Bus Los Angeles to St. Louis, MO - Compare all Companies

Compare all timetables for the bus from Los Angeles to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Los Angeles to St. Louis, MO from various bus operators like Greyhound US or FlixBus for the next days.

today

$140

tomorrow

Monday

$126

Tuesday

$107

Wednesday

Thursday

$123

Friday

$122

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	40h 55m	6:00 PM	Los Angeles	Union Station	12:55 PM	St. Louis, MO	Gateway Station	Economy	$140	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/20/2026 6:00:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/22/2026 12:55:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 40h 55m
Greyhound US	44h 10m	12:35 AM	Los Angeles	Union Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$141	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/20/2026 12:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 6/21/2026 10:45:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 44h 10m
FlixBus	43h 35m	9:35 AM	Los Angeles	Union Station	7:10 AM	St. Louis, MO	Gateway Station	Economy	$143	A Bus from FlixBus goes from Union Station, Los Angeles (USA) at 6/20/2026 9:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 6/22/2026 7:10:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 43h 35m
FlixBus	55h 25m	1:20 PM	Los Angeles	Union Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$145	A Bus from FlixBus goes from Union Station, Los Angeles (USA) at 6/20/2026 1:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/22/2026 10:45:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 55h 25m
Greyhound US	45h 15m	11:30 PM	Los Angeles	Union Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$147	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/20/2026 11:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/22/2026 10:45:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 45h 15m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	45h 15m	11:30 PM	Los Angeles	Union Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$126	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/22/2026 11:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/24/2026 10:45:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 45h 15m
FlixBus	43h 35m	9:35 AM	Los Angeles	Union Station	7:10 AM	St. Louis, MO	Gateway Station	Economy	$126	A Bus from FlixBus goes from Union Station, Los Angeles (USA) at 6/22/2026 9:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 6/24/2026 7:10:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 43h 35m
Greyhound US	40h 55m	6:00 PM	Los Angeles	Union Station	12:55 PM	St. Louis, MO	Gateway Station	Economy	$128	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/22/2026 6:00:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/24/2026 12:55:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 40h 55m
FlixBus	55h 25m	1:20 PM	Los Angeles	Union Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$128	A Bus from FlixBus goes from Union Station, Los Angeles (USA) at 6/22/2026 1:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/24/2026 10:45:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 55h 25m
Greyhound US	44h 10m	12:35 AM	Los Angeles	Union Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$140	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/22/2026 12:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 6/23/2026 10:45:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 44h 10m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	45h 15m	11:30 PM	Los Angeles	Union Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$107	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/23/2026 11:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/25/2026 10:45:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 45h 15m
Greyhound US	40h 55m	6:00 PM	Los Angeles	Union Station	12:55 PM	St. Louis, MO	Gateway Station	Economy	$109	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/23/2026 6:00:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/25/2026 12:55:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 40h 55m
Greyhound US	43h 50m	3:05 PM	Los Angeles	North Hollywood	12:55 PM	St. Louis, MO	Gateway Station	Economy	$113	A Bus from Greyhound US goes from North Hollywood, Los Angeles (USA) at 6/23/2026 3:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/25/2026 12:55:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 43h 50m
FlixBus	43h 35m	9:35 AM	Los Angeles	Union Station	7:10 AM	St. Louis, MO	Gateway Station	Economy	$121	A Bus from FlixBus goes from Union Station, Los Angeles (USA) at 6/23/2026 9:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 6/25/2026 7:10:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 43h 35m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	55h 25m	1:20 PM	Los Angeles	Union Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$123	A Bus from FlixBus goes from Union Station, Los Angeles (USA) at 6/25/2026 1:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/27/2026 10:45:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 55h 25m
Greyhound US	40h 55m	6:00 PM	Los Angeles	Union Station	12:55 PM	St. Louis, MO	Gateway Station	Economy	$125	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/25/2026 6:00:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/27/2026 12:55:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 40h 55m
Greyhound US	45h 15m	11:30 PM	Los Angeles	Union Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$125	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/25/2026 11:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/27/2026 10:45:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 45h 15m
FlixBus	43h 35m	9:35 AM	Los Angeles	Union Station	7:10 AM	St. Louis, MO	Gateway Station	Economy	$125	A Bus from FlixBus goes from Union Station, Los Angeles (USA) at 6/25/2026 9:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 6/27/2026 7:10:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 43h 35m
Greyhound US	44h 10m	12:35 AM	Los Angeles	Union Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$128	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/25/2026 12:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 6/26/2026 10:45:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 44h 10m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	44h 10m	12:35 AM	Los Angeles	Union Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$122	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/26/2026 12:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 6/27/2026 10:45:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 44h 10m
Greyhound US	40h 55m	6:00 PM	Los Angeles	Union Station	12:55 PM	St. Louis, MO	Gateway Station	Economy	$125	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/26/2026 6:00:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/28/2026 12:55:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 40h 55m
FlixBus	43h 35m	9:35 AM	Los Angeles	Union Station	7:10 AM	St. Louis, MO	Gateway Station	Economy	$125	A Bus from FlixBus goes from Union Station, Los Angeles (USA) at 6/26/2026 9:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 6/28/2026 7:10:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 43h 35m
Greyhound US	45h 15m	11:30 PM	Los Angeles	Union Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$206	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/26/2026 11:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/28/2026 10:45:00 PM. 50 Economy ticket for $206 per person are available. Travel duration is 45h 15m
FlixBus	55h 0m	1:45 PM	Los Angeles	Union Station	10:45 PM	St. Louis, MO	Gateway Station	Economy	$207	A Bus from FlixBus goes from Union Station, Los Angeles (USA) at 6/26/2026 1:45:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/28/2026 10:45:00 PM. 50 Economy ticket for $207 per person are available. Travel duration is 55h 0m

Best Price Offer: The price for the cheapest bus from Los Angeles to St. Louis, MO is $107 on 6/23/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Los Angeles and St. Louis, MO

See here how frequent the connections between Los Angeles and St. Louis, MO are, during different times and days of the week.

