Bus from San Antonio, TX to St. Louis, MO from $117

Compare 3 companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from San Antonio, TX to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to St. Louis, MO from various bus operators like FlixBus, Greyhound Lines Mexico or Greyhound US for the next days.
today
tomorrow
from $117
Saturday
from $128
Sunday
Monday
from $147
Tuesday
from $165
Wednesday

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    23h 35m
    0
    7:30 AM
    San Antonio, TX
    Bus Station
    7:05 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $117
  • FlixBus
    25h 40m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $117
  • Greyhound Lines Mexico
    20h 40m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $145
  • Greyhound Lines Mexico
    21h 10m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $146
  • Greyhound US
    24h 15m
    0
    12:40 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $152

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    25h 40m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $128
  • FlixBus
    23h 35m
    0
    7:30 AM
    San Antonio, TX
    Bus Station
    7:05 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $136
  • Greyhound US
    24h 15m
    0
    12:40 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $150
  • Greyhound Lines Mexico
    21h 10m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $151

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    23h 35m
    0
    7:30 AM
    San Antonio, TX
    Bus Station
    7:05 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $147
  • FlixBus
    23h 20m
    0
    7:45 AM
    San Antonio, TX
    Pearl District
    7:05 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $147
  • Greyhound Lines Mexico
    27h 25m
    0
    7:15 PM
    San Antonio, TX
    Bus Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $158
  • Greyhound Lines Mexico
    21h 10m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $163
  • Greyhound US
    24h 15m
    0
    12:40 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $177
  • Did you know that if you travel from San Antonio, TX to St. Louis, MO via Dallas, you can save more than $35? You can find the corresponding connections below.
    • FlixBus
      28h 30m
      0
      6:20 PM
      San Antonio, TX
      Bus Station
      11:20 PM
      Dallas
      Bus Station
      0
      FlixBus
      Economy
      $36
      • Waiting Time 7h 40m
    • FlixBus
      15h 50m
      0
      7:00 AM
      Dallas
      Bus Station
      10:50 PM
      St. Louis, MO
      Gateway Station
      0
      FlixBus
      Economy
      $76
    Travel time is 7h 20m longer, but you will save $35

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound Lines Mexico
    27h 25m
    0
    7:15 PM
    San Antonio, TX
    Bus Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $165
  • Greyhound Lines Mexico
    21h 10m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $174
  • Greyhound US
    24h 15m
    0
    12:40 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $179
  • Did you know that if you travel from San Antonio, TX to St. Louis, MO via Dallas, you can save more than $54? You can find the corresponding connections below.
    • FlixBus
      21h 20m
      0
      1:30 AM
      San Antonio, TX
      Bus Station
      6:25 AM
      Dallas
      Bus Station
      0
      FlixBus
      Economy
      $37
      • Waiting Time 0h 35m
    • Busbud
      15h 50m
      0
      7:00 AM
      Dallas
      Bus Station
      10:50 PM
      St. Louis, MO
      Gateway Station
      0
      Busbud
      Economy
      $74
    Travel time is 0h 10m longer, but you will save $54

Frequency of bus connections between San Antonio, TX and St. Louis, MO

See here how frequent the connections between San Antonio, TX and St. Louis, MO are, during different times and days of the week.
Friday is the busiest day, with more than 8 daily buses from San Antonio, TX to St. Louis, MO. Tuesday has instead the fewest connections, with only 3 daily coaches between San Antonio, TX and St. Louis, MO.
The busiest time of the day is the Morning, with 6 buses from San Antonio, TX to St. Louis, MO, while Evening sees the fewest connections between San Antonio, TX and St. Louis, MO, with 4 offers.

Facts about the bus from San Antonio, TX to St. Louis, MO

Compare all providers like FlixBus, Greyhound Lines Mexico and Greyhound US that travel 5 times every day by bus from San Antonio, TX to St. Louis, MO in one click! Book your bus ticket from San Antonio, TX to St. Louis, MO starting from $117!

