Bus from Philadelphia to St. Louis, MO from $93

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Compare all timetables for the bus from Philadelphia to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Philadelphia to St. Louis, MO from various bus operators like FlixBus or Greyhound US for the next days.
today
from $114
tomorrow
from $117
Saturday
from $93
Sunday
from $110
Monday
Tuesday
from $98
Wednesday
from $96

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    19h 40m
    0
    3:55 AM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $114
  • FlixBus
    25h 35m
    0
    1:45 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    3:20 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $115
  • Greyhound US
    21h 50m
    0
    5:30 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    3:20 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $115
  • Greyhound US
    27h 25m
    0
    11:55 AM
    Philadelphia
    IRS Building
    3:20 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $115
  • FlixBus
    27h 15m
    0
    3:10 AM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $128

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    19h 45m
    0
    10:40 AM
    Philadelphia
    Convention Center
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $117
  • Greyhound US
    21h 50m
    0
    5:30 PM
    Philadelphia
    Convention Center
    3:20 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $127
  • Greyhound US
    19h 40m
    0
    3:55 AM
    Philadelphia
    Convention Center
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $132
  • FlixBus
    27h 35m
    0
    6:25 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    10:00 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $133
  • FlixBus
    32h 55m
    0
    9:30 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $135

Cheapest bus trips Saturday

Prices are for one way and one person
  • Greyhound US
    19h 45m
    0
    10:40 AM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $93
  • Greyhound US
    19h 40m
    0
    3:55 AM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $117
  • FlixBus
    27h 35m
    0
    6:25 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    10:00 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $118
  • FlixBus
    27h 15m
    0
    3:10 AM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $119
  • FlixBus
    25h 35m
    0
    1:45 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    3:20 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $119

Cheapest bus trips Sunday

Prices are for one way and one person
  • Greyhound US
    19h 40m
    0
    3:55 AM
    Philadelphia
    Convention Center
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $110
  • Greyhound US
    19h 45m
    0
    10:40 AM
    Philadelphia
    Convention Center
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $113
  • FlixBus
    26h 50m
    0
    8:45 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $117
  • Greyhound US
    27h 5m
    0
    8:30 PM
    Philadelphia
    Convention Center
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $117
  • FlixBus
    25h 35m
    0
    1:45 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    3:20 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $119

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    19h 45m
    0
    10:40 AM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $98
  • Greyhound US
    19h 40m
    0
    3:55 AM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $110
  • FlixBus
    35h 40m
    0
    10:20 AM
    Philadelphia
    JFK & Broad
    10:00 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $172
  • Greyhound US
    21h 50m
    0
    5:30 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    3:20 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $177
  • FlixBus
    27h 15m
    0
    3:10 AM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $178

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Greyhound US
    19h 45m
    0
    10:40 AM
    Philadelphia
    Convention Center
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $96
  • Greyhound US
    19h 45m
    0
    10:40 AM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    6:25 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $98
  • Greyhound US
    19h 40m
    0
    3:55 AM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $117
  • FlixBus
    27h 35m
    0
    6:25 PM
    Philadelphia
    Spring Garden St & 2nd St Bus Stop
    10:00 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $136
  • FlixBus
    35h 40m
    0
    10:20 AM
    Philadelphia
    JFK & Broad
    10:00 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $138

Frequency of bus connections between Philadelphia and St. Louis, MO

See here how frequent the connections between Philadelphia and St. Louis, MO are, during different times and days of the week.
Wednesday is the busiest day, with more than 25 daily buses from Philadelphia to St. Louis, MO. Tuesday has instead the fewest connections, with only 12 daily coaches between Philadelphia and St. Louis, MO.
The busiest time of the day is the Evening, with 38 buses from Philadelphia to St. Louis, MO, while Morning sees the fewest connections between Philadelphia and St. Louis, MO, with 14 offers.

Facts about the bus from Philadelphia to St. Louis, MO

Compare all providers like FlixBus and Greyhound US that travel 15 times every day by bus from Philadelphia to St. Louis, MO in one click! Book your bus ticket from Philadelphia to St. Louis, MO starting from $93!

Cheapest Bus $93
Fastest Bus 19h 40m
Earliest Bus 3:10 AM
Latest Bus 9:30 PM
Daily Bus Routes 15 Ø
Distance 807.9 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Philadelphia to St. Louis, MO

Every day, 15 buses from 2 bus companies leave Philadelphia for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/15/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/11
Monday 05/12
Tuesday 05/13
Wednesday 05/14
Thursday 05/15
$114
Friday 05/16
$117
Saturday 05/17
$93
Sunday 05/18
$110
Monday 05/19
Tuesday 05/20
$98
Wednesday 05/21
$96
Thursday 05/22
$107
Friday 05/23
Saturday 05/24
$93
Sunday 05/25
$98
Monday 05/26
$96
Tuesday 05/27
$82
Wednesday 05/28
Thursday 05/29
Friday 05/30
$81
Saturday 05/31
$95
Sunday 06/01
Monday 06/02
Tuesday 06/03
Wednesday 06/04
Thursday 06/05
Friday 06/06
Saturday 06/07

The cheapest time to travel from Philadelphia to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Philadelphia to St. Louis, MO, for the next 30 days.
With a price starting from $93, Saturday is the cheapest day for a bus from Philadelphia to St. Louis, MO. Friday instead is the most expensive day with prices starting from $117.
Morning is the cheapest day time for bus tickets from Philadelphia to St. Louis, MO, with $93. Evening is the most expensive time of the day with prices starting from $117.

How to save money travelling from Philadelphia to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Philadelphia to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Philadelphia to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Philadelphia to St. Louis, MO are also emptier.

Beloved bus companies from Philadelphia to St. Louis, MO

These are the most booked bus companies between Philadelphia to St. Louis, MO from our users.

FlixBus from Philadelphia to St. Louis, MO

FlixBus

Here you will find the key facts about the FlixBus bus route Philadelphia to St. Louis, MO:

Cheapest Price $115
Fastest Bus 25h 35m
Earliest Bus 3:10 AM
Last Bus 9:30 PM
Daily Connections 7 Ø
Found on 5/12/2025

All bus stations and stops in Philadelphia and St. Louis, MO

In the map below, you can see where to find all bus stations in Philadelphia and St. Louis, MO.

Service and Comfort on the bus from Philadelphia to St. Louis, MO

Want to know which seat classes are available on the buses from Philadelphia to St. Louis, MO? Or which bus companies serve the route Philadelphia to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Philadelphia to St. Louis, MO bus

How much does a Philadelphia St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $93 and takes 19h 45m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Philadelphia to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $93 and $195. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Philadelphia to St. Louis, MO each day?

Every day, the Philadelphia to St. Louis, MO bus route is served by approximately 15 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Philadelphia to St. Louis, MO take?

The fastest bus from Philadelphia to St. Louis, MO is offered by Greyhound US and takes 19h 40m. Bus tickets for this connection cost $114. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Philadelphia to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Philadelphia starts at 3:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Philadelphia to St. Louis, MO?

The latest bus trip departing from Philadelphia for St. Louis, MO starts at 9:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Philadelphia St. Louis, MO route?

When traveling by bus from Philadelphia to St. Louis, MO, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Philadelphia and St. Louis, MO?

You can check all the direct connections between Philadelphia and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Philadelphia to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Philadelphia St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Philadelphia St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Philadelphia to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Philadelphia to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Philadelphia and to St. Louis, MO

Here’s an overview of the most popular bus routes to Philadelphia and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Philadelphia and to St. Louis, MO
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