Bus Orlando, FL to San Antonio, TX - Compare all Companies

Compare all timetables for the bus from Orlando, FL to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from Orlando, FL to San Antonio, TX from various bus operators like FlixBus or Greyhound US for the next days.

today

$111

tomorrow

$119

Monday

Tuesday

$109

Wednesday

Thursday

Friday

$113

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 0m	1:50 PM	Orlando, FL	Bus Station	3:50 PM	San Antonio, TX	Bus Station	Economy	$111	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 9/19/2026 1:50:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/20/2026 3:50:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 27h 0m
Greyhound US	32h 15m	5:40 AM	Orlando, FL	Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$112	A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 9/19/2026 5:40:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/20/2026 12:55:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 32h 15m
Greyhound US	39h 45m	5:40 AM	Orlando, FL	Bus Station	8:25 PM	San Antonio, TX	Pearl District	Economy	$112	A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 9/19/2026 5:40:00 AM to Pearl District, San Antonio, TX (USA) arriving at 9/20/2026 8:25:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 39h 45m
FlixBus	41h 55m	10:55 PM	Orlando, FL	Bus Station	3:50 PM	San Antonio, TX	Bus Station	Economy	$112	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 9/19/2026 10:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/21/2026 3:50:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 41h 55m
FlixBus	35h 30m	1:50 PM	Orlando, FL	Bus Station	12:20 AM	San Antonio, TX	Pearl District	Economy	$112	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 9/19/2026 1:50:00 PM to Pearl District, San Antonio, TX (USA) arriving at 9/21/2026 12:20:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 35h 30m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 0m	1:50 PM	Orlando, FL	Bus Station	3:50 PM	San Antonio, TX	Bus Station	Economy	$119	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 9/20/2026 1:50:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/21/2026 3:50:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 27h 0m
FlixBus	27h 45m	1:05 PM	Orlando, FL	Florida Mall	3:50 PM	San Antonio, TX	Bus Station	Economy	$119	A Bus from FlixBus goes from Florida Mall, Orlando, FL (USA) at 9/20/2026 1:05:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/21/2026 3:50:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 27h 45m
Greyhound US	34h 40m	5:40 AM	Orlando, FL	Bus Station	3:20 PM	San Antonio, TX	Bus Station	Economy	$120	A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 9/20/2026 5:40:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/21/2026 3:20:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 34h 40m
Greyhound US	42h 30m	5:40 AM	Orlando, FL	Bus Station	11:10 PM	San Antonio, TX	Pearl District	Economy	$120	A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 9/20/2026 5:40:00 AM to Pearl District, San Antonio, TX (USA) arriving at 9/21/2026 11:10:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 42h 30m
FlixBus	41h 55m	10:55 PM	Orlando, FL	Bus Station	3:50 PM	San Antonio, TX	Bus Station	Economy	$121	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 9/20/2026 10:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/22/2026 3:50:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 41h 55m

Did you know that if you travel from Orlando, FL to San Antonio, TX via Houston, you can save more than $18? You can find the corresponding connections below.
- Greyhound US
  
  29h 40m
  
  0
  
  5:40 AM
  
  Orlando, FL
  Bus Station
  
  5:05 AM
  
  Houston
  Downtown Houston
  
  0
  
  Economy
  
  $73
  
  A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 9/22/2026 5:40:00 AM to Downtown Houston, Houston (USA) arriving at 9/23/2026 5:05:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 24h 25m
- Valley Transit
  
  4h 20m
  
  0
  
  6:00 AM
  
  Houston
  Harrisburg Blvd Station
  
  10:20 AM
  
  San Antonio, TX
  Bus Station
  
  0
  
  Economy
  
  $28
  
  A Bus from Valley Transit goes from Harrisburg Blvd Station, Houston (USA) at 9/23/2026 6:00:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/23/2026 10:20:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 4h 20m
Travel time is 3h 40m longer, but you will save $18

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	41h 55m	10:55 PM	Orlando, FL	Bus Station	3:50 PM	San Antonio, TX	Bus Station	Economy	$109	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 9/22/2026 10:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/24/2026 3:50:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 41h 55m
Greyhound US	32h 15m	5:40 AM	Orlando, FL	Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$110	A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 9/22/2026 5:40:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/23/2026 12:55:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 32h 15m
Greyhound US	30h 35m	10:15 AM	Orlando, FL	Bus Station	3:50 PM	San Antonio, TX	Bus Station	Economy	$110	A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 9/22/2026 10:15:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/23/2026 3:50:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 30h 35m
Greyhound US	39h 45m	5:40 AM	Orlando, FL	Bus Station	8:25 PM	San Antonio, TX	Pearl District	Economy	$110	A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 9/22/2026 5:40:00 AM to Pearl District, San Antonio, TX (USA) arriving at 9/23/2026 8:25:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 39h 45m
FlixBus	36h 15m	4:35 AM	Orlando, FL	Florida Mall	3:50 PM	San Antonio, TX	Bus Station	Economy	$111	A Bus from FlixBus goes from Florida Mall, Orlando, FL (USA) at 9/22/2026 4:35:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/23/2026 3:50:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 36h 15m

