Bus from Florence, SC to Durham, NC from $42

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Compare all timetables for the bus from Florence, SC to Durham, NC

Here is a selection of the cheapest bus trips from the schedule from Florence, SC to Durham, NC from various bus operators like Wanda Coach or FlixBus for the next days.

today
$59
tomorrow
$44
Saturday
$59
Sunday
Monday
$59
Tuesday
$59
Wednesday
$59

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Wanda Coach 3h 30m 7:00 PM Florence, SC Exxon Gas Station 10:30 PM Durham, NC BP Guess Road  Economy $59
Wanda Coach 3h 30m 9:00 PM Florence, SC Exxon Gas Station 12:30 AM Durham, NC BP Guess Road  Economy $59

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 4h 45m 12:05 AM Florence, SC TA Travel Center 4:50 AM Durham, NC Exxon  Economy $44
Wanda Coach 3h 30m 7:00 PM Florence, SC Exxon Gas Station 10:30 PM Durham, NC BP Guess Road  Economy $59
Wanda Coach 3h 30m 9:00 PM Florence, SC Exxon Gas Station 12:30 AM Durham, NC BP Guess Road  Economy $59

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Wanda Coach 3h 30m 7:00 PM Florence, SC Exxon Gas Station 10:30 PM Durham, NC BP Guess Road  Economy $59
Wanda Coach 3h 30m 9:00 PM Florence, SC Exxon Gas Station 12:30 AM Durham, NC BP Guess Road  Economy $59
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $14? You can find the corresponding connections below.
    • FlixBus
      4h 45m
      0
      12:05 AM
      Florence, SC
      TA Travel Center
      2:45 AM
      Raleigh, NC
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $40
      • Waiting Time 1h 30m
    • Greyhound US
      0h 35m
      0
      4:15 AM
      Raleigh, NC
      Greyhound Bus Station
      4:50 AM
      Durham, NC
      Chapel Hill and Willard St
      0
      Greyhound US
      Economy
      $5
    Travel time is 1h 15m longer, but you will save $14

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Wanda Coach 3h 30m 7:00 PM Florence, SC Exxon Gas Station 10:30 PM Durham, NC BP Guess Road  Economy $59
Wanda Coach 3h 30m 9:00 PM Florence, SC Exxon Gas Station 12:30 AM Durham, NC BP Guess Road  Economy $59
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $14? You can find the corresponding connections below.
    • FlixBus
      4h 45m
      0
      12:05 AM
      Florence, SC
      TA Travel Center
      2:45 AM
      Raleigh, NC
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $40
      • Waiting Time 1h 30m
    • Greyhound US
      0h 35m
      0
      4:15 AM
      Raleigh, NC
      Greyhound Bus Station
      4:50 AM
      Durham, NC
      Chapel Hill and Willard St
      0
      Greyhound US
      Economy
      $5
    Travel time is 1h 15m longer, but you will save $14

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Wanda Coach 3h 30m 7:00 PM Florence, SC Exxon Gas Station 10:30 PM Durham, NC BP Guess Road  Economy $59
Wanda Coach 3h 30m 9:00 PM Florence, SC Exxon Gas Station 12:30 AM Durham, NC BP Guess Road  Economy $59
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $14? You can find the corresponding connections below.
    • FlixBus
      4h 45m
      0
      12:05 AM
      Florence, SC
      TA Travel Center
      2:45 AM
      Raleigh, NC
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $40
      • Waiting Time 1h 30m
    • Greyhound US
      0h 35m
      0
      4:15 AM
      Raleigh, NC
      Greyhound Bus Station
      4:50 AM
      Durham, NC
      Chapel Hill and Willard St
      0
      Greyhound US
      Economy
      $5
    Travel time is 1h 15m longer, but you will save $14

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Wanda Coach 3h 30m 7:00 PM Florence, SC Exxon Gas Station 10:30 PM Durham, NC BP Guess Road  Economy $59
Wanda Coach 3h 30m 9:00 PM Florence, SC Exxon Gas Station 12:30 AM Durham, NC BP Guess Road  Economy $59
  • Did you know that if you travel from Florence, SC to Durham, NC via Raleigh, NC, you can save more than $14? You can find the corresponding connections below.
    • Wanda Coach
      4h 30m
      0
      9:00 PM
      Florence, SC
      Shell Gas Station
      11:45 PM
      Raleigh, NC
      Nottingham Dr at Buck Jones Rd (EB)
      0
      Wanda Coach
      Economy
      $40
      • Waiting Time 1h 10m
    • Greyhound US
      0h 35m
      0
      12:55 AM
      Raleigh, NC
      Greyhound Bus Station
      1:30 AM
      Durham, NC
      Chapel Hill and Willard St
      0
      Greyhound US
      Economy
      $5
    Travel time is 1h 0m longer, but you will save $14

Best Price Offer: The price for the cheapest bus from Florence, SC to Durham, NC is $42 on 11/7/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Florence, SC and Durham, NC

See here how frequent the connections between Florence, SC and Durham, NC are, during different times and days of the week.
Friday is the busiest day, with more than 5 daily buses from Florence, SC to Durham, NC. Monday has instead the fewest connections, with only 4 daily coaches between Florence, SC and Durham, NC.
The busiest time of the day is the Evening, with 24 buses from Florence, SC to Durham, NC, while Night sees the fewest connections between Florence, SC and Durham, NC, with 1 offers.

