Which bus from Mexico City to San Diego is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $218
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Compare all timetables for the bus from Mexico City to San Diego

Here is a selection of the cheapest bus trips from the schedule from Mexico City to San Diego from various bus operators like Flix Mexico for the next days.

today
$221
tomorrow
$225
Friday
$244
Saturday
$255
Sunday
$257
Monday
$219
Tuesday
$220

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 66h 0m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:40 PM San Diego San Ysidro Transit Center  Economy $221
Flix Mexico 65h 35m 11:05 PM Mexico City Fórum Buenavista 2:40 PM San Diego San Ysidro Transit Center  Economy $221
Flix Mexico 72h 40m 11:55 AM Mexico City San Pedro Santa Clara Bus Stop 10:35 AM San Diego San Ysidro Transit Center  Economy $270
Flix Mexico 72h 15m 12:20 PM Mexico City Fórum Buenavista 10:35 AM San Diego San Ysidro Transit Center  Economy $270
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $34? You can find the corresponding connections below.
    • ClickBus MX
      43h 54m
      0
      9:01 PM
      Mexico City
      Norte Bus Station
      11:58 AM
      Tijuana, BC
      Centro Bus Stop
      0
      ClickBus MX
      Economy
      $181
      • Waiting Time 1h 12m
    • FlixBus
      1h 45m
      0
      1:10 PM
      Tijuana, BC
      Central Bus Station
      2:55 PM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $6
    Travel Time is 19h 41m shorter, and you will save $34

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 65h 30m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:10 PM San Diego Old Town Transit Center  Economy $225
Flix Mexico 65h 5m 11:05 PM Mexico City Fórum Buenavista 2:10 PM San Diego Old Town Transit Center  Economy $225
Flix Mexico 68h 35m 4:00 PM Mexico City San Pedro Santa Clara Bus Stop 10:35 AM San Diego San Ysidro Transit Center  Economy $277
Flix Mexico 68h 10m 4:25 PM Mexico City Fórum Buenavista 10:35 AM San Diego San Ysidro Transit Center  Economy $277
Flix Mexico 66h 0m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:40 PM San Diego San Ysidro Transit Center  Economy $289
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $71? You can find the corresponding connections below.
    • Busbud
      46h 0m
      0
      10:30 PM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      3:33 PM
      Tijuana, BC
      Centro Bus Stop
      0
      Busbud
      Economy
      $148
      • Waiting Time 1h 27m
    • FlixBus
      1h 30m
      0
      5:00 PM
      Tijuana, BC
      Central Bus Station
      6:30 PM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $6
    Travel Time is 17h 5m shorter, and you will save $71

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 66h 0m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:40 PM San Diego San Ysidro Transit Center  Economy $244
Flix Mexico 65h 35m 11:05 PM Mexico City Fórum Buenavista 2:40 PM San Diego San Ysidro Transit Center  Economy $244
Flix Mexico 68h 35m 4:00 PM Mexico City San Pedro Santa Clara Bus Stop 10:35 AM San Diego San Ysidro Transit Center  Economy $308
Flix Mexico 68h 10m 4:25 PM Mexico City Fórum Buenavista 10:35 AM San Diego San Ysidro Transit Center  Economy $308
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $90? You can find the corresponding connections below.
    • Busbud
      46h 0m
      0
      10:30 PM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      3:33 PM
      Tijuana, BC
      Centro Bus Stop
      0
      Busbud
      Economy
      $148
      • Waiting Time 1h 27m
    • FlixBus
      1h 30m
      0
      5:00 PM
      Tijuana, BC
      Central Bus Station
      6:30 PM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $6
    Travel Time is 17h 35m shorter, and you will save $90

