Compare all timetables for the bus from Las Cruces, NM to San Diego
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 24h 45m | 10:50 AM | Las Cruces, NM | Mesilla Valley Intermodal Transit Terminal | 10:35 AM | San Diego | San Ysidro Transit Center | Economy | $160 |
A Bus from Greyhound US goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/7/2026 10:50:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 2/8/2026 10:35:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 24h 45m
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| Greyhound US | 21h 40m | 6:00 PM | Las Cruces, NM | Mesilla Valley Intermodal Transit Terminal | 2:40 PM | San Diego | San Ysidro Transit Center | Economy | $160 |
A Bus from Greyhound US goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/7/2026 6:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/8/2026 2:40:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 21h 40m
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| Greyhound US | 26h 55m | 3:50 PM | Las Cruces, NM | Mesilla Valley Intermodal Transit Terminal | 5:45 PM | San Diego | Old Town Transit Center | Economy | $164 |
A Bus from Greyhound US goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/7/2026 3:50:00 PM to Old Town Transit Center, San Diego (USA) arriving at 2/8/2026 5:45:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 26h 55m
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| Greyhound US | 20h 40m | 6:00 PM | Las Cruces, NM | Mesilla Valley Intermodal Transit Terminal | 1:40 PM | San Diego | La Jolla Village | Economy | $164 |
A Bus from Greyhound US goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/7/2026 6:00:00 PM to La Jolla Village, San Diego (USA) arriving at 2/8/2026 1:40:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 20h 40m
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| Greyhound US | 25h 55m | 10:50 AM | Las Cruces, NM | Mesilla Valley Intermodal Transit Terminal | 11:45 AM | San Diego | Old Town Transit Center | Economy | $165 |
A Bus from Greyhound US goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/7/2026 10:50:00 AM to Old Town Transit Center, San Diego (USA) arriving at 2/8/2026 11:45:00 AM. 50 Economy ticket for $165 per person are available. Travel duration is 25h 55m
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FlixBus24h 45m06:00 PMLas Cruces, NMMesilla Valley Intermodal Transit Terminal1:05 AMPhoenix, AZBus Station0EconomyA Bus from FlixBus goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/8/2026 6:00:00 PM to Bus Station, Phoenix, AZ (USA) arriving at 2/9/2026 1:05:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 7h 5m
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Busbud7h 45m011:00 AMPhoenix, AZBus Station5:45 PMSan DiegoOld Town Transit Center0EconomyA Bus from Busbud goes from Bus Station, Phoenix, AZ (USA) at 2/9/2026 11:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 2/9/2026 5:45:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 7h 45m
Waiting Time 9h 55m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 21h 40m | 6:00 PM | Las Cruces, NM | Mesilla Valley Intermodal Transit Terminal | 2:40 PM | San Diego | San Ysidro Transit Center | Economy | $142 |
A Bus from Greyhound US goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/11/2026 6:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/12/2026 2:40:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 21h 40m
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| Greyhound US | 24h 10m | 6:00 PM | Las Cruces, NM | Mesilla Valley Intermodal Transit Terminal | 5:10 PM | San Diego | San Ysidro Transit Center | Economy | $142 |
A Bus from Greyhound US goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/11/2026 6:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/12/2026 5:10:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 24h 10m
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| Greyhound US | 26h 30m | 10:50 AM | Las Cruces, NM | Mesilla Valley Intermodal Transit Terminal | 12:20 PM | San Diego | San Ysidro Transit Center | Economy | $144 |
A Bus from Greyhound US goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/11/2026 10:50:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 2/12/2026 12:20:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 26h 30m
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FlixBus24h 45m06:00 PMLas Cruces, NMMesilla Valley Intermodal Transit Terminal1:05 AMPhoenix, AZBus Station0EconomyA Bus from FlixBus goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/8/2026 6:00:00 PM to Bus Station, Phoenix, AZ (USA) arriving at 2/9/2026 1:05:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 7h 5m
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Busbud7h 45m011:00 AMPhoenix, AZBus Station5:45 PMSan DiegoOld Town Transit Center0EconomyA Bus from Busbud goes from Bus Station, Phoenix, AZ (USA) at 2/9/2026 11:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 2/9/2026 5:45:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 7h 45m
