Which bus from Mexico City to St. Louis, MO is the cheapest?

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Compare all timetables for the bus from Mexico City to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Mexico City to St. Louis, MO from various bus operators like Flix Mexico for the next days.

today
tomorrow
$107
Tuesday
Wednesday
Thursday
Friday
$124
Saturday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 50h 55m 9:00 AM Mexico City San Pedro Santa Clara Bus Stop 12:55 PM St. Louis, MO Gateway Station  Economy $107
Flix Mexico 61h 35m 10:20 PM Mexico City San Pedro Santa Clara Bus Stop 12:55 PM St. Louis, MO Gateway Station  Economy $107
Flix Mexico 50h 30m 9:25 AM Mexico City Fórum Buenavista 12:55 PM St. Louis, MO Gateway Station  Economy $107
Flix Mexico 61h 10m 10:45 PM Mexico City Fórum Buenavista 12:55 PM St. Louis, MO Gateway Station  Economy $107
Flix Mexico 47h 45m 10:00 PM Mexico City San Pedro Santa Clara Bus Stop 10:45 PM St. Louis, MO Gateway Station  Economy $109

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 47h 45m 10:00 PM Mexico City San Pedro Santa Clara Bus Stop 10:45 PM St. Louis, MO Gateway Station  Economy $124
Flix Mexico 47h 20m 10:25 PM Mexico City Fórum Buenavista 10:45 PM St. Louis, MO Gateway Station  Economy $124
Flix Mexico 50h 55m 9:00 AM Mexico City San Pedro Santa Clara Bus Stop 12:55 PM St. Louis, MO Gateway Station  Economy $126
Flix Mexico 50h 30m 9:25 AM Mexico City Fórum Buenavista 12:55 PM St. Louis, MO Gateway Station  Economy $126
Flix Mexico 55h 50m 10:20 PM Mexico City San Pedro Santa Clara Bus Stop 7:10 AM St. Louis, MO Gateway Station  Economy $139

Best Price Offer: The price for the cheapest bus from Mexico City to St. Louis, MO is $107 on 10/5/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Mexico City and St. Louis, MO

See here how frequent the connections between Mexico City and St. Louis, MO are, during different times and days of the week.
Monday is the busiest day, with more than 12 daily buses from Mexico City to St. Louis, MO. Friday has instead the fewest connections, with only 6 daily coaches between Mexico City and St. Louis, MO.
The busiest time of the day is the Evening, with 12 buses from Mexico City to St. Louis, MO, while Morning sees the fewest connections between Mexico City and St. Louis, MO, with 6 offers.

Facts about the bus from Mexico City to St. Louis, MO

Compare all providers like Flix Mexico that travel 9 times every day by bus from Mexico City to St. Louis, MO in one click! Book your bus ticket from Mexico City to St. Louis, MO starting from $107!

Cheapest Bus $107
Fastest Bus 48h 20m
Earliest Bus 9:00 AM
Latest Bus 10:45 PM
Daily Bus Routes 9 Ø
Distance 1,430.1 miles
Bus Companies Flix Mexico

Cheapest bus connections from Mexico City to St. Louis, MO

Every day, 9 buses from 1 bus companies leave Mexico City for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/04/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 10/04
Monday 10/05
$109
Tuesday 10/06
Wednesday 10/07
Thursday 10/08
Friday 10/09
$124
Saturday 10/10
Sunday 10/11
$110
Monday 10/12
Tuesday 10/13
$112
Wednesday 10/14
Thursday 10/15
Friday 10/16
$131
Saturday 10/17
$146
Sunday 10/18
$142
Monday 10/19
$130
Tuesday 10/20
$130
Wednesday 10/21
Thursday 10/22
Friday 10/23
$138
Saturday 10/24
Sunday 10/25
$132
Monday 10/26
$116
Tuesday 10/27
$132
Wednesday 10/28
Thursday 10/29
Friday 10/30
Saturday 10/31

The cheapest time to travel from Mexico City to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Mexico City to St. Louis, MO, for the next 30 days.
With a price starting from $107, Monday is the cheapest day for a bus from Mexico City to St. Louis, MO. Friday instead is the most expensive day with prices starting from $124.
Evening is the cheapest day time for bus tickets from Mexico City to St. Louis, MO, with $107. Morning is the most expensive time of the day with prices starting from $107.

How to save money travelling from Mexico City to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mexico City to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mexico City to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mexico City to St. Louis, MO are also emptier.

Beloved bus companies from Mexico City to St. Louis, MO

These are the most booked bus companies between Mexico City to St. Louis, MO from our users.

Flix Mexico from Mexico City to St. Louis, MO

Flix Mexico

Here you will find the key facts about the Flix Mexico bus route Mexico City to St. Louis, MO:

Cheapest Price $107
Fastest Bus 48h 20m
Earliest Bus 9:00 AM
Last Bus 10:45 PM
Daily Connections 9 Ø
Found on 9/9/2026

All bus stations and stops in Mexico City and St. Louis, MO

In the map below, you can see where to find all bus stations in Mexico City and St. Louis, MO.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mexico City to St. Louis, MO? Compare all modes of transports from Mexico City to St. Louis, MO.

Service and Comfort on the bus from Mexico City to St. Louis, MO

Want to know which seat classes are available on the buses from Mexico City to St. Louis, MO? Or which bus companies serve the route Mexico City to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Mexico City to St. Louis, MO bus

How much does a Mexico City St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $107 and takes 62h 35m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Mexico City to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $107 and $139. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Mexico City to St. Louis, MO each day?

Every day, the Mexico City to St. Louis, MO bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mexico City to St. Louis, MO take?

The fastest bus from Mexico City to St. Louis, MO is offered by Flix Mexico and takes 48h 20m. Bus tickets for this connection cost $109. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mexico City to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Mexico City starts at 9:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mexico City to St. Louis, MO?

The latest bus trip departing from Mexico City for St. Louis, MO starts at 10:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mexico City St. Louis, MO route?

When traveling by bus from Mexico City to St. Louis, MO, passengers can travel with Flix Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mexico City and St. Louis, MO?

You can check all the direct connections between Mexico City and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Flix Mexico.

What can I take with me on the Mexico City to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mexico City St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mexico City St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mexico City to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Mexico City to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between Mexico City and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mexico City to St. Louis, MO?

Prices and availability for 9 trips between Mexico City and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mexico City to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mexico City and to St. Louis, MO

Here’s an overview of the most popular bus routes to Mexico City and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Mexico City and to St. Louis, MO
CheckMyBus › Buses in Mexico › Bus to Mexico City › Bus to St. Louis, MO

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