Did you know that if you travel from Orlando, FL to San Antonio, TX via Houston, you can save more than $11? You can find the corresponding connections below.
- FlixBus
  
  41h 55m
  
  0
  
  10:55 PM
  
  Orlando, FL
  Bus Station
  
  7:10 AM
  
  Houston
  Harrisburg Blvd Station
  
  0
  
  Economy
  
  $72
  
  A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 9/22/2026 10:55:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 9/24/2026 7:10:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 33h 15m
- Greyhound US
  
  3h 55m
  
  0
  
  11:55 AM
  
  Houston
  Harrisburg Blvd Station
  
  3:50 PM
  
  San Antonio, TX
  Bus Station
  
  0
  
  Economy
  
  $26
  
  A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 9/24/2026 11:55:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/24/2026 3:50:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 3h 55m
Travel time is 12h 20m longer, but you will save $11

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	41h 55m	10:55 PM	Orlando, FL	Bus Station	3:50 PM	San Antonio, TX	Bus Station	Economy	$113	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 9/25/2026 10:55:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/27/2026 3:50:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 41h 55m
FlixBus	33h 45m	2:00 PM	Orlando, FL	Florida Mall	10:45 PM	San Antonio, TX	Bus Station	Economy	$113	A Bus from FlixBus goes from Florida Mall, Orlando, FL (USA) at 9/25/2026 2:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/26/2026 10:45:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 33h 45m
Greyhound US	39h 45m	5:40 AM	Orlando, FL	Bus Station	8:25 PM	San Antonio, TX	Pearl District	Economy	$114	A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 9/25/2026 5:40:00 AM to Pearl District, San Antonio, TX (USA) arriving at 9/26/2026 8:25:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 39h 45m
FlixBus	27h 0m	1:50 PM	Orlando, FL	Bus Station	3:50 PM	San Antonio, TX	Bus Station	Economy	$114	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 9/25/2026 1:50:00 PM to Bus Station, San Antonio, TX (USA) arriving at 9/26/2026 3:50:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 27h 0m
Greyhound US	32h 15m	5:40 AM	Orlando, FL	Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$115	A Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 9/25/2026 5:40:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/26/2026 12:55:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 32h 15m

Did you know that if you travel from Orlando, FL to San Antonio, TX via Houston, you can save more than $13? You can find the corresponding connections below.
- FlixBus
  
  34h 50m
  
  0
  
  6:00 AM
  
  Orlando, FL
  Bus Station
  
  7:10 AM
  
  Houston
  Harrisburg Blvd Station
  
  0
  
  Economy
  
  $73
  
  A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 9/22/2026 6:00:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 9/23/2026 7:10:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 26h 10m
- Greyhound US
  
  3h 55m
  
  0
  
  11:55 AM
  
  Houston
  Harrisburg Blvd Station
  
  3:50 PM
  
  San Antonio, TX
  Bus Station
  
  0
  
  Economy
  
  $27
  
  A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 9/23/2026 11:55:00 AM to Bus Station, San Antonio, TX (USA) arriving at 9/23/2026 3:50:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 3h 55m
Travel time is 8h 50m longer, but you will save $13

Best Price Offer: The price for the cheapest bus from Orlando, FL to San Antonio, TX is $89 on 9/29/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Orlando, FL and San Antonio, TX

See here how frequent the connections between Orlando, FL and San Antonio, TX are, during different times and days of the week.

Saturday is the busiest day, with more than 22 daily buses from Orlando, FL to San Antonio, TX. Sunday has instead the fewest connections, with only 10 daily coaches between Orlando, FL and San Antonio, TX.

The busiest time of the day is the Afternoon, with 20 buses from Orlando, FL to San Antonio, TX, while Morning sees the fewest connections between Orlando, FL and San Antonio, TX, with 2 offers.

Facts about the bus from Orlando, FL to San Antonio, TX

Compare all providers like FlixBus and Greyhound US that travel 13 times every day by bus from Orlando, FL to San Antonio, TX in one click! Book your bus ticket from Orlando, FL to San Antonio, TX starting from $89!

