Compare all timetables for the bus from Durham, NC to St. Louis, MO
Here is a selection of the cheapest bus trips from the schedule from Durham, NC to St. Louis, MO from various bus operators like Greyhound US or FlixBus for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 24h 50m | 4:05 PM | Durham, NC | Exxon | 3:55 PM | St. Louis, MO | Gateway Station | Economy | $101 |
A Bus from Greyhound US goes from Exxon, Durham, NC (USA) at 6/4/2026 4:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/5/2026 3:55:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 24h 50m
|
||
| Greyhound US | 20h 15m | 2:20 PM | Durham, NC | Exxon | 9:35 AM | St. Louis, MO | Gateway Station | Economy | $102 |
A Bus from Greyhound US goes from Exxon, Durham, NC (USA) at 6/4/2026 2:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/5/2026 9:35:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 20h 15m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 24h 50m | 4:05 PM | Durham, NC | Exxon | 3:55 PM | St. Louis, MO | Gateway Station | Economy | $108 |
A Bus from Greyhound US goes from Exxon, Durham, NC (USA) at 6/6/2026 4:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/7/2026 3:55:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 24h 50m
|
||
| FlixBus | 19h 55m | 2:40 PM | Durham, NC | Exxon | 9:35 AM | St. Louis, MO | Gateway Station | Economy | $109 |
A Bus from FlixBus goes from Exxon, Durham, NC (USA) at 6/6/2026 2:40:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/7/2026 9:35:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 19h 55m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 19h 55m | 2:40 PM | Durham, NC | Chapel Hill and Willard St | 9:35 AM | St. Louis, MO | Gateway Station | Economy | $101 |
A Bus from FlixBus goes from Chapel Hill and Willard St, Durham, NC (USA) at 6/7/2026 2:40:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/8/2026 9:35:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 19h 55m
|
||
| Greyhound US | 24h 50m | 4:05 PM | Durham, NC | Chapel Hill and Willard St | 3:55 PM | St. Louis, MO | Gateway Station | Economy | $101 |
A Bus from Greyhound US goes from Chapel Hill and Willard St, Durham, NC (USA) at 6/7/2026 4:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/8/2026 3:55:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 24h 50m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 19h 55m | 2:40 PM | Durham, NC | Chapel Hill and Willard St | 9:35 AM | St. Louis, MO | Gateway Station | Economy | $99 |
A Bus from FlixBus goes from Chapel Hill and Willard St, Durham, NC (USA) at 6/8/2026 2:40:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/9/2026 9:35:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 19h 55m
|
||
| Greyhound US | 24h 50m | 4:05 PM | Durham, NC | Chapel Hill and Willard St | 3:55 PM | St. Louis, MO | Gateway Station | Economy | $101 |
A Bus from Greyhound US goes from Chapel Hill and Willard St, Durham, NC (USA) at 6/8/2026 4:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/9/2026 3:55:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 24h 50m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 19h 55m | 2:40 PM | Durham, NC | Chapel Hill and Willard St | 9:35 AM | St. Louis, MO | Gateway Station | Economy | $97 |
A Bus from FlixBus goes from Chapel Hill and Willard St, Durham, NC (USA) at 6/9/2026 2:40:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/10/2026 9:35:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 19h 55m
|
||
| Greyhound US | 24h 50m | 4:05 PM | Durham, NC | Chapel Hill and Willard St | 3:55 PM | St. Louis, MO | Gateway Station | Economy | $97 |
A Bus from Greyhound US goes from Chapel Hill and Willard St, Durham, NC (USA) at 6/9/2026 4:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/10/2026 3:55:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 24h 50m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 20h 15m | 2:20 PM | Durham, NC | Chapel Hill and Willard St | 9:35 AM | St. Louis, MO | Gateway Station | Economy | $93 |
A Bus from Greyhound US goes from Chapel Hill and Willard St, Durham, NC (USA) at 6/10/2026 2:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/11/2026 9:35:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 20h 15m
|
||
| Greyhound US | 24h 50m | 4:05 PM | Durham, NC | Chapel Hill and Willard St | 3:55 PM | St. Louis, MO | Gateway Station | Economy | $93 |
A Bus from Greyhound US goes from Chapel Hill and Willard St, Durham, NC (USA) at 6/10/2026 4:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 6/11/2026 3:55:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 24h 50m
|
Best Price Offer: The price for the cheapest bus from Durham, NC to St. Louis, MO is $88 on 6/25/2026. Flexible travelers save on ticket prices.
Facts about the bus from Durham, NC to St. Louis, MO
Compare all providers like Greyhound US and FlixBus that travel 2 times every day by bus from Durham, NC to St. Louis, MO in one click! Book your bus ticket from Durham, NC to St. Louis, MO starting from $88!
