Which bus from Mexico City to San Diego is the cheapest?

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Compare all timetables for the bus from Mexico City to San Diego

Here is a selection of the cheapest bus trips from the schedule from Mexico City to San Diego from various bus operators like Flix Mexico for the next days.

today
$219
tomorrow
$218
Saturday
$250
Sunday
$227
Monday
$215
Tuesday
$216
Wednesday
$215

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 66h 0m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:40 PM San Diego San Ysidro Transit Center  Economy $219
Flix Mexico 65h 35m 11:05 PM Mexico City Fórum Buenavista 2:40 PM San Diego San Ysidro Transit Center  Economy $219
Flix Mexico 68h 35m 4:00 PM Mexico City San Pedro Santa Clara Bus Stop 10:35 AM San Diego San Ysidro Transit Center  Economy $354
Flix Mexico 68h 10m 4:25 PM Mexico City Fórum Buenavista 10:35 AM San Diego San Ysidro Transit Center  Economy $354
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $39? You can find the corresponding connections below.
    • ClickBus MX
      49h 30m
      0
      10:30 AM
      Mexico City
      Norte Bus Station
      4:20 AM
      Tijuana, BC
      Centro Bus Stop
      0
      ClickBus MX
      Economy
      $175
      • Waiting Time 3h 55m
    • FlixBus
      1h 45m
      0
      8:15 AM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      10:00 AM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $5
    Travel Time is 14h 5m shorter, and you will save $39

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 66h 0m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:40 PM San Diego San Ysidro Transit Center  Economy $218
Flix Mexico 65h 35m 11:05 PM Mexico City Fórum Buenavista 2:40 PM San Diego San Ysidro Transit Center  Economy $218
Flix Mexico 68h 35m 4:00 PM Mexico City San Pedro Santa Clara Bus Stop 10:35 AM San Diego San Ysidro Transit Center  Economy $268
Flix Mexico 68h 10m 4:25 PM Mexico City Fórum Buenavista 10:35 AM San Diego San Ysidro Transit Center  Economy $268
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $96? You can find the corresponding connections below.
    • Busbud
      61h 30m
      0
      10:30 PM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      3:33 PM
      Tijuana, BC
      Centro Bus Stop
      0
      Busbud
      Economy
      $117
      • Waiting Time 16h 42m
    • FlixBus
      1h 45m
      0
      8:15 AM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      10:00 AM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $5
    Travel Time is 2h 5m shorter, and you will save $96

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 69h 55m 4:25 PM Mexico City Fórum Buenavista 12:20 PM San Diego San Ysidro Transit Center  Economy $250
Flix Mexico 73h 40m 11:05 PM Mexico City Fórum Buenavista 10:45 PM San Diego San Ysidro Transit Center  Economy $266
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $128? You can find the corresponding connections below.
    • Busbud
      61h 30m
      0
      10:30 PM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      3:33 PM
      Tijuana, BC
      Centro Bus Stop
      0
      Busbud
      Economy
      $117
      • Waiting Time 16h 42m
    • FlixBus
      1h 45m
      0
      8:15 AM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      10:00 AM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $5
    Travel Time is 6h 25m shorter, and you will save $128

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 75h 10m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 11:50 PM San Diego Old Town Transit Center  Economy $227
Flix Mexico 74h 45m 11:05 PM Mexico City Fórum Buenavista 11:50 PM San Diego Old Town Transit Center  Economy $227
Flix Mexico 73h 35m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 10:15 PM San Diego Seaport Village  Economy $227
Flix Mexico 73h 10m 11:05 PM Mexico City Fórum Buenavista 10:15 PM San Diego Seaport Village  Economy $227
Flix Mexico 69h 45m 4:00 PM Mexico City San Pedro Santa Clara Bus Stop 11:45 AM San Diego Old Town Transit Center  Economy $249
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $105? You can find the corresponding connections below.
    • Busbud
      61h 30m
      0
      10:30 PM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      3:33 PM
      Tijuana, BC
      Centro Bus Stop
      0
      Busbud
      Economy
      $117
      • Waiting Time 16h 42m
    • FlixBus
      1h 45m
      0
      8:15 AM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      10:00 AM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $5
    Travel Time is 6h 15m shorter, and you will save $105

