Bus from San Diego to Indianapolis from $192

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Compare all timetables for the bus from San Diego to Indianapolis

Here is a selection of the cheapest bus trips from the schedule from San Diego to Indianapolis from various bus operators like FlixBus or Greyhound US for the next days.

today
tomorrow
Saturday
Sunday
$211
Monday
Tuesday
$282
Wednesday

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 54h 10m 7:35 PM San Diego Old Town Transit Center 4:45 AM Indianapolis Central Bus Station  Economy $211
FlixBus 52h 5m 12:15 PM San Diego Old Town Transit Center 7:20 PM Indianapolis Central Bus Station  Economy $212
Greyhound US 49h 30m 10:00 AM San Diego Old Town Transit Center 2:30 PM Indianapolis Central Bus Station  Economy $212
FlixBus 51h 55m 7:35 AM San Diego Old Town Transit Center 2:30 PM Indianapolis Central Bus Station  Economy $213
FlixBus 51h 35m 7:55 AM San Diego La Jolla Village 2:30 PM Indianapolis Central Bus Station  Economy $213

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 54h 10m 7:35 PM San Diego Old Town Transit Center 4:45 AM Indianapolis Central Bus Station  Economy $282
Greyhound US 57h 50m 7:35 PM San Diego Old Town Transit Center 8:25 AM Indianapolis Washington / Delaware  Economy $284
FlixBus 55h 10m 1:10 PM San Diego Seaport Village 11:20 PM Indianapolis Washington / Delaware  Economy $296
Greyhound US 61h 35m 6:45 AM San Diego Old Town Transit Center 11:20 PM Indianapolis Washington / Delaware  Economy $297
FlixBus 58h 55m 9:25 AM San Diego Old Town Transit Center 11:20 PM Indianapolis Washington / Delaware  Economy $297
  • Did you know that if you travel from San Diego to Indianapolis via Phoenix, AZ, you can save more than $66? You can find the corresponding connections below.
    • Busbud
      49h 30m
      0
      10:00 AM
      San Diego
      Old Town Transit Center
      6:15 PM
      Phoenix, AZ
      Bus Station
      0
      Busbud
      Economy
      $40
      • Waiting Time 5h 30m
    • FlixBus
      36h 45m
      0
      11:45 PM
      Phoenix, AZ
      Bus Station
      2:30 PM
      Indianapolis
      Central Bus Station
      0
      FlixBus
      Economy
      $175
    Travel Time is 7h 40m shorter, and you will save $66

Best Price Offer: The price for the cheapest bus from San Diego to Indianapolis is $192 on 1/26/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between San Diego and Indianapolis

See here how frequent the connections between San Diego and Indianapolis are, during different times and days of the week.
Sunday is the busiest day, with more than 15 daily buses from San Diego to Indianapolis. Tuesday has instead the fewest connections, with only 12 daily coaches between San Diego and Indianapolis.
The busiest time of the day is the Morning, with 12 buses from San Diego to Indianapolis, while Evening sees the fewest connections between San Diego and Indianapolis, with 4 offers.

Facts about the bus from San Diego to Indianapolis

Compare all providers like FlixBus and Greyhound US that travel 13 times every day by bus from San Diego to Indianapolis in one click! Book your bus ticket from San Diego to Indianapolis starting from $192!

Cheapest Bus $192
Fastest Bus 52h 30m
Earliest Bus 7:35 AM
Latest Bus 7:35 PM
Daily Bus Routes 13 Ø
Distance 1,785.2 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from San Diego to Indianapolis

Every day, 13 buses from 2 bus companies leave San Diego for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/29/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 01/25
Monday 01/26
Tuesday 01/27
Wednesday 01/28
Thursday 01/29
Friday 01/30
Saturday 01/31
Sunday 02/01
$211
Monday 02/02
Tuesday 02/03
$282
Wednesday 02/04
Thursday 02/05
$207
Friday 02/06
Saturday 02/07
Sunday 02/08
Monday 02/09
Tuesday 02/10
Wednesday 02/11
Thursday 02/12
Friday 02/13
Saturday 02/14
Sunday 02/15
Monday 02/16
Tuesday 02/17
Wednesday 02/18
Thursday 02/19
Friday 02/20
Saturday 02/21

The cheapest time to travel from San Diego to Indianapolis

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to Indianapolis, for the next 30 days.
With a price starting from $211, Sunday is the cheapest day for a bus from San Diego to Indianapolis. Tuesday instead is the most expensive day with prices starting from $282.
Evening is the cheapest day time for bus tickets from San Diego to Indianapolis, with $211. Morning is the most expensive time of the day with prices starting from $212.

How to save money travelling from San Diego to Indianapolis

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to Indianapolis are also emptier.

All bus stations and stops in San Diego and Indianapolis

In the map below, you can see where to find all bus stations in San Diego and Indianapolis.

Service and Comfort on the bus from San Diego to Indianapolis

Want to know which seat classes are available on the buses from San Diego to Indianapolis? Or which bus companies serve the route San Diego to Indianapolis? Below you will find answers to your questions.

FAQs about the San Diego to Indianapolis bus

How much does a San Diego Indianapolis bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $192 and takes 57h 10m to reach Indianapolis. Compare offers to save money!

How much could I save by comparing buses from San Diego to Indianapolis?

This route is offered by 2 companies with a range of ticket prices between $192 and $308. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.

On average, how many connections are available from San Diego to Indianapolis each day?

Every day, the San Diego to Indianapolis bus route is served by approximately 13 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Diego to Indianapolis take?

The fastest bus from San Diego to Indianapolis is offered by Greyhound US and takes 52h 30m. Bus tickets for this connection cost $212. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Diego to Indianapolis?

The earliest bus arriving in Indianapolis from San Diego starts at 7:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Diego to Indianapolis?

The latest bus trip departing from San Diego for Indianapolis starts at 7:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Diego Indianapolis route?

When traveling by bus from San Diego to Indianapolis, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Diego and Indianapolis?

You can check all the direct connections between San Diego and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the San Diego to Indianapolis bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Diego Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego Indianapolis bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to Indianapolis on your planned travel date.

How does CheckMyBus find the best bus deals from San Diego to Indianapolis?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 13 daily trips between San Diego and Indianapolis. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Diego to Indianapolis?

Prices and availability for 13 trips between San Diego and Indianapolis change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Diego to Indianapolis

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to Indianapolis

Here’s an overview of the most popular bus routes to San Diego and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to San Diego and to Indianapolis
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