Bus Tampa to San Antonio, TX: Compare prices and save money

Compare all timetables for the bus from Tampa to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from Tampa to San Antonio, TX from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

Wednesday

$145

Thursday

Friday

$221

Saturday

Sunday

$220

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	29h 10m	11:10 AM	Tampa	Marion Street	3:20 PM	San Antonio, TX	Bus Station	Economy	$145	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/24/2025 11:10:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/25/2025 3:20:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 29h 10m
FlixBus	48h 20m	9:50 PM	Tampa	USF	9:10 PM	San Antonio, TX	Pearl District	Economy	$145	A Bus from FlixBus goes from USF, Tampa (USA) at 12/24/2025 9:50:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/26/2025 9:10:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 48h 20m
FlixBus	47h 35m	10:35 PM	Tampa	Marion Street	9:10 PM	San Antonio, TX	Pearl District	Economy	$145	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/24/2025 10:35:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/26/2025 9:10:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 47h 35m
FlixBus	36h 5m	5:55 PM	Tampa	USF	5:00 AM	San Antonio, TX	Bus Station	Economy	$146	A Bus from FlixBus goes from USF, Tampa (USA) at 12/24/2025 5:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 12/26/2025 5:00:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 36h 5m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	47h 35m	10:35 PM	Tampa	Marion Street	9:10 PM	San Antonio, TX	Pearl District	Economy	$221	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/26/2025 10:35:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/28/2025 9:10:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 47h 35m
FlixBus	48h 20m	9:50 PM	Tampa	USF	9:10 PM	San Antonio, TX	Pearl District	Economy	$221	A Bus from FlixBus goes from USF, Tampa (USA) at 12/26/2025 9:50:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/28/2025 9:10:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 48h 20m
Greyhound US	31h 45m	6:10 AM	Tampa	Marion Street	12:55 PM	San Antonio, TX	Bus Station	Economy	$229	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/26/2025 6:10:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/27/2025 12:55:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 31h 45m
Greyhound US	40h 0m	6:10 AM	Tampa	Marion Street	9:10 PM	San Antonio, TX	Pearl District	Economy	$229	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/26/2025 6:10:00 AM to Pearl District, San Antonio, TX (USA) arriving at 12/27/2025 9:10:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 40h 0m
Greyhound US	29h 10m	11:10 AM	Tampa	Marion Street	3:20 PM	San Antonio, TX	Bus Station	Economy	$231	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/26/2025 11:10:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/27/2025 3:20:00 PM. 50 Economy ticket for $231 per person are available. Travel duration is 29h 10m

Did you know that if you travel from Tampa to San Antonio, TX via Houston, you can save more than $43? You can find the corresponding connections below.
- Busbud
  
  36h 45m
  
  0
  
  10:35 PM
  
  Tampa
  Marion Street
  
  5:15 AM
  
  Houston
  Downtown Houston
  
  0
  
  Economy
  
  $140
  
  A Bus from Busbud goes from Marion Street, Tampa (USA) at 12/24/2025 10:35:00 PM to Downtown Houston, Houston (USA) arriving at 12/26/2025 5:15:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 31h 40m
- Busbud
  
  4h 20m
  
  0
  
  6:00 AM
  
  Houston
  Harrisburg Blvd Station
  
  10:20 AM
  
  San Antonio, TX
  Bus Station
  
  0
  
  Economy
  
  $38
  
  A Bus from Busbud goes from Harrisburg Blvd Station, Houston (USA) at 12/26/2025 6:00:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/26/2025 10:20:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 4h 20m
Travel time is 8h 35m longer, but you will save $43

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	41h 45m	10:35 PM	Tampa	Marion Street	3:20 PM	San Antonio, TX	Bus Station	Economy	$220	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/28/2025 10:35:00 PM to Bus Station, San Antonio, TX (USA) arriving at 12/30/2025 3:20:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 41h 45m
FlixBus	42h 30m	9:50 PM	Tampa	USF	3:20 PM	San Antonio, TX	Bus Station	Economy	$220	A Bus from FlixBus goes from USF, Tampa (USA) at 12/28/2025 9:50:00 PM to Bus Station, San Antonio, TX (USA) arriving at 12/30/2025 3:20:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 42h 30m
Greyhound US	34h 5m	6:10 AM	Tampa	Marion Street	3:15 PM	San Antonio, TX	Bus Station	Economy	$229	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/28/2025 6:10:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/29/2025 3:15:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 34h 5m
FlixBus	49h 50m	10:35 PM	Tampa	Marion Street	11:25 PM	San Antonio, TX	Pearl District	Economy	$230	A Bus from FlixBus goes from Marion Street, Tampa (USA) at 12/28/2025 10:35:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/30/2025 11:25:00 PM. 50 Economy ticket for $230 per person are available. Travel duration is 49h 50m
Greyhound US	29h 10m	11:10 AM	Tampa	Marion Street	3:20 PM	San Antonio, TX	Bus Station	Economy	$231	A Bus from Greyhound US goes from Marion Street, Tampa (USA) at 12/28/2025 11:10:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/29/2025 3:20:00 PM. 50 Economy ticket for $231 per person are available. Travel duration is 29h 10m

