Which bus from San Antonio, TX to St. Louis, MO is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $104
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Compare all timetables for the bus from San Antonio, TX to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to St. Louis, MO from various bus operators like FlixBus, Greyhound Lines Mexico or Greyhound US for the next days.

today
$183
tomorrow
$104
Tuesday
$171
Wednesday
$162
Thursday
Friday
$180
Saturday
$181

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 25h 30m 9:15 PM San Antonio, TX Bus Station 10:45 PM St. Louis, MO Gateway Station  Economy $183
Greyhound Lines Mexico 21h 15m 1:30 AM San Antonio, TX Bus Station 10:45 PM St. Louis, MO Gateway Station  Economy $185
Greyhound US 24h 20m 12:35 PM San Antonio, TX Bus Station 12:55 PM St. Louis, MO Gateway Station  Economy $186
FlixBus 23h 40m 7:30 AM San Antonio, TX Bus Station 7:10 AM St. Louis, MO Gateway Station  Economy $187

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound Lines Mexico 27h 30m 7:15 PM San Antonio, TX Bus Station 10:45 PM St. Louis, MO Gateway Station  Economy $104
Greyhound Lines Mexico 25h 20m 5:50 AM San Antonio, TX Bus Station 7:10 AM St. Louis, MO Gateway Station  Economy $104
Greyhound US 24h 20m 12:35 PM San Antonio, TX Bus Station 12:55 PM St. Louis, MO Gateway Station  Economy $106
FlixBus 23h 40m 7:30 AM San Antonio, TX Bus Station 7:10 AM St. Louis, MO Gateway Station  Economy $124
FlixBus 23h 25m 7:45 AM San Antonio, TX Pearl District 7:10 AM St. Louis, MO Gateway Station  Economy $124

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 24h 20m 12:35 PM San Antonio, TX Bus Station 12:55 PM St. Louis, MO Gateway Station  Economy $171
Greyhound Lines Mexico 27h 30m 7:15 PM San Antonio, TX Bus Station 10:45 PM St. Louis, MO Gateway Station  Economy $172
Greyhound Lines Mexico 21h 15m 1:30 AM San Antonio, TX Bus Station 10:45 PM St. Louis, MO Gateway Station  Economy $175
  • Did you know that if you travel from San Antonio, TX to St. Louis, MO via Dallas, you can save more than $49? You can find the corresponding connections below.
    • Busbud
      29h 30m
      0
      5:20 PM
      San Antonio, TX
      Pearl District
      11:05 PM
      Dallas
      Downtown
      0
      Busbud
      Economy
      $34
    • Waiting Time 7h 55m
    • FlixBus
      15h 50m
      0
      7:00 AM
      Dallas
      Bus Station
      10:50 PM
      St. Louis, MO
      Gateway Station
      0
      FlixBus
      Economy
      $88
    Travel time is 8h 15m longer, but you will save $49

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 24h 20m 12:35 PM San Antonio, TX Bus Station 12:55 PM St. Louis, MO Gateway Station  Economy $162
Greyhound Lines Mexico 21h 15m 1:30 AM San Antonio, TX Bus Station 10:45 PM St. Louis, MO Gateway Station  Economy $163
FlixBus 25h 30m 9:15 PM San Antonio, TX Bus Station 10:45 PM St. Louis, MO Gateway Station  Economy $163
  • Did you know that if you travel from San Antonio, TX to St. Louis, MO via Dallas, you can save more than $40? You can find the corresponding connections below.
    • Busbud
      29h 30m
      0
      5:20 PM
      San Antonio, TX
      Pearl District
      11:05 PM
      Dallas
      Downtown
      0
      Busbud
      Economy
      $34
    • Waiting Time 7h 55m
    • FlixBus
      15h 50m
      0
      7:00 AM
      Dallas
      Bus Station
      10:50 PM
      St. Louis, MO
      Gateway Station
      0
      FlixBus
      Economy
      $88
    Travel time is 8h 15m longer, but you will save $40

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 40m 7:30 AM San Antonio, TX Bus Station 7:10 AM St. Louis, MO Gateway Station  Economy $180
FlixBus 25h 30m 9:15 PM San Antonio, TX Bus Station 10:45 PM St. Louis, MO Gateway Station  Economy $180
Greyhound US 24h 20m 12:35 PM San Antonio, TX Bus Station 12:55 PM St. Louis, MO Gateway Station  Economy $180
Greyhound Lines Mexico 21h 15m 1:30 AM San Antonio, TX Bus Station 10:45 PM St. Louis, MO Gateway Station  Economy $182
  • Did you know that if you travel from San Antonio, TX to St. Louis, MO via Dallas, you can save more than $58? You can find the corresponding connections below.
    • Busbud
      29h 30m
      0
      5:20 PM
      San Antonio, TX
      Pearl District
      11:05 PM
      Dallas
      Downtown
      0
      Busbud
      Economy
      $34
    • Waiting Time 7h 55m
    • FlixBus
      15h 50m
      0
      7:00 AM
      Dallas
      Bus Station
      10:50 PM
      St. Louis, MO
      Gateway Station
      0
      FlixBus
      Economy
      $88
    Travel time is 8h 15m longer, but you will save $58