Facts about the bus from Florence, SC to Durham, NC

Compare all providers like Wanda Coach and FlixBus that travel 4 times every day by bus from Florence, SC to Durham, NC in one click! Book your bus ticket from Florence, SC to Durham, NC starting from $42!

Cheapest Bus $42
Fastest Bus 3h 30m
Earliest Bus 7:00 PM
Latest Bus 9:00 PM
Daily Bus Routes 4 Ø
Distance 133.6 miles
Bus Companies Wanda Coach and FlixBus

Cheapest bus connections from Florence, SC to Durham, NC

Every day, 4 buses from 2 bus companies leave Florence, SC for Durham, NC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/29/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 10/25
Monday 10/26
Tuesday 10/27
Wednesday 10/28
Thursday 10/29
$59
Friday 10/30
$60
Saturday 10/31
$59
Sunday 11/01
Monday 11/02
$59
Tuesday 11/03
$60
Wednesday 11/04
$60
Thursday 11/05
$59
Friday 11/06
$54
Saturday 11/07
$42
Sunday 11/08
$60
Monday 11/09
$59
Tuesday 11/10
$59
Wednesday 11/11
$59
Thursday 11/12
$60
Friday 11/13
Saturday 11/14
$59
Sunday 11/15
$60
Monday 11/16
$64
Tuesday 11/17
$59
Wednesday 11/18
$59
Thursday 11/19
$59
Friday 11/20
$60
Saturday 11/21

The cheapest time to travel from Florence, SC to Durham, NC

See here on which day and which time of the day you can find the cheapest bus ticket from Florence, SC to Durham, NC, for the next 30 days.
With a price starting from $42, Saturday is the cheapest day for a bus from Florence, SC to Durham, NC. Monday instead is the most expensive day with prices starting from $59.
Night is the cheapest day time for bus tickets from Florence, SC to Durham, NC, with $42. Evening is the most expensive time of the day with prices starting from $59.

How to save money travelling from Florence, SC to Durham, NC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Florence, SC to Durham, NC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Florence, SC to Durham, NC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Florence, SC to Durham, NC are also emptier.

All bus stations and stops in Florence, SC and Durham, NC

In the map below, you can see where to find all bus stations in Florence, SC and Durham, NC.

Service and Comfort on the bus from Florence, SC to Durham, NC

Want to know which seat classes are available on the buses from Florence, SC to Durham, NC? Or which bus companies serve the route Florence, SC to Durham, NC? Below you will find answers to your questions.

FAQs about the Florence, SC to Durham, NC bus

How much does a Florence, SC Durham, NC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $42 and takes 4h 45m to reach Durham, NC. Compare offers to save money!

How much could I save by comparing buses from Florence, SC to Durham, NC?

This route is offered by 2 companies with a range of ticket prices between $42 and $60. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Durham, NC.

On average, how many connections are available from Florence, SC to Durham, NC each day?

Every day, the Florence, SC to Durham, NC bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Florence, SC to Durham, NC take?

The fastest bus from Florence, SC to Durham, NC is offered by Wanda Coach and takes 3h 30m. Bus tickets for this connection cost $60. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Florence, SC to Durham, NC?

The earliest bus arriving in Durham, NC from Florence, SC starts at 7:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Florence, SC to Durham, NC?

The latest bus trip departing from Florence, SC for Durham, NC starts at 9:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Florence, SC Durham, NC route?

When traveling by bus from Florence, SC to Durham, NC, passengers can travel with Wanda Coach and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Florence, SC and Durham, NC?

You can check all the direct connections between Florence, SC and Durham, NC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Wanda Coach and FlixBus.

What can I take with me on the Florence, SC to Durham, NC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Florence, SC Durham, NC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Florence, SC Durham, NC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Florence, SC to Durham, NC on your planned travel date.

How does CheckMyBus find the best bus deals from Florence, SC to Durham, NC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Florence, SC and Durham, NC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Florence, SC to Durham, NC?

Prices and availability for 4 trips between Florence, SC and Durham, NC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Florence, SC to Durham, NC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Florence, SC and to Durham, NC

Here’s an overview of the most popular bus routes to Florence, SC and to Durham, NC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Florence, SC and to Durham, NC
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