Did you know that if you travel from Tampa to San Antonio, TX via Houston, you can save more than $47? You can find the corresponding connections below.
- Busbud
  
  36h 50m
  
  0
  
  11:10 AM
  
  Tampa
  Marion Street
  
  11:20 AM
  
  Houston
  Harrisburg Blvd Station
  
  0
  
  Economy
  
  $141
  
  A Bus from Busbud goes from Marion Street, Tampa (USA) at 12/29/2025 11:10:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 12/30/2025 11:20:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 25h 10m
- Busbud
  
  3h 10m
  
  0
  
  7:50 PM
  
  Houston
  Uptown/Upper Kirby
  
  11:00 PM
  
  San Antonio, TX
  Bus Station
  
  0
  
  Economy
  
  $32
  
  A Bus from Busbud goes from Uptown/Upper Kirby, Houston (USA) at 12/30/2025 7:50:00 PM to Bus Station, San Antonio, TX (USA) arriving at 12/30/2025 11:00:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 3h 10m
Travel time is 8h 40m longer, but you will save $47

Best Price Offer: The price for the cheapest bus from Tampa to San Antonio, TX is $145 on 12/24/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Tampa and San Antonio, TX

See here how frequent the connections between Tampa and San Antonio, TX are, during different times and days of the week.

Sunday is the busiest day, with more than 8 daily buses from Tampa to San Antonio, TX. Wednesday has instead the fewest connections, with only 6 daily coaches between Tampa and San Antonio, TX.

The busiest time of the day is the Evening, with 12 buses from Tampa to San Antonio, TX, while Afternoon sees the fewest connections between Tampa and San Antonio, TX, with 3 offers.

Facts about the bus from Tampa to San Antonio, TX

Compare all providers like FlixBus and Greyhound US that travel 7 times every day by bus from Tampa to San Antonio, TX in one click! Book your bus ticket from Tampa to San Antonio, TX starting from $145!

Cheapest Bus	$145
Fastest Bus	28h 10m
Earliest Bus	11:10 AM
Latest Bus	10:35 PM
Daily Bus Routes	7 Ø
Distance	976.3 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Tampa to San Antonio, TX

Every day, 7 buses from 2 bus companies leave Tampa for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/22/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

$145

Thursday 12/25

Friday 12/26

$221

Saturday 12/27

Sunday 12/28

$220

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

Sunday 01/11

Monday 01/12

Tuesday 01/13

Wednesday 01/14

Thursday 01/15

Friday 01/16

Saturday 01/17

The cheapest time to travel from Tampa to San Antonio, TX

See here on which day and which time of the day you can find the cheapest bus ticket from Tampa to San Antonio, TX, for the next 30 days.

With a price starting from $145, Wednesday is the cheapest day for a bus from Tampa to San Antonio, TX. Friday instead is the most expensive day with prices starting from $221.

Evening is the cheapest day time for bus tickets from Tampa to San Antonio, TX, with $145. Afternoon is the most expensive time of the day with prices starting from $146.

How to save money travelling from Tampa to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tampa to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tampa to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tampa to San Antonio, TX are also emptier.

All bus stations and stops in Tampa and San Antonio, TX

In the map below, you can see where to find all bus stations in Tampa and San Antonio, TX.

Marion Street

N Marion St 1211

USF

USF Holly Drive 3755

Greyhound Bus Station

East Polk Street 602

Western Union

Tampa Gateway Blvd, I 4 Exit 10 11706

Port of Tampa Cruise Terminals

Channelside Dr. 1101

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

W. Southcross & Buffalo Bus Stop

Commerce & Bowie Bus Stop

Service and Comfort on the bus from Tampa to San Antonio, TX

Want to know which seat classes are available on the buses from Tampa to San Antonio, TX? Or which bus companies serve the route Tampa to San Antonio, TX? Below you will find answers to your questions.

FAQs about the Tampa to San Antonio, TX bus

How much does a Tampa San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $145 and takes 47h 20m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from Tampa to San Antonio, TX?

This route is offered by 2 companies with a range of ticket prices between $145 and $321. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from Tampa to San Antonio, TX each day?

Every day, the Tampa to San Antonio, TX bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tampa to San Antonio, TX take?

The fastest bus from Tampa to San Antonio, TX is offered by Greyhound US and takes 28h 10m. Bus tickets for this connection cost $145. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tampa to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from Tampa starts at 11:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tampa to San Antonio, TX?

The latest bus trip departing from Tampa for San Antonio, TX starts at 10:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tampa San Antonio, TX route?

When traveling by bus from Tampa to San Antonio, TX, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tampa and San Antonio, TX?

You can check all the direct connections between Tampa and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Tampa to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tampa San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tampa San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tampa to San Antonio, TX on your planned travel date.

How does CheckMyBus find the best bus deals from Tampa to San Antonio, TX?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Tampa and San Antonio, TX. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Tampa to San Antonio, TX?

Prices and availability for 7 trips between Tampa and San Antonio, TX change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Tampa to San Antonio, TX

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tampa and to San Antonio, TX

Here’s an overview of the most popular bus routes to Tampa and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!