Waiting Time 9h 55m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 25h 55m | 10:50 AM | Las Cruces, NM | Mesilla Valley Intermodal Transit Terminal | 11:45 AM | San Diego | Old Town Transit Center | Economy | $95 |
A Bus from Greyhound US goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/12/2026 10:50:00 AM to Old Town Transit Center, San Diego (USA) arriving at 2/13/2026 11:45:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 25h 55m
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| Greyhound US | 26h 55m | 3:50 PM | Las Cruces, NM | Mesilla Valley Intermodal Transit Terminal | 5:45 PM | San Diego | Old Town Transit Center | Economy | $95 |
A Bus from Greyhound US goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/12/2026 3:50:00 PM to Old Town Transit Center, San Diego (USA) arriving at 2/13/2026 5:45:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 26h 55m
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| Greyhound US | 24h 15m | 10:50 AM | Las Cruces, NM | Mesilla Valley Intermodal Transit Terminal | 10:05 AM | San Diego | Seaport Village | Economy | $96 |
A Bus from Greyhound US goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/12/2026 10:50:00 AM to Seaport Village, San Diego (USA) arriving at 2/13/2026 10:05:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 24h 15m
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| Limousine Express | 23h 0m | 11:00 AM | Las Cruces, NM | Mesilla Valley Intermodal Transit Terminal | 9:00 AM | San Diego | San Ysidro Transit Center | Basic | $127 |
A Bus from Limousine Express goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/12/2026 11:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 2/13/2026 9:00:00 AM. 50 Basic ticket for $127 per person are available. Travel duration is 23h 0m
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| Limousine Express | 19h 30m | 11:00 AM | Las Cruces, NM | Mesilla Valley Intermodal Transit Terminal | 5:30 AM | San Diego | San Ysidro Transit Center | Basic | $127 |
A Bus from Limousine Express goes from Mesilla Valley Intermodal Transit Terminal, Las Cruces, NM (USA) at 2/12/2026 11:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 2/13/2026 5:30:00 AM. 50 Basic ticket for $127 per person are available. Travel duration is 19h 30m
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Best Price Offer: The price for the cheapest bus from Las Cruces, NM to San Diego is $95 on 2/5/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Las Cruces, NM and San Diego
Facts about the bus from Las Cruces, NM to San Diego
Compare all providers like Greyhound US and Limousine Express that travel 10 times every day by bus from Las Cruces, NM to San Diego in one click! Book your bus ticket from Las Cruces, NM to San Diego starting from $95!
| Cheapest Bus | $95 |
| Fastest Bus | 16h 30m |
| Earliest Bus | 10:50 AM |
| Latest Bus | 8:15 PM |
| Daily Bus Routes | 10 Ø |
| Distance | 605.8 miles |
| Bus Companies | Greyhound US and Limousine Express |
Cheapest bus connections from Las Cruces, NM to San Diego
Every day, 10 buses from 2 bus companies leave Las Cruces, NM for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/06/2026 and for the following days.
The cheapest time to travel from Las Cruces, NM to San Diego
How to save money travelling from Las Cruces, NM to San Diego
Book the ticket from Las Cruces, NM to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Las Cruces, NM to San Diego, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Las Cruces, NM to San Diego are also emptier.All bus stations and stops in Las Cruces, NM and San Diego
In the map below, you can see where to find all bus stations in Las Cruces, NM and San Diego.
Service and Comfort on the bus from Las Cruces, NM to San Diego
FAQs about the Las Cruces, NM to San Diego bus
How much does a Las Cruces, NM San Diego bus trip cost?
How much could I save by comparing buses from Las Cruces, NM to San Diego?
On average, how many connections are available from Las Cruces, NM to San Diego each day?
How long does a bus journey from Las Cruces, NM to San Diego take?
What time is the first bus from Las Cruces, NM to San Diego?
What time is the last bus from Las Cruces, NM to San Diego?
Which bus companies operate the Las Cruces, NM San Diego route?
Is there a direct bus between Las Cruces, NM and San Diego?
What can I take with me on the Las Cruces, NM to San Diego bus route?
What equipment is available for the Las Cruces, NM San Diego bus route?
How does CheckMyBus find the best bus deals from Las Cruces, NM to San Diego?
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Available seat classes which are offered on the bus route Las Cruces, NM to San Diego
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Las Cruces, NM and to San Diego
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