Bus Orlando, FL to St. Louis, MO - Compare all Companies

Compare all timetables for the bus from Orlando, FL to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Orlando, FL to St. Louis, MO from various bus operators like FlixBus for the next days.

today

tomorrow

$113

Wednesday

$96

Thursday

$101

Friday

$100

Saturday

$109

Sunday

$138

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 35m	2:45 PM	Orlando, FL	Bus Station	9:20 AM	St. Louis, MO	Gateway Station	Economy	$113	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/4/2026 2:45:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/5/2026 9:20:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 19h 35m
FlixBus	20h 20m	2:00 PM	Orlando, FL	Florida Mall	9:20 AM	St. Louis, MO	Gateway Station	Economy	$115	A Bus from FlixBus goes from Florida Mall, Orlando, FL (USA) at 8/4/2026 2:00:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/5/2026 9:20:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 20h 20m
FlixBus	23h 25m	10:55 PM	Orlando, FL	Bus Station	9:20 PM	St. Louis, MO	Gateway Station	Economy	$115	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/4/2026 10:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/5/2026 9:20:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 23h 25m
FlixBus	23h 35m	10:55 PM	Orlando, FL	Bus Station	9:30 PM	St. Louis, MO	Gateway Station	Economy	$125	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/4/2026 10:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/5/2026 9:30:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 23h 35m
FlixBus	19h 50m	9:05 PM	Orlando, FL	Bus Station	3:55 PM	St. Louis, MO	Gateway Station	Economy	$147	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/4/2026 9:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/5/2026 3:55:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 19h 50m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 20m	2:00 PM	Orlando, FL	Florida Mall	9:20 AM	St. Louis, MO	Gateway Station	Economy	$96	A Bus from FlixBus goes from Florida Mall, Orlando, FL (USA) at 8/5/2026 2:00:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/6/2026 9:20:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 20h 20m
FlixBus	19h 35m	2:45 PM	Orlando, FL	Bus Station	9:20 AM	St. Louis, MO	Gateway Station	Economy	$97	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/5/2026 2:45:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/6/2026 9:20:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 19h 35m
FlixBus	23h 25m	10:55 PM	Orlando, FL	Bus Station	9:20 PM	St. Louis, MO	Gateway Station	Economy	$97	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/5/2026 10:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/6/2026 9:20:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 23h 25m
FlixBus	19h 50m	9:05 PM	Orlando, FL	Bus Station	3:55 PM	St. Louis, MO	Gateway Station	Economy	$104	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/5/2026 9:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/6/2026 3:55:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 19h 50m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	21h 50m	12:30 PM	Orlando, FL	Bus Station	9:20 AM	St. Louis, MO	Gateway Station	Economy	$101	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/6/2026 12:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/7/2026 9:20:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 21h 50m
FlixBus	28h 10m	12:45 PM	Orlando, FL	Florida Mall	3:55 PM	St. Louis, MO	Gateway Station	Economy	$103	A Bus from FlixBus goes from Florida Mall, Orlando, FL (USA) at 8/6/2026 12:45:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/7/2026 3:55:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 28h 10m
FlixBus	23h 25m	10:55 PM	Orlando, FL	Bus Station	9:20 PM	St. Louis, MO	Gateway Station	Economy	$103	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/6/2026 10:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/7/2026 9:20:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 23h 25m
FlixBus	33h 35m	7:10 AM	Orlando, FL	Florida Mall	3:45 PM	St. Louis, MO	Gateway Station	Economy	$104	A Bus from FlixBus goes from Florida Mall, Orlando, FL (USA) at 8/6/2026 7:10:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 8/7/2026 3:45:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 33h 35m
FlixBus	34h 55m	1:05 PM	Orlando, FL	Florida Mall	11:00 PM	St. Louis, MO	Gateway Station	Economy	$104	A Bus from FlixBus goes from Florida Mall, Orlando, FL (USA) at 8/6/2026 1:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/7/2026 11:00:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 34h 55m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 35m	2:45 PM	Orlando, FL	Bus Station	9:20 AM	St. Louis, MO	Gateway Station	Economy	$100	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/7/2026 2:45:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/8/2026 9:20:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 19h 35m
FlixBus	19h 50m	9:05 PM	Orlando, FL	Bus Station	3:55 PM	St. Louis, MO	Gateway Station	Economy	$101	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/7/2026 9:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/8/2026 3:55:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 19h 50m
FlixBus	20h 20m	2:00 PM	Orlando, FL	Florida Mall	9:20 AM	St. Louis, MO	Gateway Station	Economy	$102	A Bus from FlixBus goes from Florida Mall, Orlando, FL (USA) at 8/7/2026 2:00:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/8/2026 9:20:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 20h 20m
FlixBus	23h 25m	10:55 PM	Orlando, FL	Bus Station	9:20 PM	St. Louis, MO	Gateway Station	Economy	$102	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/7/2026 10:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/8/2026 9:20:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 23h 25m
FlixBus	23h 35m	10:55 PM	Orlando, FL	Bus Station	9:30 PM	St. Louis, MO	Gateway Station	Economy	$131	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/7/2026 10:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/8/2026 9:30:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 23h 35m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 25m	10:55 PM	Orlando, FL	Bus Station	9:20 PM	St. Louis, MO	Gateway Station	Economy	$109	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/8/2026 10:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/9/2026 9:20:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 23h 25m
FlixBus	19h 35m	2:45 PM	Orlando, FL	Bus Station	9:20 AM	St. Louis, MO	Gateway Station	Economy	$112	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/8/2026 2:45:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/9/2026 9:20:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 19h 35m
FlixBus	20h 20m	2:00 PM	Orlando, FL	Florida Mall	9:20 AM	St. Louis, MO	Gateway Station	Economy	$114	A Bus from FlixBus goes from Florida Mall, Orlando, FL (USA) at 8/8/2026 2:00:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/9/2026 9:20:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 20h 20m
FlixBus	19h 50m	9:05 PM	Orlando, FL	Bus Station	3:55 PM	St. Louis, MO	Gateway Station	Economy	$126	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/8/2026 9:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/9/2026 3:55:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 19h 50m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 35m	10:55 PM	Orlando, FL	Bus Station	9:30 PM	St. Louis, MO	Gateway Station	Economy	$138	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/9/2026 10:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/10/2026 9:30:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 23h 35m
FlixBus	20h 20m	2:00 PM	Orlando, FL	Florida Mall	9:20 AM	St. Louis, MO	Gateway Station	Economy	$149	A Bus from FlixBus goes from Florida Mall, Orlando, FL (USA) at 8/9/2026 2:00:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/10/2026 9:20:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 20h 20m
FlixBus	19h 35m	2:45 PM	Orlando, FL	Bus Station	9:20 AM	St. Louis, MO	Gateway Station	Economy	$151	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/9/2026 2:45:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/10/2026 9:20:00 AM. 50 Economy ticket for $151 per person are available. Travel duration is 19h 35m
FlixBus	20h 5m	8:50 PM	Orlando, FL	Bus Station	3:55 PM	St. Louis, MO	Gateway Station	Economy	$190	A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/9/2026 8:50:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/10/2026 3:55:00 PM. 50 Economy ticket for $190 per person are available. Travel duration is 20h 5m