Cheapest Bus $117
Fastest Bus 20h 40m
Earliest Bus 1:30 AM
Latest Bus 7:15 PM
Daily Bus Routes 5 Ø
Distance 792.3 miles
Bus Companies FlixBus, Greyhound Lines Mexico and Greyhound US

Cheapest bus connections from San Antonio, TX to St. Louis, MO

Every day, 5 buses from 3 bus companies leave San Antonio, TX for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/19/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/15
Monday 06/16
Tuesday 06/17
Wednesday 06/18
Thursday 06/19
Friday 06/20
$117
Saturday 06/21
$128
Sunday 06/22
Monday 06/23
$147
Tuesday 06/24
$165
Wednesday 06/25
Thursday 06/26
$152
Friday 06/27
Saturday 06/28
Sunday 06/29
Monday 06/30
$140
Tuesday 07/01
Wednesday 07/02
Thursday 07/03
$189
Friday 07/04
Saturday 07/05
$123
Sunday 07/06
$94
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
Saturday 07/12

The cheapest time to travel from San Antonio, TX to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to St. Louis, MO, for the next 30 days.
With a price starting from $117, Friday is the cheapest day for a bus from San Antonio, TX to St. Louis, MO. Tuesday instead is the most expensive day with prices starting from $165.
Morning is the cheapest day time for bus tickets from San Antonio, TX to St. Louis, MO, with $117. Afternoon is the most expensive time of the day with prices starting from $150.

How to save money travelling from San Antonio, TX to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to St. Louis, MO are also emptier.

Beloved bus companies from San Antonio, TX to St. Louis, MO

These are the most booked bus companies between San Antonio, TX to St. Louis, MO from our users.

Greyhound US from San Antonio, TX to St. Louis, MO

Greyhound US

Here you will find the key facts about the Greyhound US bus route San Antonio, TX to St. Louis, MO:

Cheapest Price $150
Fastest Bus 24h 15m
Earliest Bus 12:40 PM
Last Bus 12:40 PM
Daily Connections 1 Ø
Found on 6/16/2025

All bus stations and stops in San Antonio, TX and St. Louis, MO

In the map below, you can see where to find all bus stations in San Antonio, TX and St. Louis, MO.

Service and Comfort on the bus from San Antonio, TX to St. Louis, MO

Want to know which seat classes are available on the buses from San Antonio, TX to St. Louis, MO? Or which bus companies serve the route San Antonio, TX to St. Louis, MO? Below you will find answers to your questions.

FAQs about the San Antonio, TX to St. Louis, MO bus

How much does a San Antonio, TX St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $117 and takes 23h 35m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to St. Louis, MO?

This route is offered by 3 companies with a range of ticket prices between $117 and $179. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from San Antonio, TX to St. Louis, MO each day?

Every day, the San Antonio, TX to St. Louis, MO bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to St. Louis, MO take?

The fastest bus from San Antonio, TX to St. Louis, MO is offered by Greyhound Lines Mexico and takes 20h 40m. Bus tickets for this connection cost $145. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from San Antonio, TX starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to St. Louis, MO?

The latest bus trip departing from San Antonio, TX for St. Louis, MO starts at 7:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX St. Louis, MO route?

When traveling by bus from San Antonio, TX to St. Louis, MO, passengers can travel with FlixBus, Greyhound Lines Mexico and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and St. Louis, MO?

You can check all the direct connections between San Antonio, TX and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound Lines Mexico and Greyhound US.

What can I take with me on the San Antonio, TX to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route San Antonio, TX to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to St. Louis, MO

Here’s an overview of the most popular bus routes to San Antonio, TX and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses to San Antonio, TX from Corpus Christi Buses to San Antonio, TX from Corpus Christi
Buses McAllen, TX - San Antonio, TX Buses McAllen, TX - San Antonio, TX
Bus Eagle Pass, TX - San Antonio, TX Bus Eagle Pass, TX - San Antonio, TX
From El Paso, TX to San Antonio, TX bus From El Paso, TX to San Antonio, TX bus
Buses Dallas - St. Louis, MO Buses Dallas - St. Louis, MO
Bus from Houston to St. Louis, MO Bus from Houston to St. Louis, MO
Buses Columbia, MO - St. Louis, MO Buses Columbia, MO - St. Louis, MO
Buses to St. Louis, MO from Chicago Buses to St. Louis, MO from Chicago
Popular Airport Shuttles to San Antonio, TX and to St. Louis, MO
CheckMyBus › Buses in USA › Bus to San Antonio, TX › Bus to St. Louis, MO

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To show you the best bus offers, we and our partners use technical, analytical, and marketing cookies to personalize the ads. We remember your anonymized details to provide a personalized experience.