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 24h 20m 12:35 PM San Antonio, TX Bus Station 12:55 PM St. Louis, MO Gateway Station  Economy $181
Greyhound Lines Mexico 21h 15m 1:30 AM San Antonio, TX Bus Station 10:45 PM St. Louis, MO Gateway Station  Economy $182
FlixBus 23h 40m 7:30 AM San Antonio, TX Bus Station 7:10 AM St. Louis, MO Gateway Station  Economy $182
FlixBus 25h 30m 9:15 PM San Antonio, TX Bus Station 10:45 PM St. Louis, MO Gateway Station  Economy $182
  • Did you know that if you travel from San Antonio, TX to St. Louis, MO via Dallas, you can save more than $59? You can find the corresponding connections below.
    • Busbud
      29h 30m
      0
      5:20 PM
      San Antonio, TX
      Pearl District
      11:05 PM
      Dallas
      Downtown
      0
      Busbud
      Economy
      $34
    • Waiting Time 7h 55m
    • FlixBus
      15h 50m
      0
      7:00 AM
      Dallas
      Bus Station
      10:50 PM
      St. Louis, MO
      Gateway Station
      0
      FlixBus
      Economy
      $88
    Travel time is 8h 15m longer, but you will save $59

Best Price Offer: The price for the cheapest bus from San Antonio, TX to St. Louis, MO is $104 on 2/9/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between San Antonio, TX and St. Louis, MO

See here how frequent the connections between San Antonio, TX and St. Louis, MO are, during different times and days of the week.
Monday is the busiest day, with more than 9 daily buses from San Antonio, TX to St. Louis, MO. Tuesday has instead the fewest connections, with only 3 daily coaches between San Antonio, TX and St. Louis, MO.
The busiest time of the day is the Morning, with 8 buses from San Antonio, TX to St. Louis, MO, while Afternoon sees the fewest connections between San Antonio, TX and St. Louis, MO, with 7 offers.

Facts about the bus from San Antonio, TX to St. Louis, MO

Compare all providers like FlixBus, Greyhound Lines Mexico and Greyhound US that travel 5 times every day by bus from San Antonio, TX to St. Louis, MO in one click! Book your bus ticket from San Antonio, TX to St. Louis, MO starting from $104!

Cheapest Bus $104
Fastest Bus 21h 15m
Earliest Bus 1:30 AM
Latest Bus 9:15 PM
Daily Bus Routes 5 Ø
Distance 792.3 miles
Bus Companies FlixBus, Greyhound Lines Mexico and Greyhound US

Cheapest bus connections from San Antonio, TX to St. Louis, MO

Every day, 5 buses from 3 bus companies leave San Antonio, TX for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/08/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/08
$183
Monday 02/09
$104
Tuesday 02/10
$171
Wednesday 02/11
$162
Thursday 02/12
Friday 02/13
$180
Saturday 02/14
$181
Sunday 02/15
Monday 02/16
Tuesday 02/17
Wednesday 02/18
Thursday 02/19
Friday 02/20
Saturday 02/21
Sunday 02/22
Monday 02/23
Tuesday 02/24
Wednesday 02/25
Thursday 02/26
Friday 02/27
Saturday 02/28
Sunday 03/01
$137
Monday 03/02
Tuesday 03/03
Wednesday 03/04
Thursday 03/05
Friday 03/06
Saturday 03/07

The cheapest time to travel from San Antonio, TX to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to St. Louis, MO, for the next 30 days.
With a price starting from $104, Monday is the cheapest day for a bus from San Antonio, TX to St. Louis, MO. Saturday instead is the most expensive day with prices starting from $181.
Night is the cheapest day time for bus tickets from San Antonio, TX to St. Louis, MO, with $104. Morning is the most expensive time of the day with prices starting from $124.

How to save money travelling from San Antonio, TX to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to St. Louis, MO are also emptier.

Beloved bus companies from San Antonio, TX to St. Louis, MO

These are the most booked bus companies between San Antonio, TX to St. Louis, MO from our users.

All bus stations and stops in San Antonio, TX and St. Louis, MO

In the map below, you can see where to find all bus stations in San Antonio, TX and St. Louis, MO.

Service and Comfort on the bus from San Antonio, TX to St. Louis, MO

Want to know which seat classes are available on the buses from San Antonio, TX to St. Louis, MO? Or which bus companies serve the route San Antonio, TX to St. Louis, MO? Below you will find answers to your questions.

FAQs about the San Antonio, TX to St. Louis, MO bus

How much does a San Antonio, TX St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $104 and takes 25h 20m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to St. Louis, MO?

This route is offered by 3 companies with a range of ticket prices between $104 and $187. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from San Antonio, TX to St. Louis, MO each day?

Every day, the San Antonio, TX to St. Louis, MO bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to St. Louis, MO take?

The fastest bus from San Antonio, TX to St. Louis, MO is offered by Greyhound Lines Mexico and takes 21h 15m. Bus tickets for this connection cost $185. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from San Antonio, TX starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to St. Louis, MO?

The latest bus trip departing from San Antonio, TX for St. Louis, MO starts at 9:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX St. Louis, MO route?

When traveling by bus from San Antonio, TX to St. Louis, MO, passengers can travel with FlixBus, Greyhound Lines Mexico and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and St. Louis, MO?

You can check all the direct connections between San Antonio, TX and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound Lines Mexico and Greyhound US.

What can I take with me on the San Antonio, TX to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from San Antonio, TX to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between San Antonio, TX and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Antonio, TX to St. Louis, MO?

Prices and availability for 5 trips between San Antonio, TX and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Antonio, TX to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to St. Louis, MO

Here’s an overview of the most popular bus routes to San Antonio, TX and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!

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