Did you know that if you travel from Orlando, FL to St. Louis, MO via Atlanta, GA, you can save more than $38? You can find the corresponding connections below.
- FlixBus
  
  19h 35m
  
  0
  
  2:45 PM
  
  Orlando, FL
  Bus Station
  
  11:25 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $43
  
  A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 8/11/2026 2:45:00 PM to Garnett Transit Station, Atlanta, GA (USA) arriving at 8/11/2026 11:25:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 8h 40m
- FlixBus
  
  10h 21m
  
  0
  
  11:59 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  9:20 AM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $57
  
  A Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 8/11/2026 11:59:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 8/12/2026 9:20:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 10h 21m
Travel time is 1h 0m longer, but you will save $38

Best Price Offer: The price for the cheapest bus from Orlando, FL to St. Louis, MO is $86 on 8/25/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Orlando, FL and St. Louis, MO

See here how frequent the connections between Orlando, FL and St. Louis, MO are, during different times and days of the week.

Thursday is the busiest day, with more than 12 daily buses from Orlando, FL to St. Louis, MO. Wednesday has instead the fewest connections, with only 4 daily coaches between Orlando, FL and St. Louis, MO.

The busiest time of the day is the Afternoon, with 22 buses from Orlando, FL to St. Louis, MO, while Morning sees the fewest connections between Orlando, FL and St. Louis, MO, with 2 offers.

