Bus from Knoxville, TN to Durham, NC from $107

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Compare all timetables for the bus from Knoxville, TN to Durham, NC

Here is a selection of the cheapest bus trips from the schedule from Knoxville, TN to Durham, NC from various bus operators like Greyhound US for the next days.

today
tomorrow
$179
Sunday
$107
Monday
Tuesday
$190
Wednesday
Thursday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 13h 20m 7:40 PM Knoxville, TN Greyhound Bus Station 9:00 AM Durham, NC Exxon  Economy $179

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 13h 20m 7:40 PM Knoxville, TN Greyhound Bus Station 9:00 AM Durham, NC Exxon  Economy $107
  • Did you know that if you travel from Knoxville, TN to Durham, NC via Atlanta, GA, you can save more than $13? You can find the corresponding connections below.
    • FlixBus
      13h 20m
      0
      7:40 PM
      Knoxville, TN
      Greyhound Bus Station
      11:35 PM
      Atlanta, GA
      Garnett Transit Station
      0
      FlixBus
      Economy
      $36
      • Waiting Time 1h 5m
    • FlixBus
      8h 20m
      0
      12:40 AM
      Atlanta, GA
      Garnett Transit Station
      9:00 AM
      Durham, NC
      Exxon
      0
      FlixBus
      Economy
      $58
    Travel time is the same as the direct connection, but you will save $13

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 13h 20m 7:40 PM Knoxville, TN Greyhound Bus Station 9:00 AM Durham, NC Exxon  Economy $190
  • Did you know that if you travel from Knoxville, TN to Durham, NC via Atlanta, GA, you can save more than $96? You can find the corresponding connections below.
    • FlixBus
      13h 20m
      0
      7:40 PM
      Knoxville, TN
      Greyhound Bus Station
      11:35 PM
      Atlanta, GA
      Garnett Transit Station
      0
      FlixBus
      Economy
      $36
      • Waiting Time 1h 5m
    • FlixBus
      8h 20m
      0
      12:40 AM
      Atlanta, GA
      Garnett Transit Station
      9:00 AM
      Durham, NC
      Exxon
      0
      FlixBus
      Economy
      $58
    Travel time is the same as the direct connection, but you will save $96

Best Price Offer: The price for the cheapest bus from Knoxville, TN to Durham, NC is $107 on 2/8/2026. Flexible travelers save on ticket prices.


Facts about the bus from Knoxville, TN to Durham, NC

Compare all providers like Greyhound US that travel 1 times every day by bus from Knoxville, TN to Durham, NC in one click! Book your bus ticket from Knoxville, TN to Durham, NC starting from $107!

Cheapest Bus $107
Fastest Bus 13h 20m
Earliest Bus 7:40 PM
Latest Bus 7:40 PM
Daily Bus Routes 1 Ø
Distance 280.0 miles
Bus Companies Greyhound US

Cheapest bus connections from Knoxville, TN to Durham, NC

Every day, 1 buses from 1 bus companies leave Knoxville, TN for Durham, NC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/06/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/01
Monday 02/02
Tuesday 02/03
Wednesday 02/04
Thursday 02/05
Friday 02/06
Saturday 02/07
$179
Sunday 02/08
$107
Monday 02/09
Tuesday 02/10
$190
Wednesday 02/11
Thursday 02/12
Friday 02/13
Saturday 02/14
Sunday 02/15
Monday 02/16
Tuesday 02/17
Wednesday 02/18
Thursday 02/19
Friday 02/20
Saturday 02/21
Sunday 02/22
Monday 02/23
Tuesday 02/24
Wednesday 02/25
Thursday 02/26
Friday 02/27
Saturday 02/28

How to save money travelling from Knoxville, TN to Durham, NC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Knoxville, TN to Durham, NC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Knoxville, TN to Durham, NC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Knoxville, TN to Durham, NC are also emptier.

All bus stations and stops in Knoxville, TN and Durham, NC

In the map below, you can see where to find all bus stations in Knoxville, TN and Durham, NC.

Service and Comfort on the bus from Knoxville, TN to Durham, NC

Want to know which seat classes are available on the buses from Knoxville, TN to Durham, NC? Or which bus companies serve the route Knoxville, TN to Durham, NC? Below you will find answers to your questions.

FAQs about the Knoxville, TN to Durham, NC bus

How much does a Knoxville, TN Durham, NC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $107 and takes 13h 20m to reach Durham, NC. Compare offers to save money!

How much could I save by comparing buses from Knoxville, TN to Durham, NC?

This route is offered by 1 companies with a range of ticket prices between $107 and $190. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Durham, NC.

On average, how many connections are available from Knoxville, TN to Durham, NC each day?

Every day, the Knoxville, TN to Durham, NC bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Knoxville, TN to Durham, NC take?

The fastest bus from Knoxville, TN to Durham, NC is offered by Greyhound US and takes 13h 20m. Bus tickets for this connection cost $179. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Knoxville, TN to Durham, NC?

The earliest bus arriving in Durham, NC from Knoxville, TN starts at 7:40 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Knoxville, TN to Durham, NC?

The latest bus trip departing from Knoxville, TN for Durham, NC starts at 7:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Knoxville, TN Durham, NC route?

When traveling by bus from Knoxville, TN to Durham, NC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Knoxville, TN and Durham, NC?

You can check all the direct connections between Knoxville, TN and Durham, NC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Knoxville, TN to Durham, NC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Knoxville, TN Durham, NC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Knoxville, TN Durham, NC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Knoxville, TN to Durham, NC on your planned travel date.

How does CheckMyBus find the best bus deals from Knoxville, TN to Durham, NC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Knoxville, TN and Durham, NC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Knoxville, TN to Durham, NC?

Prices and availability for 1 trips between Knoxville, TN and Durham, NC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Knoxville, TN to Durham, NC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Knoxville, TN and to Durham, NC

Here’s an overview of the most popular bus routes to Knoxville, TN and to Durham, NC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Knoxville, TN and to Durham, NC
CheckMyBus › Buses in USA › Bus to Knoxville, TN › Bus to Durham, NC

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