Friday
06/12
Saturday
06/13
The cheapest time to travel from Wilmington, DE to Greenville, SC
With a price starting from $70, Tuesday is the cheapest day for a bus from Wilmington, DE to Greenville, SC. Thursday instead is the most expensive day with prices starting from $76.
Afternoon
is the cheapest day time for bus tickets from Wilmington, DE to Greenville, SC, with $78. Evening is the most expensive time of the day with prices starting from $78.
How to save money travelling from Wilmington, DE to Greenville, SC
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Wilmington, DE to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Wilmington, DE to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Wilmington, DE to Greenville, SC are also emptier.All bus stations and stops in Wilmington, DE and Greenville, SC
In the map below, you can see where to find all bus stations in Wilmington, DE and Greenville, SC.
Service and Comfort on the bus from Wilmington, DE to Greenville, SC
Want to know which seat classes are available on the buses from Wilmington, DE to Greenville, SC? Or which bus companies serve the route Wilmington, DE to Greenville, SC? Below you will find answers to your questions.
FAQs about the Wilmington, DE to Greenville, SC bus
How much does a Wilmington, DE Greenville, SC bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $70 and takes 18h 45m to reach Greenville, SC. Compare offers to save money!
How much could I save by comparing buses from Wilmington, DE to Greenville, SC?
This route is offered by 1 companies with a range of ticket prices between $70 and $88. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.
On average, how many connections are available from Wilmington, DE to Greenville, SC each day?
Every day, the Wilmington, DE to Greenville, SC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Wilmington, DE to Greenville, SC take?
The fastest bus from Wilmington, DE to Greenville, SC is offered by Greyhound US and takes 15h 50m. Bus tickets for this connection cost $80. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Wilmington, DE to Greenville, SC?
The earliest bus arriving in Greenville, SC from Wilmington, DE starts at 1:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Wilmington, DE to Greenville, SC?
The latest bus trip departing from Wilmington, DE for Greenville, SC starts at 9:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Wilmington, DE Greenville, SC route?
When traveling by bus from Wilmington, DE to Greenville, SC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Wilmington, DE and Greenville, SC?
You can check all the direct connections between Wilmington, DE and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.
What can I take with me on the Wilmington, DE to Greenville, SC bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Wilmington, DE Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Wilmington, DE Greenville, SC bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Wilmington, DE to Greenville, SC on your planned travel date.
How does CheckMyBus find the best bus deals from Wilmington, DE to Greenville, SC?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Wilmington, DE and Greenville, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Wilmington, DE to Greenville, SC?
Prices and availability for 2 trips between Wilmington, DE and Greenville, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Wilmington, DE to Greenville, SC
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Wilmington, DE and to Greenville, SC
Here’s an overview of the most popular bus routes to Wilmington, DE and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Wilmington, DE
- Buses from Atlanta, GA to Wilmington, DE
- Buses to Wilmington, DE from Baltimore, MD
- Buses from Buffalo, NY to Wilmington, DE
- Bus from College Park, MD to Wilmington, DE
- Bus Durham, NC - Wilmington, DE
- Buses to Wilmington, DE from Flint, MI
- Buses to Wilmington, DE from Greensboro, NC
- Hampton, VA to Wilmington, DE bus
- Bus from Jacksonville, NC to Wilmington, DE
- Bus New Carrollton, MD to Wilmington, DE
- Buses from Newark to Wilmington, DE
- From Norfolk, VA to Wilmington, DE bus
- Buses to Wilmington, DE from Providence, RI
- Bus to Wilmington, DE from Queens Village, NY
- Buses Rochester, NY - Wilmington, DE
- Bus Salisbury, MD - Wilmington, DE
- Buses Syracuse, NY - Wilmington, DE
- Bus Tallahassee, FL - Wilmington, DE
- Bus Routes to Greenville, SC
- Bus from Austin to Greenville, SC
- Buses from Baltimore, MD to Greenville, SC
- Bus to Greenville, SC from Birmingham, AL
- Buses from Charleston, SC to Greenville, SC
- Buses Detroit - Greenville, SC
- From Doraville, GA to Greenville, SC bus
- Buses from Durham, NC to Greenville, SC
- Bus Fort Myers, FL to Greenville, SC
- Buses Gainesville, FL to Greenville, SC
- Indianapolis to Greenville, SC bus
- Miami to Greenville, SC bus
- Bus from Myrtle Beach, SC to Greenville, SC
- From Nashville to Greenville, SC bus
- Bus New York to Greenville, SC
- Buses to Greenville, SC from Norcross, GA
- North Charleston, SC to Greenville, SC bus
- Bus to Greenville, SC from Philadelphia
- Bus from South Bend, IN to Greenville, SC
- Bus Tampa to Greenville, SC
- Buses Terre Haute, IN - Greenville, SC
Popular Airport Shuttles to Wilmington, DE and to Greenville, SC