Facts about the bus from Orlando, FL to St. Louis, MO

Compare all providers like FlixBus that travel 7 times every day by bus from Orlando, FL to St. Louis, MO in one click! Book your bus ticket from Orlando, FL to St. Louis, MO starting from $86!

Cheapest Bus	$86
Fastest Bus	18h 35m
Earliest Bus	2:00 PM
Latest Bus	10:55 PM
Daily Bus Routes	7 Ø
Distance	861.4 miles
Bus Companies	FlixBus

Cheapest bus connections from Orlando, FL to St. Louis, MO

Every day, 7 buses from 1 bus companies leave Orlando, FL for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/03/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/02

Monday 08/03

Tuesday 08/04

$113

Wednesday 08/05

$96

Thursday 08/06

$101

Friday 08/07

$100

Saturday 08/08

$109

Sunday 08/09

$138

Monday 08/10

$102

Tuesday 08/11

$107

Wednesday 08/12

$102

Thursday 08/13

$95

Friday 08/14

$100

Saturday 08/15

$104

Sunday 08/16

Monday 08/17

$103

Tuesday 08/18

$111

Wednesday 08/19

$98

Thursday 08/20

$102

Friday 08/21

$100

Saturday 08/22

Sunday 08/23

$104

Monday 08/24

$89

Tuesday 08/25

$86

Wednesday 08/26

Thursday 08/27

$88

Friday 08/28

Saturday 08/29

The cheapest time to travel from Orlando, FL to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Orlando, FL to St. Louis, MO, for the next 30 days.

With a price starting from $86, Tuesday is the cheapest day for a bus from Orlando, FL to St. Louis, MO. Sunday instead is the most expensive day with prices starting from $104.

Afternoon is the cheapest day time for bus tickets from Orlando, FL to St. Louis, MO, with $96. Morning is the most expensive time of the day with prices starting from $104.

How to save money travelling from Orlando, FL to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Orlando, FL to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Orlando, FL to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Orlando, FL to St. Louis, MO are also emptier.

Beloved bus companies from Orlando, FL to St. Louis, MO

These are the most booked bus companies between Orlando, FL to St. Louis, MO from our users.

FlixBus from Orlando, FL to St. Louis, MO

Here you will find the key facts about the FlixBus bus route Orlando, FL to St. Louis, MO:

Cheapest Price	$96
Fastest Bus	18h 35m
Earliest Bus	2:00 PM
Last Bus	10:55 PM
Daily Connections	7 Ø
Found on	8/1/2026

All bus stations and stops in Orlando, FL and St. Louis, MO

In the map below, you can see where to find all bus stations in Orlando, FL and St. Louis, MO.

Bus Station

N John Young Pkwy 555

Florida Mall

Florida Mall Avenue 1602

RedCoach Station

Belle Isle

Universal Studio Orlando Resort

Universal Blvd 5800

Seaworld Hotels

International Dr 10100

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Service and Comfort on the bus from Orlando, FL to St. Louis, MO

Want to know which seat classes are available on the buses from Orlando, FL to St. Louis, MO? Or which bus companies serve the route Orlando, FL to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Orlando, FL to St. Louis, MO bus

How much does a Orlando, FL St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $86 and takes 19h 20m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Orlando, FL to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $86 and $204. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Orlando, FL to St. Louis, MO each day?

Every day, the Orlando, FL to St. Louis, MO bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Orlando, FL to St. Louis, MO take?

The fastest bus from Orlando, FL to St. Louis, MO is offered by FlixBus and takes 18h 35m. Bus tickets for this connection cost $124. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Orlando, FL to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Orlando, FL starts at 2:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Orlando, FL to St. Louis, MO?

The latest bus trip departing from Orlando, FL for St. Louis, MO starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Orlando, FL St. Louis, MO route?

When traveling by bus from Orlando, FL to St. Louis, MO, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Orlando, FL and St. Louis, MO?

You can check all the direct connections between Orlando, FL and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Orlando, FL to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Orlando, FL St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Orlando, FL St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Orlando, FL to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Orlando, FL to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Orlando, FL and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Orlando, FL to St. Louis, MO?

Prices and availability for 7 trips between Orlando, FL and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Orlando, FL to St. Louis, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Orlando, FL and to St. Louis, MO

Here’s an overview of the most popular bus routes to Orlando, FL and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!