Tuesday is the busiest day, with more than 8 daily buses from Los Angeles to St. Louis, MO. Monday has instead the fewest connections, with only 6 daily coaches between Los Angeles and St. Louis, MO.

The busiest time of the day is the Afternoon, with 11 buses from Los Angeles to St. Louis, MO, while Night sees the fewest connections between Los Angeles and St. Louis, MO, with 5 offers.

Facts about the bus from Los Angeles to St. Louis, MO

Compare all providers like Greyhound US and FlixBus that travel 6 times every day by bus from Los Angeles to St. Louis, MO in one click! Book your bus ticket from Los Angeles to St. Louis, MO starting from $107!

Cheapest Bus	$107
Fastest Bus	42h 15m
Earliest Bus	12:35 AM
Latest Bus	11:30 PM
Daily Bus Routes	6 Ø
Distance	1,585.6 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Los Angeles to St. Louis, MO

Every day, 6 buses from 2 bus companies leave Los Angeles for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/14

Monday 06/15

Tuesday 06/16

Wednesday 06/17

Thursday 06/18

Friday 06/19

Saturday 06/20

$140

Sunday 06/21

Monday 06/22

$126

Tuesday 06/23

$107

Wednesday 06/24

Thursday 06/25

$123

Friday 06/26

$122

Saturday 06/27

$118

Sunday 06/28

$113

Monday 06/29

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

Friday 07/03

Saturday 07/04

Sunday 07/05

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

$136

Friday 07/10

Saturday 07/11

The cheapest time to travel from Los Angeles to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Los Angeles to St. Louis, MO, for the next 30 days.

With a price starting from $106, Monday is the cheapest day for a bus from Los Angeles to St. Louis, MO. Friday instead is the most expensive day with prices starting from $122.

Night is the cheapest day time for bus tickets from Los Angeles to St. Louis, MO, with $106. Morning is the most expensive time of the day with prices starting from $121.

How to save money travelling from Los Angeles to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Los Angeles to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Los Angeles to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Los Angeles to St. Louis, MO are also emptier.

Beloved bus companies from Los Angeles to St. Louis, MO

These are the most booked bus companies between Los Angeles to St. Louis, MO from our users.

Greyhound US from Los Angeles to St. Louis, MO

Here you will find the key facts about the Greyhound US bus route Los Angeles to St. Louis, MO:

Cheapest Price	$107
Fastest Bus	42h 15m
Earliest Bus	12:35 AM
Last Bus	11:30 PM
Daily Connections	4 Ø
Found on	5/27/2026

FlixBus from Los Angeles to St. Louis, MO

Here you will find the key facts about the FlixBus bus route Los Angeles to St. Louis, MO:

Cheapest Price	$121
Fastest Bus	45h 35m
Earliest Bus	9:35 AM
Last Bus	1:45 PM
Daily Connections	1 Ø
Found on	5/27/2026

All bus stations and stops in Los Angeles and St. Louis, MO

In the map below, you can see where to find all bus stations in Los Angeles and St. Louis, MO.

Downtown Bus Station

N Main St 512

Las Casas

Main Street 94

Tufesa

Maple Ave 611

Union Station

Ramirez Street 401-479

Amtrak

Alameda Street 738-788

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Service and Comfort on the bus from Los Angeles to St. Louis, MO

Want to know which seat classes are available on the buses from Los Angeles to St. Louis, MO? Or which bus companies serve the route Los Angeles to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Los Angeles to St. Louis, MO bus

How much does a Los Angeles St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $107 and takes 47h 15m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Los Angeles to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $107 and $382. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Los Angeles to St. Louis, MO each day?

Every day, the Los Angeles to St. Louis, MO bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Los Angeles to St. Louis, MO take?

The fastest bus from Los Angeles to St. Louis, MO is offered by Greyhound US and takes 42h 15m. Bus tickets for this connection cost $191. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Los Angeles to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Los Angeles starts at 12:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Los Angeles to St. Louis, MO?

The latest bus trip departing from Los Angeles for St. Louis, MO starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Los Angeles St. Louis, MO route?

When traveling by bus from Los Angeles to St. Louis, MO, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Los Angeles and St. Louis, MO?

You can check all the direct connections between Los Angeles and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Los Angeles to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Los Angeles St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Los Angeles St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Los Angeles to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Los Angeles to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Los Angeles and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Los Angeles to St. Louis, MO?

Prices and availability for 6 trips between Los Angeles and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Los Angeles to St. Louis, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Los Angeles and to St. Louis, MO

Here’s an overview of the most popular bus routes to Los Angeles and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!