Cheapest Bus	$89
Fastest Bus	26h 0m
Earliest Bus	5:40 AM
Latest Bus	10:55 PM
Daily Bus Routes	13 Ø
Distance	1,035.1 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Orlando, FL to San Antonio, TX

Every day, 13 buses from 2 bus companies leave Orlando, FL for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/13

Monday 09/14

Tuesday 09/15

Wednesday 09/16

Thursday 09/17

Friday 09/18

Saturday 09/19

$115

Sunday 09/20

$119

Monday 09/21

Tuesday 09/22

$113

Wednesday 09/23

Thursday 09/24

Friday 09/25

$113

Saturday 09/26

Sunday 09/27

$112

Monday 09/28

Tuesday 09/29

$89

Wednesday 09/30

Thursday 10/01

Friday 10/02

$105

Saturday 10/03

$108

Sunday 10/04

$112

Monday 10/05

$113

Tuesday 10/06

$98

Wednesday 10/07

$94

Thursday 10/08

$115

Friday 10/09

$110

Saturday 10/10

The cheapest time to travel from Orlando, FL to San Antonio, TX

See here on which day and which time of the day you can find the cheapest bus ticket from Orlando, FL to San Antonio, TX, for the next 30 days.

With a price starting from $89, Tuesday is the cheapest day for a bus from Orlando, FL to San Antonio, TX. Sunday instead is the most expensive day with prices starting from $112.

Night is the cheapest day time for bus tickets from Orlando, FL to San Antonio, TX, with $89. Afternoon is the most expensive time of the day with prices starting from $111.

How to save money travelling from Orlando, FL to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Orlando, FL to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Orlando, FL to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Orlando, FL to San Antonio, TX are also emptier.

Beloved bus companies from Orlando, FL to San Antonio, TX

These are the most booked bus companies between Orlando, FL to San Antonio, TX from our users.

Greyhound US from Orlando, FL to San Antonio, TX

Here you will find the key facts about the Greyhound US bus route Orlando, FL to San Antonio, TX:

Cheapest Price	$110
Fastest Bus	29h 35m
Earliest Bus	5:40 AM
Last Bus	5:40 AM
Daily Connections	3 Ø
Found on	8/26/2026

FlixBus from Orlando, FL to San Antonio, TX

Here you will find the key facts about the FlixBus bus route Orlando, FL to San Antonio, TX:

Cheapest Price	$109
Fastest Bus	26h 0m
Earliest Bus	1:05 PM
Last Bus	10:55 PM
Daily Connections	10 Ø
Found on	8/26/2026

All bus stations and stops in Orlando, FL and San Antonio, TX

In the map below, you can see where to find all bus stations in Orlando, FL and San Antonio, TX.

Bus Station

N John Young Pkwy 555

Florida Mall

Florida Mall Avenue 1602

RedCoach Station

Belle Isle

Universal Studio Orlando Resort

Universal Blvd 5800

Jet Set Express Orlando Terminal

L B McLeod Rd 3718

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

Commerce & Bowie Bus Stop

W. Southcross & Buffalo Bus Stop

Service and Comfort on the bus from Orlando, FL to San Antonio, TX

Want to know which seat classes are available on the buses from Orlando, FL to San Antonio, TX? Or which bus companies serve the route Orlando, FL to San Antonio, TX? Below you will find answers to your questions.

FAQs about the Orlando, FL to San Antonio, TX bus

How much does a Orlando, FL San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $89 and takes 40h 55m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from Orlando, FL to San Antonio, TX?

This route is offered by 2 companies with a range of ticket prices between $89 and $191. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from Orlando, FL to San Antonio, TX each day?

Every day, the Orlando, FL to San Antonio, TX bus route is served by approximately 13 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Orlando, FL to San Antonio, TX take?

The fastest bus from Orlando, FL to San Antonio, TX is offered by FlixBus and takes 26h 0m. Bus tickets for this connection cost $111. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Orlando, FL to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from Orlando, FL starts at 5:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Orlando, FL to San Antonio, TX?

The latest bus trip departing from Orlando, FL for San Antonio, TX starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Orlando, FL San Antonio, TX route?

When traveling by bus from Orlando, FL to San Antonio, TX, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Orlando, FL and San Antonio, TX?

You can check all the direct connections between Orlando, FL and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Orlando, FL to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Orlando, FL San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Orlando, FL San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Orlando, FL to San Antonio, TX on your planned travel date.

How does CheckMyBus find the best bus deals from Orlando, FL to San Antonio, TX?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 13 daily trips between Orlando, FL and San Antonio, TX. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Orlando, FL to San Antonio, TX?

Prices and availability for 13 trips between Orlando, FL and San Antonio, TX change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Orlando, FL to San Antonio, TX

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Orlando, FL and to San Antonio, TX

Here’s an overview of the most popular bus routes to Orlando, FL and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!