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 66h 55m 10:25 PM Mexico City Fórum Buenavista 3:20 PM San Diego Old Town Transit Center  Economy $255
Flix Mexico 67h 15m 10:25 PM Mexico City Fórum Buenavista 3:40 PM San Diego SDSU Transit Center  Economy $257
Flix Mexico 69h 20m 10:25 PM Mexico City Fórum Buenavista 5:45 PM San Diego Old Town Transit Center  Economy $264
Flix Mexico 73h 5m 10:25 PM Mexico City Fórum Buenavista 9:30 PM San Diego Seaport Village  Economy $268
Flix Mexico 68h 10m 4:25 PM Mexico City Fórum Buenavista 10:35 AM San Diego San Ysidro Transit Center  Economy $276
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $101? You can find the corresponding connections below.
    • Busbud
      46h 0m
      0
      10:30 PM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      3:33 PM
      Tijuana, BC
      Centro Bus Stop
      0
      Busbud
      Economy
      $148
      • Waiting Time 1h 27m
    • FlixBus
      1h 30m
      0
      5:00 PM
      Tijuana, BC
      Central Bus Station
      6:30 PM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $6
    Travel Time is 18h 55m shorter, and you will save $101

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 68h 35m 4:00 PM Mexico City San Pedro Santa Clara Bus Stop 10:35 AM San Diego San Ysidro Transit Center  Economy $257
Flix Mexico 68h 10m 4:25 PM Mexico City Fórum Buenavista 10:35 AM San Diego San Ysidro Transit Center  Economy $257
Flix Mexico 74h 5m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 10:45 PM San Diego San Ysidro Transit Center  Economy $318
Flix Mexico 73h 40m 11:05 PM Mexico City Fórum Buenavista 10:45 PM San Diego San Ysidro Transit Center  Economy $318
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $103? You can find the corresponding connections below.
    • Busbud
      46h 0m
      0
      10:30 PM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      3:33 PM
      Tijuana, BC
      Centro Bus Stop
      0
      Busbud
      Economy
      $148
      • Waiting Time 1h 27m
    • FlixBus
      1h 30m
      0
      5:00 PM
      Tijuana, BC
      Central Bus Station
      6:30 PM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $6
    Travel Time is 20h 10m shorter, and you will save $103

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 66h 0m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:40 PM San Diego San Ysidro Transit Center  Economy $219
Flix Mexico 65h 35m 11:05 PM Mexico City Fórum Buenavista 2:40 PM San Diego San Ysidro Transit Center  Economy $219
Flix Mexico 65h 30m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:10 PM San Diego Old Town Transit Center  Economy $220
Flix Mexico 65h 5m 11:05 PM Mexico City Fórum Buenavista 2:10 PM San Diego Old Town Transit Center  Economy $220
Flix Mexico 75h 10m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 11:50 PM San Diego Old Town Transit Center  Economy $244
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $65? You can find the corresponding connections below.
    • Busbud
      46h 0m
      0
      10:30 PM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      3:33 PM
      Tijuana, BC
      Centro Bus Stop
      0
      Busbud
      Economy
      $148
      • Waiting Time 1h 27m
    • FlixBus
      1h 30m
      0
      5:00 PM
      Tijuana, BC
      Central Bus Station
      6:30 PM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $6
    Travel Time is 17h 5m shorter, and you will save $65

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 65h 30m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:10 PM San Diego Old Town Transit Center  Economy $220
Flix Mexico 65h 5m 11:05 PM Mexico City Fórum Buenavista 2:10 PM San Diego Old Town Transit Center  Economy $220
Flix Mexico 73h 35m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 10:15 PM San Diego Seaport Village  Economy $221
Flix Mexico 65h 0m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 1:40 PM San Diego La Jolla Village  Economy $221
Flix Mexico 66h 0m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:40 PM San Diego San Ysidro Transit Center  Economy $221
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $66? You can find the corresponding connections below.
    • Busbud
      46h 0m
      0
      10:30 PM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      3:33 PM
      Tijuana, BC
      Centro Bus Stop
      0
      Busbud
      Economy
      $148
      • Waiting Time 1h 27m
    • FlixBus
      1h 30m
      0
      5:00 PM
      Tijuana, BC
      Central Bus Station
      6:30 PM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $6
    Travel Time is 17h 0m shorter, and you will save $66

Best Price Offer: The price for the cheapest bus from Mexico City to San Diego is $218 on 1/8/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Mexico City and San Diego

See here how frequent the connections between Mexico City and San Diego are, during different times and days of the week.
Tuesday is the busiest day, with more than 28 daily buses from Mexico City to San Diego. Sunday has instead the fewest connections, with only 4 daily coaches between Mexico City and San Diego.
The busiest time of the day is the Evening, with 43 buses from Mexico City to San Diego, while Morning sees the fewest connections between Mexico City and San Diego, with 7 offers.