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 65h 30m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:10 PM San Diego Old Town Transit Center  Economy $215
Flix Mexico 65h 5m 11:05 PM Mexico City Fórum Buenavista 2:10 PM San Diego Old Town Transit Center  Economy $215
Flix Mexico 65h 0m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 1:40 PM San Diego La Jolla Village  Economy $217
Flix Mexico 64h 35m 11:05 PM Mexico City Fórum Buenavista 1:40 PM San Diego La Jolla Village  Economy $217
Flix Mexico 66h 0m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:40 PM San Diego San Ysidro Transit Center  Economy $218
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $93? You can find the corresponding connections below.
    • Busbud
      61h 30m
      0
      10:30 PM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      3:33 PM
      Tijuana, BC
      Centro Bus Stop
      0
      Busbud
      Economy
      $117
      • Waiting Time 16h 42m
    • FlixBus
      1h 45m
      0
      8:15 AM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      10:00 AM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $5
    Travel Time is 1h 5m shorter, and you will save $93

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 66h 0m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:40 PM San Diego San Ysidro Transit Center  Economy $216
Flix Mexico 65h 35m 11:05 PM Mexico City Fórum Buenavista 2:40 PM San Diego San Ysidro Transit Center  Economy $216
Flix Mexico 68h 30m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 5:10 PM San Diego San Ysidro Transit Center  Economy $217
Flix Mexico 68h 5m 11:05 PM Mexico City Fórum Buenavista 5:10 PM San Diego San Ysidro Transit Center  Economy $217
Flix Mexico 72h 40m 11:55 AM Mexico City San Pedro Santa Clara Bus Stop 10:35 AM San Diego San Ysidro Transit Center  Economy $250
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $94? You can find the corresponding connections below.
    • Busbud
      61h 30m
      0
      10:30 PM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      3:33 PM
      Tijuana, BC
      Centro Bus Stop
      0
      Busbud
      Economy
      $117
      • Waiting Time 16h 42m
    • FlixBus
      1h 45m
      0
      8:15 AM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      10:00 AM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $5
    Travel Time is 2h 5m shorter, and you will save $94

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Flix Mexico 65h 30m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:10 PM San Diego Old Town Transit Center  Economy $215
Flix Mexico 65h 5m 11:05 PM Mexico City Fórum Buenavista 2:10 PM San Diego Old Town Transit Center  Economy $215
Flix Mexico 66h 0m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 2:40 PM San Diego San Ysidro Transit Center  Economy $218
Flix Mexico 65h 35m 11:05 PM Mexico City Fórum Buenavista 2:40 PM San Diego San Ysidro Transit Center  Economy $218
Flix Mexico 73h 35m 10:40 PM Mexico City San Pedro Santa Clara Bus Stop 10:15 PM San Diego Seaport Village  Economy $220
  • Did you know that if you travel from Mexico City to San Diego via Tijuana, BC, you can save more than $93? You can find the corresponding connections below.
    • Busbud
      61h 30m
      0
      10:30 PM
      Mexico City
      Instituto Politécnico Nacional Bus Stop
      3:33 PM
      Tijuana, BC
      Centro Bus Stop
      0
      Busbud
      Economy
      $117
      • Waiting Time 16h 42m
    • FlixBus
      1h 45m
      0
      8:15 AM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      10:00 AM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $5
    Travel Time is 1h 35m shorter, and you will save $93

Best Price Offer: The price for the cheapest bus from Mexico City to San Diego is $215 on 12/8/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Mexico City and San Diego

See here how frequent the connections between Mexico City and San Diego are, during different times and days of the week.
Monday is the busiest day, with more than 22 daily buses from Mexico City to San Diego. Saturday has instead the fewest connections, with only 2 daily coaches between Mexico City and San Diego.
The busiest time of the day is the Evening, with 37 buses from Mexico City to San Diego, while Morning sees the fewest connections between Mexico City and San Diego, with 4 offers.