| Cheapest Bus | $88 |
| Fastest Bus | 18h 55m |
| Earliest Bus | 2:20 PM |
| Latest Bus | 4:05 PM |
| Daily Bus Routes | 2 Ø |
| Distance | 646.5 miles |
| Bus Companies | Greyhound US and FlixBus |
Cheapest bus connections from Durham, NC to St. Louis, MO
Every day, 2 buses from 2 bus companies leave Durham, NC for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/04/2026 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
05/31
Monday
06/01
Tuesday
06/02
Wednesday
06/03
Thursday
06/04
$101
Friday
06/05
Saturday
06/06
$108
Sunday
06/07
$101
Monday
06/08
$103
Tuesday
06/09
$97
Wednesday
06/10
$93
Thursday
06/11
$93
Friday
06/12
$98
Saturday
06/13
$102
Sunday
06/14
Monday
06/15
Tuesday
06/16
Wednesday
06/17
$99
Thursday
06/18
$97
Friday
06/19
Saturday
06/20
$104
Sunday
06/21
Monday
06/22
$107
Tuesday
06/23
$109
Wednesday
06/24
$90
Thursday
06/25
$88
Friday
06/26
Saturday
06/27
How to save money travelling from Durham, NC to St. Louis, MO
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Durham, NC to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Durham, NC to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Durham, NC to St. Louis, MO are also emptier.Beloved bus companies from Durham, NC to St. Louis, MO
These are the most booked bus companies between Durham, NC to St. Louis, MO from our users.
Greyhound US from Durham, NC to St. Louis, MO
Here you will find the key facts about the Greyhound US bus route Durham, NC to St. Louis, MO:
| Cheapest Price | $93 |
| Fastest Bus | 19h 15m |
| Earliest Bus | 2:20 PM |
| Last Bus | 4:05 PM |
| Daily Connections | 1 Ø |
| Found on | 5/11/2026 |
All bus stations and stops in Durham, NC and St. Louis, MO
In the map below, you can see where to find all bus stations in Durham, NC and St. Louis, MO.
Service and Comfort on the bus from Durham, NC to St. Louis, MO
Want to know which seat classes are available on the buses from Durham, NC to St. Louis, MO? Or which bus companies serve the route Durham, NC to St. Louis, MO? Below you will find answers to your questions.
FAQs about the Durham, NC to St. Louis, MO bus
How much does a Durham, NC St. Louis, MO bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $88 and takes 19h 15m to reach St. Louis, MO. Compare offers to save money!
How much could I save by comparing buses from Durham, NC to St. Louis, MO?
This route is offered by 2 companies with a range of ticket prices between $88 and $109. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.
On average, how many connections are available from Durham, NC to St. Louis, MO each day?
Every day, the Durham, NC to St. Louis, MO bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Durham, NC to St. Louis, MO take?
The fastest bus from Durham, NC to St. Louis, MO is offered by FlixBus and takes 18h 55m. Bus tickets for this connection cost $109. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Durham, NC to St. Louis, MO?
The earliest bus arriving in St. Louis, MO from Durham, NC starts at 2:20 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Durham, NC to St. Louis, MO?
The latest bus trip departing from Durham, NC for St. Louis, MO starts at 4:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Durham, NC St. Louis, MO route?
When traveling by bus from Durham, NC to St. Louis, MO, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Durham, NC and St. Louis, MO?
You can check all the direct connections between Durham, NC and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.
What can I take with me on the Durham, NC to St. Louis, MO bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Durham, NC St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Durham, NC St. Louis, MO bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Durham, NC to St. Louis, MO on your planned travel date.
How does CheckMyBus find the best bus deals from Durham, NC to St. Louis, MO?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Durham, NC and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Durham, NC to St. Louis, MO?
Prices and availability for 2 trips between Durham, NC and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Durham, NC to St. Louis, MO
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Durham, NC and to St. Louis, MO
Here’s an overview of the most popular bus routes to Durham, NC and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Durham, NC
- Bus Albany, GA to Durham, NC
- Buses from Atlanta, GA to Durham, NC
- Bridgeport, CT to Durham, NC bus
- Buses Charleston, SC - Durham, NC
- Bus to Durham, NC from Charlotte
- Bus Columbia, SC - Durham, NC
- Bus from Fayetteville, NC to Durham, NC
- Bus from Flint, MI to Durham, NC
- Bus from Greensboro, NC to Durham, NC
- Greenville, NC to Durham, NC bus
- Buses Lawton, OK to Durham, NC
- Bus Myrtle Beach, SC to Durham, NC
- Bus from New York to Durham, NC
- Buses Opelika, AL to Durham, NC
- Buses from Richmond, VA to Durham, NC
- Buses Springfield, MA - Durham, NC
- Buses from Washington, DC to Durham, NC
- From Wilmington, DE to Durham, NC bus
- Bus Routes to St. Louis, MO
- Buses to St. Louis, MO from Abilene, TX
- Buses Carbondale, IL - St. Louis, MO
- Bus from Chicago to St. Louis, MO
- Buses Cincinnati - St. Louis, MO
- Bus from College Park, MD to St. Louis, MO
- Columbia, MO to St. Louis, MO bus
- Buses Columbus, OH - St. Louis, MO
- From Dallas to St. Louis, MO bus
- Bus Houston - St. Louis, MO
- Buses Jackson, TN - St. Louis, MO
- Bus from Jacksonville, FL to St. Louis, MO
- Bus Los Angeles to St. Louis, MO
- Buses Mansfield, OH - St. Louis, MO
- Bus from Oklahoma City, OK to St. Louis, MO
- Bus Phoenix, AZ to St. Louis, MO
- From San Antonio, TX to St. Louis, MO bus
- Buses to St. Louis, MO from Springfield, MO
- Buses Temple, TX - St. Louis, MO
- Buses Toledo, OH to St. Louis, MO
- Bus to St. Louis, MO from Windsor, ON
Popular Airport Shuttles to Durham, NC and to St. Louis, MO