Facts about the bus from Mexico City to San Diego

Compare all providers like Flix Mexico that travel 10 times every day by bus from Mexico City to San Diego in one click! Book your bus ticket from Mexico City to San Diego starting from $218!

Cheapest Bus $218
Fastest Bus 62h 35m
Earliest Bus 11:55 AM
Latest Bus 11:05 PM
Daily Bus Routes 10 Ø
Distance 1,443.3 miles
Bus Companies Flix Mexico

Cheapest bus connections from Mexico City to San Diego

Every day, 10 buses from 1 bus companies leave Mexico City for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/17/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/14
Monday 12/15
Tuesday 12/16
Wednesday 12/17
$221
Thursday 12/18
$277
Friday 12/19
$244
Saturday 12/20
$276
Sunday 12/21
$257
Monday 12/22
$220
Tuesday 12/23
$221
Wednesday 12/24
$220
Thursday 12/25
$244
Friday 12/26
$227
Saturday 12/27
$226
Sunday 12/28
$226
Monday 12/29
$220
Tuesday 12/30
$225
Wednesday 12/31
$227
Thursday 01/01
$255
Friday 01/02
$239
Saturday 01/03
$234
Sunday 01/04
$223
Monday 01/05
$220
Tuesday 01/06
$221
Wednesday 01/07
$219
Thursday 01/08
$218
Friday 01/09
$221
Saturday 01/10

The cheapest time to travel from Mexico City to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Mexico City to San Diego, for the next 30 days.
With a price starting from $217, Monday is the cheapest day for a bus from Mexico City to San Diego. Sunday instead is the most expensive day with prices starting from $223.
Evening is the cheapest day time for bus tickets from Mexico City to San Diego, with $219. Morning is the most expensive time of the day with prices starting from $231.

How to save money travelling from Mexico City to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mexico City to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mexico City to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mexico City to San Diego are also emptier.

All bus stations and stops in Mexico City and San Diego

In the map below, you can see where to find all bus stations in Mexico City and San Diego.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mexico City to San Diego? Compare all modes of transports from Mexico City to San Diego.

Service and Comfort on the bus from Mexico City to San Diego

Want to know which seat classes are available on the buses from Mexico City to San Diego? Or which bus companies serve the route Mexico City to San Diego? Below you will find answers to your questions.

FAQs about the Mexico City to San Diego bus

How much does a Mexico City San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $218 and takes 64h 0m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Mexico City to San Diego?

This route is offered by 1 companies with a range of ticket prices between $218 and $319. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Mexico City to San Diego each day?

Every day, the Mexico City to San Diego bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mexico City to San Diego take?

The fastest bus from Mexico City to San Diego is offered by Flix Mexico and takes 62h 35m. Bus tickets for this connection cost $221. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mexico City to San Diego?

The earliest bus arriving in San Diego from Mexico City starts at 11:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mexico City to San Diego?

The latest bus trip departing from Mexico City for San Diego starts at 11:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mexico City San Diego route?

When traveling by bus from Mexico City to San Diego, passengers can travel with Flix Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mexico City and San Diego?

You can check all the direct connections between Mexico City and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Flix Mexico.

What can I take with me on the Mexico City to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mexico City San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mexico City San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mexico City to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Mexico City to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between Mexico City and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mexico City to San Diego?

Prices and availability for 10 trips between Mexico City and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mexico City to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mexico City and to San Diego

Here’s an overview of the most popular bus routes to Mexico City and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
From Oaxaca de Juárez to Mexico City bus From Oaxaca de Juárez to Mexico City bus
Buses from Puebla City, PL to Mexico City Buses from Puebla City, PL to Mexico City
Guanajuato to Mexico City bus Guanajuato to Mexico City bus
Buses Taxco to Mexico City Buses Taxco to Mexico City
Bus Long Beach - San Diego Bus Long Beach - San Diego
Houston to San Diego bus Houston to San Diego bus
Bus Santa Ana, CA to San Diego Bus Santa Ana, CA to San Diego
Bus New York to San Diego Bus New York to San Diego
Popular Airport Shuttles to Mexico City and to San Diego
CheckMyBus › Buses in Mexico › Bus to Mexico City › Bus to San Diego

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