Facts about the bus from Mexico City to San Diego

Compare all providers like Flix Mexico that travel 8 times every day by bus from Mexico City to San Diego in one click! Book your bus ticket from Mexico City to San Diego starting from $215!

Cheapest Bus $215
Fastest Bus 62h 35m
Earliest Bus 4:00 PM
Latest Bus 11:05 PM
Daily Bus Routes 8 Ø
Distance 1,443.3 miles
Bus Companies Flix Mexico

Cheapest bus connections from Mexico City to San Diego

Every day, 8 buses from 1 bus companies leave Mexico City for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 11/30
Monday 12/01
Tuesday 12/02
Wednesday 12/03
Thursday 12/04
$219
Friday 12/05
$218
Saturday 12/06
$250
Sunday 12/07
$227
Monday 12/08
$215
Tuesday 12/09
$216
Wednesday 12/10
$215
Thursday 12/11
$216
Friday 12/12
$217
Saturday 12/13
$224
Sunday 12/14
$222
Monday 12/15
$222
Tuesday 12/16
$219
Wednesday 12/17
$220
Thursday 12/18
$221
Friday 12/19
$220
Saturday 12/20
$236
Sunday 12/21
$236
Monday 12/22
$219
Tuesday 12/23
$223
Wednesday 12/24
Thursday 12/25
$235
Friday 12/26
$223
Saturday 12/27

The cheapest time to travel from Mexico City to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Mexico City to San Diego, for the next 30 days.
With a price starting from $215, Monday is the cheapest day for a bus from Mexico City to San Diego. Saturday instead is the most expensive day with prices starting from $224.
Evening is the cheapest day time for bus tickets from Mexico City to San Diego, with $215. Morning is the most expensive time of the day with prices starting from $227.

How to save money travelling from Mexico City to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mexico City to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mexico City to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mexico City to San Diego are also emptier.

All bus stations and stops in Mexico City and San Diego

In the map below, you can see where to find all bus stations in Mexico City and San Diego.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mexico City to San Diego? Compare all modes of transports from Mexico City to San Diego.

Service and Comfort on the bus from Mexico City to San Diego

Want to know which seat classes are available on the buses from Mexico City to San Diego? Or which bus companies serve the route Mexico City to San Diego? Below you will find answers to your questions.

FAQs about the Mexico City to San Diego bus

How much does a Mexico City San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $215 and takes 63h 30m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Mexico City to San Diego?

This route is offered by 1 companies with a range of ticket prices between $215 and $354. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Mexico City to San Diego each day?

Every day, the Mexico City to San Diego bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mexico City to San Diego take?

The fastest bus from Mexico City to San Diego is offered by Flix Mexico and takes 62h 35m. Bus tickets for this connection cost $217. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mexico City to San Diego?

The earliest bus arriving in San Diego from Mexico City starts at 4:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mexico City to San Diego?

The latest bus trip departing from Mexico City for San Diego starts at 11:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mexico City San Diego route?

When traveling by bus from Mexico City to San Diego, passengers can travel with Flix Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mexico City and San Diego?

You can check all the direct connections between Mexico City and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Flix Mexico.

What can I take with me on the Mexico City to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mexico City San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mexico City San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mexico City to San Diego on your planned travel date.

Available seat classes which are offered on the bus route Mexico City to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mexico City and to San Diego

Here’s an overview of the most popular bus routes to Mexico City and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
From Oaxaca de Juárez to Mexico City bus From Oaxaca de Juárez to Mexico City bus
Buses from Puebla City, PL to Mexico City Buses from Puebla City, PL to Mexico City
Guanajuato to Mexico City bus Guanajuato to Mexico City bus
Buses Taxco to Mexico City Buses Taxco to Mexico City
Bus Long Beach - San Diego Bus Long Beach - San Diego
Houston to San Diego bus Houston to San Diego bus
Bus Santa Ana, CA to San Diego Bus Santa Ana, CA to San Diego
Bus New York to San Diego Bus New York to San Diego
Popular Airport Shuttles to Mexico City and to San Diego
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